AMPK
AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.
Products of "AMPK"
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Karanjin
CAS:Karanjin, a flavonoid from karanja seeds, boosts GLUT4, AMPK in muscles, and triggers cancer cell apoptosis.Formula:C18H12O4Purity:99.01%Color and Shape:SolidMolecular weight:292.29ON123300
CAS:ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formula:C24H27N7OPurity:99.22% - 99.53%Color and Shape:SolidMolecular weight:429.52Kudinoside D
CAS:Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.Formula:C47H72O17Purity:99.66% - 99.88%Color and Shape:SolidMolecular weight:909.06Ref: TM-TN1836
1mg126.00€5mg284.00€10mg395.00€25mg610.00€50mg827.00€100mg1,111.00€200mg1,501.00€1mL*10mM (DMSO)341.00€MT 63-78
CAS:MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).Formula:C21H14N2O2Purity:97.11%Color and Shape:SolidMolecular weight:326.35RGX-202
CAS:RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.Formula:C4H9N3O2Purity:99.67% - 99.8%Color and Shape:SolidMolecular weight:131.13HDAC11-IN-2
CAS:HDAC11-IN-2 (compound B6) is a highly selective inhibitor of Histone Deacetylase 11 (HDAC11). It demonstrates IC50 values of 51.1 ×10^-3 μM for HDAC11 and 5 μM for HDAC8. HDAC11-IN-2 reduces de novo lipogenesis (DNL) and enhances fatty acid oxidation, which alleviates hepatic lipid accumulation and pathological symptoms in MASLD mice. By inhibiting HDAC11, HDAC11-IN-2 enhances the phosphorylation of AMPKα1 at the Thr172 site, thereby modulating de novo lipogenesis and fatty acid oxidation in the liver.Formula:C25H35N3O3Color and Shape:SolidMolecular weight:425.564BC1618
CAS:BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Formula:C24H24F3NO2Purity:99.95%Color and Shape:SolidMolecular weight:415.45ASP4132
CAS:ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Formula:C46H51F3N6O8S2Purity:98.34%Color and Shape:SolidMolecular weight:937.06Ref: TM-T8432
1mg67.00€2mg96.00€5mg131.00€10mg197.00€25mg358.00€50mg535.00€100mg753.00€1mL*10mM (DMSO)205.00€Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formula:C16H30O2Purity:99.36%Color and Shape:SolidMolecular weight:254.41MK8722
CAS:MK8722 is an effective and systemic activator of pan-AMPK.Formula:C24H20ClN3O4Purity:98.08% - 99.88%Color and Shape:SolidMolecular weight:449.89Ref: TM-T16099
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg226.00€50mg419.00€100mg617.00€1mL*10mM (DMSO)87.00€WH-4-025
CAS:WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Formula:C39H38F3N7O5Purity:99.41%Color and Shape:SolidMolecular weight:741.76Ref: TM-T9219
1mg40.00€2mg52.00€5mg88.00€10mg137.00€25mg264.00€50mg419.00€100mg617.00€1mL*10mM (DMSO)87.00€IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formula:C21H21NO4Purity:98.07% - 98.14%Color and Shape:SolidMolecular weight:351.4Ref: TM-T8841
1mg81.00€5mg170.00€10mg301.00€25mg563.00€50mg805.00€100mg1,111.00€1mL*10mM (DMSO)188.00€AMAROGENTIN
CAS:Amarogentin, extracted from Swertia/Gentiana roots, aids liver cancer prevention/treatment by affecting cell cycle and apoptosis.Formula:C29H30O13Purity:98.75% - ≥95%Color and Shape:SolidMolecular weight:586.54STO-609
CAS:STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.Formula:C19H10N2O3Purity:97.14% - 98.95%Color and Shape:SolidMolecular weight:314.29Ref: TM-T3546
1mg42.00€5mg88.00€10mg127.00€25mg264.00€50mg423.00€100mg655.00€500mg1,359.00€1mL*10mM (DMSO)113.00€AMPK activator 13
AMPK Activator 13 is a potent activator of the AMPK pathway, effectively inhibiting mitotic clonal expansion in 3T3-L1 cells and enhancing mitochondrial oxygenPurity:98%Color and Shape:Odour SolidCimiracemoside C
CAS:Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.Formula:C35H56O9Purity:99.95%Color and Shape:SolidMolecular weight:620.81HL271
CAS:HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.Formula:C13H17ClF3N5OPurity:98%Color and Shape:SolidMolecular weight:351.76MK-3903
CAS:MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Formula:C27H19ClN2O3Purity:98.54% - 98.63%Color and Shape:SolidMolecular weight:454.9Ref: TM-T5187
1mg35.00€5mg80.00€10mg120.00€25mg188.00€50mg354.00€100mg588.00€200mg833.00€1mL*10mM (DMSO)88.00€Vaccarin
CAS:Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.Formula:C32H38O19Purity:99.16% - 99.97%Color and Shape:SolidMolecular weight:726.63Kahweol
CAS:Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormula:C20H26O3Purity:98.07% - 99.86%Color and Shape:Off-White To Yellow SolidMolecular weight:314.42
