AMPK
AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.
Products of "AMPK"
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HTH-01-015
CAS:HTH-01-015 is a selective NUAK1 inhibitor (IC50=100 nM).Formula:C26H28N8OPurity:98.1% - 99.08%Color and Shape:SolidMolecular weight:468.55Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurity:99% - 99.74%Color and Shape:Off-White To Yellow SolidMolecular weight:414.77Metformin
CAS:Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formula:C4H11N5Purity:100% - 99.78Color and Shape:SolidMolecular weight:129.16AICAR
CAS:AICAR (Acadesine) 是一种AMPK 激活剂,引起ZMP积累,模拟AMP对AMPK和AMPKK的刺激作用,常用于糖尿病,心脑血管疾病以及肿瘤相关研究。Formula:C9H14N4O5Purity:98.00% - ≥95%Color and Shape:SolidMolecular weight:258.23Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Formula:C17H16F6N2OPurity:99.97%Color and Shape:SolidMolecular weight:378.31Ref: TM-T0860L
1mg70.00€5mg154.00€10mg225.00€25mg376.00€50mg538.00€100mg755.00€200mg1,017.00€1mL*10mM (DMSO)160.00€YLF-466D
CAS:YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.Formula:C29H20ClNO3Purity:98.04%Color and Shape:SolidMolecular weight:465.93Ref: TM-T13368
1mg37.00€5mg84.00€10mg117.00€25mg198.00€50mg284.00€100mg393.00€200mg540.00€1mL*10mM (DMSO)87.00€AMPK activator 15
AP39 Prodrug 1 (Compound M1) is a mitochondria-targeted H2S prodrug. In hepatocytes, it induces ROS-dependent mild mitochondrial uncoupling, activates mitochondria-associated AMPK, and inhibits Palmitic acid (PA)-induced lipid accumulation.Formula:C53H51BrNO10PSColor and Shape:SolidMolecular weight:1004.92NUAK1-IN-1
NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formula:C25H30N6OColor and Shape:SolidMolecular weight:430.545AMPK activator 12
CAS:AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein for cancer research.Formula:C23H24BrNO2Purity:99.27%Color and Shape:SolidMolecular weight:426.35[6]-Gingerol
CAS:[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Formula:C17H26O4Purity:98% - 99.59%Color and Shape:Light Yellow OilinessMolecular weight:294.39Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurity:98.89% - 99.28%Color and Shape:SolidMolecular weight:265.25Danthron
CAS:Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.Formula:C14H8O4Purity:99.97%Color and Shape:Red Or Red-Yellow Needles Or Leaves (From Alcohol) Physical Description Orange Crystalline Powder Almost Odorless And Tasteless (Ntp 1992)Molecular weight:240.21Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFormula:C19H18NO4Purity:98.08% - 99.18%Color and Shape:SolidMolecular weight:324.35Aldometanib
CAS:Aldometanib (LXY-05-029) is an oral aldolase inhibitor that maintains metabolic balance by blocking FBP and activating lysosomal AMPK.Formula:C27H43Cl2IN2Purity:100% - 98.8%Color and Shape:SolidMolecular weight:593.46Ref: TM-T60122
1mg46.00€5mg90.00€10mg130.00€25mg274.00€50mg405.00€100mg600.00€200mg837.00€500mg1,283.00€1mL*10mM (DMSO)134.00€AMPK-IN-6
AMPK-IN-6 (compound 13a) is a potent AMPK inhibitor with an IC50 value of 0.093 µM. It induces apoptosis and suppresses autophagy. Additionally, AMPK-IN-6 exhibits antiproliferative activity and holds potential for research into pulmonary arterial hypertension.Formula:C18H20FN5OMolecular weight:341.383Gomisin J
CAS:Gomisin J is a natural product and have vasodilatory activity.Formula:C22H28O6Purity:99.59% - 99.69%Color and Shape:SolidMolecular weight:388.45Ref: TM-T3904
1mg47.00€2mg65.00€5mg119.00€10mg188.00€25mg329.00€50mg490.00€100mg700.00€1mL*10mM (DMSO)97.00€Dorsomorphin dihydrochloride
CAS:Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity onFormula:C24H25N5O·2HClPurity:97.74% - 99.89%Color and Shape:SolidMolecular weight:472.41Ref: TM-T6146
2mg35.00€5mg51.00€10mg70.00€25mg135.00€50mg235.00€100mg424.00€500mg938.00€1mL*10mM (DMSO)57.00€ZLN 024 hydrochloride
CAS:ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).Formula:C13H14BrClN2OSPurity:99.86%Color and Shape:SolidMolecular weight:361.68Buformin hydrochloride
CAS:Buformin hydrochloride, an oral biguanide antidiabetic, activates AMPK, enhances insulin sensitivity, and inhibits hepatic glucose production.Formula:C6H16ClN5Purity:97.83%Color and Shape:SolidMolecular weight:193.68EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formula:C30H36Br2N4O2Purity:99.48%Color and Shape:SolidMolecular weight:644.4
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