PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Products of "PI3K"
Sort by
Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFormula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24Ref: TM-TN1299
1mg178.00€5mg540.00€10mg715.00€25mg1,103.00€50mg1,491.00€100mg2,005.00€500mg4,010.00€1mL*10mM (DMSO)442.00€BGT226
CAS:BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Formula:C28H25F3N6O2Purity:100% - 98.40%Color and Shape:SolidMolecular weight:534.53Ref: TM-T6072L
1mg52.00€5mg114.00€10mg187.00€25mg411.00€50mg607.00€100mg847.00€1mL*10mM (DMSO)156.00€PI3Kγ inhibitor 1
CAS:PI3Kγ inhibitor 1 is a inhibitor of PI3Kδ and PI3Kγ.Formula:C32H26N8O2SPurity:98%Color and Shape:SolidMolecular weight:586.67PF-06843195
CAS:PF-06843195 is a potent and selective PI3Kα inhibitor prevents it catalyzing the conversion of PIP2 to PIP3, inhibit the activation of AKT, anti-tumor .Formula:C20H25F3N8O4Purity:98.01%Color and Shape:SolidMolecular weight:498.46Glaucocalyxin A
CAS:Glaucocalyxin A improves drug delivery, activates apoptosis, inhibits cell growth, with potential as an antiplatelet agent.Formula:C20H28O4Purity:99.55% - 99.56%Color and Shape:SolidMolecular weight:332.43PF-04979064
CAS:PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor(Ki of 0.13 nM and 1.42 nM,respectively).Formula:C24H26N6O3Purity:98.04% - ≥98%Color and Shape:SolidMolecular weight:446.5Quercetin
CAS:Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Formula:C15H10O7Purity:96.29% - 98.05%Color and Shape:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Molecular weight:302.24KU-0060648
CAS:KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ.Formula:C33H34N4O4SPurity:98.75%Color and Shape:SolidMolecular weight:582.71IC-87114
CAS:IC-87114 is a specific PI3Kδ inhibitor(IC50=0.5 μM).Formula:C22H19N7OPurity:100% - 97.97%Color and Shape:SolidMolecular weight:397.43Ref: TM-T2660
2mg39.00€5mg57.00€10mg90.00€25mg145.00€50mg240.00€100mg378.00€200mg552.00€1mL*10mM (DMSO)64.00€Esculetin
CAS:Esculetin: a coumarin from plants with anti-edema, anti-inflammatory, anti-tumor properties; inhibits LOs.Formula:C9H6O4Purity:98.03% - 99.76%Color and Shape:Yellow Crystalline PowderMolecular weight:178.14WYE-687
CAS:WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).Formula:C28H32N8O3Purity:98.98%Color and Shape:SolidMolecular weight:528.61PI3Kδ-IN-23
CAS:PI3Kδ-IN-23 (compound A11) is a potent inhibitor of PI3Kδ, with an IC50 of 0.27 nM. It binds to PI3Kδ through covalent interaction with Lys779 and plays a significant role in cancer research.Formula:C30H30N6O5Molecular weight:554.596mTOR inhibitor 9f
CAS:mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for mTOR and PI3Kα, respectively.Formula:C25H23N5O2SPurity:98.39%Color and Shape:SoildMolecular weight:457.55PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48PI3Kδ-IN-3
CAS:PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.Formula:C28H24N6O3Purity:98.43%Color and Shape:SolidMolecular weight:492.53Lupiwighteone
CAS:Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Formula:C20H18O5Purity:99.20%Color and Shape:SolidMolecular weight:338.35CAL-130 Hydrochloride
CAS:CAL-130 Hydrochloride is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Formula:C23H23ClN8OColor and Shape:SolidMolecular weight:462.94Parsaclisib hydrochloride
CAS:Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity.Formula:C20H23Cl2FN6O2Purity:98%Color and Shape:SolidMolecular weight:469.34SRX3207
CAS:SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.Formula:C29H29N7O3SPurity:99.85%Color and Shape:SolidMolecular weight:555.65AZD8186
CAS:AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).Formula:C24H25F2N3O4Purity:99.89% - 99.91%Color and Shape:SolidMolecular weight:457.47Ref: TM-T6773
2mg46.00€5mg66.00€10mg99.00€25mg168.00€50mg304.00€100mg505.00€500mg1,121.00€1mL*10mM (DMSO)72.00€
