PI3K
PI3K inhibitors are compounds that block the activity of Phosphoinositide 3-Kinases (PI3Ks), a family of enzymes involved in a wide range of cellular processes, including growth, proliferation, survival, and metabolism. The PI3K/Akt/mTOR pathway is often dysregulated in cancer, making PI3K a key target for cancer therapy. PI3K inhibitors are critical tools for studying signal transduction, cancer biology, and the development of targeted therapies. At CymitQuimica, we provide a variety of PI3K inhibitors to support your research in cell signaling, oncology, and therapeutic development.
Products of "PI3K"
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Acalisib
CAS:Acalisib (CAL-120) (GS-9820) is a potent and selective inhibitor of PI3Kδ.Formula:C21H16FN7OPurity:98.99% - ≥95%Color and Shape:SolidMolecular weight:401.4AZD-8835
CAS:AZD-8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ (IC50: 431/90 nM).Formula:C22H31N9O3Purity:98.22% - 98.49%Color and Shape:SolidMolecular weight:469.54FD2056
CAS:FD2056 is a potent, orally active PI3K inhibitor, with IC50 values of 0.30, 0.80, 1.10, and 0.42 nM against PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ, respectively.Formula:C23H17ClN6O2SPurity:98%Color and Shape:SolidMolecular weight:476.94MSC2360844
CAS:MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).Formula:C26H27FN4O5SPurity:100% - 99.32%Color and Shape:SolidMolecular weight:526.58Ref: TM-T12115
1mg52.00€5mg116.00€10mg182.00€25mg354.00€50mg568.00€100mg900.00€200mg1,206.00€1mL*10mM (DMSO)135.00€Copanlisib
CAS:Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.Formula:C23H28N8O4Purity:99.02% - 99.88%Color and Shape:SolidMolecular weight:480.52Duvelisib (R enantiomer) hydrochloride
Duvelisib (R enantiomer) hydrochloride (INK1197 R enantiomer HCl) is a PI3K inhibitor.Formula:C22H18Cl2N6OPurity:99.76% - 99.87%Color and Shape:SoildMolecular weight:453.32Ref: TM-T11129L
1mg313.00€5mg758.00€10mg1,035.00€25mg1,568.00€50mg2,118.00€100mg2,783.00€1mL*10mM (DMSO)945.00€PH14
PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for PI3Kα and 24.5 nM for HDAC3.Purity:98%Color and Shape:Odour Solid(+)-Nortrachelogenin
CAS:(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.Formula:C20H22O7Purity:99.64%Color and Shape:SolidMolecular weight:374.38Recilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Formula:C16H13ClO4SPurity:98.85% - 98.96%Color and Shape:SolidMolecular weight:336.79Ref: TM-T13862
1mg46.00€2mg59.00€5mg87.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)105.00€PI3K/VEGFR2-IN-1
CAS:PI3K/VEGFR2-IN-1 is a potent dual inhibitor targeting both PI3K and VEGFR2 with IC50 values of 2.21 μM for PI3K and 68 μM for VEGFR2, respectively.Formula:C17H14ClN3OSPurity:98%Color and Shape:SolidMolecular weight:343.83PQR530
CAS:PQR530, a potent dual PI3K/mTORC1/2 inhibitor, blocks PKB and pS6 phosphorylation (IC50: 0.07 μM) and has antitumor properties.Formula:C18H23F2N7O2Purity:99.50%Color and Shape:SolidMolecular weight:407.42Duvelisib (R enantiomer)
CAS:Duvelisib R enantiomer (IPI-145 R enantiomer) is an enantiomer of Duvelisib with lower activity. Duvelisib is a PI3K inhibitor.Formula:C22H17ClN6OPurity:98%Color and Shape:SolidMolecular weight:416.86Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFormula:C26H44NNaO5SPurity:99.79% - 99.93%Color and Shape:SolidMolecular weight:505.69Rigosertib sodium
CAS:Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.Formula:C21H24NNaO8SPurity:98% - 99.37%Color and Shape:SolidMolecular weight:473.47PI3Kδ-IN-18
Se15, a selective PI3Kδ inhibitor, exhibits potency with an IC50 value of less than 0.1nM and is utilized in autoimmune research [1].Purity:98%Color and Shape:Odour SolidRigosertib
CAS:Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.Formula:C21H25NO8SPurity:99.53%Color and Shape:SolidMolecular weight:451.49TGX-115
CAS:TGX-115 inhibits PI 3-K p110β (IC50=0.13μM) & p110δ (IC50=0.63μM), treats various cardiovascular diseases.Formula:C20H20N2O3Purity:99.2%Color and Shape:SolidMolecular weight:336.38Ref: TM-T24873
1mg200.00€5mg472.00€10mg645.00€25mg905.00€50mg1,121.00€100mg1,425.00€200mg1,863.00€1mL*10mM (DMSO)389.00€Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48Vacuolin-1
CAS:Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.Formula:C26H24IN7OPurity:97.20% - 98.45%Color and Shape:SolidMolecular weight:577.4225(R,S)-Ruscogenin
CAS:25(R,S)-Ruscogenin is able to regulate the PI3K/Akt/mTOR signalling pathway, and hinder the metastasis of hepatocellular carcinoma.Formula:C27H42O4Purity:99.32% - 99.89%Color and Shape:SolidMolecular weight:430.62
