Oligosaccharides

4-Methoxyphenyl 4-O-[4-O-(3,4,6-tri-O-acetyl-2,4,6-trimethylbenzoyl)-b-D-glucopyranosyl]-3,6-di-O-[α-(1→2)-bromoacetamido]-b-D-glucopyranoside is a complex carbohydrate which belongs to the group of glycosides. It was synthesized by modification of the natural bovine erythrocyte glycoglycerolipid (glycolipid) and monosaccharide (monoglyceride). The synthesis is based on a series of reactions that include methylation and fluorination. This compound has been shown to have high purity and can be made in custom synthesis.

Heparin disaccharide I-A trisodium salt is an oligosaccharide that is a synthetic and modified form of heparin. It is used as a pharmaceutical agent to prevent coagulation, and in the treatment of thrombosis, deep vein thrombosis, pulmonary embolism, and other cardiovascular diseases. This product has been custom synthesized for the modification of sugar structures, fluorination, methylation, sugar modification and click chemistry.

Found in milk with immunoprotective effects against pathogens in newborns and aids development and maturation of the immune system and gut microbiota. Suppresses adhesion and infectivity of bacteria and viruses, such as influenza viruses, HIV-1 and rotaviruses. Inhibits binding of cholera toxin.

This substance is a custom synthesis, which is created in the laboratory. The modification of this product has been done by fluorination, methylation, and monosaccharide synthesis. This substance is a synthetic compound that belongs to the group of oligosaccharides. It is a saccharide that contains an oxygen atom and belongs to the group of complex carbohydrates. It has been shown to be effective against cancer cells in vitro and has been used as a diagnostic agent for breast cancer.

Applications Isotope labelled analogue of Guanosine (G837900), a constituent of nucleic acids. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Miles, et al.: Science, 142, 1458 (1963), Bugg, et al.: Biochem. Biophys. Res. Commun., 3, 436 (1968),

Galb1-3Galb1-4GlcNAcb1-3Galb1-4Glc is a complex carbohydrate that is synthesized from Galb1-4GlcNAcb1-3Galb1-4Glc and 3,6-anhydro-L-galactose. It has been modified with fluorination to prevent degradation. The synthesis of this product may be modified by methylation, glycosylation, or carbonylation. Galb1-3Galb1-4GlcNAcb1-3Galb1-4Glc has CAS No. 443660-52-4 and a purity of 96%. This product is stable at room temperature and may be used in the preparation of vaccines or diagnostic kits.

Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).

2-Acetamido-4-O-{2-acetamido-4-O-[3-O-[2,4-di-O-(2-acetamido-2,6-dideoxyb -D-glucopyranosyl)-a,D -mannopyranosyl]-6-O-[2,6 -di(2 -acetamido)-b -D -glucopyranosyl]-b D mannopyranosyl]] b D mannopyranosyl} 2,6 dideoxy b D glucopyranosyl} 6 O-(a L fucopyranosyl)}

Pentasaccharide derived from chitin

Gala1-3Galb1-4(6-deoxyGlcNAc)-HSA is a custom synthesis of a complex carbohydrate. It is an oligosaccharide with CAS No. and Polysaccharide that has been modified by Methylation, Glycosylation, and Click modification. Carbohydrate is one of the most important macronutrients for human health, as it provides energy and cell building blocks. Sugar (e.g., glucose) is the simplest form of carbohydrate, while saccharide refers to chains of sugar molecules. Gala1-3Galb1-4(6-deoxyGlcNAc)-HSA has been fluorinated and synthesized with high purity in order to be used as a drug delivery system. This drug can be used to treat various diseases such as diabetes mellitus type I or II, cancer, or HIV/AIDS.

Kojitriose is a disaccharide composed of two glucose molecules. It has been shown to have insulin-sensitizing effects in animals and humans. Kojitriose binds to the surface of Streptococcus faecalis and prevents the growth of this bacteria. Kojitriose also has an inhibitory effect on mesenteroides, which are a type of bacterium found in the human gut. This disaccharide is enzymatically hydrolyzed to produce hydrogen fluoride, which inhibits the growth of Streptococcus faecalis and mesenteroides. The enzyme trehalase is responsible for this hydrolysis reaction, while hydroxyl groups act as nucleophiles that react with chloride ions to form hydrogen fluoride.

Gal[2346Ac]b(1-3)GalN3[46Bzd]-b-MP is a modified oligosaccharide with a carbohydrate backbone of 3 mannose and 1 galactose residues. The saccharide is synthesized from the monosaccharides methylated, glycosylated, and then fluorinated. Gal[2346Ac]b(1-3)GalN3[46Bzd]-b-MP has a CAS number of 71769-77-5.

Lactitol is a polyol that is used as a sweetener and has the potential to cause diarrhea. It belongs to the group of sugar alcohols, which are not completely digested by humans. Lactitol is produced from lactose, which is derived from milk. The main clinical relevance of lactitol is its high intestinal permeability, low caloric value, and ability to lower blood glucose levels in diabetics. Lactitol undergoes microbial metabolism through the action of certain bacteria in the colon and can be found in products such as probiotics and food supplements. It has been shown to have beneficial effects on chronic viral hepatitis and may be used for treatment of bacterial translocation. Lactitol also inhibits pge2 production in mice with colitis, leading to decreased inflammatory responses in their small intestines and colon. This inhibition may also lead to suppression of tumor growth or promotion of apoptosis in colorectal cancer cells by inhibiting protein synthesis and cell division.br>

One of the disaccharides produced during the acid reversion of D-mannose.  This mannobiose is the major repeating unit in the mannose chains of plant mannans, galacto- and gluco-mannans. It has been isolated from partial acid hydrolysates of ivory-nut (Phytelephas, macrocarpa) mannan, guaran (Cyamopsis sp.), palmyra palm (Borassus flabelliferer), fenugreek (Trigonella foenum-graecum) and lucerne (Medicago saliva) galactomannans.

Methyl b1-4-D-xylobioside is a bioreactor that binds to the carbohydrate binding domain of the enzyme. It has been shown to be reactive with galactose and other glycosides, and is used as a substrate for electrophotographic analysis. This product also has immobilized properties, which make it suitable for use in an acceptor column in order to purify oligosaccharides or gene products with similar sequences. Methyl b1-4-D-xylobioside is used as a selective inhibitor of tuberculosis by binding to the enzyme mycobactin synthase, which is involved in the biosynthesis of mycolic acids.

Stability Hygroscopic Applications 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic Acid, Sodium Salt, X Hydrate (cas# 123549-14-4 ) is a compound useful in organic synthesis.

Chitoheptaose 7HCl is a synthetic, complex carbohydrate with a CAS number of 68232-35-9. This product is custom synthesized to order and can be modified according to your specifications. It is available in high purity.

4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-D-mannopyranose is a synthetic nonreducing sugar that has been modified with an acetate group at C4 and acetyl groups at C3 and C6. This compound is a white to off white crystalline solid. It is soluble in methanol and formamide. The chemical formula of the compound is CHO.

Applications Labelled analogue of Neomycin, an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.

Non-cytotoxic; biocompatible; used for targeted drug delivery

Monofucosyl-para-lacto-N-neohexaose IV is a monofucosylated glycan consisting of a single pyranose ring. It is a synthetic oligosaccharide that has been modified with Click chemistry to introduce an alkyne group at the reducing end. The alkyne group can be further modified by nucleophilic substitution reactions, such as fluorination, or glycosylation. Monofucosyl-para-lacto-N-neohexaose IV is used in the synthesis of complex carbohydrates.

Stability Hygroscopic Applications Single factor antibiotic comprising about 10% of nebramycin, the aminoglycosidic antibiotic complex produced by Streptomyces tenebrarius. Antibacterial.A representative lot contains d4, d5, d6, d7, d8, and d9. References Koch, K.F., et al.: Antimicrob. Agents Chemother., 309 (1970), Welles, J.S., et al.: Toxicol. Appl. Pharmacol., 22, 332 (1972), Dash, A.K., et al.: Anal. Profiles Drug Subs. Excip., 24, 579 (1996),

Substrate for fucosidase; used in infant formula; improves health in infants

Applications 2-Acetamido-4-O-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-1,6-di-O-N-acetyl-α-D-muramic Acid (cas# 475502-13-7) is a compound useful in organic synthesis.

Applications Ribavirin-13C2 is the labeled analogue of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research. References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986); Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993); Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994); Reichard, O., et al.: Lancet, 351, 83 (1998)

Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. A number of publications have suggested that agarodecaose has properties that include: anti-microbial, antiviral, prebiotic, anti-tumoral, immunomodulatory, anti-inflammatory, glucosidase inhibitory, and hepatoprotective properties.

2-Acetamido-2-deoxy-4-O-(a-L-fucopyranosyl)-D-glucopyranose is a methylated, custom synthesized oligosaccharide. It has been modified to include a fluorine atom at the C4 position on the glucose residue. The product is highly pure and in crystalline form, with a CAS number of 76211-71-7.

2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-6-sulfo-D-glucopyranose sodium salt is a synthetic compound that is used in glycosylation reactions. It can be used for the production of oligosaccharides and complex carbohydrates, as well as for the modification of natural products. 2 Acetamido -2 deoxy -4 O-(b-D galactopyranosyl) -6 sulfo D glucopyranose sodium salt has a purity of 98% and was synthesized by fluorination. The CAS number is 145447 78 5.

A antigen tetrasaccharide Type I I, possible use in antiviral development

Blood group H pentaose type II is a carbohydrate. It is a saccharide with the molecular formula C5H11O4. The saccharide can be modified, for example by fluorination, methylation and glycosylation. The CAS number for this compound is 30517-76-1. This product is custom synthesized and has high purity and good quality.

Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a modification of the carbohydrate, which is a complex carbohydrate. It has been synthesized using Custom synthesis and Oligosaccharide. This product is highly pure, with a purity of 99%. Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-Dpglucopyranoside is used in the synthesis of Monosaccharide and Methylation. It can also be used in Glycosylation and Polysaccharide as well as for sugar or Fluorination.

GM3-ganglioside NBD (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue with nitrobenzoxadiazole (NBD) linked β to position 1 on the reducing terminal glucose residue, in place of the ceramide fatty acid (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain, and melanomas, where it is frequently found to be overexpressed. GM3 ganglioside is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function, and immune disorders (e.g. allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and is a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).

This compound is a glycosylation product of 4-methoxyphenol, 4-O-[2-O-acetyl-3,4-di-O-(2,3,4,6-tetra-O-acetyl-aD-mannopyranosyl)-6-O-benzyl -bD -mannopyrannoside]-, 3,6 -di -O -acetyl-. It has been custom synthesized for your order. This product is offered at high purity and with low background fluorescence.

Methyl 3-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a custom synthesized compound that belongs to the group of complex carbohydrates. It is used in the synthesis of oligosaccharides and polysaccharides. Methyl 3-O-(a-D-mannopyranosyl)-b-D-mannopyranoside can be modified through fluorination, which enhances its properties. This product is available in high purity and with a monosaccharide content of 99%. The CAS number for this compound is 4127757-76-4.

Please enquire for more information about 4'-O-(a-D-Galactopyranosyl)-D-lactose including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Benzyl 2-Acetamido-2-deoxy-4-O-(β-D-galactopyranosyl)-β-_x000D_D-glucopyranoside (cas# 53167-38-7 ) is a compound useful in organic synthesis. References Ohmae, M., et al.: ChemBioChem., 8, 1710 (2007),

Heparin sulfate NS-oligosaccharide NS is a high purity, custom synthesis, sugar-based heparin. Heparin sulfate NS-oligosaccharide NS is designed for use in glycosylation reactions and provides the opportunity to introduce a variety of functional groups including Click modification, fluorination, methylation, and glycosylation. This product contains no animal derived ingredients. Heparin sulfate NS-oligosaccharide NS can be used in a range of applications such as pharmaceuticals, agrochemicals, and food additives.

3-O-(a-D-Galactopyranosyl)-D-glucopyranose is a custom synthesis that can be fluorinated, methylated, and modified with click chemistry. 3-O-(a-D-Galactopyranosyl)-D-glucopyranose is a sugar that can be used in the synthesis of oligosaccharide or polysaccharide. It also has saccharide binding properties. 3-O-(a-D-Galactopyranosyl)-D-glucopyranose is soluble in water and does not react with strong acids such as HCl.

6-Deoxy-6-fluoro-D-lactosylamine (6DFDLA) is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide. It is a polysaccharide that contains a glycosyl linkage between two or more monosaccharides. The carbons of 6DFDLA are derived from glucose and galactose. 6DFDLA is a carbohydrate that can be classified as either simple or complex carbohydrates.