Coumarins

Nordalbergin, a coumarin isolated from the bark of Dalbergia sissoo, can significantly induce the differentiation of HL-60 cells.

Bergaptol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Natural glycoside

Scopolin, a PAL-activity-induced compound, may alleviate rat AIA symptoms by curbing inflammation and angiogenesis, offering a basis for new drugs.

Br-Mmc (4-Bromomethyl-7-methoxycoumarin) is used as a new fluorescence label for fatty acids. It is used for the determination of fatty acids by HPLC or TLC.

DEAC, SE (7-Diethylaminocoumarin-3-carboxy acid) is a blue fluorescent dye for labeling amine-containing organisms. λex of DEAC, SE is 330 nm and λem is 402

Umbelliferone or 7-hydroxycoumarin is a widespread natural product of the coumarin family. It occurs in many familiar plants from the umbelliferae family. Umbelliferone can be used as a fluorescence indicator for metal ions such as copper and calcium. It acts as a pH indicator in the range 6.5-8.9.

The amine-reactive AMCA, SE (7-amino-4-methylcoumarin-3-acetic acid, succinimidyl ester) and its conjugates yield blue-fluorescence (approximate excitation/

Oxypeucedanin methanolate is a naturally occurring furanocoumarin, which is a type of organic compound found predominantly in several citrus plants. This compound is derived from the peels and essential oils of these plants, highlighting its botanical source that is rich in phytochemicals. The mode of action of oxypeucedanin methanolate involves its interaction with biological systems at the molecular level. It is known to exhibit phototoxic properties by forming adducts with cellular macromolecules upon activation by ultraviolet light. Additionally, it may interfere with various biological pathways, potentially offering antioxidant, anti-inflammatory, or antimicrobial effects. In scientific research, oxypeucedanin methanolate is investigated for its potential applications in pharmacology and biochemistry. It serves as a subject of studies exploring new therapeutic agents due to its bioactive characteristics. Moreover, it is used in experimental models to study the effects of natural compounds on human health and disease mechanisms. Researchers are particularly interested in its role in drug development and as a tool for understanding plant-derived secondary metabolites and their interactions within biological systems.

Lactone

Toddanol ((-)-Toddanol) is a coumarin extracted from the roots of Toddalia.

Oxypeucedanin hydrate is a natural furanocoumarin compound, which is derived from various plant sources, such as citrus fruits and members of the Apiaceae family. As a secondary metabolite, it plays a role in plant defense mechanisms against herbivores and pathogens. The mode of action of oxypeucedanin hydrate involves interaction with enzymes and cellular pathways, exhibiting a range of biological activities including antimicrobial, anti-inflammatory, and anti-cancer effects. Its ability to inhibit specific enzymes and modulate signaling pathways makes it a compound of interest for further pharmacological studies. In scientific research, oxypeucedanin hydrate is utilized to explore its potential therapeutic applications. Its diverse biological activities suggest possible uses in developing treatments for infections, inflammatory diseases, and cancer. Researchers continue to investigate its efficacy and mechanisms of action, contributing to the broader understanding of furanocoumarins and their potential benefits in medicine.

7-Hydroxycoumarin is a fluorescent compound, known as a coumarin derivative, which is a naturally occurring chemical found in many plants. Derived from the umbelliferone compound family, it exhibits strong blue fluorescence under UV light due to its unique structural properties. This fluorescence is a result of its molecular conjugation and the electron-donating nature of the hydroxyl group, allowing it to absorb and emit light efficiently. The compound has notable applications in biochemical research areas such as enzyme activity assays, where it serves as a non-radioactive marker. Additionally, its photostability and sensitivity make it an excellent choice for studying cell function and interactions via fluorescence microscopy. In forensic science, 7-Hydroxycoumarin is used for detecting latent fingerprints, taking advantage of its photophysical properties. Furthermore, its utility extends to the pharmaceutical industry, where it contributes to the investigation of metabolic processes involving cytochrome P450 enzymes. Importantly, its biocompatibility and versatile nature underline its significant value in various scientific investigations.

M02744 - 4-Methylumbelliferyl-a-D-galactopyranoside

3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors

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4-Hydroxycoumarin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity.

Esculetin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences.

8-Methoxypsoralen is a furocoumarin compound, which is derived from natural plant sources such as the seeds of the Ammi majus plant. Its primary mode of action involves intercalation into DNA strands and the formation of covalent bonds with pyrimidine bases upon exposure to ultraviolet A (UVA) light. This interaction results in the inhibition of DNA synthesis and cell proliferation. The compound finds extensive applications in the field of dermatology, particularly in PUVA (psoralen and UVA) therapy for the treatment of skin disorders such as psoriasis, vitiligo, and mycosis fungoides. By inducing controlled DNA damage and modulating immune responses, 8-Methoxypsoralen helps reduce the overproduction of skin cells and alleviates symptoms. Its efficacy in repigmenting skin and managing inflammatory skin conditions has been well-documented, making it a valuable agent in therapeutic photochemotherapy protocols.

3-Aminocoumarin (3-aminochromen-2-one) is the key intermediate for the metal complexes.

Lactone

7-(Diethylamino)-3-(1-methyl-2-benzimidazolyl)coumarin is a fluorescent dye, which is synthesized through chemical derivatization of coumarin compounds. Originating from coumarin, a naturally occurring compound in plants, this dye is particularly noted for its ability to fluoresce under UV and visible light. The mode of action involves its excited electron state, which emits light upon returning to a ground state, making it useful for applications requiring visualization under a microscope or spectrometer. This photophysical property is central to its role as a reporter in various biological and chemical assays. Primarily, this compound finds applications in the fields of biochemistry and molecular biology for its utility in fluorescence microscopy, flow cytometry, and cell viability assays. It is an integral tool for tracing biochemical pathways, analyzing cellular components, and assessing physiological functions in living cells. By conjugating with specific biomolecules, researchers can obtain detailed information on molecular interactions and dynamics within complex biological systems, aiding in a deeper understanding of biological processes.

Anomelin is a synthetic anticancer compound, which is derived from complex organic synthesis methodologies. This compound is typically produced through careful laboratory processes due to its intricate chemical structure, which is crafted to target specific molecular pathways involved in cancer cell proliferation. The mode of action of Anomelin involves the inhibition of key enzymes in cell growth pathways, specifically targeting the signaling processes that regulate cell division and apoptosis. By interfering with these pathways, Anomelin can induce cell cycle arrest and promote programmed cell death in malignant cells, thereby inhibiting tumor growth. In terms of uses and applications, Anomelin is primarily explored within the context of oncology research. Scientists are investigating its efficacy in preclinical studies, focusing on its potential to act as a therapeutic agent against various types of cancer, especially those that have shown resistance to conventional treatments. Research is ongoing to determine the specific types of cancers most responsive to Anomelin and to further elucidate its pharmacokinetics and safety profile.

Scopoletin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

7-Hydroxycoumarin-3-carboxylic acid (7-HC-3-CA) is a safe anti-browning agent that inhibits tyrosinase activity, useful for studying food preservation.

Poncimarin is a citrus-derived flavor compound, which is extracted from the peels of citrus fruits. Its mode of action involves mimicking natural citrus flavors, providing authentic taste profiles through a combination of volatile compounds that resemble those found in fresh citrus. The primary application of Poncimarin lies in its utilization as a flavoring agent in the food and beverage industry. It is incorporated to enhance the sensory attributes of products like beverages, confectioneries, and baked goods, delivering a refreshing citrus note that is both recognizable and appealing. Poncimarin's efficacy is attributed to its ability to integrate seamlessly with the existing flavor matrices of these products, ensuring a balanced and natural sensory experience. Its use extends to applications requiring stable, long-lasting flavor profiles, contributing to product innovation and development within sensory science.

Isodemethylwedelolactone (Isodemethylwedelolacton) is a natual product,has Clotting activity.

Esculin analytical standard provided with w/w absolute assay, to be used for quantitative titration.