Coumarins

Lactone

Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.

Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat leukemia cells, it has a strong clastogenic effect . (+)-Heraclenin displays significant levels of antiplasmodial and moderate levels of antimicrobial activities.

Lactone

7-Methylcoumarin is an organic compound classified as a coumarin derivative, which is sourced from various plants and synthesized chemically. Its basic structure consists of a benzopyrone, with a methyl group at the seventh position on the coumarin core, distinguishing it from naturally occurring coumarins. The mode of action of 7-Methylcoumarin largely involves its ability to participate in photophysical and photochemical processes. This reactivity is attributed to its conjugated system, allowing it to absorb ultraviolet (UV) light and potentially generate reactive species. These properties make it valuable in photochemical research and applications requiring UV sensitivity. 7-Methylcoumarin finds uses in several scientific and industrial sectors. In perfumery, it is valued for its pleasant aroma, contributing to the fragrance profiles of various products. In analytical chemistry, it serves as a reference or analysis agent for UV-visible spectroscopic studies. Additionally, its fluorescence properties are exploited in developing fluorescent probes for biological applications, including imaging and diagnostic assays. Its multifaceted applications underscore the importance of 7-Methylcoumarin within both the chemical industry and scientific research.

Lactone

Suberosin epoxide is a naturally occurring compound, classified as a type of sesquiterpene lactone, which is extracted from certain plant species, particularly those belonging to the Rutaceae family. This compound is of significant interest due to its biologically active properties. Its mode of action typically involves the modulation of enzymatic pathways within biological systems, often interacting with cellular proteins and potentially affecting signal transduction processes. The compound has been studied for various applications, primarily in the field of biochemical research, where its potential anti-inflammatory and antimicrobial properties are of particular interest. Suberosin epoxide may also play a role in the development of new therapeutic agents, given its capability to influence key biological pathways. Researchers in pharmacology and biochemistry are exploring its effectiveness and safety in different contexts, focusing on its ability to act as a lead compound for the synthesis of novel drugs. Consequently, its use extends into experimental studies aimed at understanding complex biological mechanisms and exploring potential therapeutic innovations.

4-Ethoxycoumarin has antimicrobial activity.

Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.

Coumarin 314 is a useful organic compound for research related to life sciences. The catalog number is T66908 and the CAS number is 55804-66-5.

Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).

DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal

Marmesinin is a furanocoumarin compound, which is a type of phytochemical derived from certain plant species. It is specifically obtained from the plant Aegle marmelos, commonly known as the bael tree. Marmesinin acts primarily through mechanisms that are characteristic of coumarins, such as influencing biochemical pathways involved in cellular growth and immune response modulation. This compound is studied for its potential applications in pharmacology due to its various biological activities. Researchers have explored its roles in antimicrobial, anti-inflammatory, and potential anticancer activities. Its mode of action often involves the inhibition of specific enzymes or the modulation of signal transduction pathways that are important for the proliferation of cells. Marmesinin is of particular interest in the development of novel therapeutic agents and understanding plant-derived compounds' structure-activity relationship. Its applications in scientific research extend to biochemistry and pharmacognosy, where it is used to elucidate the potential of natural products in medicine.

4-Methyl-6-Methoxycoumarin is a natural product isolated from Eupatorium pauciflorum.

Ethyl coumarin-3-carboxylate, a coumarin derivative, serves as a pseudo-template for the synthesis of Molecularly Imprinted Polymers (MIPs) that specifically

Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the