Coumarins

Lactone

Fraxin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Salvianolic acid A has antioxidant, hepatoprotective, antithrombotic effect, and antiplatelet actions. it also has a significant protective effect against isoproterenol-induced myocardial infarction; it activates the Nrf2/HO-1 axis in RPE cells and protects against oxidative stress via activation of Akt/mTORC1 signaling. Salvianolic acid A (oral) can significantly improve glucose metabolism and inhibit oxidative injury as well as protect against impaired vascular responsiveness in STZ-induced diabetic rats. It is a novel matrix metalloproteinase-9 inhibitor, can prevents cardiac remodeling in spontaneously hypertensive rats.

Osthol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Daphnetin-8-glucoside is a natural phenolic glucoside compound derived from plants of the Thymelaeaceae family, specifically from the Daphne genus. This compound is produced by the glycosylation of daphnetin, a coumarin derivative found in various botanical sources. The glycoside linkage enhances its solubility and stability, facilitating its bioavailability. Daphnetin-8-glucoside exhibits potent antioxidant and anti-inflammatory activities, mediated through the scavenging of free radicals and inhibition of pro-inflammatory cytokine production. Additionally, it modulates signal transduction pathways involved in cellular oxidative stress responses. In scientific research, Daphnetin-8-glucoside is used for its potential therapeutic effects in managing oxidative stress-related disorders and inflammatory conditions. Its biological activities make it a candidate for investigating new therapeutic avenues in neurodegenerative diseases, cardiovascular health, and skin protection. Researchers explore its efficacy and mechanism of action to understand its role in cellular protection and its potential integration into clinical applications. The study of such natural compounds contributes to the broader understanding of plant-derived bioactives and their impact on human health.