Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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NVS-PAK1-1
CAS:NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Formula:C23H25ClF3N5OPurity:99.35%Color and Shape:SolidMolecular weight:479.93Volociximab
CAS:Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.Purity:95%Color and Shape:Liquid2119738-71-3
CAS:Compound 2119738-71-3 interacts with the FAK receptor.Formula:C25H29ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:513.99AD57
CAS:AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.Formula:C22H20F3N7OPurity:98.23%Color and Shape:SoildMolecular weight:455.44Ref: TM-T22552L
1mg34.00€2mg52.00€5mg116.00€10mg212.00€25mg359.00€50mg512.00€100mg695.00€200mg939.00€1mL*10mM (DMSO)134.00€Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formula:C14H17N3O2SPurity:99.79% - 99.84%Color and Shape:SolidMolecular weight:291.37PKCη pseudosubstrate inhibitor,myristoylated
CAS:Myristoylated PKCη pseudosubstrate inhibitor is a cell-permeable compound utilized to investigate the mechanism of action of PKCη [1].Formula:C101H185N41O23SPurity:98%Color and Shape:SolidMolecular weight:2373.88Dynamin IN-2
CAS:Dynamin IN-2 (compound 43) is a Wiskostatin analogue.Formula:C22H21ClN2OPurity:98.81% - 98.83%Color and Shape:SoildMolecular weight:364.87Ref: TM-T64369
1mg140.00€5mg331.00€10mg439.00€25mg667.00€50mg894.00€100mg1,198.00€200mg1,596.00€1mL*10mM (DMSO)341.00€Ifebemtinib hydrochloride
Ifebemtinib (BI-853520) hydrochloride is a potent FAK (focal adhesion kinase) inhibitor with oral bioavailability, exhibiting an IC50 of 1 nM for recombinant FAK. Ifebemtinib hydrochloride demonstrates antiproliferative activity against cancer cells.Formula:C28H29ClF4N6O4Color and Shape:SolidMolecular weight:625.01Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56Compound 1T-0219 (SC)
CAS:Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620Formula:C20H19N3O7Purity:90%Color and Shape:SolidMolecular weight:413.38PF-AKT400
CAS:PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.Formula:C20H22F2N6OPurity:98.21%Color and Shape:SolidMolecular weight:400.43Ref: TM-T5508
1mg95.00€5mg227.00€10mg325.00€25mg550.00€50mg787.00€100mg1,093.00€1mL*10mM (DMSO)250.00€BIO-1211
CAS:BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Formula:C36H48N6O9Purity:99.33%Color and Shape:SolidMolecular weight:708.8D-ERYTHRO-SPHINGOSINE
CAS:D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activatorFormula:C18H37NO2Purity:98% - ≥98%Color and Shape:SolidMolecular weight:299.49Arimoclomol
CAS:Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Formula:C14H20ClN3O3Purity:99.81%Color and Shape:SolidMolecular weight:313.78Ref: TM-T13553
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)249.00€Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFormula:C26H44NNaO5SPurity:99.79% - 99.93%Color and Shape:SolidMolecular weight:505.69Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Color and Shape:LiquidMolecular weight:145.5 kDaBalamapimod
CAS:Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.Formula:C30H32ClN7OSPurity:98%Color and Shape:SolidMolecular weight:574.14AG1024
CAS:AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).Formula:C14H13BrN2OPurity:98% - 99.37%Color and Shape:SolidMolecular weight:305.17Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formula:C26H29N3O3Purity:99.43% - 99.67%Color and Shape:SolidMolecular weight:431.53Ref: TM-T6345
1mg35.00€5mg66.00€10mg81.00€25mg159.00€50mg280.00€100mg470.00€500mg1,035.00€1mL*10mM (DMSO)70.00€BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formula:C26H19Cl2N5O4Purity:98.87%Color and Shape:SolidMolecular weight:536.37Ref: TM-T14676
1mg183.00€5mg464.00€10mg655.00€25mg1,169.00€50mg1,539.00€100mg1,882.00€1mL*10mM (DMSO)547.00€AT-533
CAS:AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.Formula:C23H30N4O3Purity:99.54%Color and Shape:SoildMolecular weight:410.51Ref: TM-T67836
1mg51.00€5mg111.00€10mg170.00€25mg313.00€50mg467.00€100mg672.00€200mg905.00€1mL*10mM (DMSO)117.00€Azelaoyl PAF
CAS:Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.Formula:C33H66NO9PColor and Shape:SolidMolecular weight:651.85BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Formula:C27H24F5N5O3Purity:95.71% - 98.78%Color and Shape:SolidMolecular weight:561.5CIB-L43
CAS:CIB-L43 is an orally active TRBP inhibitor (KD = 4.78 nM) that disrupts the TRBP-dicer interaction (IC50 = 2.34 μM). It suppresses the biosynthesis of oncogenic miR-21, elevates PTEN and Smad7 expression, and inhibits AKT and TGF-β signaling, thereby reducing the proliferation and migration of HCC cells.Formula:C15H16N2O3SColor and Shape:SolidMolecular weight:304.364BCR-ABL-IN-8
CAS:BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].Formula:C30H33N7O5Purity:98%Color and Shape:SolidMolecular weight:571.63Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaVerbascoside
CAS:Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Formula:C29H36O15Purity:97.46% - 99.55%Color and Shape:SolidMolecular weight:624.59ML-B01
ML-B01 is an orally active inhibitor targeting Akt and PKA, with IC50 values of 2 nM and 136 nM, respectively. It demonstrates good blood-brain barrier (BBB) permeability in mice.Formula:C24H31Cl2N5OColor and Shape:SolidMolecular weight:476.44MSN-125
CAS:MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.Formula:C36H38BrN3O6Purity:98%Color and Shape:SolidMolecular weight:688.61Dihydrocytochalasin B
CAS:Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.Formula:C29H39NO5Purity:98%Color and Shape:SolidMolecular weight:481.62Ipatasertib
CAS:Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Formula:C24H32ClN5O2Purity:98.28% - 99.21%Color and Shape:SolidMolecular weight:458αVβ8-IN-1
CAS:αVβ8-IN-1 is an inhibitor of the αVβ8 integrin. It exhibits growth-suppressive activity against tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 is suitable for research related to idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia (NSIP), and various cancers.Formula:C25H32ClN5O4Color and Shape:SolidMolecular weight:502.01FRAX486 HCL(1232030-35-1 free base)
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Formula:C25H24Cl3FN6OPurity:98.85% - 99.82%Color and Shape:SolidMolecular weight:549.86Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Color and Shape:Odour LiquidPF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Formula:C26H34F3N5O7SPurity:99% - 99.46%Color and Shape:SolidMolecular weight:617.63Ref: TM-T4342
1mg78.00€2mg100.00€5mg159.00€10mg288.00€25mg419.00€50mg615.00€100mg878.00€500mg1,776.00€1mL*10mM (DMSO)233.00€TCS 21311
CAS:TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Formula:C27H25F3N4O4Purity:≥98%Color and Shape:SolidMolecular weight:526.51Bimosiamose
CAS:Bimosiamose has anti-inflammatory effects[1].Formula:C46H54O16Purity:98%Color and Shape:SolidMolecular weight:862.91αvβ1 integrin-IN-1
CAS:αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Formula:C26H34N6O6SPurity:100% - 99.74%Color and Shape:SolidMolecular weight:558.65Ref: TM-T13473
1mg115.00€5mg274.00€10mg432.00€25mg697.00€50mg938.00€100mg1,293.00€200mg1,738.00€1mL*10mM (DMSO)349.00€Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formula:C29H41F3N8O9Color and Shape:SolidMolecular weight:702.68DB07107
CAS:DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).Formula:C23H22N4OPurity:98%Color and Shape:SolidMolecular weight:370.45Estramustine
CAS:Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.Formula:C23H31Cl2NO3Purity:98.09%Color and Shape:SolidMolecular weight:440.4Ref: TM-T20681
5mg47.00€10mg70.00€25mg126.00€50mg202.00€100mg329.00€200mg487.00€1mL*10mM (DMSO)50.00€Lifitegrast sodium
CAS:Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Formula:C29H23Cl2N2NaO7SPurity:99.33%Color and Shape:SolidMolecular weight:637.46Ro 31-8220 Mesylate
CAS:Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.Formula:C25H23N5O2S·CH4O3SPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:553.65Ref: TM-T6643
1mg52.00€2mg67.00€5mg97.00€10mg159.00€25mg244.00€50mg338.00€100mg500.00€1mL*10mM (DMSO)140.00€Blinatumomab
CAS:Blinatumomab (AMG-10,MT-103) is a CD19/CD3 bispecific B-cell and T-cell binding antibody that in acute lymphoblastic leukemia and non-Hodgkin's lymphoma.Color and Shape:LiquidPironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formula:C19H32O4Purity:98%Color and Shape:SolidMolecular weight:324.45ALK inhibitor 2
CAS:ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.Formula:C23H28ClN7O3SPurity:99% - 99.77%Color and Shape:SolidMolecular weight:518.03HS-27
CAS:HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.Formula:C52H60N6O12SPurity:97.09%Color and Shape:SolidMolecular weight:993.13Ref: TM-T18018
1mg90.00€5mg215.00€10mg344.00€25mg612.00€50mg848.00€100mg1,159.00€1mL*10mM (DMSO)378.00€Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purity:95% - 99.19%Color and Shape:Yellow To Orange SolidMolecular weight:383.83Bosutinib hydrate
CAS:Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.Formula:C26H31Cl2N5O4Purity:99.87%Color and Shape:SolidMolecular weight:548.46Synstatin (92-119)
CAS:Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFormula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Formula:C29H37N7O5SPurity:100% - 99.70%Color and Shape:SolidMolecular weight:595.71PAK4-IN-3
PAK4-IN-3 (compound 27e) is a PAK4 inhibitor exhibiting an IC50 of 10 nM and demonstrates antiproliferative effects on A549 cells with an IC50 of 0.61μM.Purity:98%Color and Shape:Odour SolidAurothiomalate sodium
CAS:Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Formula:C4H3AuNa2O4SPurity:99.66%Color and Shape:SoildMolecular weight:390.07Capivasertib
CAS:Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.Formula:C21H25ClN6O2Purity:97.59% - 99.6%Color and Shape:SolidMolecular weight:428.92Ref: TM-T1920
1mg40.00€2mg52.00€5mg70.00€10mg99.00€25mg168.00€50mg246.00€100mg378.00€200mg610.00€1mL*10mM (DMSO)89.00€Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Formula:C24H31N3O3Purity:98.05% - 99.82%Color and Shape:SolidMolecular weight:409.52Norathyriol
CAS:Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.Formula:C13H8O6Purity:98.90% - 98.93%Color and Shape:SolidMolecular weight:260.2Ref: TM-TN1990
1mg149.00€5mg354.00€10mg528.00€25mg852.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)522.00€α7β1 integrin modulator-1
CAS:α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].Formula:C23H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:475.56AS2521780
CAS:AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).Formula:C30H41N7OSPurity:98%Color and Shape:SolidMolecular weight:547.76Dasatinib hydrochloride
CAS:Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).Formula:C22H27Cl2N7O2SPurity:99.88% - 99.98%Color and Shape:SolidMolecular weight:524.47Pep2m, myristoylated acetate
Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.Formula:C65H122N18O16SPurity:99.62%Color and Shape:SolidMolecular weight:1443.96PKC 20-28,myristoylated
Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1].Formula:C60H106N18O11Purity:98%Color and Shape:SolidMolecular weight:1255.6CMPD101
CAS:CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formula:C24H21F3N6OPurity:98.34% - 99.01%Color and Shape:SolidMolecular weight:466.46TPPB
CAS:TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).Formula:C27H30F3N3O3Purity:98.00%Color and Shape:SolidMolecular weight:501.54DCP-LA
CAS:DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.Formula:C20H36O2Purity:98%Color and Shape:SolidMolecular weight:308.5Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Color and Shape:LiquidEgaptivon pegol
CAS:Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) with platelet GPIb receptors, exhibiting anti-thromboticPurity:98%Color and Shape:LiquidKinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Formula:C20H16Br2N4O4Purity:97.24%Color and Shape:SolidMolecular weight:536.17Ref: TM-T15663
2mg43.00€5mg66.00€10mg94.00€25mg159.00€50mg230.00€100mg346.00€200mg520.00€1mL*10mM (DMSO)74.00€Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.Formula:C19H34N8O11Purity:99.81%Color and Shape:SolidMolecular weight:550.52(R)-Fangchinoline
CAS:(R)-Fangchinoline ((+)-Thalrugosine) is extracted from Stephania tetrandra S. Moore.Formula:C37H40N2O6Purity:98% - 99.72%Color and Shape:SolidMolecular weight:608.72Protein Kinase C (19-31)
CAS:Protein Kinase C (19-31), a PKC inhibitor derived from PKCa, has a serine at position 25 and tests PKC activity.Formula:C67H118N26O16Purity:98%Color and Shape:Lyophilized PowderMolecular weight:1543.82Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurity:99.25%Color and Shape:SolidMolecular weight:537.63Ref: TM-T16130
2mg42.00€5mg64.00€10mg92.00€25mg170.00€50mg311.00€100mg449.00€200mg630.00€1mL*10mM (DMSO)74.00€Antitumor agent-86
CAS:Antitumor agent-86 targets MCF-7 cells with 2.62 µM IC50, induces apoptosis, and disrupts RAS/PI3K/Akt/JNK pathways.Formula:C29H31N5O2SPurity:98%Color and Shape:SolidMolecular weight:513.65[Ala107]-MBP (104-118) acetate
[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP).Formula:C59H108N20O21Purity:99.23%Color and Shape:SolidMolecular weight:1553.72Myosin V-IN-1
CAS:Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.Formula:C29H26N6O3SPurity:97.31% - 97.31%Color and Shape:SolidMolecular weight:538.62Ref: TM-T72060
1mg314.00€5mg663.00€10mg944.00€25mg1,396.00€50mg1,890.00€100mg2,547.00€1mL*10mM (DMSO)677.00€DPH
CAS:DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.Formula:C18H13FN4O2Purity:99.72%Color and Shape:SolidMolecular weight:336.32BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Formula:C24H30N8OPurity:99.37%Color and Shape:SolidMolecular weight:446.55AKT Kinase Inhibitor
CAS:AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.Cost-effective and quality-assured.Formula:C16H19N7O3Purity:98.53% - 99.86%Color and Shape:SolidMolecular weight:357.37Ref: TM-T10276
1mg136.00€5mg329.00€10mg567.00€25mg887.00€50mg1,188.00€100mg1,605.00€1mL*10mM (DMSO)360.00€CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Formula:C14H9N3OPurity:99.51%Color and Shape:SolidMolecular weight:235.24Ref: TM-T10704
1mg115.00€5mg274.00€10mg432.00€25mg845.00€50mg1,293.00€100mg1,768.00€1mL*10mM (DMSO)303.00€p5 Ligand for Dnak and DnaJ acetate
p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).Formula:C46H85N15O13SPurity:96.33%Color and Shape:SolidMolecular weight:1088.32DOTA-cyclo(RGDfK)
CAS:DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.Formula:C43H67N13O14Color and Shape:SoildMolecular weight:990.07Psychosine
CAS:Psychosine (Galactosylsphingosine) is a PKC inhibitor, and is highly cytotoxic, inducing cell death in a variety of cells.Formula:C24H47NO7Purity:98%Color and Shape:White PowderMolecular weight:461.63BI-1950
CAS:BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.Formula:C32H26Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:646.5KU-177
CAS:KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Formula:C27H23NO8Purity:97.34% - 98.54%Color and Shape:SolidMolecular weight:489.47KIF18A-IN-16
CAS:KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.Formula:C30H37N5O4SColor and Shape:SolidMolecular weight:563.71N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS:N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nMFormula:C24H18ClN3OPurity:98.65%Color and Shape:SoildMolecular weight:399.87Ref: TM-T60041
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€200mg1,454.00€1mL*10mM (DMSO)279.00€GNF-7
CAS:GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.Formula:C28H24F3N7O2Purity:97.05% - 99.47%Color and Shape:SolidMolecular weight:547.53(-)-Indolactam V
CAS:(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.Formula:C17H23N3O2Purity:98%Color and Shape:SolidMolecular weight:301.38ZINC194100678
CAS:ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.Formula:C10H13N5OPurity:98.3%Color and Shape:SolidMolecular weight:219.24Tau-aggregation and neuroinflammation-IN-1
CAS:Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.Formula:C25H20N2O7Purity:100%Color and Shape:SolidMolecular weight:460.44VER49009
CAS:VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).Formula:C19H18ClN3O4Purity:100% - 99.17%Color and Shape:SolidMolecular weight:387.82Ref: TM-T2268
1mg60.00€2mg85.00€5mg111.00€10mg167.00€25mg283.00€50mg472.00€100mg643.00€1mL*10mM (DMSO)96.00€HSDVHK-NH2 acetate
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).Formula:C32H52N12O11Purity:99.50%Color and Shape:SolidMolecular weight:780.39Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purity:99.21%Color and Shape:SolidMolecular weight:447.48FAK inhibitor 7
CAS:FAK inhibitor7, a potent FAK inhibitor, demonstrates an IC50 of 3.58 nM. This compound effectively inhibits downstream signaling cascades of FAK (such as Src and AKT), which leads to cell cycle arrest at the G0/G1 phase and induces cytotoxic autophagy in ovarian cancer cells. Additionally, FAK inhibitor7 has been shown to suppress tumor metastasis and growth in ovarian cancer mouse models.Formula:C32H37N7O3Color and Shape:SolidMolecular weight:567.68ALK-IN-29
ALK-IN-29 (compound 4c) exhibits inhibitory effects on tyrosine protein kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, displaying a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is applicable in cancer research.Formula:C29H32FN3OColor and Shape:SolidMolecular weight:457.58MPT0B014
CAS:MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.Formula:C19H17NO4Purity:99.56%Color and Shape:SolidMolecular weight:323.34PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48KU-32
CAS:KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.Formula:C20H25NO8Purity:98%Color and Shape:SolidMolecular weight:407.41iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formula:C35H57N13O14S2Purity:98.77%Color and Shape:SolidMolecular weight:948.04S-methyl DM1
CAS:S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Formula:C36H50ClN3O10SPurity:98%Color and Shape:SolidMolecular weight:752.31HSP90-IN-22
CAS:HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM inFormula:C25H30N4O3Purity:98%Color and Shape:SolidMolecular weight:434.53
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