Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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Cenisertib
CAS:Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as wellFormula:C24H30FN7OColor and Shape:SolidMolecular weight:451.54XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ref: TM-T17267
1mg56.00€2mg78.00€5mg99.00€10mg149.00€25mg258.00€50mg393.00€100mg582.00€1mL*10mM (DMSO)110.00€Bisindolylmaleimide VIII acetate
CAS:Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Formula:C26H26N4O4Purity:99.27%Color and Shape:SolidMolecular weight:458.51PKC-ε translocation inhibitor peptide
PKC-ε Translocation Inhibitor Peptide is a selective modulator that controls the FcγR-mediated internalization rate of opsonized beads without affecting FcαRPurity:98%Color and Shape:Odour SolidArg-Gly-Asp TFA (99896-85-2(free base))
Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.Formula:C14H23F3N6O8Purity:99.2% - ≥98%Color and Shape:SolidMolecular weight:460.36STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Purity:95% - 95%Color and Shape:Odour LiquidEMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Formula:C25H31F3N4O2Purity:98%Color and Shape:SolidMolecular weight:476.53Nilotinib monohydrochloride monohydrate
CAS:Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosineFormula:C28H22F3N7O·HCl·H2OPurity:99.93%Color and Shape:SolidMolecular weight:583.99Anti-Mouse IL-1a Antibody (ALF-161)
Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.Purity:98%Color and Shape:Odour SolidDanicamtiv
CAS:Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Formula:C16H20F3N5O4SPurity:99.38%Color and Shape:SolidMolecular weight:435.42Ref: TM-T15050
1mg136.00€5mg274.00€10mg454.00€25mg750.00€50mg1,026.00€100mg1,406.00€1mL*10mM (DMSO)303.00€LY 379196
LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.Formula:C30H34N4O5SColor and Shape:SolidMolecular weight:562.68XL888
CAS:XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.Formula:C29H37N5O3Purity:98.1%Color and Shape:SolidMolecular weight:503.64Loureirin A
CAS:Loureirin A inhibits platelet aggregation and PI3K/Akt signaling, promotes hair follicle repair, and has anti-fibrotic and anti-angiogenic properties.Formula:C17H18O4Purity:99.83% - 99.84%Color and Shape:SolidMolecular weight:286.32Ref: TM-T5S0896
1mg74.00€5mg133.00€10mg188.00€25mg329.00€50mg490.00€100mg697.00€200mg938.00€1mL*10mM (DMSO)207.00€Mitoxantrone
CAS:Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Formula:C22H28N4O6Purity:97.97% - 98.74%Color and Shape:Blue PowderMolecular weight:444.48CID-663143
CAS:CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.Formula:C19H18N4O2SPurity:99.56% - 99.68%Color and Shape:SolidMolecular weight:366.44Ref: TM-T23889
1mg77.00€5mg158.00€10mg225.00€25mg338.00€50mg475.00€100mg638.00€200mg845.00€1mL*10mM (DMSO)164.00€Soblidotin
CAS:Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.Formula:C39H67N5O6Purity:97.48%Color and Shape:SolidMolecular weight:701.98DCPLA-ME
CAS:DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerativeFormula:C21H38O2Purity:98.16%Color and Shape:SolidMolecular weight:322.53Ref: TM-T10980
1mg65.00€5mg133.00€10mg180.00€25mg369.00€50mg605.00€100mg815.00€200mg1,111.00€1mL*10mM (DMSO)145.00€MT189
CAS:MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.Formula:C21H18FN3O2Purity:98.67%Color and Shape:SoildMolecular weight:363.38G-5555 hydrochloride (1648863-90-4 free base)
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.Formula:C25H26Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:529.42TAS0612
CAS:TAS0612, a novel oral inhibitor of RSK, AKT, and S6K, exhibits broad-spectrum antitumor activity by impeding cell growth [1].Formula:C27H34F3N9O2Purity:98%Color and Shape:SolidMolecular weight:573.61Recilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Formula:C16H13ClO4SPurity:98.85% - 98.96%Color and Shape:SolidMolecular weight:336.79Ref: TM-T13862
1mg46.00€2mg59.00€5mg87.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)105.00€LP-261
CAS:LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.Formula:C22H19N3O4SPurity:99.76%Color and Shape:SolidMolecular weight:421.47Ref: TM-T9595
1mg38.00€2mg49.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€1mL*10mM (DMSO)87.00€Sabizabulin
CAS:Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.Formula:C21H19N3O4Purity:98.04% - 99.76%Color and Shape:SolidMolecular weight:377.39Ref: TM-T17228
1mg145.00€2mg207.00€5mg354.00€10mg547.00€25mg880.00€50mg1,198.00€100mg1,596.00€500mg3,220.00€KOdiA-PC
CAS:KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.Formula:C32H58NO11PColor and Shape:SolidMolecular weight:663.78PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Purity:95.01%Color and Shape:SoildMps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Formula:C26H36N6O3Purity:96.24% - 99.75%Color and Shape:SolidMolecular weight:480.6Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:SolidMolecular weight:438.48Ref: TM-T6278
1mg49.00€5mg96.00€10mg166.00€25mg313.00€50mg553.00€100mg790.00€500mg1,578.00€1mL*10mM (DMSO)115.00€K-80003
CAS:K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.Formula:C22H21FO2Purity:99.76%Color and Shape:SolidMolecular weight:336.4Ref: TM-T11734
1mg49.00€5mg104.00€10mg166.00€25mg283.00€50mg430.00€100mg633.00€500mg1,349.00€1mL*10mM (DMSO)115.00€Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Formula:C27H36N6O3Purity:99.53%Color and Shape:SolidMolecular weight:492.61Rotigaptide TFA(355151-12-1 free base)
Rotigaptide TFA is a Cx43 modulator & AAP that maintains gap junctions & cell communication under stress.Formula:C30H40F3N7O11Purity:99.21%Color and Shape:SolidMolecular weight:731.67PROTAC Hsp90α degrader 1
Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and is utilized in breast cancer research.Formula:C43H50N6O7Purity:98%Color and Shape:SolidMolecular weight:762.89PF-562271 besylate
CAS:PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formula:C21H20F3N7O3S·C6H6O3SPurity:97.65% - 99.01%Color and Shape:SolidMolecular weight:665.66Ref: TM-T6177
1mg38.00€5mg79.00€10mg88.00€25mg145.00€50mg210.00€100mg313.00€200mg452.00€1mL*10mM (DMSO)95.00€Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Purity:SDS-PAGE:95% SEC-HPLC:98.77%Color and Shape:LiquidMolecular weight:146.14 kDaAntiangiogenic agent 4
Compound 3b, an antiangiogenic agent, inhibits Akt phosphorylation in both HFF and HUVEC cells and is utilized in cancer research [1].Formula:C21H24N4O3Purity:98%Color and Shape:SolidMolecular weight:380.44NAP1051
CAS:NAP1051, a biomimetic analog of Lipoxin A4, serves an anti-tumor role by targeting the inflammatory tumor microenvironment. It inhibits the chemotaxis of neutrophils to fMLP and stimulates macrophage efferocytosis by activating AKT. NAP1051 is utilized in research on colorectal cancer.Formula:C23H34O5Color and Shape:SolidMolecular weight:390.51YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formula:C21H22ClFN2OPurity:99.65%Color and Shape:SolidMolecular weight:372.86FAK-IN-10
CAS:FAK-IN-10 is an inhibitor of FAK (IC50:76.3 μM).FAK-IN-10 z MCF-7 and A431 cell lines showed antitumor activity with IC50 of 4.23 and 0.78 μM, respectively.Formula:C15H10BrN3O2SPurity:99.78%Color and Shape:SoildMolecular weight:376.23FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro
CAS:FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro, also known as FITC-linked GRGDSP, is a fluorescent peptide with integrin inhibitory properties.Formula:C49H59N11O16SPurity:98%Color and Shape:SolidMolecular weight:1090.12Vodobatinib
CAS:Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.Formula:C27H20ClN3O2Purity:99.06% - 99.55%Color and Shape:SolidMolecular weight:453.92Ref: TM-T8882
1mg37.00€5mg79.00€10mg116.00€25mg212.00€50mg340.00€100mg528.00€500mg1,275.00€1mL*10mM (DMSO)87.00€Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFormula:C184H284N52O57S8·3C2H4O2Purity:99.51%Color and Shape:SolidMolecular weight:4573.21KW-2478
CAS:KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.Formula:C30H42N2O9Purity:98.68% - 99.52%Color and Shape:SolidMolecular weight:574.66Ref: TM-T6558
1mg56.00€2mg81.00€5mg119.00€10mg187.00€25mg316.00€50mg472.00€100mg662.00€1mL*10mM (DMSO)205.00€Mavacamten
CAS:Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)Formula:C15H19N3O2Purity:99.53% - 99.98%Color and Shape:SolidMolecular weight:273.33[Ala113]-MBP (104-118) acetate
[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.Formula:C69H108N20O21Purity:97.72%Color and Shape:SolidMolecular weight:1553.74Gypsogenin
CAS:Gypsogenin (639-14-5) is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.Formula:C30H46O4Purity:99.73%Color and Shape:SolidMolecular weight:470.68Ref: TM-T25476
1mg134.00€5mg315.00€10mg469.00€25mg748.00€50mg1,064.00€100mg1,415.00€1mL*10mM (DMSO)349.00€Tubulin inhibitor 7
CAS:Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (Formula:C21H14N2O4Purity:98%Color and Shape:SolidMolecular weight:358.35ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Formula:C15H11BrN2O2SPurity:99.34%Color and Shape:SolidMolecular weight:363.23Ref: TM-T13147
1mg185.00€5mg393.00€10mg587.00€25mg935.00€50mg1,264.00€100mg1,700.00€500mg3,410.00€1mL*10mM (DMSO)432.00€Benproperine phosphate
CAS:Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.Formula:C21H30NO5PPurity:99.84%Color and Shape:PowderMolecular weight:407.44Bimosiamose disodium
CAS:Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.Formula:C46H52Na2O16Purity:98%Color and Shape:SolidMolecular weight:906.88IPA-3
CAS:IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).Formula:C20H14O2S2Purity:96.7%Color and Shape:SolidMolecular weight:350.45Peptide5 TFA
Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury.Formula:C62H99F3N16O22SPurity:98%Color and Shape:SolidMolecular weight:1509.6α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Formula:C16H26N4O11Purity:98.46%Color and Shape:SolidMolecular weight:450.4Larixol
CAS:Larixol acts as both an fMLP inhibitor and a modulator of various signaling pathways by inhibiting Src kinase, ERK1/2, p38, and AKT phosphorylation critical forFormula:C20H34O2Purity:98%Color and Shape:SolidMolecular weight:306.48BGG463
CAS:BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 μM, 0.09 μM and 0.590 μM, respectively.Formula:C30H29F3N6O3Purity:100% - 95.05%Color and Shape:SolidMolecular weight:578.58Ref: TM-T4618
1mg62.00€2mg87.00€5mg119.00€10mg188.00€25mg350.00€50mg505.00€100mg730.00€1mL*10mM (DMSO)154.00€Protein Kinase C (19-31) (TFA)(121545-65-1,free)
Protein Kinase C (19-31) TFA is a serine-modified PKCa-derived inhibitor for testing PKC activity.Formula:C69H119F3N26O18Purity:98%Color and Shape:SolidMolecular weight:1657.842',4'-DIHYDROXYCHALCONE
CAS:2',4'-DIHYDROXYCHALCONE (2',4'-DHC) as a compound with Hsp90 inhibitory and antifungal effectsFormula:C15H12O3Purity:98.95%Color and Shape:SolidMolecular weight:240.25Ref: TM-T8829
2mg42.00€5mg62.00€10mg87.00€25mg154.00€50mg235.00€100mg354.00€200mg520.00€1mL*10mM (DMSO)65.00€Triclabendazole
CAS:Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.Formula:C14H9Cl3N2OSPurity:99.11%Color and Shape:White To Brown Crystalline PowderMolecular weight:359.66Tubulin inhibitor 24
CAS:Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Formula:C22H21N3O3Purity:99.89%Color and Shape:SolidMolecular weight:375.42Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Formula:C29H31NO7Purity:95.32% - 98.46%Color and Shape:SolidMolecular weight:505.56mP6
CAS:mP6 (Myr-FEEERA-OH), a myristoylated peptide, selectively inhibits Gα 13's interaction with integrin β 3 while preserving talin-dependent integrin function.Formula:C47H75N9O14Purity:98%Color and Shape:SolidMolecular weight:990.15HG-7-86-01
CAS:HG-7-86-01 is a selective type II tyrosine kinase inhibitor with antiproliferative activity against mutant T315I- Bcr-Abl for chronic myeloid leukemia (CML).Formula:C28H21F3N6O2SPurity:99.07%Color and Shape:SolidMolecular weight:562.57Bisindolylmaleimide V
CAS:Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.Formula:C21H15N3O2Purity:90%Color and Shape:Red SolidMolecular weight:341.36Verubulin
CAS:Verubulin (MPC 6827) is a microtubule blocking agent with cytotoxic and potentially anticancer activity that disrupts newly formed blood vessels in xenografts.Formula:C17H17N3OPurity:99.98%Color and Shape:SolidMolecular weight:279.34UMK57
CAS:UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Formula:C17H17N3SPurity:99.81%Color and Shape:SolidMolecular weight:295.4Thiabendazole
CAS:Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.Formula:C10H7N3SPurity:99.14%Color and Shape:Light Yellow PowderMolecular weight:201.25PKCβII Peptide Inhibitor I
CAS:PKCβII Peptide Inhibitor I, a specific PKCβII inhibitor, exhibits cardioprotective properties in a rat cardiac ischemia/reperfusion injury model and mitigatesFormula:C61H94N12O19Purity:98%Color and Shape:SolidMolecular weight:1299.47EL-102
CAS:EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.Formula:C19H16N2O3S2Purity:99.34%Color and Shape:SolidMolecular weight:384.47Ref: TM-T15205
1mg87.00€5mg216.00€10mg349.00€25mg545.00€50mg740.00€100mg1,103.00€1mL*10mM (DMSO)183.00€AG957
CAS:Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling inFormula:C15H15NO4Purity:98.82%Color and Shape:SolidMolecular weight:273.28Ref: TM-T21785
1mg89.00€5mg212.00€10mg315.00€25mg527.00€50mg750.00€100mg1,017.00€1mL*10mM (DMSO)265.00€Adaphostin
CAS:Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.Formula:C24H27NO4Purity:97.31%Color and Shape:SolidMolecular weight:393.48Vaccarin
CAS:Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.Formula:C32H38O19Purity:99.16% - 99.97%Color and Shape:SolidMolecular weight:726.63GSK-923295
CAS:GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Formula:C32H38ClN5O4Purity:96.22% - 98.02%Color and Shape:SolidMolecular weight:592.13Ref: TM-T2039
1mg49.00€2mg70.00€5mg97.00€10mg168.00€25mg331.00€50mg510.00€100mg737.00€1mL*10mM (DMSO)136.00€Mitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Formula:C22H30Cl2N4O6Purity:100% - 99.85%Color and Shape:Blue-Black Solid From Water Ethanol SolidMolecular weight:517.4Feretoside
CAS:Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).Formula:C17H24O11Purity:99.15%Color and Shape:SolidMolecular weight:404.37Ref: TM-TQ0280
1mg85.00€5mg180.00€10mg274.00€25mg465.00€50mg663.00€100mg919.00€500mg1,833.00€1mL*10mM (DMSO)298.00€Ombrabulin
CAS:Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.Formula:C21H26N2O6Purity:98%Color and Shape:SolidMolecular weight:402.44GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Formula:C20H11Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:400.2117-AEP-GA
CAS:17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.Formula:C34H50N4O8Purity:97.77% - 99.56%Color and Shape:SolidMolecular weight:642.78Tirofiban hydrochloride monohydrate
CAS:Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.Formula:C22H39ClN2O6SPurity:95.83% - 99.94%Color and Shape:White SolidMolecular weight:495.07Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFormula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24Ref: TM-TN1299
1mg178.00€5mg540.00€10mg715.00€25mg1,103.00€50mg1,491.00€100mg2,005.00€500mg4,010.00€1mL*10mM (DMSO)442.00€PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Formula:C29H36ClN5O4Purity:98%Color and Shape:SolidMolecular weight:554.08PKCβ inhibitor 1
CAS:PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,Formula:C24H21N5O2Purity:99.33%Color and Shape:SolidMolecular weight:411.46Ref: TM-T8376
1mg154.00€5mg424.00€10mg605.00€25mg920.00€50mg1,216.00€100mg1,673.00€200mg2,252.00€500µg93.00€1mL*10mM (DMSO)401.00€Ingenol
CAS:Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.Formula:C20H28O5Purity:99.78% - 99.87%Color and Shape:SolidMolecular weight:348.43Ref: TM-T5S2017
1mg52.00€5mg95.00€10mg127.00€25mg246.00€50mg467.00€100mg640.00€500mg1,359.00€1mL*10mM (DMSO)96.00€PF04929113
CAS:PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.Formula:C25H30F3N5O4Purity:99.06%Color and Shape:SolidMolecular weight:521.53Ref: TM-T6341
1mg39.00€2mg49.00€5mg84.00€10mg119.00€25mg187.00€50mg354.00€100mg527.00€1mL*10mM (DMSO)96.00€OXA-11
CAS:OXA-11 (FAK-IN-16) is a FAK inhibitor with anti-tumor activity, useful for cancer research.Formula:C37H49F3N7O5PPurity:98.70% - 99.20%Color and Shape:SolidMolecular weight:759.8cSRC/BCR-ABL1-IN-1
cSRC/BCR-ABL1-IN-1 (compound 16a) is a dual-target inhibitor of the cSRC/BCR-ABL1 kinases.Formula:C24H27ClN6O4Color and Shape:SolidMolecular weight:498.96HSP90-IN-19
CAS:HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.Formula:C29H38O7Purity:98%Color and Shape:SolidMolecular weight:498.61ATM-3507
CAS:ATM-3507 is an inhibitor of tropomyosin. In human melanoma cell lines, the IC50s are from 3.83-6.84 μM.Formula:C37H46FN5O2Purity:96.36% - 99.10%Color and Shape:SolidMolecular weight:611.79Asciminib
CAS:Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5-0.8nM).Formula:C20H18ClF2N5O3Purity:97.93% - 99.45%Color and Shape:SolidMolecular weight:449.84Ref: TM-T5177
1mg63.00€2mg92.00€5mg127.00€10mg187.00€25mg305.00€50mg427.00€100mg630.00€500mg1,320.00€1mL*10mM (DMSO)139.00€Natalizumab
CAS:Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Purity:98.00%Color and Shape:LiquidMolecular weight:N/AHSP90-IN-32
CAS:HSP90-IN-32, a carboxy-terminus inhibitor of Hsp90C, exhibits antiproliferative activity in various cell lines including SKMel173, SKMel103, SKMel19, and A375, with IC50 values of 1.01 μM, 0.782 μM, 0.607 μM, and 1.413 μM, respectively. This compound holds potential for research in anticancer agents.Formula:C33H40N2O4Color and Shape:SolidMolecular weight:528.68CW-069
CAS:CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Formula:C23H21IN2O3Purity:97.52% - 98.59%Color and Shape:SolidMolecular weight:500.33Ref: TM-T6209
1mg43.00€5mg90.00€10mg125.00€25mg216.00€50mg306.00€100mg432.00€500mg938.00€1mL*10mM (DMSO)89.00€DM4
CAS:DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.Formula:C38H54ClN3O10SPurity:98.15%Color and Shape:SolidMolecular weight:780.37NQTrp
CAS:NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.Formula:C21H16N2O4Purity:98%Color and Shape:SolidMolecular weight:360.36N-Phenylbenzylamine
CAS:A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerizationFormula:C13H13NPurity:99.93%Color and Shape:Colorless To Pale Yellow Crystalline PowderMolecular weight:183.25Curvulin
CAS:Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.Formula:C12H14O5Purity:98.97%Color and Shape:SolidMolecular weight:238.24Ref: TM-T36850
1mg145.00€5mg319.00€10mg472.00€25mg753.00€50mg1,074.00€100mg1,444.00€1mL*10mM (DMSO)284.00€Hu7691 free base
CAS:Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.Formula:C22H21F3N4OPurity:98.89%Color and Shape:SolidMolecular weight:414.423H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formula:C23H38N10O10Purity:100%Color and Shape:SolidMolecular weight:614.61Phenamacril
CAS:Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.Formula:C12H12N2O2Purity:99.37%Color and Shape:SolidMolecular weight:216.24Ref: TM-T24214
1mg145.00€5mg319.00€10mg472.00€25mg753.00€50mg1,074.00€100mg1,444.00€500mg2,822.00€1mL*10mM (DMSO)274.00€α-Linolenic acid
CAS:α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and lowers blood lipids. Cost-effective and quality-assured.Formula:C18H30O2Purity:98.19% - 99.81%Color and Shape:Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:278.43Cyclo(RGDfC) TFA
Zelminemab (AMG-301) is a humanized monoclonal antibody targeting ADCYAP1R1 for use in neurological disorders.Formula:C26H35F3N8O9SPurity:98.59%Color and Shape:SolidMolecular weight:692.67ɛPKC(85-92),Myristoylated
CAS:PKC(85-92),Myristoylated is a myristic acid-conjugated, cell-permeable peptide activator of PKC that has been shown to increase nitric oxide (NO) release inFormula:C53H80N10O15Purity:98%Color and Shape:SolidMolecular weight:1097.26cRGDfK-thioacetyl ester
CAS:cRGDfK-thioacetyl ester, a bioactive polypeptide, exhibits selective affinity for integrins and can modify near-infrared (NIR) fluorescent probes for targetedFormula:C31H45N9O9SPurity:98%Color and Shape:SolidMolecular weight:719.81
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