Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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VER-49009
CAS:VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).Formula:C19H18ClN3O4Purity:99.36% - 99.99%Color and Shape:SolidMolecular weight:387.82Ref: TM-T3454
2mg46.00€5mg64.00€10mg92.00€25mg164.00€50mg259.00€100mg354.00€200mg500.00€1mL*10mM (DMSO)52.00€GW406108X(Z/E)
CAS:GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .Formula:C20H11Cl2NO4Purity:98.23%Color and Shape:SolidMolecular weight:400.21Ref: TM-T9207L
1mg131.00€5mg286.00€10mg430.00€25mg647.00€50mg969.00€100mg1,301.00€1mL*10mM (DMSO)283.00€Valrubicin
CAS:Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Formula:C34H36F3NO13Purity:98.63%Color and Shape:SolidMolecular weight:723.64Tubulin inhibitor 8
CAS:Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.Formula:C21H14N2O3Purity:100% - 99.34%Color and Shape:SolidMolecular weight:342.35TTBK1-IN-2
CAS:TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.Formula:C18H13ClN4OPurity:99.83%Color and Shape:SoildMolecular weight:336.77Ref: TM-T60086
1mg81.00€5mg168.00€10mg240.00€25mg399.00€50mg567.00€100mg758.00€200mg1,017.00€1mL*10mM (DMSO)170.00€Pimitespib
CAS:Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).Formula:C25H26N8OPurity:99.22% - 99.49%Color and Shape:SolidMolecular weight:454.53P8RI acetate
P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.Formula:C53H81N13O11Purity:99.61%Color and Shape:SolidMolecular weight:1076.29Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formula:C16H11N3Purity:99.69%Color and Shape:SolidMolecular weight:245.28Ref: TM-T12359
5mg48.00€10mg62.00€25mg97.00€50mg169.00€100mg250.00€200mg373.00€500mg612.00€1mL*10mM (DMSO)52.00€DDO-5936
CAS:DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.Formula:C25H29N5O4SPurity:99.81%Color and Shape:SolidMolecular weight:495.59Ref: TM-T9202
1mg37.00€5mg80.00€10mg126.00€25mg264.00€50mg389.00€100mg553.00€200mg750.00€1mL*10mM (DMSO)88.00€22-(4′-py)-JA
CAS:22-(4′-py)-JA, a semisynthetic derivative of junamycin A isolated from the Thai blue sponge (Xestospongia sp.), exhibits antimetastatic properties by inhibitingFormula:C32H30N4O8Purity:98%Color and Shape:SolidMolecular weight:598.6Kif15-IN-1
CAS:Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Formula:C20H22N4O5SPurity:99.39% - 99.39%Color and Shape:SolidMolecular weight:430.48TC-Mps1-12
CAS:TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .Formula:C17H20N6OPurity:98%Color and Shape:SolidMolecular weight:324.38GSK215
CAS:GSK215: potent, selective PROTAC degrader of FAK (pDC50=8.4), combines FAK inhibitor VS-4718 and VHL E3 ligase binder, causes fast, lasting FAK degradation.Formula:C50H59F3N10O6SPurity:99.3%Color and Shape:SoildMolecular weight:985.13Dioleyl phosphatidylserine
CAS:Dioleyl phosphatidylserine is a phospholipid that can activate PKC-γ (Protein Kinase C-gamma) when the Ca2+ concentration is below 0.5 μM, specifically at a concentration of 100 μM.Formula:C42H78NO10PColor and Shape:SolidMolecular weight:788.04Flumatinib mesylate
CAS:Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Formula:C30H33F3N8O4SPurity:99.82%Color and Shape:SolidMolecular weight:658.69Ref: TM-T7861
1mg37.00€5mg88.00€10mg133.00€25mg250.00€50mg393.00€100mg628.00€500mg1,301.00€1mL*10mM (DMSO)139.00€NDNA4
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability.Formula:C31H35F3N2O5SPurity:98%Color and Shape:SolidMolecular weight:604.68Akt-I-1,2
CAS:Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.Formula:C23H22ClN3Purity:99.45%Color and Shape:SolidMolecular weight:375.89Ref: TM-T23695
1mg137.00€2mg180.00€5mg269.00€10mg395.00€25mg615.00€50mg832.00€100mg1,121.00€200mg1,510.00€Hu7691
CAS:Hu7691 is an Akt inhibitor that inhibits Akt1, Akt2, and Akt3, suppresses neuroblastoma cell proliferation, and induces differentiation of neuroblastoma cells.Formula:C22H22ClF3N4OPurity:99.86%Color and Shape:SolidMolecular weight:450.88Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Formula:C19H20O5Purity:100% - 97.22%Color and Shape:SolidMolecular weight:328.36Ref: TM-T3S1416
1mg43.00€5mg88.00€10mg119.00€25mg259.00€50mg462.00€100mg662.00€500mg1,359.00€1mL*10mM (DMSO)87.00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14GSK3335103
CAS:GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.Formula:C27H36FN3O4Color and Shape:SolidMolecular weight:485.59K34c hydrochloride
K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.Formula:C38H50ClN5O2Purity:100% - 99.95%Color and Shape:SoildMolecular weight:644.29Ref: TM-T41151L
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€1mL*10mM (DMSO)887.00€ATN-161 acetate
CAS:ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formula:C25H39N9O10SPurity:98.27%Color and Shape:SoildMolecular weight:657.7Ref: TM-T10398L
1mg201.00€5mg497.00€10mg701.00€25mg1,094.00€50mg1,508.00€100mg1,931.00€200mg2,637.00€CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34PF-562271 hydrochloride
CAS:PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.Formula:C21H20F3N7O3SHClPurity:98.52%Color and Shape:SolidMolecular weight:543.95Vevorisertib
CAS:Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor with inhibitory effects on AKT1/AKT2/AKT3.Formula:C35H38N8OPurity:99.14%Color and Shape:SolidMolecular weight:586.73Delcasertib acetate
Delcasertib acetate is a selective δ protein kinase C (δPKC) inhibitor for the study of acute myocardial infarction and pain.Formula:C122H203N45O36S2Purity:98.92%Color and Shape:SolidMolecular weight:2940.33Go6976
CAS:Go6976 is a PKC inhibitor, widely used in research to probe PKC functions in health and disease.Formula:C24H18N4OPurity:95.89%Color and Shape:Off-White To Yellow SolidMolecular weight:378.43Defactinib
CAS:Defactinib (VS-6063) is a second-generation inhibitor of FAK. Defactinib has potential antitumor activity. Cost-effective and quality-assured.Formula:C20H21F3N8O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:510.49Protein kinase inhibitor H-7
CAS:H-7: potent PKC inhibitor with 6 μM Ki, also blocks cyclic nucleotide-dependent kinases.Formula:C14H17N3O2SPurity:99.69%Color and Shape:SoildMolecular weight:291.37Roxifiban acetate
CAS:Roxifiban acetate(DMP 754 acetate) is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used inFormula:C23H33N5O8Purity:99.33% - 99.56%Color and Shape:SolidMolecular weight:507.54Cyclo(Ala-Arg-Gly-Asp-Mamb)
CAS:Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective antagonist of the RGD peptide with potential applications in pulmonary arterial hypertension research [1].Formula:C23H32N8O7Purity:98%Color and Shape:SolidMolecular weight:532.55Rebastinib
CAS:DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,Formula:C30H28FN7O3Purity:99.53% - 99.79%Color and Shape:SolidMolecular weight:553.59N-myristoyl-RKRTLRRL
CAS:N-myristoyl-RKRTLRRL is a compound that impedes the binding of protein kinase C (PKC) substrates and inhibits calcium (Ca2+)- and phosphatidylserine (PS)-Formula:C60H117N21O11Purity:98%Color and Shape:SolidMolecular weight:1308.71Abituzumab
CAS:Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Purity:>95%Color and Shape:LiquidChloropyramine hydrochloride
CAS:Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.Formula:C16H20ClN3·HClPurity:99.45% - 99.8%Color and Shape:SolidMolecular weight:326.26ZMF-23
ZMF-23, a PAK1/HDAC6 dual inhibitor, suppresses PAK1 and HDAC6-mediated aerobic glycolysis and cellular migration while inducing TNF-α-regulated necroptosis andFormula:C22H23Cl2N5O3Purity:98%Color and Shape:SolidMolecular weight:476.36Rottlerin
CAS:Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formula:C30H28O8Purity:97.41% - 99.44%Color and Shape:Orange To Brown PowderMolecular weight:516.54Parbendazole
CAS:Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.Formula:C13H17N3O2Purity:99.60%Color and Shape:Physical Description Crystals Or Fine White Powder (Ntp 1992)Molecular weight:247.29GMB-475
CAS:GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.Formula:C43H46F3N7O7SPurity:100% - 98.78%Color and Shape:SolidMolecular weight:861.93Ref: TM-T8488
1mg96.00€5mg200.00€10mg350.00€25mg590.00€50mg840.00€100mg1,130.00€500mg2,308.00€1mL*10mM (DMSO)274.00€TAT-SAMβA
TAT-SAMβA, an RNAENFDRF (SAMβA) peptide conjugated to the TAT 47-57 protein-derived cell-penetrating peptide, acts as a selective antagonist of the Mfn1-βIIPKCFormula:C118H195N51O31Purity:98%Color and Shape:SolidMolecular weight:2824.13Hexapeptide-10 Acetate
Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.Formula:C30H57N7O10Purity:98.84%Color and Shape:SolidMolecular weight:675.81Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formula:C22H15NO4S2Purity:98% - 98.49%Color and Shape:SolidMolecular weight:421.49PI3K-IN-48
PI3K-IN-48, a PI3K inhibitor, exhibits an IC50 of 1.55 ± 0.18 μM in A549 cells, demonstrating its potency in this context.Formula:C25H21FN2O4Purity:98%Color and Shape:SolidMolecular weight:432.44BAY1125976
CAS:BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)Formula:C23H21N5OPurity:98.87% - ≥98%Color and Shape:SolidMolecular weight:383.45Ref: TM-T7315
1mg39.00€2mg51.00€5mg88.00€10mg137.00€25mg249.00€50mg439.00€100mg647.00€500mg1,359.00€1mL*10mM (DMSO)87.00€Paeoniflorin
CAS:Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.Formula:C23H28O11Purity:96.9% - 97.16%Color and Shape:White Fine PowderMolecular weight:480.46CpCDPK1/TgCDPK1-IN-1
CAS:CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.Formula:C18H17N5Purity:98.71%Color and Shape:SolidMolecular weight:303.36Cevipabulin
CAS:Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cellFormula:C18H18ClF5N6OPurity:99.53%Color and Shape:SolidMolecular weight:464.82S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Formula:C22H21NO2SPurity:97.02%Color and Shape:Almost White To Light Yellow Granular PowderMolecular weight:363.47Litronesib
CAS:Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.Formula:C23H37N5O4S2Purity:98%Color and Shape:SolidMolecular weight:511.7Plinabulin
CAS:Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM).Formula:C19H20N4O2Purity:100% - 98.69%Color and Shape:SolidMolecular weight:336.39Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFormula:C28H26N4O3Purity:99.24% - 99.98%Color and Shape:Off-White PowderMolecular weight:466.53Ref: TM-T6680
1mg62.00€2mg87.00€5mg97.00€10mg145.00€25mg246.00€50mg401.00€100mg597.00€500mg1,283.00€1mL*10mM (DMSO)109.00€Carbenoxolone disodium
CAS:Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.Formula:C34H48Na2O7Purity:98.01%Color and Shape:SolidMolecular weight:614.72Tubulin inhibitor 1
CAS:Tubulin inhibitor 1 blocks tubulin polymerization, with strong anti-tumor effects, induces apoptosis and G2/M mitotic arrest.Formula:C21H24N2O4Purity:98%Color and Shape:SolidMolecular weight:368.43Eribulin
CAS:Eribulin binds microtubules, halts cancer cell growth, treating metastatic breast cancer.Formula:C40H59NO11Purity:99.96%Color and Shape:SolidMolecular weight:729.90Hypocrellin A
CAS:Hypocrellin A is a natural PKC inhibitor with light-induced antitumor, antifungal and antiviral activities.Cost-effective and quality-assured.Formula:C30H26O10Purity:98% - 99.81%Color and Shape:SolidMolecular weight:546.52Conteltinib
CAS:Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.Formula:C32H45N9O3SPurity:98.12% - 99.54%Color and Shape:SolidMolecular weight:635.82Ref: TM-T14997
1mg77.00€5mg167.00€10mg240.00€25mg409.00€50mg572.00€100mg800.00€1mL*10mM (DMSO)227.00€Hsp110-STAT3 interaction-IN-2
Hsp110-STAT3 interaction-IN-2 (compound 10b) is an inhibitor of the Hsp110-STAT3 interaction. It is utilized in research related to pulmonary arterial hypertension (PAH).Formula:C24H18F3N5O3Color and Shape:SolidMolecular weight:481.43AKT-IN-25
CAS:AKT-IN-25 (Compound 14a) is an inhibitor of Akt that prevents the phosphorylation of Akt, thereby hindering the PI3K/Akt/mTOR signaling pathway. It arrests the cell cycle at the G1 phase, inhibits the migration of PANC-1 cells, and suppresses the proliferation of cancer cells PANC-1, PATU-T, and SUIT-2, with IC50 values of 3.05, 1.32, and 3.85 μM, respectively.Formula:C14H16N4OColor and Shape:SolidMolecular weight:256.3Tasidotin hydrochloride
CAS:Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.Formula:C32H59ClN6O5Purity:98%Color and Shape:SolidMolecular weight:643.30CLT-28643
CAS:CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.Formula:C19H17N3O4Purity:99.98%Color and Shape:SolidMolecular weight:351.36Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formula:C22H26ClN7O2SPurity:99.59% - 99.86%Color and Shape:Pale-Yellow SolidMolecular weight:488.01DM1-SMe
CAS:DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.Formula:C36H50ClN3O10S2Purity:97.19%Color and Shape:SolidMolecular weight:784.38JB062
CAS:JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiacFormula:C19H17NO4Purity:99.49%Color and Shape:SolidMolecular weight:323.34Ref: TM-T67952
1mg185.00€5mg465.00€10mg680.00€25mg1,035.00€50mg1,406.00€100mg1,882.00€500mg3,771.00€1mL*10mM (DMSO)457.00€Gap19
CAS:Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.Formula:C55H96N14O13Purity:97.67%Color and Shape:SolidMolecular weight:1161.44Verubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormula:C17H18ClN3OPurity:98.29% - 99.77%Color and Shape:SolidMolecular weight:315.8Ref: TM-T13298
5mg50.00€10mg78.00€25mg145.00€50mg210.00€100mg300.00€200mg434.00€1mL*10mM (DMSO)56.00€SAMβA TFA
SAMβA TFA, a selective antagonist of Mfn1-βIIPKC association conjugated to the cell permeable peptide TAT47-57, is a rationally designed inhibitor that improvesFormula:C50H73N17O16·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:1168.22 (free acid)Calyxin H
CAS:Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.Formula:C35H34O7Purity:98%Color and Shape:SolidMolecular weight:566.64K-252c
CAS:K-252c is a staurosporine analog isolated from Nocardiopsis sp.Formula:C20H13N3OPurity:98%Color and Shape:SolidMolecular weight:311.34Drp1 peptide inhibitor P110
CAS:Compound P110 (Drp1 peptide inhibitor P110) is a selective Drp1 peptide inhibitor with neuroprotective effects. It inhibits the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and alleviates dopamine neuron loss, dopaminergic terminal damage, and behavioral deficits caused by MPTP. This compound is useful for Alzheimer's disease research. Additionally, Compound P110 reduces mitochondrial and organ damage in animal models of Huntington's disease, cerebral ischemia, and myocardial infarction.Formula:C100H179N45O25Color and Shape:SolidMolecular weight:2411.78Albendazole sulfoxide
CAS:Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Formula:C12H15N3O3SPurity:98.04%Color and Shape:White To Off-White PowderMolecular weight:281.33CCT251455
CAS:CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.Formula:C26H26ClN7O2Purity:99.1% - 99.1%Color and Shape:SolidMolecular weight:503.98NSC668394
CAS:NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.Formula:C17H12Br2N2O3Purity:99.29% - 99.29%Color and Shape:SolidMolecular weight:452.1SNX0723
CAS:SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.Formula:C22H26FN3O3Purity:99.86%Color and Shape:SolidMolecular weight:399.46Ref: TM-T28824
1mg89.00€5mg188.00€10mg316.00€25mg512.00€50mg702.00€100mg940.00€500mgTo inquire1mL*10mM (DMSO)207.00€Vedolizumab
CAS:Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.Purity:SDS-PAGE:98.4%;SEC-HPLC:99.1%Color and Shape:LiquidMolecular weight:146.80 kDa7-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formula:C10H12N2O5SPurity:91.05% - 98.22%Color and Shape:White Solid PowderMolecular weight:272.282-Chlorophenoxazine
CAS:2-Chlorophenoxazine is an Akt inhibitor that demonstrates an in vitro inhibitory concentration (IC50) of 2-5 μM and has the capacity to induce apoptosis.Formula:C12H8ClNOPurity:98%Color and Shape:SolidMolecular weight:217.65PD173955
CAS:PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFormula:C21H16Cl2N4OSPurity:98.52% - 99.28%Color and Shape:SolidMolecular weight:443.35Olverembatinib
CAS:Olverembatinib (GZD 824) is an orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT, IC50: 0.34 nM) and Bcr-Abl(T315I, IC50: 0.68 nM).Formula:C29H27F3N6OPurity:100% - 99.29%Color and Shape:SolidMolecular weight:532.56Ref: TM-T3071
1mg35.00€2mg48.00€5mg70.00€10mg96.00€25mg210.00€50mg338.00€100mg535.00€1mL*10mM (DMSO)82.00€Thiocolchicine
CAS:Thiocolchicine inhibits tubulin polymerization (IC50: 2.5 µM, Ki: 0.7 µM), induces apoptosis, and serves as an ADC cytotoxin.Formula:C22H25NO5SPurity:98.19%Color and Shape:SolidMolecular weight:415.5Kanosamine hydrochloride
CAS:Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species.Formula:C6H14ClNO5Purity:98%Color and Shape:SolidMolecular weight:215.63Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Formula:C29H31N7O·CH4SO3Purity:100% - 99.97%Color and Shape:White Crystalline PowderMolecular weight:589.71KG-548
CAS:KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, inhibiting lactate production, and can be used in cancer research.Formula:C9H4F6N4Purity:99.62%Color and Shape:SolidMolecular weight:282.15Y15
CAS:Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity,Formula:C6H14Cl4N4Purity:98% - 98%Color and Shape:Dark Brown CrystalsMolecular weight:284.01Ref: TM-T7119
10mg50.00€25mg69.00€50mg82.00€100mg137.00€200mg188.00€500mg331.00€1mL*10mM (DMSO)48.00€Tubulin polymerization-IN-55
CAS:Tubulin polymerisation-IN-55 is a Tubulin Polymerization inhibitor that displays antiproliferative effects on A549, K562, HepG2, MDA-MB-231 and HFL-1.Formula:C22H24N2O4Purity:98.68%Color and Shape:SoildMolecular weight:380.44T807
CAS:T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).Formula:C16H10FN3Purity:99.72%Color and Shape:SolidMolecular weight:263.27Ref: TM-T19573
2mg47.00€5mg70.00€10mg107.00€25mg187.00€50mg323.00€100mg550.00€200mg758.00€500mg1,159.00€BCR-ABL-IN-1
CAS:BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.Formula:C23H21F4N5OPurity:98%Color and Shape:SolidMolecular weight:459.44MK-2206 free base
CAS:MK-2206 free base is an allosteric Akt inhibitor that is both potent and selective, administered orally, exhibiting IC50 values of 8, 12, and 65 nM for Akt1,Formula:C25H21N5OPurity:98%Color and Shape:SolidMolecular weight:407.47ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Formula:C28H24Cl2FN5O2Purity:98.38%Color and Shape:SolidMolecular weight:552.43PKC-θ inhibitor hcl
CAS:PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).Formula:C20H26ClF3N6O3Purity:98.93%Color and Shape:SolidMolecular weight:490.91Ref: TM-T5817
1mg93.00€2mg120.00€5mg233.00€10mg376.00€25mg628.00€50mg895.00€100mg1,216.00€500mg2,432.00€KT D606
CAS:KT D606 is a PAK kinase family inhibitor with an IC50 of 4 μM. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.Formula:C59H50N6O10Color and Shape:SolidMolecular weight:1003.06Cyclo(RGDyK)
CAS:Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Formula:C27H41N9O8Purity:98%Color and Shape:SolidMolecular weight:619.68Cyclo(-RGDfK) TFA
CAS:Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).Formula:C29H42F3N9O9Purity:98.99% - 99.54%Color and Shape:SolidMolecular weight:717.69HSP90-IN-23
HSP90-IN-23 (Comp 12-1), a heat shock protein 90 (HSP90) inhibitor, exhibits potent activity with an IC50 of 9nM.Formula:C22H24N2O6SPurity:98%Color and Shape:SolidMolecular weight:444.5FAK activator 1
CAS:ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.Formula:C23H26F3N3O3Purity:98.85%Color and Shape:SoildMolecular weight:449.47Ref: TM-T77665
1mg99.00€5mg229.00€10mg383.00€25mg627.00€50mg1,005.00€100mg1,589.00€200mg2,078.00€1mL*10mM (DMSO)296.00€DN401
CAS:DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 = 698 nM for Hsp90) with potent anticancer activity.Formula:C13H9BrClN5O2Purity:100%Color and Shape:SolidMolecular weight:382.6Ref: TM-T27193
1mg185.00€5mg409.00€10mg605.00€25mg938.00€50mg1,293.00€100mg1,738.00€500mg3,496.00€1mL*10mM (DMSO)406.00€TRAP1-IN-2
CAS:TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein that does not affect Hsp90-cytosolic clients.Formula:C46H42F6N2O5P2Purity:98%Color and Shape:SolidMolecular weight:878.77Ethoxyquin
CAS:Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.Formula:C14H19NOPurity:95.94%Color and Shape:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Molecular weight:217.31CWHM-12
CAS:CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).Formula:C26H32BrN5O6Purity:98.05% - 98.5%Color and Shape:SolidMolecular weight:590.47Ref: TM-TQ0250
1mg40.00€2mg52.00€5mg88.00€10mg126.00€25mg221.00€50mg369.00€100mg550.00€1mL*10mM (DMSO)96.00€Protein Kinase C 19-31 acetate
PKC 19-31 acetate, a serine-altered PKCa-derived PKC inhibitor, tests PKC activity.Formula:C69H122N26O18Purity:100%Color and Shape:SolidMolecular weight:1603.9NVS-PAK1-1
CAS:NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Formula:C23H25ClF3N5OPurity:99.35%Color and Shape:SolidMolecular weight:479.93Volociximab
CAS:Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.Purity:95%Color and Shape:Liquid2119738-71-3
CAS:Compound 2119738-71-3 interacts with the FAK receptor.Formula:C25H29ClFN7O2Purity:98%Color and Shape:SolidMolecular weight:513.99AD57
CAS:AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.Formula:C22H20F3N7OPurity:98.23%Color and Shape:SoildMolecular weight:455.44Ref: TM-T22552L
1mg34.00€2mg52.00€5mg116.00€10mg212.00€25mg359.00€50mg512.00€100mg695.00€200mg939.00€1mL*10mM (DMSO)134.00€Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formula:C14H17N3O2SPurity:99.79% - 99.84%Color and Shape:SolidMolecular weight:291.37PKCη pseudosubstrate inhibitor,myristoylated
CAS:Myristoylated PKCη pseudosubstrate inhibitor is a cell-permeable compound utilized to investigate the mechanism of action of PKCη [1].Formula:C101H185N41O23SPurity:98%Color and Shape:SolidMolecular weight:2373.88Dynamin IN-2
CAS:Dynamin IN-2 (compound 43) is a Wiskostatin analogue.Formula:C22H21ClN2OPurity:98.81% - 98.83%Color and Shape:SoildMolecular weight:364.87Ref: TM-T64369
1mg140.00€5mg331.00€10mg439.00€25mg667.00€50mg894.00€100mg1,198.00€200mg1,596.00€1mL*10mM (DMSO)341.00€Ifebemtinib hydrochloride
Ifebemtinib (BI-853520) hydrochloride is a potent FAK (focal adhesion kinase) inhibitor with oral bioavailability, exhibiting an IC50 of 1 nM for recombinant FAK. Ifebemtinib hydrochloride demonstrates antiproliferative activity against cancer cells.Formula:C28H29ClF4N6O4Color and Shape:SolidMolecular weight:625.01Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56Compound 1T-0219 (SC)
CAS:Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620Formula:C20H19N3O7Purity:90%Color and Shape:SolidMolecular weight:413.38PF-AKT400
CAS:PF-AKT400 (AKT protein kinase inhibitor) is a broadly selective and ATP-competitive inhibitor of Akt.Formula:C20H22F2N6OPurity:98.21%Color and Shape:SolidMolecular weight:400.43Ref: TM-T5508
1mg95.00€5mg227.00€10mg325.00€25mg550.00€50mg787.00€100mg1,093.00€1mL*10mM (DMSO)250.00€BIO-1211
CAS:BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Formula:C36H48N6O9Purity:99.33%Color and Shape:SolidMolecular weight:708.8D-ERYTHRO-SPHINGOSINE
CAS:D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activatorFormula:C18H37NO2Purity:98% - ≥98%Color and Shape:SolidMolecular weight:299.49Arimoclomol
CAS:Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Formula:C14H20ClN3O3Purity:99.81%Color and Shape:SolidMolecular weight:313.78Ref: TM-T13553
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)249.00€Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFormula:C26H44NNaO5SPurity:99.79% - 99.93%Color and Shape:SolidMolecular weight:505.69Indatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Color and Shape:LiquidMolecular weight:145.5 kDaBalamapimod
CAS:Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.Formula:C30H32ClN7OSPurity:98%Color and Shape:SolidMolecular weight:574.14AG1024
CAS:AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).Formula:C14H13BrN2OPurity:98% - 99.37%Color and Shape:SolidMolecular weight:305.17Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formula:C26H29N3O3Purity:99.43% - 99.67%Color and Shape:SolidMolecular weight:431.53Ref: TM-T6345
1mg35.00€5mg66.00€10mg81.00€25mg159.00€50mg280.00€100mg470.00€500mg1,035.00€1mL*10mM (DMSO)70.00€BMS-688521
CAS:BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.Formula:C26H19Cl2N5O4Purity:98.87%Color and Shape:SolidMolecular weight:536.37Ref: TM-T14676
1mg183.00€5mg464.00€10mg655.00€25mg1,169.00€50mg1,539.00€100mg1,882.00€1mL*10mM (DMSO)547.00€AT-533
CAS:AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.Formula:C23H30N4O3Purity:99.54%Color and Shape:SoildMolecular weight:410.51Ref: TM-T67836
1mg51.00€5mg111.00€10mg170.00€25mg313.00€50mg467.00€100mg672.00€200mg905.00€1mL*10mM (DMSO)117.00€Azelaoyl PAF
CAS:Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.Formula:C33H66NO9PColor and Shape:SolidMolecular weight:651.85BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Formula:C27H24F5N5O3Purity:95.71% - 98.78%Color and Shape:SolidMolecular weight:561.5CIB-L43
CAS:CIB-L43 is an orally active TRBP inhibitor (KD = 4.78 nM) that disrupts the TRBP-dicer interaction (IC50 = 2.34 μM). It suppresses the biosynthesis of oncogenic miR-21, elevates PTEN and Smad7 expression, and inhibits AKT and TGF-β signaling, thereby reducing the proliferation and migration of HCC cells.Formula:C15H16N2O3SColor and Shape:SolidMolecular weight:304.364BCR-ABL-IN-8
CAS:BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].Formula:C30H33N7O5Purity:98%Color and Shape:SolidMolecular weight:571.63Abciximab
CAS:Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Purity:SDS-PAGE:95.2%;SEC-HPLC:95.9%Color and Shape:LiquidMolecular weight:95.18 kDaVerbascoside
CAS:Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Formula:C29H36O15Purity:97.46% - 99.55%Color and Shape:SolidMolecular weight:624.59ML-B01
ML-B01 is an orally active inhibitor targeting Akt and PKA, with IC50 values of 2 nM and 136 nM, respectively. It demonstrates good blood-brain barrier (BBB) permeability in mice.Formula:C24H31Cl2N5OColor and Shape:SolidMolecular weight:476.44MSN-125
CAS:MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.Formula:C36H38BrN3O6Purity:98%Color and Shape:SolidMolecular weight:688.61Dihydrocytochalasin B
CAS:Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.Formula:C29H39NO5Purity:98%Color and Shape:SolidMolecular weight:481.62Ipatasertib
CAS:Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Formula:C24H32ClN5O2Purity:98.28% - 99.21%Color and Shape:SolidMolecular weight:458αVβ8-IN-1
CAS:αVβ8-IN-1 is an inhibitor of the αVβ8 integrin. It exhibits growth-suppressive activity against tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 is suitable for research related to idiopathic pulmonary fibrosis (IPF), nonspecific interstitial pneumonia (NSIP), and various cancers.Formula:C25H32ClN5O4Color and Shape:SolidMolecular weight:502.01FRAX486 HCL(1232030-35-1 free base)
FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Formula:C25H24Cl3FN6OPurity:98.85% - 99.82%Color and Shape:SolidMolecular weight:549.86Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Color and Shape:Odour LiquidPF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Formula:C26H34F3N5O7SPurity:99% - 99.46%Color and Shape:SolidMolecular weight:617.63Ref: TM-T4342
1mg78.00€2mg100.00€5mg159.00€10mg288.00€25mg419.00€50mg615.00€100mg878.00€500mg1,776.00€1mL*10mM (DMSO)233.00€TCS 21311
CAS:TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ & GSK3β; >100x selective over JAK1, JAK2, TYK2.Formula:C27H25F3N4O4Purity:≥98%Color and Shape:SolidMolecular weight:526.51Bimosiamose
CAS:Bimosiamose has anti-inflammatory effects[1].Formula:C46H54O16Purity:98%Color and Shape:SolidMolecular weight:862.91αvβ1 integrin-IN-1
CAS:αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Formula:C26H34N6O6SPurity:100% - 99.74%Color and Shape:SolidMolecular weight:558.65Ref: TM-T13473
1mg115.00€5mg274.00€10mg432.00€25mg697.00€50mg938.00€100mg1,293.00€200mg1,738.00€1mL*10mM (DMSO)349.00€Cilengitide TFA
CAS:Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formula:C29H41F3N8O9Color and Shape:SolidMolecular weight:702.68DB07107
CAS:DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).Formula:C23H22N4OPurity:98%Color and Shape:SolidMolecular weight:370.45Estramustine
CAS:Estramustine (LEO-275), a nitrogen mustard-estradiol compound, treats prostate cancer and protects against radiation.Formula:C23H31Cl2NO3Purity:98.09%Color and Shape:SolidMolecular weight:440.4Ref: TM-T20681
5mg47.00€10mg70.00€25mg126.00€50mg202.00€100mg329.00€200mg487.00€1mL*10mM (DMSO)50.00€Lifitegrast sodium
CAS:Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Formula:C29H23Cl2N2NaO7SPurity:99.33%Color and Shape:SolidMolecular weight:637.46Ro 31-8220 Mesylate
CAS:Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.Formula:C25H23N5O2S·CH4O3SPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:553.65Ref: TM-T6643
1mg52.00€2mg67.00€5mg97.00€10mg159.00€25mg244.00€50mg338.00€100mg500.00€1mL*10mM (DMSO)140.00€Blinatumomab
CAS:Blinatumomab (AMG-10,MT-103) is a CD19/CD3 bispecific B-cell and T-cell binding antibody that in acute lymphoblastic leukemia and non-Hodgkin's lymphoma.Color and Shape:LiquidPironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formula:C19H32O4Purity:98%Color and Shape:SolidMolecular weight:324.45ALK inhibitor 2
CAS:ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.Formula:C23H28ClN7O3SPurity:99% - 99.77%Color and Shape:SolidMolecular weight:518.03HS-27
CAS:HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.Formula:C52H60N6O12SPurity:97.09%Color and Shape:SolidMolecular weight:993.13Ref: TM-T18018
1mg90.00€5mg215.00€10mg344.00€25mg612.00€50mg848.00€100mg1,159.00€1mL*10mM (DMSO)378.00€Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purity:95% - 99.19%Color and Shape:Yellow To Orange SolidMolecular weight:383.83Bosutinib hydrate
CAS:Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.Formula:C26H31Cl2N5O4Purity:99.87%Color and Shape:SolidMolecular weight:548.46Synstatin (92-119)
CAS:Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFormula:C133H207N35O46Purity:98%Color and Shape:SolidMolecular weight:3032.27GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Formula:C29H37N7O5SPurity:100% - 99.70%Color and Shape:SolidMolecular weight:595.71PAK4-IN-3
PAK4-IN-3 (compound 27e) is a PAK4 inhibitor exhibiting an IC50 of 10 nM and demonstrates antiproliferative effects on A549 cells with an IC50 of 0.61μM.Purity:98%Color and Shape:Odour SolidAurothiomalate sodium
CAS:Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Formula:C4H3AuNa2O4SPurity:99.66%Color and Shape:SoildMolecular weight:390.07Capivasertib
CAS:Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.Formula:C21H25ClN6O2Purity:97.59% - 99.6%Color and Shape:SolidMolecular weight:428.92Ref: TM-T1920
1mg40.00€2mg52.00€5mg70.00€10mg99.00€25mg168.00€50mg246.00€100mg378.00€200mg610.00€1mL*10mM (DMSO)89.00€Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Formula:C24H31N3O3Purity:98.05% - 99.82%Color and Shape:SolidMolecular weight:409.52Norathyriol
CAS:Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.Formula:C13H8O6Purity:98.90% - 98.93%Color and Shape:SolidMolecular weight:260.2Ref: TM-TN1990
1mg149.00€5mg354.00€10mg528.00€25mg852.00€50mg1,159.00€100mg1,568.00€1mL*10mM (DMSO)522.00€α7β1 integrin modulator-1
CAS:α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].Formula:C23H29N3O6SPurity:98%Color and Shape:SolidMolecular weight:475.56AS2521780
CAS:AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).Formula:C30H41N7OSPurity:98%Color and Shape:SolidMolecular weight:547.76Dasatinib hydrochloride
CAS:Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).Formula:C22H27Cl2N7O2SPurity:99.88% - 99.98%Color and Shape:SolidMolecular weight:524.47Pep2m, myristoylated acetate
Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.Formula:C65H122N18O16SPurity:99.62%Color and Shape:SolidMolecular weight:1443.96PKC 20-28,myristoylated
Myristoylated protein kinase C inhibitor 20-28 (PKC 20-28,myristoylated) is a cell-permeable inhibitor of protein kinase C, utilized in cancer research [1].Formula:C60H106N18O11Purity:98%Color and Shape:SolidMolecular weight:1255.6CMPD101
CAS:CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formula:C24H21F3N6OPurity:98.34% - 99.01%Color and Shape:SolidMolecular weight:466.46TPPB
CAS:TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).Formula:C27H30F3N3O3Purity:98.00%Color and Shape:SolidMolecular weight:501.54DCP-LA
CAS:DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.Formula:C20H36O2Purity:98%Color and Shape:SolidMolecular weight:308.5Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Color and Shape:LiquidEgaptivon pegol
CAS:Egaptivon pegol (ARC1779) is an aptamer that inhibits the interaction of von Willebrand Factor (VWF) with platelet GPIb receptors, exhibiting anti-thromboticPurity:98%Color and Shape:LiquidKinesore
CAS:Kinesore is a cell-permeable modulator that binds to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 and SKIP.Formula:C20H16Br2N4O4Purity:97.24%Color and Shape:SolidMolecular weight:536.17Ref: TM-T15663
2mg43.00€5mg66.00€10mg94.00€25mg159.00€50mg230.00€100mg346.00€200mg520.00€1mL*10mM (DMSO)74.00€Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.Formula:C19H34N8O11Purity:99.81%Color and Shape:SolidMolecular weight:550.52(R)-Fangchinoline
CAS:(R)-Fangchinoline ((+)-Thalrugosine) is extracted from Stephania tetrandra S. Moore.Formula:C37H40N2O6Purity:98% - 99.72%Color and Shape:SolidMolecular weight:608.72Protein Kinase C (19-31)
CAS:Protein Kinase C (19-31), a PKC inhibitor derived from PKCa, has a serine at position 25 and tests PKC activity.Formula:C67H118N26O16Purity:98%Color and Shape:Lyophilized PowderMolecular weight:1543.82Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formula:C26H31N7O4SPurity:99.25%Color and Shape:SolidMolecular weight:537.63Ref: TM-T16130
2mg42.00€5mg64.00€10mg92.00€25mg170.00€50mg311.00€100mg449.00€200mg630.00€1mL*10mM (DMSO)74.00€Antitumor agent-86
CAS:Antitumor agent-86 targets MCF-7 cells with 2.62 µM IC50, induces apoptosis, and disrupts RAS/PI3K/Akt/JNK pathways.Formula:C29H31N5O2SPurity:98%Color and Shape:SolidMolecular weight:513.65[Ala107]-MBP (104-118) acetate
[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP).Formula:C59H108N20O21Purity:99.23%Color and Shape:SolidMolecular weight:1553.72Myosin V-IN-1
CAS:Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.Formula:C29H26N6O3SPurity:97.31% - 97.31%Color and Shape:SolidMolecular weight:538.62Ref: TM-T72060
1mg314.00€5mg663.00€10mg944.00€25mg1,396.00€50mg1,890.00€100mg2,547.00€1mL*10mM (DMSO)677.00€DPH
CAS:DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.Formula:C18H13FN4O2Purity:99.72%Color and Shape:SolidMolecular weight:336.32BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Formula:C24H30N8OPurity:99.37%Color and Shape:SolidMolecular weight:446.55AKT Kinase Inhibitor
CAS:AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.Cost-effective and quality-assured.Formula:C16H19N7O3Purity:98.53% - 99.86%Color and Shape:SolidMolecular weight:357.37Ref: TM-T10276
1mg136.00€5mg329.00€10mg567.00€25mg887.00€50mg1,188.00€100mg1,605.00€1mL*10mM (DMSO)360.00€CCB02
CAS:CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.Formula:C14H9N3OPurity:99.51%Color and Shape:SolidMolecular weight:235.24Ref: TM-T10704
1mg115.00€5mg274.00€10mg432.00€25mg845.00€50mg1,293.00€100mg1,768.00€1mL*10mM (DMSO)303.00€p5 Ligand for Dnak and DnaJ acetate
p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).Formula:C46H85N15O13SPurity:96.33%Color and Shape:SolidMolecular weight:1088.32DOTA-cyclo(RGDfK)
CAS:DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.Formula:C43H67N13O14Color and Shape:SoildMolecular weight:990.07Psychosine
CAS:Psychosine (Galactosylsphingosine) is a PKC inhibitor, and is highly cytotoxic, inducing cell death in a variety of cells.Formula:C24H47NO7Purity:98%Color and Shape:White PowderMolecular weight:461.63BI-1950
CAS:BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.Formula:C32H26Cl2FN7O3Purity:98%Color and Shape:SolidMolecular weight:646.5KU-177
CAS:KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Formula:C27H23NO8Purity:97.34% - 98.54%Color and Shape:SolidMolecular weight:489.47KIF18A-IN-16
CAS:KIF18A-IN-16 (Compound 15) is a polycyclic KIF18A inhibitor. It is applicable in research related to tumors, including colon cancer, breast cancer, and lung cancer.Formula:C30H37N5O4SColor and Shape:SolidMolecular weight:563.71N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS:N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nMFormula:C24H18ClN3OPurity:98.65%Color and Shape:SoildMolecular weight:399.87Ref: TM-T60041
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€200mg1,454.00€1mL*10mM (DMSO)279.00€GNF-7
CAS:GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.Formula:C28H24F3N7O2Purity:97.05% - 99.47%Color and Shape:SolidMolecular weight:547.53(-)-Indolactam V
CAS:(-)-Indolactam V: PKC activator, antitumor, Ki 3.36 nM/1.03 μM for η/γ-CRD2, Kd 5.5-213 nM for C1 domains.Formula:C17H23N3O2Purity:98%Color and Shape:SolidMolecular weight:301.38ZINC194100678
CAS:ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.Formula:C10H13N5OPurity:98.3%Color and Shape:SolidMolecular weight:219.24Tau-aggregation and neuroinflammation-IN-1
CAS:Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.Formula:C25H20N2O7Purity:100%Color and Shape:SolidMolecular weight:460.44VER49009
CAS:VER49009 (CCT0129397) is an effective HSP90 inhibitor(IC50 =25 nM, Kd=78 nM).Formula:C19H18ClN3O4Purity:100% - 99.17%Color and Shape:SolidMolecular weight:387.82Ref: TM-T2268
1mg60.00€2mg85.00€5mg111.00€10mg167.00€25mg283.00€50mg472.00€100mg643.00€1mL*10mM (DMSO)96.00€HSDVHK-NH2 acetate
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).Formula:C32H52N12O11Purity:99.50%Color and Shape:SolidMolecular weight:780.39Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formula:C21H29N5O6Purity:99.21%Color and Shape:SolidMolecular weight:447.48FAK inhibitor 7
CAS:FAK inhibitor7, a potent FAK inhibitor, demonstrates an IC50 of 3.58 nM. This compound effectively inhibits downstream signaling cascades of FAK (such as Src and AKT), which leads to cell cycle arrest at the G0/G1 phase and induces cytotoxic autophagy in ovarian cancer cells. Additionally, FAK inhibitor7 has been shown to suppress tumor metastasis and growth in ovarian cancer mouse models.Formula:C32H37N7O3Color and Shape:SolidMolecular weight:567.68ALK-IN-29
ALK-IN-29 (compound 4c) exhibits inhibitory effects on tyrosine protein kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, displaying a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is applicable in cancer research.Formula:C29H32FN3OColor and Shape:SolidMolecular weight:457.58MPT0B014
CAS:MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.Formula:C19H17NO4Purity:99.56%Color and Shape:SolidMolecular weight:323.34PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Formula:C22H27N5O4Purity:96.27% - ≥95%Color and Shape:SolidMolecular weight:425.48KU-32
CAS:KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.Formula:C20H25NO8Purity:98%Color and Shape:SolidMolecular weight:407.41iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formula:C35H57N13O14S2Purity:98.77%Color and Shape:SolidMolecular weight:948.04S-methyl DM1
CAS:S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.Formula:C36H50ClN3O10SPurity:98%Color and Shape:SolidMolecular weight:752.31HSP90-IN-22
CAS:HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM inFormula:C25H30N4O3Purity:98%Color and Shape:SolidMolecular weight:434.53
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