Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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Cenisertib
CAS:Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as wellFormula:C24H30FN7OColor and Shape:SolidMolecular weight:451.54XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurity:99.07%Color and Shape:SolidMolecular weight:437.54Ref: TM-T17267
1mg56.00€2mg78.00€5mg99.00€10mg149.00€25mg258.00€50mg393.00€100mg582.00€1mL*10mM (DMSO)110.00€Bisindolylmaleimide VIII acetate
CAS:Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Formula:C26H26N4O4Purity:99.27%Color and Shape:SolidMolecular weight:458.51PKC-ε translocation inhibitor peptide
PKC-ε Translocation Inhibitor Peptide is a selective modulator that controls the FcγR-mediated internalization rate of opsonized beads without affecting FcαRPurity:98%Color and Shape:Odour SolidArg-Gly-Asp TFA (99896-85-2(free base))
Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.Formula:C14H23F3N6O8Purity:99.2% - ≥98%Color and Shape:SolidMolecular weight:460.36STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Purity:95% - 95%Color and Shape:Odour LiquidEMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Formula:C25H31F3N4O2Purity:98%Color and Shape:SolidMolecular weight:476.53Nilotinib monohydrochloride monohydrate
CAS:Nilotinib monohydrochloride monohydrate (Nilotinib (monohydrochloride monohydrate)) is significantly potent BCR-ABL against, is a second generation tyrosineFormula:C28H22F3N7O·HCl·H2OPurity:99.93%Color and Shape:SolidMolecular weight:583.99Anti-Mouse IL-1a Antibody (ALF-161)
Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.Purity:98%Color and Shape:Odour SolidDanicamtiv
CAS:Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Formula:C16H20F3N5O4SPurity:99.38%Color and Shape:SolidMolecular weight:435.42Ref: TM-T15050
1mg136.00€5mg274.00€10mg454.00€25mg750.00€50mg1,026.00€100mg1,406.00€1mL*10mM (DMSO)303.00€LY 379196
LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.Formula:C30H34N4O5SColor and Shape:SolidMolecular weight:562.68XL888
CAS:XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.Formula:C29H37N5O3Purity:98.1%Color and Shape:SolidMolecular weight:503.64Loureirin A
CAS:Loureirin A inhibits platelet aggregation and PI3K/Akt signaling, promotes hair follicle repair, and has anti-fibrotic and anti-angiogenic properties.Formula:C17H18O4Purity:99.83% - 99.84%Color and Shape:SolidMolecular weight:286.32Ref: TM-T5S0896
1mg74.00€5mg133.00€10mg188.00€25mg329.00€50mg490.00€100mg697.00€200mg938.00€1mL*10mM (DMSO)207.00€Mitoxantrone
CAS:Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Formula:C22H28N4O6Purity:97.97% - 98.74%Color and Shape:Blue PowderMolecular weight:444.48CID-663143
CAS:CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.Formula:C19H18N4O2SPurity:99.56% - 99.68%Color and Shape:SolidMolecular weight:366.44Ref: TM-T23889
1mg77.00€5mg158.00€10mg225.00€25mg338.00€50mg475.00€100mg638.00€200mg845.00€1mL*10mM (DMSO)164.00€Soblidotin
CAS:Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.Formula:C39H67N5O6Purity:97.48%Color and Shape:SolidMolecular weight:701.98DCPLA-ME
CAS:DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerativeFormula:C21H38O2Purity:98.16%Color and Shape:SolidMolecular weight:322.53Ref: TM-T10980
1mg65.00€5mg133.00€10mg180.00€25mg369.00€50mg605.00€100mg815.00€200mg1,111.00€1mL*10mM (DMSO)145.00€MT189
CAS:MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.Formula:C21H18FN3O2Purity:98.67%Color and Shape:SoildMolecular weight:363.38G-5555 hydrochloride (1648863-90-4 free base)
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.Formula:C25H26Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:529.42TAS0612
CAS:TAS0612, a novel oral inhibitor of RSK, AKT, and S6K, exhibits broad-spectrum antitumor activity by impeding cell growth [1].Formula:C27H34F3N9O2Purity:98%Color and Shape:SolidMolecular weight:573.61Recilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Formula:C16H13ClO4SPurity:98.85% - 98.96%Color and Shape:SolidMolecular weight:336.79Ref: TM-T13862
1mg46.00€2mg59.00€5mg87.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)105.00€LP-261
CAS:LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.Formula:C22H19N3O4SPurity:99.76%Color and Shape:SolidMolecular weight:421.47Ref: TM-T9595
1mg38.00€2mg49.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€1mL*10mM (DMSO)87.00€Sabizabulin
CAS:Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.Formula:C21H19N3O4Purity:98.04% - 99.76%Color and Shape:SolidMolecular weight:377.39Ref: TM-T17228
1mg145.00€2mg207.00€5mg354.00€10mg547.00€25mg880.00€50mg1,198.00€100mg1,596.00€500mg3,220.00€KOdiA-PC
CAS:KOdiA-PC is a truncated oxidized phospholipid and a CD36-targeting ligand found on oxLDL. It inhibits activation of TLR4 signaling components.Formula:C32H58NO11PColor and Shape:SolidMolecular weight:663.78PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Purity:95.01%Color and Shape:SoildMps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Formula:C26H36N6O3Purity:96.24% - 99.75%Color and Shape:SolidMolecular weight:480.6Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:SolidMolecular weight:438.48Ref: TM-T6278
1mg49.00€5mg96.00€10mg166.00€25mg313.00€50mg553.00€100mg790.00€500mg1,578.00€1mL*10mM (DMSO)115.00€K-80003
CAS:K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.Formula:C22H21FO2Purity:99.76%Color and Shape:SolidMolecular weight:336.4Ref: TM-T11734
1mg49.00€5mg104.00€10mg166.00€25mg283.00€50mg430.00€100mg633.00€500mg1,349.00€1mL*10mM (DMSO)115.00€Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Formula:C27H36N6O3Purity:99.53%Color and Shape:SolidMolecular weight:492.61Rotigaptide TFA(355151-12-1 free base)
Rotigaptide TFA is a Cx43 modulator & AAP that maintains gap junctions & cell communication under stress.Formula:C30H40F3N7O11Purity:99.21%Color and Shape:SolidMolecular weight:731.67PROTAC Hsp90α degrader 1
Compound X10g (PROTAC Hsp90α degrader 1) is a selective agent targeting Hsp90α for degradation and is utilized in breast cancer research.Formula:C43H50N6O7Purity:98%Color and Shape:SolidMolecular weight:762.89PF-562271 besylate
CAS:PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formula:C21H20F3N7O3S·C6H6O3SPurity:97.65% - 99.01%Color and Shape:SolidMolecular weight:665.66Ref: TM-T6177
1mg38.00€5mg79.00€10mg88.00€25mg145.00€50mg210.00€100mg313.00€200mg452.00€1mL*10mM (DMSO)95.00€Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Purity:SDS-PAGE:95% SEC-HPLC:98.77%Color and Shape:LiquidMolecular weight:146.14 kDaAntiangiogenic agent 4
Compound 3b, an antiangiogenic agent, inhibits Akt phosphorylation in both HFF and HUVEC cells and is utilized in cancer research [1].Formula:C21H24N4O3Purity:98%Color and Shape:SolidMolecular weight:380.44NAP1051
CAS:NAP1051, a biomimetic analog of Lipoxin A4, serves an anti-tumor role by targeting the inflammatory tumor microenvironment. It inhibits the chemotaxis of neutrophils to fMLP and stimulates macrophage efferocytosis by activating AKT. NAP1051 is utilized in research on colorectal cancer.Formula:C23H34O5Color and Shape:SolidMolecular weight:390.51YM-53601
CAS:YM-53601 is an SQS inhibitor that inhibits adipogenic biosynthesis and lipid secretion in rodents.YM-53601 is a cholesterol-lowering agent that inhibits FDFT1.Formula:C21H22ClFN2OPurity:99.65%Color and Shape:SolidMolecular weight:372.86FAK-IN-10
CAS:FAK-IN-10 is an inhibitor of FAK (IC50:76.3 μM).FAK-IN-10 z MCF-7 and A431 cell lines showed antitumor activity with IC50 of 4.23 and 0.78 μM, respectively.Formula:C15H10BrN3O2SPurity:99.78%Color and Shape:SoildMolecular weight:376.23FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro
CAS:FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro, also known as FITC-linked GRGDSP, is a fluorescent peptide with integrin inhibitory properties.Formula:C49H59N11O16SPurity:98%Color and Shape:SolidMolecular weight:1090.12Vodobatinib
CAS:Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.Formula:C27H20ClN3O2Purity:99.06% - 99.55%Color and Shape:SolidMolecular weight:453.92Ref: TM-T8882
1mg37.00€5mg79.00€10mg116.00€25mg212.00€50mg340.00€100mg528.00€500mg1,275.00€1mL*10mM (DMSO)87.00€Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFormula:C184H284N52O57S8·3C2H4O2Purity:99.51%Color and Shape:SolidMolecular weight:4573.21KW-2478
CAS:KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.Formula:C30H42N2O9Purity:98.68% - 99.52%Color and Shape:SolidMolecular weight:574.66Ref: TM-T6558
1mg56.00€2mg81.00€5mg119.00€10mg187.00€25mg316.00€50mg472.00€100mg662.00€1mL*10mM (DMSO)205.00€Mavacamten
CAS:Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)Formula:C15H19N3O2Purity:99.53% - 99.98%Color and Shape:SolidMolecular weight:273.33[Ala113]-MBP (104-118) acetate
[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.Formula:C69H108N20O21Purity:97.72%Color and Shape:SolidMolecular weight:1553.74Gypsogenin
CAS:Gypsogenin (639-14-5) is a naturally occurring biochemical that shows anti-ABL1 kinase and anti-chronic Myelogenous Leukemia activities.Formula:C30H46O4Purity:99.73%Color and Shape:SolidMolecular weight:470.68Ref: TM-T25476
1mg134.00€5mg315.00€10mg469.00€25mg748.00€50mg1,064.00€100mg1,415.00€1mL*10mM (DMSO)349.00€Tubulin inhibitor 7
CAS:Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (Formula:C21H14N2O4Purity:98%Color and Shape:SolidMolecular weight:358.35ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Formula:C15H11BrN2O2SPurity:99.34%Color and Shape:SolidMolecular weight:363.23Ref: TM-T13147
1mg185.00€5mg393.00€10mg587.00€25mg935.00€50mg1,264.00€100mg1,700.00€500mg3,410.00€1mL*10mM (DMSO)432.00€Benproperine phosphate
CAS:Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.Formula:C21H30NO5PPurity:99.84%Color and Shape:PowderMolecular weight:407.44Bimosiamose disodium
CAS:Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.Formula:C46H52Na2O16Purity:98%Color and Shape:SolidMolecular weight:906.88IPA-3
CAS:IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).Formula:C20H14O2S2Purity:96.7%Color and Shape:SolidMolecular weight:350.45Peptide5 TFA
Peptide5 TFA, a connexin 43 mimetic peptide, mitigates swelling, astrogliosis, and neuronal cell death in animal models of spinal cord injury.Formula:C62H99F3N16O22SPurity:98%Color and Shape:SolidMolecular weight:1509.6α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Formula:C16H26N4O11Purity:98.46%Color and Shape:SolidMolecular weight:450.4Larixol
CAS:Larixol acts as both an fMLP inhibitor and a modulator of various signaling pathways by inhibiting Src kinase, ERK1/2, p38, and AKT phosphorylation critical forFormula:C20H34O2Purity:98%Color and Shape:SolidMolecular weight:306.48BGG463
CAS:BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 μM, 0.09 μM and 0.590 μM, respectively.Formula:C30H29F3N6O3Purity:100% - 95.05%Color and Shape:SolidMolecular weight:578.58Ref: TM-T4618
1mg62.00€2mg87.00€5mg119.00€10mg188.00€25mg350.00€50mg505.00€100mg730.00€1mL*10mM (DMSO)154.00€Protein Kinase C (19-31) (TFA)(121545-65-1,free)
Protein Kinase C (19-31) TFA is a serine-modified PKCa-derived inhibitor for testing PKC activity.Formula:C69H119F3N26O18Purity:98%Color and Shape:SolidMolecular weight:1657.842',4'-DIHYDROXYCHALCONE
CAS:2',4'-DIHYDROXYCHALCONE (2',4'-DHC) as a compound with Hsp90 inhibitory and antifungal effectsFormula:C15H12O3Purity:98.95%Color and Shape:SolidMolecular weight:240.25Ref: TM-T8829
2mg42.00€5mg62.00€10mg87.00€25mg154.00€50mg235.00€100mg354.00€200mg520.00€1mL*10mM (DMSO)65.00€Triclabendazole
CAS:Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.Formula:C14H9Cl3N2OSPurity:99.11%Color and Shape:White To Brown Crystalline PowderMolecular weight:359.66Tubulin inhibitor 24
CAS:Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Formula:C22H21N3O3Purity:99.89%Color and Shape:SolidMolecular weight:375.42Rocaglamide
CAS:Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.Formula:C29H31NO7Purity:95.32% - 98.46%Color and Shape:SolidMolecular weight:505.56mP6
CAS:mP6 (Myr-FEEERA-OH), a myristoylated peptide, selectively inhibits Gα 13's interaction with integrin β 3 while preserving talin-dependent integrin function.Formula:C47H75N9O14Purity:98%Color and Shape:SolidMolecular weight:990.15HG-7-86-01
CAS:HG-7-86-01 is a selective type II tyrosine kinase inhibitor with antiproliferative activity against mutant T315I- Bcr-Abl for chronic myeloid leukemia (CML).Formula:C28H21F3N6O2SPurity:99.07%Color and Shape:SolidMolecular weight:562.57Bisindolylmaleimide V
CAS:Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.Formula:C21H15N3O2Purity:90%Color and Shape:Red SolidMolecular weight:341.36Verubulin
CAS:Verubulin (MPC 6827) is a microtubule blocking agent with cytotoxic and potentially anticancer activity that disrupts newly formed blood vessels in xenografts.Formula:C17H17N3OPurity:99.98%Color and Shape:SolidMolecular weight:279.34UMK57
CAS:UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,Formula:C17H17N3SPurity:99.81%Color and Shape:SolidMolecular weight:295.4Thiabendazole
CAS:Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.Formula:C10H7N3SPurity:99.14%Color and Shape:Light Yellow PowderMolecular weight:201.25PKCβII Peptide Inhibitor I
CAS:PKCβII Peptide Inhibitor I, a specific PKCβII inhibitor, exhibits cardioprotective properties in a rat cardiac ischemia/reperfusion injury model and mitigatesFormula:C61H94N12O19Purity:98%Color and Shape:SolidMolecular weight:1299.47EL-102
CAS:EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.Formula:C19H16N2O3S2Purity:99.34%Color and Shape:SolidMolecular weight:384.47Ref: TM-T15205
1mg87.00€5mg216.00€10mg349.00€25mg545.00€50mg740.00€100mg1,103.00€1mL*10mM (DMSO)183.00€AG957
CAS:Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling inFormula:C15H15NO4Purity:98.82%Color and Shape:SolidMolecular weight:273.28Ref: TM-T21785
1mg89.00€5mg212.00€10mg315.00€25mg527.00€50mg750.00€100mg1,017.00€1mL*10mM (DMSO)265.00€Adaphostin
CAS:Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.Formula:C24H27NO4Purity:97.31%Color and Shape:SolidMolecular weight:393.48Vaccarin
CAS:Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.Formula:C32H38O19Purity:99.16% - 99.97%Color and Shape:SolidMolecular weight:726.63GSK-923295
CAS:GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Formula:C32H38ClN5O4Purity:96.22% - 98.02%Color and Shape:SolidMolecular weight:592.13Ref: TM-T2039
1mg49.00€2mg70.00€5mg97.00€10mg168.00€25mg331.00€50mg510.00€100mg737.00€1mL*10mM (DMSO)136.00€Mitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Formula:C22H30Cl2N4O6Purity:100% - 99.85%Color and Shape:Blue-Black Solid From Water Ethanol SolidMolecular weight:517.4Feretoside
CAS:Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1).Formula:C17H24O11Purity:99.15%Color and Shape:SolidMolecular weight:404.37Ref: TM-TQ0280
1mg85.00€5mg180.00€10mg274.00€25mg465.00€50mg663.00€100mg919.00€500mg1,833.00€1mL*10mM (DMSO)298.00€Ombrabulin
CAS:Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.Formula:C21H26N2O6Purity:98%Color and Shape:SolidMolecular weight:402.44GW406108X
CAS:GW406108X is a Kif15 and ULK1 inhibitor; IC50: 0.82 µM (ATPase), pIC50: 6.37; blocks autophagy.Formula:C20H11Cl2NO4Purity:98%Color and Shape:SolidMolecular weight:400.2117-AEP-GA
CAS:17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.Formula:C34H50N4O8Purity:97.77% - 99.56%Color and Shape:SolidMolecular weight:642.78Tirofiban hydrochloride monohydrate
CAS:Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.Formula:C22H39ClN2O6SPurity:95.83% - 99.94%Color and Shape:White SolidMolecular weight:495.07Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFormula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24Ref: TM-TN1299
1mg178.00€5mg540.00€10mg715.00€25mg1,103.00€50mg1,491.00€100mg2,005.00€500mg4,010.00€1mL*10mM (DMSO)442.00€PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Formula:C29H36ClN5O4Purity:98%Color and Shape:SolidMolecular weight:554.08PKCβ inhibitor 1
CAS:PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,Formula:C24H21N5O2Purity:99.33%Color and Shape:SolidMolecular weight:411.46Ref: TM-T8376
1mg154.00€5mg424.00€10mg605.00€25mg920.00€50mg1,216.00€100mg1,673.00€200mg2,252.00€500µg93.00€1mL*10mM (DMSO)401.00€Ingenol
CAS:Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.Formula:C20H28O5Purity:99.78% - 99.87%Color and Shape:SolidMolecular weight:348.43Ref: TM-T5S2017
1mg52.00€5mg95.00€10mg127.00€25mg246.00€50mg467.00€100mg640.00€500mg1,359.00€1mL*10mM (DMSO)96.00€PF04929113
CAS:PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.Formula:C25H30F3N5O4Purity:99.06%Color and Shape:SolidMolecular weight:521.53Ref: TM-T6341
1mg39.00€2mg49.00€5mg84.00€10mg119.00€25mg187.00€50mg354.00€100mg527.00€1mL*10mM (DMSO)96.00€OXA-11
CAS:OXA-11 (FAK-IN-16) is a FAK inhibitor with anti-tumor activity, useful for cancer research.Formula:C37H49F3N7O5PPurity:98.70% - 99.20%Color and Shape:SolidMolecular weight:759.8cSRC/BCR-ABL1-IN-1
cSRC/BCR-ABL1-IN-1 (compound 16a) is a dual-target inhibitor of the cSRC/BCR-ABL1 kinases.Formula:C24H27ClN6O4Color and Shape:SolidMolecular weight:498.96HSP90-IN-19
CAS:HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.Formula:C29H38O7Purity:98%Color and Shape:SolidMolecular weight:498.61ATM-3507
CAS:ATM-3507 is an inhibitor of tropomyosin. In human melanoma cell lines, the IC50s are from 3.83-6.84 μM.Formula:C37H46FN5O2Purity:96.36% - 99.10%Color and Shape:SolidMolecular weight:611.79Asciminib
CAS:Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5-0.8nM).Formula:C20H18ClF2N5O3Purity:97.93% - 99.45%Color and Shape:SolidMolecular weight:449.84Ref: TM-T5177
1mg63.00€2mg92.00€5mg127.00€10mg187.00€25mg305.00€50mg427.00€100mg630.00€500mg1,320.00€1mL*10mM (DMSO)139.00€Natalizumab
CAS:Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Purity:98.00%Color and Shape:LiquidMolecular weight:N/AHSP90-IN-32
CAS:HSP90-IN-32, a carboxy-terminus inhibitor of Hsp90C, exhibits antiproliferative activity in various cell lines including SKMel173, SKMel103, SKMel19, and A375, with IC50 values of 1.01 μM, 0.782 μM, 0.607 μM, and 1.413 μM, respectively. This compound holds potential for research in anticancer agents.Formula:C33H40N2O4Color and Shape:SolidMolecular weight:528.68CW-069
CAS:CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Formula:C23H21IN2O3Purity:97.52% - 98.59%Color and Shape:SolidMolecular weight:500.33Ref: TM-T6209
1mg43.00€5mg90.00€10mg125.00€25mg216.00€50mg306.00€100mg432.00€500mg938.00€1mL*10mM (DMSO)89.00€DM4
CAS:DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.Formula:C38H54ClN3O10SPurity:98.15%Color and Shape:SolidMolecular weight:780.37NQTrp
CAS:NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.Formula:C21H16N2O4Purity:98%Color and Shape:SolidMolecular weight:360.36N-Phenylbenzylamine
CAS:A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerizationFormula:C13H13NPurity:99.93%Color and Shape:Colorless To Pale Yellow Crystalline PowderMolecular weight:183.25Curvulin
CAS:Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.Formula:C12H14O5Purity:98.97%Color and Shape:SolidMolecular weight:238.24Ref: TM-T36850
1mg145.00€5mg319.00€10mg472.00€25mg753.00€50mg1,074.00€100mg1,444.00€1mL*10mM (DMSO)284.00€Hu7691 free base
CAS:Hu7691 free base is an Akt inhibitor that inhibits Akt1, Akt2 and Akt3 and induces differentiation of neuroblastoma cells.Formula:C22H21F3N4OPurity:98.89%Color and Shape:SolidMolecular weight:414.423H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formula:C23H38N10O10Purity:100%Color and Shape:SolidMolecular weight:614.61Phenamacril
CAS:Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.Formula:C12H12N2O2Purity:99.37%Color and Shape:SolidMolecular weight:216.24Ref: TM-T24214
1mg145.00€5mg319.00€10mg472.00€25mg753.00€50mg1,074.00€100mg1,444.00€500mg2,822.00€1mL*10mM (DMSO)274.00€α-Linolenic acid
CAS:α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and lowers blood lipids. Cost-effective and quality-assured.Formula:C18H30O2Purity:98.19% - 99.81%Color and Shape:Physical Description Clear Colorless Liquid (Ntp 1992)Molecular weight:278.43Cyclo(RGDfC) TFA
Zelminemab (AMG-301) is a humanized monoclonal antibody targeting ADCYAP1R1 for use in neurological disorders.Formula:C26H35F3N8O9SPurity:98.59%Color and Shape:SolidMolecular weight:692.67ɛPKC(85-92),Myristoylated
CAS:PKC(85-92),Myristoylated is a myristic acid-conjugated, cell-permeable peptide activator of PKC that has been shown to increase nitric oxide (NO) release inFormula:C53H80N10O15Purity:98%Color and Shape:SolidMolecular weight:1097.26cRGDfK-thioacetyl ester
CAS:cRGDfK-thioacetyl ester, a bioactive polypeptide, exhibits selective affinity for integrins and can modify near-infrared (NIR) fluorescent probes for targetedFormula:C31H45N9O9SPurity:98%Color and Shape:SolidMolecular weight:719.81AZ82
CAS:AZ82 is an inhibitor of the kinesin-like protein KIFC1, which induces multipolar mitosis and apoptosis in prostate cancer cells.Formula:C28H31F3N4O3SPurity:99.31%Color and Shape:SolidMolecular weight:560.63Kazinol B
CAS:Kazinol B is an inhibitor of nitric oxide (NO) production, an isopentenylated flavan with a dimethylpyran ring.Kazinol B improves insulin sensitivity byFormula:C25H28O4Purity:98%Color and Shape:SolidMolecular weight:392.49Procyanidin A1
CAS:Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+.Formula:C30H24O12Purity:99.52%Color and Shape:SolidMolecular weight:576.5AKT Kinase Inhibitor HCl
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.Formula:C16H20ClN7O3Purity:98.87%Color and Shape:SoildMolecular weight:393.83Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formula:C26H45NO6SPurity:99.69% - 99.86%Color and Shape:SolidMolecular weight:499.7C16Y
CAS:C16Y, a short peptide, serves as an inhibitor for the integrins αvβ3 and α5β1. It targets the cell membrane and exerts its antitumor activity by inhibiting angiogenesis.Formula:C78H115N17O17Color and Shape:SolidMolecular weight:1562.85Gedunin
CAS:Gedunin, a Meliaceae seed limonoid, inhibits Hsp90 and ovarian cancer growth.Formula:C28H34O7Purity:99.38% - 99.68%Color and Shape:SolidMolecular weight:482.57Ref: TM-T21883
1mg393.00€5mg1,169.00€10mg1,596.00€25mg2,365.00€50mg3,192.00€100mg4,304.00€1mL*10mM (DMSO)1,283.00€Si306
CAS:Si306, an Src inhibitor, exhibits antitumor activity by reducing the phosphorylation of focal adhesion kinase (FAK) and the expression of epidermal growth factor receptor (EGFR), thereby inhibiting the invasion of human glioblastoma (GBM).Formula:C25H26BrClN6OSColor and Shape:SolidMolecular weight:573.94Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purity:97.10% - 99.33%Color and Shape:SolidMolecular weight:558.7Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormula:C18H17Cl2FN4OSPurity:97.51% - 99.17%Color and Shape:SolidMolecular weight:427.32Ref: TM-T1911
1mg39.00€2mg50.00€5mg79.00€10mg97.00€25mg170.00€50mg274.00€100mg477.00€500mg1,035.00€1mL*10mM (DMSO)79.00€Ζ-Stat
CAS:ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis inFormula:C10H8O10S3Purity:98.01%Color and Shape:SolidMolecular weight:384.36FRAX1036
CAS:FRAX-1036 is a effective and selective PAK1 inhibitor.Formula:C28H32ClN7OPurity:97.66% - 99.95%Color and Shape:SolidMolecular weight:518.05Ref: TM-T6839
1mg51.00€2mg69.00€5mg87.00€10mg119.00€25mg210.00€50mg354.00€100mg512.00€1mL*10mM (DMSO)97.00€JB002
CAS:JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM.Formula:C18H15NO3Purity:99.02%Color and Shape:SoildMolecular weight:293.32Ref: TM-T72023
1mg77.00€5mg169.00€10mg264.00€25mg535.00€50mg747.00€100mg1,035.00€500mg2,072.00€1mL*10mM (DMSO)180.00€Monomethyl lithospermate
CAS:Monomethyl lithospermate shows antiviral traits, aids ischemic stroke via PI5K/Akt, protects SHSY-3Y cells, and reduces oxidative stress in MCAO rats.Formula:C28H24O12Purity:98%Color and Shape:SolidMolecular weight:552.48CFI-402257
CAS:CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.Formula:C28H30N6O3Purity:96.66% - 99.51%Color and Shape:SolidMolecular weight:498.58HIV-1 protease-IN-10
HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) andFormula:C23H40O5Purity:98%Color and Shape:SolidMolecular weight:396.56PS315
CAS:PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.Formula:C23H19ClO2Purity:98%Color and Shape:SolidMolecular weight:362.85PKN1/2-IN-1
CAS:PKN1/2-IN-1 is a potent and selective PKN2 inhibitor, membrane permeability and anticancer.Protein kinase N proteins (PKN) are effectors of Rho GTPases.Formula:C14H15N3OColor and Shape:SolidMolecular weight:241.29POSH-IN-2
CAS:POSH-IN-2 (MIDI) is a mitochondrial fission inhibitor and a DRP1 inhibitor that effectively prevents mitochondrial fragmentation caused by cellular stress and genetic mitochondrial damage. It covalently interacts with DRP1-C367 to target the interaction of DRP1 with multiple receptors.Formula:C22H16N2O2Color and Shape:SolidMolecular weight:340.37BCR-ABL-IN-9
BCR-ABL-IN-9 (Compound B1) is an inhibitor of BCR-ABL that achieves sustained suppression through the formation of stable covalent bonds with the ABL kinase. It effectively inhibits the activity of ABL kinase (IC50 = 1.2 nM) and possesses anticancer activity.Formula:C22H20N4O3Color and Shape:SolidMolecular weight:388.42KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formula:C20H20N4OPurity:98.43% - 99.89%Color and Shape:SolidMolecular weight:332.4TRAP1-IN-1
TRAP1-IN-1 (compound 35) is a potent, selective TRAP1 inhibitor affecting the mitochondrial variant of Hsp90.Formula:C45H39F7N2O4P2Purity:98%Color and Shape:SolidMolecular weight:866.74Ifebemtinib FA
BI-853520 FA (Ifebemtinib FA) is an orally active inhibitor of adhesion patch kinase with anticancer and antiproliferative activity for ovarian and lung cancer.Formula:C29H30F4N6O6Purity:98.40% - 99.62%Color and Shape:SolidMolecular weight:634.58HSP90-IN-25
HSP90-IN-25 (compound 4a) is an inhibitor targeting HSP90, specifically impeding its ATPase function [1].Formula:C29H48O10Purity:98%Color and Shape:SolidMolecular weight:556.69KUNG65
CAS:KUNG65 acts as a selective Grp94 inhibitor, demonstrating a target dissociation constant (K_d) of 540 nM. It exhibits a minimum selectivity of 73-fold compared to other Hsp90 isoforms.Formula:C23H20ClFO4Color and Shape:SolidMolecular weight:414.85KIF18A-IN-15
CAS:KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, both with an IC50 range of 0.01-0.1 μM. These compounds inhibit the viability of OVCAR-3 cells, with IC50 values of 0.01-0.1 μM for EX36-A and 0-0.01 μM for EX36-B. KIF18A-IN-15 is applicable in research on tumors, including colon, breast, and lung cancers.Formula:C25H33F3N6O5SColor and Shape:SolidMolecular weight:586.63CCT128930
CAS:'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'Formula:C18H20ClN5Purity:99.07% - 99.18%Color and Shape:SolidMolecular weight:341.84Ref: TM-T6303
2mg42.00€5mg65.00€10mg94.00€25mg170.00€50mg273.00€100mg409.00€200mg652.00€1mL*10mM (DMSO)71.00€BTB-1
CAS:BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.Formula:C12H8ClNO4SPurity:99.71%Color and Shape:SolidMolecular weight:297.71Kif15-IN-2
CAS:Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.Formula:C20H20N6O4SPurity:98.17%Color and Shape:SolidMolecular weight:440.48PKCε inhibitor peptide,myristoylated
Myristoylated PKCε inhibitor peptide (Myr-PKCε-) is a cell-permeable inhibitor consisting of a peptide linked to myristic acid that specifically inhibitsFormula:C51H91N9O14Purity:98%Color and Shape:SolidMolecular weight:1054.32PU-H71 HCl
CAS:PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.Formula:C18H22ClIN6O2SPurity:98.95%Color and Shape:SoildMolecular weight:548.83αvβ1 integrin-IN-2
CAS:αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.Formula:C29H38N4O4Purity:98%Color and Shape:SolidMolecular weight:506.64Vinblastine
CAS:Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.Formula:C46H58N4O9Purity:97.42%Color and Shape:PowderMolecular weight:810.97CYP51/Hsp90-IN-1
CYP51/Hsp90-IN-1 (Compound MM4) is a dual inhibitor of CYP51 and Hsp90. This compound exhibits antifungal activity against Candida albicans and effectively suppresses key fungal virulence factors. CYP51/Hsp90-IN-1 shows potential for research in treating invasive candidiasis.Formula:C38H40F2N6O4Color and Shape:SolidMolecular weight:682.76A-205804
CAS:A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Formula:C15H12N2OS2Purity:98.07% - 98.52%Color and Shape:SolidMolecular weight:300.4Ref: TM-T2254
2mg44.00€5mg52.00€10mg81.00€25mg160.00€50mg271.00€100mg532.00€500mg1,169.00€1mL*10mM (DMSO)71.00€GPRP
CAS:GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.Formula:C18H31N7O5Color and Shape:White To Off-White PowderMolecular weight:425.48Gap 26
CAS:Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.Formula:C70H107N19O19SPurity:98.26%Color and Shape:SolidMolecular weight:1550.78Bepranemab
CAS:Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Purity:95% - 95%Color and Shape:LiquidSU6656
CAS:SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.Formula:C19H21N3O3SPurity:97% - 98.21%Color and Shape:SolidMolecular weight:371.45Ref: TM-T6997
1mg40.00€2mg51.00€5mg85.00€10mg139.00€25mg269.00€50mg449.00€100mg667.00€1mL*10mM (DMSO)88.00€TRC051384
CAS:TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke.Formula:C25H31N5O4Purity:92.66%Color and Shape:SolidMolecular weight:465.54Ref: TM-T3527
1mg37.00€5mg80.00€10mg111.00€25mg210.00€50mg298.00€100mg432.00€200mg622.00€1mL*10mM (DMSO)81.00€Meclofenamic acid
CAS:Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.Formula:C14H11Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:296.15Tubulin polymerization-IN-47
CAS:Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancerFormula:C22H21N3O3Purity:99.69%Color and Shape:SoildMolecular weight:375.42Adhibin
Adhibin is an allosteric inhibitor of RhoGAP class IX myosin (RhoGAP class IXmyosin), effectively inhibiting Myo9 ATPase in both mammals and invertebrates with an IC50 of 2.5 µM and 2.6 µM, respectively. It binds to ATPase, disrupting myosin's motor functions, blocking RhoGTPase-related signaling pathways, and affecting cellular migration, adhesion, and division. Adhibin is applicable for research in cancer metastasis.Formula:C13H9Br2NOColor and Shape:SolidMolecular weight:355.02Terflavoxate
CAS:Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine.Formula:C26H29NO4Purity:98.07%Color and Shape:SolidMolecular weight:419.51Meclofenamic acid sodium
CAS:Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Formula:C14H10Cl2NNaO2Purity:98% - 98.96%Color and Shape:SolidMolecular weight:318.14PKCα (C2-4) inhibitor peptide
PKCα (C2-4) inhibitor peptide is a specific antagonist to PKCα that impedes the α1A-adrenoreceptor agonist A-61603 [1] from inhibiting I_Kr.Formula:C47H74N14O17Purity:98%Color and Shape:SolidMolecular weight:1107.17TAT-Gap19 acetate
TAT-Gap19 acetate, a Cx43 HC inhibitor, crosses blood-brain barrier, reduces liver fibrosis in mice, and spares Cx43 GJCs.Formula:C119H212N46O26Purity:99.74%Color and Shape:SolidMolecular weight:2703.25Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Formula:C16H18N2O2SPurity:98.07%Color and Shape:SolidMolecular weight:302.39Ref: TM-T3118
1mg35.00€2mg48.00€5mg62.00€10mg87.00€25mg156.00€50mg235.00€100mg354.00€1mL*10mM (DMSO)67.00€MKLP2-IN-1
CAS:MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.Formula:C23H19BrFN3O2Color and Shape:SolidMolecular weight:468.318M2698
CAS:M2698 (MSC2363318A) is an inhibitor of p70S6K, Akt1 and Akt3 with IC50s of 1 nM. M2698 shows anti-cancer activity.Formula:C21H19ClF3N5OPurity:99.36%Color and Shape:SolidMolecular weight:449.86Ref: TM-T11928
1mg50.00€5mg105.00€10mg170.00€25mg329.00€50mg475.00€100mg655.00€200mg883.00€1mL*10mM (DMSO)123.00€JB061
JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscleFormula:C19H17NO4Purity:98.76%Color and Shape:SoildMolecular weight:323.34Ref: TM-T67951
1mg39.00€5mg84.00€10mg114.00€25mg202.00€50mg304.00€100mg452.00€500mg938.00€1mL*10mM (DMSO)92.00€KTC1101
CAS:KTC1101 is a pan-PI3K inhibitor with antiproliferative and anticancer activities, reducing phosphorylation of downstream AKT and mTOR.Formula:C21H26F2N8O3Purity:98.75%Color and Shape:SoildMolecular weight:476.48Ref: TM-T89831
1mg80.00€5mg158.00€10mg248.00€25mg495.00€50mg800.00€100mg1,283.00€1mL*10mM (DMSO)158.00€BJE6-106
CAS:BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM).Formula:C26H23NO2Color and Shape:SolidMolecular weight:381.47RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Formula:C24H19Cl3N2O4Purity:98.55%Color and Shape:SolidMolecular weight:505.78Danegaptide Hydrochloride
CAS:Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.Formula:C14H18ClN3O4Purity:99.55%Color and Shape:SolidMolecular weight:327.76Rifabutin
CAS:Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.Formula:C46H62N4O11Purity:99.27% - 99.8%Color and Shape:Red-Violet Crystalline PowderMolecular weight:847GNF-5
CAS:GNF-5, non-ATP Bcr-Abl inhibitor (IC50: 0.22±0.1 uM, wild-type), improves upon GNF-2 with better pharmacokinetics.Formula:C20H17F3N4O3Purity:98% - 99.98%Color and Shape:SolidMolecular weight:418.37CK-636
CAS:CK-636 (CK-0944636), an Arp2/3 complex inhibitor, can inhibit actin polymerization induced by the human, fission yeast and bovine Arp2/3 complex.Formula:C16H16N2OSPurity:98.10% - 98.88%Color and Shape:SolidMolecular weight:284.38Gap 27
CAS:Gap 27 is a peptide(Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile) derived from connexin 43 that is a selective gap junction blocker.Formula:C60H101N15O17Purity:100%Color and Shape:SolidMolecular weight:1304.53Pivanex
CAS:Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.Formula:C10H18O4Purity:≥98%Color and Shape:SolidMolecular weight:202.25MMAD
CAS:MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).Formula:C41H66N6O6SPurity:99.25% - 99.91%Color and Shape:SolidMolecular weight:771.06Tasiamide B
CAS:Tasiamide B is a linear peptide and Cathepsin D inhibitor discovered in the marine cyanobacterium Symploca sp. This compound serves as an excellent template for the development of aspartic protease inhibitors. Tasiamide B effectively targets skin cancer through its strong interaction with the protein HSP90.Formula:C50H74N8O12Color and Shape:SolidMolecular weight:979.17Crolibulin
CAS:Crolibulin (EPC2407) is an inhibitor of small molecule tubulin polymerization.Formula:C18H17BrN4O3Purity:98.19%Color and Shape:SolidMolecular weight:417.26Ref: TM-T15012
1mg64.00€2mg92.00€5mg137.00€10mg216.00€25mg376.00€50mg562.00€100mg753.00€1mL*10mM (DMSO)150.00€LXW7 TFA (1313004-77-1 free base)
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect.Formula:C31H49F3N12O14S2Purity:98%Color and Shape:SolidMolecular weight:934.92GSK 3008348 hydrochloride
CAS:GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.Formula:C29H37N5O2xHClPurity:99.54%Color and Shape:SolidMolecular weight:0Cyclo(RGDyK) trifluoroacetate
CAS:Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Formula:C31H43F6N9O12Purity:≥95%Color and Shape:SolidMolecular weight:847.72SS28
CAS:SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.Formula:C18H20O3Purity:98%Color and Shape:SolidMolecular weight:284.35AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formula:C26H30F3N7O2Purity:98.17% - 99.56%Color and Shape:SolidMolecular weight:529.56Ref: TM-T4053
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg187.00€50mg354.00€100mg528.00€500mg1,159.00€1mL*10mM (DMSO)92.00€Eg5-IN-1
Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 µM for Eg5.Eg5-IN-1 can be used in cancer research.Formula:C23H16ClFN4OPurity:98.21%Color and Shape:SolidMolecular weight:418.85PKCTheta-IN-2
CAS:PKCTheta-IN-2 (compound 14) is a potent and selective inhibitor of PKCθ, with an IC50 value of 0.25 nM. It demonstrates good selectivity across a broad range of kinases, including the PKC subfamily (30 kinases). Additionally, PKCTheta-IN-2 effectively inhibits the production of IL-2 in mice, where it exhibits an IC50 of 682 nM.Formula:C24H23N5O2Color and Shape:SolidMolecular weight:413.47Sabeluzole
CAS:Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.Formula:C22H26FN3O2SPurity:99.91%Color and Shape:SolidMolecular weight:415.52Zagotenemab
CAS:Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Purity:95% - > 95%Color and Shape:LiquidMolecular weight:145.3 kDaNilotinib
CAS:Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.Formula:C28H22F3N7OPurity:99.61% - 99.83%Color and Shape:Off-White SolidMolecular weight:529.52PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44Ref: TM-T8764
1mg113.00€2mg160.00€5mg230.00€10mg369.00€25mg615.00€50mg879.00€100mg1,198.00€500mg2,395.00€1mL*10mM (DMSO)240.00€gp96-II
Gp96-II is a gp96-blocking peptide that antagonizes cytokine production induced by gp96-mediated LPS. This compound is useful for research into inflammatory diseases.Formula:C200H353N59O53SColor and Shape:SolidMolecular weight:4464.37ZINC00640089
CAS:ZINC00640089: Selective LCN2 inhibitor; curbs SUM149 cell growth and AKT activity; useful for IBC research.Formula:C20H13F3N2O2Purity:98.13% - 99.27%Color and Shape:SolidMolecular weight:370.32AMP-PCP
CAS:AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.Formula:C11H18N5O12P3Purity:98%Color and Shape:SolidMolecular weight:505.21Aurothiomalate tetramer sodium
Aurothiomalate tetramer sodium, a tetrameric form of Aurothiomalate sodium, functions as an anti-arthritis gold agent. It also acts as a potent and selective inhibitor of the oncogenic PKCι signaling pathway.Color and Shape:Odour Solid2-Methoxyhydroquinone
CAS:2-Methoxyhydroquinone is a phenolic compound that reduces the production of TNF-α-induced chemokine (C-C motif) ligand 2 (CCL2) with an IC50 value of 64.3 µM. It also serves as a synthetic precursor to the Hsp90 inhibitor Geldanamycin.Formula:C7H8O3Color and Shape:SolidMolecular weight:140.14Gly3-VC-PAB-MMAE
CAS:Gly3-VC-PAB-MMAE Compound consisting of the ADC linker Gly3-VC-PAB and the microtubule inhibitor MMAE, which can be used to synthesize ADC compounds.Formula:C64H103N13O15Color and Shape:SolidMolecular weight:1294.58T-900607
CAS:T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.Formula:C14H10F5N3O4SPurity:99%Color and Shape:SolidMolecular weight:411.3HG-7-85-01
CAS:HG-7-85-01 is a novel ATP-competitive and type II tyrosine kinase inhibitor targeting both wild-type and watchman mutant BCR-ABL, PDGFRα, Kit, and Src kinases.Formula:C31H31F3N6O2SPurity:98.08%Color and Shape:SolidMolecular weight:608.68MKT-077
CAS:MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines.Formula:C21H22ClN3OS2Purity:98.2%Color and Shape:SolidMolecular weight:432BIIB021
CAS:BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).Formula:C14H15ClN6OPurity:98% - 99.82%Color and Shape:SolidMolecular weight:318.76αvβ6-IN-2
αvβ6-IN-2 (compound 20) is an effective orally active inhibitor of αvβ6 integrin (αvβ6integrin), with a pIC50 value of 7.8. It shows potential for use in research on idiopathic pulmonary fibrosis.Formula:C25H30F3N3O3Color and Shape:SolidMolecular weight:477.523-Phenyltoxoflavin
CAS:3-Phenyltoxoflavin (Phenyltoxoflavin) is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.Formula:C13H11N5O2Purity:98.84%Color and Shape:SolidMolecular weight:269.26Ref: TM-T36123
1mg57.00€5mg120.00€10mg187.00€25mg338.00€50mg512.00€100mg753.00€200mg1,035.00€1mL*10mM (DMSO)133.00€Elarofiban TFA
CAS:Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Formula:C26H34F6N4O8Purity:100%Color and Shape:SoildMolecular weight:644.56CH5138303
CAS:CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.Formula:C19H18ClN5O2SPurity:98%Color and Shape:SolidMolecular weight:415.9Imatinib impurities3
CAS:Imatinib impurities3 is a protein kinases inhibitor with IC50 values of 6.95uM, 0.245uM, 0.139uM for ABL1 wt, KIT wt, PDGFRR wt, respectively.Formula:C24H20ClN5OPurity:97.05%Color and Shape:SolidMolecular weight:429.9TRC051384 HCl
CAS:TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.Formula:C25H32ClN5O4Purity:97.55%Color and Shape:SolidMolecular weight:502.01AMP-PCP disodium
CAS:AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM.Formula:C11H16N5Na2O12P3Purity:100%Color and Shape:SolidMolecular weight:549.17VER-82576
CAS:VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.Formula:C21H23Cl2N5O2SPurity:98% - 99.16%Color and Shape:SolidMolecular weight:480.41Bafetinib
CAS:Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.Formula:C30H31F3N8OPurity:94.16% - 99.68%Color and Shape:SolidMolecular weight:576.62Ref: TM-T6311
1mg37.00€2mg52.00€5mg79.00€10mg103.00€25mg159.00€50mg188.00€100mg350.00€200mg455.00€1mL*10mM (DMSO)90.00€HSP90-IN-35
CAS:HSP90-IN-35 is an inhibitor targeting Hsp90, exhibiting anticancer activity. It demonstrates an IC50 ranging from 0.05 to 0.5 μM against Her2. Additionally, HSP90-IN-35 can be utilized in the synthesis of PROTAC.Formula:C27H33N5O5Color and Shape:SolidMolecular weight:507.58Pyrintegrin
CAS:Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.Formula:C23H25N5O3SPurity:97.81%Color and Shape:SolidMolecular weight:451.54Ref: TM-T16695
1mg82.00€2mg96.00€5mg159.00€10mg226.00€25mg435.00€50mg648.00€100mg924.00€200mg1,225.00€1mL*10mM (DMSO)168.00€KX2-361
CAS:KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFormula:C24H24FN3O2Purity:98.52% - 99.86%Color and Shape:SolidMolecular weight:405.46Ref: TM-T9411
1mg81.00€5mg170.00€10mg235.00€25mg386.00€50mg543.00€100mg730.00€200mg938.00€1mL*10mM (DMSO)182.00€Erbulozole
CAS:Erbulozole (R 55104) is a synthetic microtubule inhibitor with anti-invasive activity that induces Wernicke's encephalopathy-like neurotoxicity.Formula:C24H27N3O5SPurity:99.88%Color and Shape:SolidMolecular weight:469.55Darovasertib
CAS:Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).Formula:C22H23F3N8OPurity:98.72% - ≥95%Color and Shape:SolidMolecular weight:472.47Ref: TM-T5600
1mg52.00€5mg136.00€10mg188.00€25mg350.00€50mg522.00€100mg750.00€200mg1,026.00€1mL*10mM (DMSO)149.00€CEP-37440
CAS:CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).Formula:C30H38ClN7O3Purity:98.86% - 99.98%Color and Shape:SolidMolecular weight:580.12
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