Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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Lenaldekar
CAS:Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis.Formula:C18H14N4Purity:99.25%Color and Shape:SolidMolecular weight:286.33Ref: TM-T24398
1mg87.00€2mg124.00€5mg187.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€1mL*10mM (DMSO)178.00€H2-Gamendazole
CAS:H2-Gamendazole: inhibits spermatogenesis, cancer therapy, targets heat shock proteins & EF1α, regulates Hsp90.Formula:C18H13Cl2F3N2O2Purity:97.36%Color and Shape:SolidMolecular weight:417.21Ref: TM-T72076
1mg78.00€5mg190.00€10mg284.00€25mg505.00€50mg677.00€100mg929.00€200mg1,225.00€1mL*10mM (DMSO)215.00€TAS-301
CAS:TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.Formula:C23H19NO3Purity:99.69%Color and Shape:SolidMolecular weight:357.4Tubulin/AKT1-IN-1
Tubulin/AKT1-IN-1 (Compound D1-1) serves as an inhibitor of both tubulin polymerization and AKT pathway activation, effectively suppressing proliferation andFormula:C38H34ClNO11Purity:98%Color and Shape:SolidMolecular weight:716.13Sovilnesib
CAS:Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.Formula:C26H34F2N6O4SPurity:98.59%Color and Shape:SolidMolecular weight:564.65Ref: TM-T39994
1mg96.00€5mg235.00€10mg376.00€25mg630.00€50mg898.00€100mg1,216.00€1mL*10mM (DMSO)259.00€Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formula:C14H18ClN3O2SPurity:100% - ≥95%Color and Shape:White SolidMolecular weight:327.83AKT-IN-3
CAS:AKT-IN-3: potent oral Akt inhibitor with low hERG blockage. IC50: 1.4-1.7 nM for Akt1-3. Inhibits AGC kinases like PKA, PKC.Formula:C23H23Cl2F2N5O3Purity:98%Color and Shape:SolidMolecular weight:526.36Empesertib
CAS:Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.Formula:C29H26FN5O4SPurity:97.45% - 98.44%Color and Shape:SolidMolecular weight:559.61Ref: TM-T8487
1mg90.00€5mg183.00€10mg275.00€25mg449.00€50mg615.00€100mg848.00€200mg1,121.00€1mL*10mM (DMSO)245.00€CC-99677
CAS:CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.Formula:C22H20ClN5O3SPurity:99.51%Color and Shape:SolidMolecular weight:469.94Ulacamten
CAS:Ulacamten is an effective inhibitor of cardiac myosin (cardiacmyosin).Formula:C21H25F2N3O3Color and Shape:SolidMolecular weight:405.44Enzastaurin
CAS:Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.Formula:C32H29N5O2Purity:100% - 99.24%Color and Shape:SolidMolecular weight:515.6BT100
BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].Purity:98%Color and Shape:Odour SolidCilengitide
CAS:Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formula:C27H40N8O7Purity:98% - 99.8%Color and Shape:SolidMolecular weight:588.66Ref: TM-T2494
1mg49.00€2mg70.00€5mg96.00€10mg160.00€25mg274.00€50mg439.00€100mg632.00€1mL*10mM (DMSO)137.00€NMS-E973
CAS:NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.Formula:C22H22N4O7Purity:99.82%Color and Shape:SolidMolecular weight:454.43Ref: TM-T6609
2mg42.00€5mg64.00€10mg97.00€25mg197.00€50mg310.00€100mg442.00€200mg622.00€1mL*10mM (DMSO)70.00€Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Formula:C30H16O8Purity:99.05% - ≥98%Color and Shape:Red-Coloured Anthraquinone-DerivativeMolecular weight:504.44Ref: TM-T6S0923
1mg57.00€5mg127.00€10mg182.00€25mg360.00€50mg532.00€100mg743.00€500mg1,510.00€1mL*10mM (DMSO)140.00€Ispinesib
CAS:Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplasticFormula:C30H33ClN4O2Purity:98% - 98.59%Color and Shape:SolidMolecular weight:517.06Ref: TM-T2103
1mg39.00€2mg50.00€5mg79.00€10mg118.00€25mg210.00€50mg339.00€100mg557.00€500mg1,216.00€1mL*10mM (DMSO)89.00€NCT-58
CAS:NCT-58 is a potent HSP90 inhibitor that blocks Akt, downregulates HER family, and induces apoptosis in HER2+ breast cancer without triggering HSR.Formula:C27H34N2O5Purity:98.75%Color and Shape:SolidMolecular weight:466.57Ref: TM-T9996
2mg46.00€5mg85.00€10mg126.00€25mg259.00€50mg415.00€100mg662.00€200mg889.00€1mL*10mM (DMSO)207.00€Trimethyloctadecylammonium bromide
CAS:Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.Formula:C21H46N·BrPurity:99.09%Color and Shape:Solid SolidMolecular weight:392.5cis-trismethoxy Resveratrol
CAS:cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.Formula:C17H18O3Purity:97.55%Color and Shape:SolidMolecular weight:270.32Vinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Formula:C45H54F2N4O8·xC4H6O6Purity:98%Color and Shape:SolidMolecular weight:967.02Ref: TM-T6722
2mgTo inquire5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire1mL*10mM (DMSO)To inquireNU074381b
NU074381b (compound 5b) is an effective inhibitor of S100A4, disrupting the formation of the S100A4-NMII complex with an IC50 value of 0.48 µM. Additionally, it inhibits cell proliferation and migration.Formula:C23H25ClN2O2Color and Shape:SolidMolecular weight:396.91NDNA3
NDNA3 (compound 14) selectively inhibits Hsp90α with an IC50 of 0.51 μM, demonstrating low membrane permeability and minimal toxicity to Ovcar-8 and MCF-10AFormula:C28H32N2O3SPurity:98%Color and Shape:SolidMolecular weight:476.63CMPF
CAS:CMPF is a microtubule protein inhibitor that can be used to study tumors.Formula:C12H16O5Purity:99.5%Color and Shape:SolidMolecular weight:240.25HSF1A
CAS:HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.Formula:C21H19N3O2S2Purity:98.89%Color and Shape:SolidMolecular weight:409.52Ref: TM-T4125
1mg55.00€2mg88.00€5mg139.00€10mg207.00€25mg462.00€50mg677.00€100mg938.00€1mL*10mM (DMSO)130.00€Olverembatinib dimesylate
CAS:Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).Formula:C29H27F3N6O·2CH4O3SPurity:100% - 99.81%Color and Shape:SolidMolecular weight:724.77Ref: TM-T2429
1mg39.00€2mg51.00€5mg84.00€10mg119.00€25mg229.00€50mg319.00€100mg474.00€1mL*10mM (DMSO)120.00€VnP-16
VnP-16 enhances bone formation by stimulating the differentiation and activity of osteoblasts via direct β1 integrin engagement, which subsequently activatesFormula:C82H112N20O17Purity:98%Color and Shape:SolidMolecular weight:1649.89BCR-ABL-IN-7
CAS:BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.Formula:C19H16FN3O3SPurity:98.28%Color and Shape:SolidMolecular weight:385.41PKCε Inhibitor Peptide acetate
PKCε Inhibitor Peptide acetate is a selective PKCε inhibitor containing the site for its specific receptor for activated C kinase (RACK).Formula:C39H69N9O15Purity:98.93%Color and Shape:SolidMolecular weight:904.02Ref: TM-T35827L
1mg65.00€2mg94.00€5mg116.00€10mg187.00€25mg314.00€50mg452.00€100mg620.00€200mg835.00€OSIP-486823
CAS:OSIP-486823(CP248) is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.Formula:C29H28FNO4Purity:98.59%Color and Shape:SolidMolecular weight:473.54Valecobulin hydrochloride
CAS:Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.Formula:C26H29ClN6O5SPurity:98.63%Color and Shape:SolidMolecular weight:573.06Ref: TM-T13278
1mg88.00€5mg170.00€10mg259.00€25mg429.00€50mg605.00€100mg815.00€200mg1,093.00€1mL*10mM (DMSO)207.00€Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98.59% - 99.19%Color and Shape:SolidMolecular weight:292.35Ref: TM-T4048
1mg48.00€5mg78.00€10mg97.00€25mg188.00€50mg311.00€100mg502.00€500mg1,074.00€1mL*10mM (DMSO)87.00€HB-3-20
HB-3-20 induces the degradation of integrin αVβ5 on the cell surface. Transglutaminase 2 (TG2) specifically interacts with HB-3-20, exhibiting a catalytic efficiency (kcat/KM) of 0.16 μM^-1min^-1.Formula:C69H102N20O20Color and Shape:SolidMolecular weight:1531.67Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formula:C26H29Cl2N5O3Purity:98.98% - 99.9%Color and Shape:Yellowish-Orange Or Pink To Brownish Solid Solid PowderMolecular weight:530.45AC 7739
CAS:AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.Formula:C18H22ClNO4Purity:100% - 99.38%Color and Shape:SoildMolecular weight:351.83Decursinol angelate
CAS:Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.Formula:C19H20O5Purity:99.93%Color and Shape:SolidMolecular weight:328.36(S)-Monastrol
CAS:Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98%Color and Shape:SolidMolecular weight:292.35Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formula:C14H11N3O3SPurity:98% - 99.91%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:301.32Ref: TM-T2802
5mg37.00€10mg55.00€25mg99.00€50mg168.00€100mg283.00€200mg420.00€500mg682.00€1mL*10mM (DMSO)40.00€R59949
CAS:R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Formula:C28H25F2N3OSPurity:97.04%Color and Shape:SolidMolecular weight:489.58Ref: TM-T26019
1mg47.00€5mg92.00€10mg145.00€25mg298.00€50mg465.00€100mg702.00€200mg938.00€1mL*10mM (DMSO)96.00€BCR-ABL-IN-10
BCR-ABL-IN-10 (compound B4) is a covalent BCR-ABL inhibitor featuring an arylvinylsulfonate (AVS) moiety, demonstrating an IC50 of 43.1 nM against ABL kinase. It forms a covalent and stable adduct with ABL kinase, enabling the sustained inhibition of intrinsic BCR-ABL activity. This compound is utilized in the study of chronic myeloid leukemia (CML).Formula:C24H22N4O5SColor and Shape:SolidMolecular weight:478.52PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.Formula:C78H132N30O18Purity:98.78%Color and Shape:SolidMolecular weight:1778.10Myoseverin
CAS:Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.Formula:C24H28N6O2Purity:99.25%Color and Shape:SolidMolecular weight:432.52Ref: TM-T21632
5mg35.00€10mg52.00€25mg101.00€50mg170.00€100mg255.00€200mg374.00€1mL*10mM (DMSO)38.00€Etaracizumab
CAS:Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.Purity:>95% - >95%Color and Shape:LiquidMolecular weight:144.3 (kDa)Carotegrast methyl
CAS:Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Formula:C28H26Cl2N4O5Purity:99.40%Color and Shape:SolidMolecular weight:569.44Ref: TM-T30751
10g9,508.00€1mg74.00€5mg160.00€10mg264.00€25mg528.00€50mg785.00€100mg1,130.00€200mg1,549.00€1mL*10mM (DMSO)170.00€AZ3146
CAS:AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.Formula:C24H32N6O3Purity:100% - 97.84%Color and Shape:SolidMolecular weight:452.55GNF-2
CAS:GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.Formula:C18H13F3N4O2Purity:98.17% - ≥95%Color and Shape:SolidMolecular weight:374.32αvβ6 integrin inhibitor 2
CAS:αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.Formula:C21H30N4O3Purity:98%Color and Shape:SolidMolecular weight:386.49Corosolic acid
CAS:Corosolic acid inhibits angiogenesis, suppresses FAK, fights various cancers, induces apoptosis, and degrades β-catenin.Formula:C30H48O4Purity:99.46% - 99.88%Color and Shape:Fine-Brown Yellow PowderMolecular weight:472.7Hsp90-IN-38
CAS:Hsp90-IN-38 (compound 20m) is an inhibitor of HSP90 (heat shock protein). It demonstrates a strong binding affinity to HSP90 with a Kd of 87 nM. The compound inhibits ATPase activity with an IC50 of 0.13 μM. Hsp90-IN-38 also shows inhibitory effects on HCT116, MCF-7, SKBr3, K562, and A549 cells with IC50 values of 0.187, 0.072, 0.105, 0.403, and 0.031 μM, respectively.Formula:C28H35N3O5Color and Shape:SolidMolecular weight:493.595OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formula:C30H30F3N5OPurity:98.03%Color and Shape:SolidMolecular weight:533.59Ref: TM-T5485
1mg97.00€2mg144.00€5mg235.00€10mg378.00€25mg647.00€50mg920.00€100mg1,225.00€500mg2,498.00€1mL*10mM (DMSO)306.00€Aβ-IN-1 TFA
Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.Formula:C37H50F3NO2Purity:100%Color and Shape:SoildMolecular weight:597.79SNX2112
CAS:SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.Formula:C23H27F3N4O3Purity:98.9% - 99.46%Color and Shape:SolidMolecular weight:464.48Ref: TM-T6305
1mg40.00€5mg85.00€10mg127.00€25mg220.00€50mg334.00€100mg477.00€200mg662.00€1mL*10mM (DMSO)87.00€CCT251236
CAS:CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.Formula:C32H32N4O5Purity:98.82% - 99.89%Color and Shape:SolidMolecular weight:552.62Ref: TM-T14905
1mg39.00€5mg116.00€10mg221.00€25mg457.00€50mg733.00€100mg1,111.00€200mg1,501.00€1mL*10mM (DMSO)144.00€Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Formula:C14H19Cl2N3O2SPurity:99.54%Color and Shape:White Crystalline SolidMolecular weight:364.29Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formula:C26H18ClN3O2Purity:98.40%Color and Shape:SolidMolecular weight:439.89Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)Formula:C20H13N3O2Purity:98.83%Color and Shape:Dark Red SolidMolecular weight:327.34Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formula:C27H41N9O7Purity:100% - 99.83%Color and Shape:SolidMolecular weight:603.67Arg-Gly-Asp-Ser
CAS:Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Formula:C15H27N7O8Purity:98.29%Color and Shape:SolidMolecular weight:433.421,2-Dimyristoyl-sn-glycerol
CAS:1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..Formula:C31H60O5Purity:99.49%Color and Shape:White Powder With LumpsMolecular weight:512.81PD180970
CAS:PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.Formula:C21H15Cl2FN4OPurity:98.47%Color and Shape:SolidMolecular weight:429.27Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
CAS:Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand.Formula:C22H35N9O9Purity:98%Color and Shape:SolidMolecular weight:569.57PF-06651481-00
CAS:PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.Formula:C26H29Cl2N5O3Purity:97.57%Color and Shape:SolidMolecular weight:530.45SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formula:C15H14ClN3OSPurity:98%Color and Shape:SolidMolecular weight:319.81PLN-1474
CAS:PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Formula:C24H37N3O4Purity:99.25%Color and Shape:SoildMolecular weight:431.57Ref: TM-T60101
1mg52.00€5mg111.00€10mg180.00€25mg305.00€50mg439.00€100mg612.00€1mL*10mM (DMSO)124.00€Cercosporin
CAS:Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).Formula:C29H26O10Purity:98%Color and Shape:SolidMolecular weight:534.51N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formula:C28H29N7OPurity:98.60%Color and Shape:Off-White To Pale-Yellow SolidMolecular weight:479.58Ref: TM-T11641
1mg92.00€5mg170.00€10mg319.00€25mg540.00€50mg777.00€100mg1,074.00€1mL*10mM (DMSO)178.00€Geldanamycin
CAS:Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.Formula:C29H40N2O9Purity:98.83% - 99.27%Color and Shape:Yellow To Orange PowderMolecular weight:560.64MAP4343
CAS:Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Formula:C22H34O2Purity:99.32%Color and Shape:SolidMolecular weight:330.5E7820
CAS:E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Formula:C17H12N4O2SPurity:98.31% - 99.11%Color and Shape:SolidMolecular weight:336.37Ref: TM-T4435
1mg35.00€2mg52.00€5mg69.00€10mg88.00€25mg144.00€50mg210.00€100mg339.00€200mg502.00€1mL*10mM (DMSO)85.00€Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formula:C14H19Cl2N3O2SPurity:99.64%Color and Shape:White Crystalline SolidMolecular weight:364.29Ref: TM-T7501
2mg40.00€5mg52.00€10mg90.00€25mg138.00€50mg197.00€100mg293.00€200mg408.00€1mL*10mM (DMSO)66.00€FAK-IN-21
CAS:FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.Formula:C22H22F2N8O3SColor and Shape:SolidMolecular weight:516.52KIF18A-IN-2
CAS:KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.Formula:C25H34N4O5S2Purity:99.05%Color and Shape:SolidMolecular weight:534.69Ref: TM-T60026
1mg74.00€5mg172.00€10mg245.00€25mg383.00€50mg507.00€100mg672.00€200mg910.00€1mL*10mM (DMSO)202.00€HSP70-IN-1
CAS:HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).Formula:C24H28N6O2SPurity:100%Color and Shape:SolidMolecular weight:464.58Ref: TM-T3487
1mg96.00€5mg227.00€10mg354.00€25mg620.00€50mg847.00€100mg1,169.00€1mL*10mM (DMSO)230.00€ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formula:C18H17N3O4SPurity:98.84% - 99.50%Color and Shape:SolidMolecular weight:371.41AKE-72
CAS:AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.Formula:C30H29F3N6OPurity:98.3%Color and Shape:SoildMolecular weight:546.59Radotinib
CAS:Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notablyFormula:C27H21F3N8OPurity:99.13% - 99.97%Color and Shape:SolidMolecular weight:530.5Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Formula:C14H11NO4Purity:98.67% - 99.03%Color and Shape:SolidMolecular weight:257.24Ref: TM-T10860
2mg47.00€5mg70.00€10mg107.00€25mg216.00€50mg350.00€100mg542.00€200mg778.00€500mg1,169.00€1mL*10mM (DMSO)70.00€CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurity:99.81%Color and Shape:SolidMolecular weight:355.82Ref: TM-T14943
1mg35.00€2mg48.00€5mg74.00€10mg97.00€25mg187.00€50mg331.00€100mg547.00€1mL*10mM (DMSO)82.00€D-64131
CAS:D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.Formula:C16H13NO2Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:251.28PKCε (85-92)
CAS:PKCε (85-92) is a biologically active peptide that functions as a specific activator of ε-PKC and induces MARCKS phosphorylation in wild-type cells, but doesFormula:C39H54N10O14Purity:98%Color and Shape:SolidMolecular weight:886.9Schaftoside
CAS:Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.Formula:C26H28O14Purity:100% - 99.32%Color and Shape:SolidMolecular weight:564.49Ref: TM-T3898
1mg42.00€5mg85.00€10mg111.00€25mg210.00€50mg311.00€100mg467.00€200mg653.00€1mL*10mM (DMSO)95.00€FAK-IN-12
FAK-IN-12 (Compound 12S) is a selective FAK inhibitor with an IC50 of 47 nM.Purity:98%Color and Shape:Odour SolidTR-14035
CAS:TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formula:C24H21Cl2NO5Purity:98.98%Color and Shape:SolidMolecular weight:474.33Ref: TM-T5310
1mg52.00€5mg105.00€10mg170.00€25mg298.00€50mg430.00€100mg605.00€200mg815.00€1mL*10mM (DMSO)111.00€Go 6983
CAS:Go 6983 is a pan-PKC inhibitor targeting PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, exhibiting IC50 values of 7 nM, 7 nM, 6 nM, 10 nM, and 60 nM, respectively.Formula:C26H26N4O3Purity:98.41% - 99.04%Color and Shape:SolidMolecular weight:442.51Ref: TM-T6313
1mg43.00€2mg55.00€5mg84.00€10mg126.00€25mg245.00€50mg388.00€100mg563.00€1mL*10mM (DMSO)88.00€KHS 101
CAS:KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.Formula:C18H21N5SPurity:98.00%Color and Shape:SolidMolecular weight:339.46AKT-IN-18
AKT-IN-18, an Akt inhibitor, demonstrates an IC50 value of 69.45 μM in A549 cells, effectively impeding Akt activity.Formula:C19H14ClN5O2SPurity:98%Color and Shape:SolidMolecular weight:411.864-Isopropoxybenzoic acid
CAS:4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.Formula:C10H12O3Purity:98.58%Color and Shape:White To Off-White PowderMolecular weight:180.2
