Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
CAS:Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand.Formula:C22H35N9O9Purity:98%Color and Shape:SolidMolecular weight:569.57PF-06651481-00
CAS:PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.Formula:C26H29Cl2N5O3Purity:97.57%Color and Shape:SolidMolecular weight:530.45SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Formula:C15H14ClN3OSPurity:98%Color and Shape:SolidMolecular weight:319.81PLN-1474
CAS:PLN-1474 is a potent αVβ1 inhibitor with IC50 < 50 nM.Formula:C24H37N3O4Purity:99.25%Color and Shape:SoildMolecular weight:431.57Ref: TM-T60101
1mg52.00€5mg111.00€10mg180.00€25mg305.00€50mg439.00€100mg612.00€1mL*10mM (DMSO)124.00€Cercosporin
CAS:Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).Formula:C29H26O10Purity:98%Color and Shape:SolidMolecular weight:534.51N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formula:C28H29N7OPurity:98.60%Color and Shape:Off-White To Pale-Yellow SolidMolecular weight:479.58Ref: TM-T11641
1mg92.00€5mg170.00€10mg319.00€25mg540.00€50mg777.00€100mg1,074.00€1mL*10mM (DMSO)178.00€Geldanamycin
CAS:Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.Formula:C29H40N2O9Purity:98.83% - 99.27%Color and Shape:Yellow To Orange PowderMolecular weight:560.64MAP4343
CAS:Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.Formula:C22H34O2Purity:99.32%Color and Shape:SolidMolecular weight:330.5E7820
CAS:E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Formula:C17H12N4O2SPurity:98.31% - 99.11%Color and Shape:SolidMolecular weight:336.37Ref: TM-T4435
1mg35.00€2mg52.00€5mg69.00€10mg88.00€25mg144.00€50mg210.00€100mg339.00€200mg502.00€1mL*10mM (DMSO)85.00€Iso-H7 dihydrochloride
CAS:Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.Formula:C14H19Cl2N3O2SPurity:99.64%Color and Shape:White Crystalline SolidMolecular weight:364.29Ref: TM-T7501
2mg40.00€5mg52.00€10mg90.00€25mg138.00€50mg197.00€100mg293.00€200mg408.00€1mL*10mM (DMSO)66.00€FAK-IN-21
CAS:FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.Formula:C22H22F2N8O3SColor and Shape:SolidMolecular weight:516.52KIF18A-IN-2
CAS:KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.Formula:C25H34N4O5S2Purity:99.05%Color and Shape:SolidMolecular weight:534.69Ref: TM-T60026
1mg74.00€5mg172.00€10mg245.00€25mg383.00€50mg507.00€100mg672.00€200mg910.00€1mL*10mM (DMSO)202.00€HSP70-IN-1
CAS:HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).Formula:C24H28N6O2SPurity:100%Color and Shape:SolidMolecular weight:464.58Ref: TM-T3487
1mg96.00€5mg227.00€10mg354.00€25mg620.00€50mg847.00€100mg1,169.00€1mL*10mM (DMSO)230.00€ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Formula:C18H17N3O4SPurity:98.84% - 99.50%Color and Shape:SolidMolecular weight:371.41AKE-72
CAS:AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.Formula:C30H29F3N6OPurity:98.3%Color and Shape:SoildMolecular weight:546.59Radotinib
CAS:Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notablyFormula:C27H21F3N8OPurity:99.13% - 99.97%Color and Shape:SolidMolecular weight:530.5Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Formula:C14H11NO4Purity:98.67% - 99.03%Color and Shape:SolidMolecular weight:257.24Ref: TM-T10860
2mg47.00€5mg70.00€10mg107.00€25mg216.00€50mg350.00€100mg542.00€200mg778.00€500mg1,169.00€1mL*10mM (DMSO)70.00€CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurity:99.81%Color and Shape:SolidMolecular weight:355.82Ref: TM-T14943
1mg35.00€2mg48.00€5mg74.00€10mg97.00€25mg187.00€50mg331.00€100mg547.00€1mL*10mM (DMSO)82.00€D-64131
CAS:D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.Formula:C16H13NO2Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:251.28PKCε (85-92)
CAS:PKCε (85-92) is a biologically active peptide that functions as a specific activator of ε-PKC and induces MARCKS phosphorylation in wild-type cells, but doesFormula:C39H54N10O14Purity:98%Color and Shape:SolidMolecular weight:886.9
