Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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FRAX486
CAS:FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Formula:C25H23Cl2FN6OPurity:98.81%Color and Shape:SolidMolecular weight:513.39AKT-IN-26
CAS:AKT-IN-26 (Compound 453) is an AKT inhibitor that binds to the Pleckstrin Homology (PH) domain of AKT. It is useful for research related to cell proliferation and cancer involving the AKT pathway.Formula:C21H17N5O4SColor and Shape:SolidMolecular weight:435.456JG-231
CAS:JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.Formula:C22H18BrCl2N3OS4Purity:99.21%Color and Shape:SolidMolecular weight:619.47TN-16
CAS:TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)Formula:C19H18N2O2Purity:99.54%Color and Shape:SolidMolecular weight:306.36LXW7
CAS:LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Formula:C29H48N12O12S2Purity:100%Color and Shape:SolidMolecular weight:820.89Batatasin III
CAS:Batatasin III inhibits cancer migration and invasion by suppressing epithelial to mesenchymal transition and FAK-AKT signals and possesses anti-cancerFormula:C15H16O3Purity:99.16%Color and Shape:SolidMolecular weight:244.29HM03
CAS:HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.Formula:C26H27ClN4O2Purity:97.15%Color and Shape:SolidMolecular weight:462.97AT7867
CAS:AT7867 inhibits Akt1/2/3 & p70S6K/PKA (IC50: 32/17/47 nM & 85/20 nM), minimal effect beyond AGC kinases.Formula:C20H20ClN3Purity:99.63%Color and Shape:SolidMolecular weight:337.85Ref: TM-T6304
2mg44.00€5mg65.00€10mg86.00€25mg135.00€50mg210.00€100mg313.00€200mg452.00€1mL*10mM (DMSO)65.00€2-Methylbutyrylcarnitine chloride
2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.Formula:C12H24ClNO4Color and Shape:SolidMolecular weight:281.78Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.34Valategrast hydrochloride
CAS:Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.Formula:C30H33Cl4N3O4Purity:98%Color and Shape:SolidMolecular weight:641.41Irigenin
CAS:Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormula:C18H16O8Purity:99.50% - 99.85%Color and Shape:SolidMolecular weight:360.31Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)Formula:C18H18Cl3FN4OSPurity:99.96%Color and Shape:SolidMolecular weight:463.8Ref: TM-T7885
2mg52.00€5mg74.00€10mg95.00€25mg163.00€50mg253.00€100mg437.00€200mg568.00€1mL*10mM (DMSO)86.00€Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Purity:> 95% - > 95%Color and Shape:LiquidMolecular weight:144.22 kDaDolastatin 10
CAS:Dolastatin 10 (DLS 10) is a powerful peptide with antimitotic properties, effectively inhibiting tubulin polymerization.Formula:C42H68N6O6SPurity:99.55%Color and Shape:SolidMolecular weight:785.09Shepherdin 79-87 acetate
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.Formula:C43H68N12O14SPurity:98.08%Color and Shape:SolidMolecular weight:1009.14G-5555
CAS:G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).Formula:C25H25ClN6O3Purity:99.76% - 99.87%Color and Shape:SolidMolecular weight:492.96Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formula:C29H29F3N8OPurity:99.52% - 99.95%Color and Shape:SolidMolecular weight:562.59Ref: TM-T4320
1mg35.00€5mg66.00€10mg87.00€25mg127.00€50mg163.00€100mg273.00€200mg409.00€500mg677.00€1mL*10mM (DMSO)87.00€Betamethasone 17-benzoate
CAS:Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of recurrent aphothous ulcers (RAU).Formula:C29H33FO6Purity:98%Color and Shape:SolidMolecular weight:496.57EC 144
CAS:EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.Formula:C21H24ClN5O2Color and Shape:SolidMolecular weight:413.9
