Deuterated Compounds

H-ADAQHATPPKKKRKVEDPKDF-OH peptide, which can act as a substrate of Protein Kinase P34 (cd2). The peptide is supplied as a trifluoroacetate salt.

Applications Labelled NEMA (N525950). One of the N-nitrosamines found in the water sources and water treatment process. Carcinogen. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Raska, I., et al.: Bioorg. Med. Chem., 13, 6830 (2005), Puzyn, T., et al.: Environ. Sci. Technol., 42, 5189 (2008),

Applications Labelled analogue of Hydrocinnamic Acid, a cinnamic acid derivative used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid. References Migliaccio, A., et al.: Blood, 76, 1150 (1990); McDonagh, K., et al.: J. Biol. Chem., 266, 11965 (1991);

Applications Hexadecanoic-9,9-d2 Acid (CAS# 272442-14-5) is a useful isotopically labeled research compound.

Stability No Data Avaialble Applications 2-Chlorophenol (Ring-D4, 99%) was an analyte in a study looking to optimize ultrasonic extraction for efficient detection of polycyclic aromatic hydrocarbons (PAHs) in soil. References Stankov Jovanovic, V., et al.: Anal. Lett., 50, 2491 (2017)

Applications 2’,3’,5’-Tri-O-benzoyl Xanthine-13C5 is an intermediate used in the synthesis of Xanthosine-13C5 (X742102), which is the labeled analogue of Xanthosine (X742100), the deamination product of Guanosine. It is also a potential biomarker for detecting radiation exposure. References Magasanik, B, et al.: J. Bio. Chem., 206, 83 (1954);

Applications 2-tert-Butyldimethylsilyloxyethanol-d4 (cas# 764650-43-3) is a compound useful in organic synthesis. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Reproduction of Sindbis virus strains sensitive and resistant to 1-adamantanecarboxamide. References Erice, A., et al.: N. Engl. J. Med., 320, 289 (1989), Andronova, V.L., et al.: Bull. Exper. Bio. Med., 129, 74 (2000).

Applications 1-Chloropropane-1,1-d2 (CAS# 125640-23-5) is a useful isotopically labeled research compound.

Please enquire for more information about Pyruvic Acid-13C Ethyl Ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Labelled Bis(2-ethylhexyl)phthalate. Bis(2-ethylhexyl) Phthalate plasticizer is used to impart softness and flexibility to PVC products. References Heindel, J., et al.: Toxicol. Appl. Pharmacol., 115, 116 (1992), Kasahara, E., et al.: Biochem. J., 365, 849 (2002), Lee, B., et al.: J. Toxicol. Environ. Health, 70, 1365 (2007),

Applications Isotope labelled wittig reagent.

Applications 5’-Deoxy-5’-iodo-5-fluorouridine-13C,15N2 , >95% is a compound useful in organic synthesis.

Applications Hexadecanoic Acid-1,2-13C2 (CAS# 86683-25-2) is a useful isotopically labeled research compound.

Applications 2-Hydroxyacetophenone-d7 (cas# 1189865-36-8) is a compound useful in organic synthesis.

Applications Methacrylic Acid-d6 (CAS# 92140-95-9) is a useful isotopically labeled research compound.

Applications N-Acetylethylene Urea-d4 (cas# 1189701-94-7) is a compound useful in organic synthesis.

Applications Dimethyl Hexanedioate-2,2,5,5-d4 (CAS# 76785-05-2) is a useful isotopically labeled research compound.

Applications 2-Naphthol-d7 has been used as a reactant for the preparation of stable isotope-labeled internal standards of PAH metabolites from urine of smokers and nonsmokers. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Jacob, P. III, et. al.: Anal. Chem., 79, 587 (2007)

Applications 1-Bromohexane-2,2,3,3,4,4,5,5,6,6,6-d11 (CAS# 2159-17-3) is a useful isotopically labeled research compound.

Applications Wittig reagent

Applications Labelled Dimethyl Phthalate (D477975). It is used as insect repellent. References Iselin, B., et al.: Helv. Chim. Acta., 40, 373 (1957),

Applications 2'-Deoxyuridine-5,6-d2 (CAS# 40632-23-3) is a useful isotopically labeled research compound.

Applications (4-n-Nonylphenoxy)acetic-alpha,alpha-d2 Acid (CAS# 1219798-75-0) is a useful isotopically labeled research compound.

Stability Hygroscopic Applications Decanoyl-L-carnitine-d3 Chloride is the isotope labelled analog of Decanoyl-L-carnitine Chloride (D212580); a metabolite of L-Carnitine (C184110) which is an essential cofactor of fatty acid metabolism. Also required for the transport of fatty acids through the inner mitochondrial membrane. References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978); Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001); Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002); Karlic, H., et al.: Nutrition, 20, 709 (2004)

Applications 2-(2-Propynyloxy)tetrahydropyran-13C3 is an intermediate in the synthesis of N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine-13C4 (A173713). N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine-13C4 is labelled N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine (A173710), which is a metabolite of butadiene. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Heavner, D., et al.: J. Pharm. Biomed. Anal., 40, 928 (2006); Carmella, S., et al.: Chem. Res. Toxicol., 22, 734 (2009)

Applications Uracil-d4 is the labelled compound form of Uracil (U801000) which is a nitrogenous base on RNA nucleosides. References Seth, P., et al.: J. Med. Chem., 53, 8309 (2010); Cui, H., et al.: Eur. J. Med. Chem., 45, 5140 (2010)

Please enquire for more information about 2-[(2-Methoxyphenoxy)methyl]oxirane-d3 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 1,2-Dihydrodesonide-d3 is the labeled analogue of 1,2-Dihydrodesonide (D448170), a reactant in the synthesis of 21-substituted corticosteroids which are used as topical antiinflammatory agents. References Mitsukuchi, M., et. al.: Chem. Pharm. Bull, 37, 1795 (1989)

1-Iodobutane-D9 is a linear, stable molecule with a rotational frequency of 2.7 GHz. The infrared and Raman spectra show that the molecule has one equivalent iodine atom, which is in the 9 position on the chain. The 1-iodobutane-D9 molecule has a triple bond and an average rotational constant of 2.25 x 10^6 Hz and vibrational frequencies of 3.2 x 10^14 Hz for the butyl group.

Applications 4-Toluidine-d7 (Major) (cas# 68693-08-3) is a compound useful in organic synthesis. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Ethyl 2-Oxo-4-phenylbutyrate-d5 (cas# 1189911-53-2) is a compound useful in organic synthesis.

Applications Labelled nitro substituted piperazine.

Applications Styrene-alpha,beta,beta-d3 (CAS# 3814-93-5) is a useful isotopically labeled research compound.

Applications A labelled reactant used in the preparation of inhibitors for treatment of neurodegenerative diseases.

Applications Eicosapentaenoyl Ethanolamide-d4 is labelled Eicosapentaenoyl Ethanolamide (E477960) which inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes. References Lucanic, M., et al.: Nature, 473, 226 (2011)

Applications 2-(3,4-Dihydroxyphenyl)ethyl-1-13C-amine HCl (CAS# 335081-04-4) is a useful isotopically labeled research compound.

Applications Isotope labelled 1-Pentene, used in the synthesis of iminosugars such as d-xylitol and l-arabinitol. Also usd in the synthesis of hydrazones of substituted salicylaldehydes. E3 References Biela, A. et al.: Tetrahedron, 69, 3348 (2013); Ding, S. et al.: J. Coord. Chem., 66, 2023 (2013);

Applications 1-(4-Hydroxy-3-methoxyphenyl)-1-propanone-d3 is labelled 1-(4-Hydroxy-3-methoxyphenyl)-1-propanone (H947600) which is a derivative of Guaiacol, a precursor to various flavorants, such as eugenol and vanillin. References Allen, C., et al.: Org. Synth., 3, 418 (1955); Esposito, L., et al.: Kirk-Othmer Encyclopedia of Chemical Technology, 4th edition, 24, 812 (1997)

Applications DL-Leucine-d7 (iso-propyl-d7) (CAS# 259225-40-6) is a useful isotopically labeled research compound.

Applications A labelled isomer of dichloropropanol; shows metabolite toxicity. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Omura, M., et al.: Bull. Environ. Contam. Toxicol., 55, 1 (1995),

Applications n-Octylbenzene-2,3,4,5,6-d5 (CAS# 1219799-23-1) is a useful isotopically labeled research compound.

Applications 6-Chloro-1-hexyl-3,3,4,4,5,5-d6 Alcohol (CAS# 1219794-83-8) is a useful isotopically labeled research compound.

Applications Isotope labelled 2-Ethyl-1-hexanol is used in the preparation of succinate-based plasticizers for replacing phthalate plasticizers. Also used in the preparation of polymeric plasticizers. References Stuart, A. et al.: Eur. Polym. J. 49, 2785 (2013); Braslau, R. et al.: J. Polym. Sci. Part. A. Polym. Chem., 51, 1175 (2013);

Applications Pyrimidine with the ability to form complexes with heavy metal ions. References Iltzsch, M., et al.: Biochem. Pharmacol., 48, 781 (1994),

Applications N-[2-(S)-Methyl-d3-butyryl]-4-(S)-phenylmethyl-2-oxazolidinone (cas# 1073232-99-1) is a compound useful in organic synthesis.

Applications 6-Chloro-N-(2,2-difluoroethyl)-3-pyridinemethanamine-d2 is an intermediate used in the synthesis of Flupyradifurone-d5 (F598616), which is the labeled form of Flupyradifurone (F598615), can be used as an insecticide. References Anon, IP.com J., 12, 19 (2011)

Applications m-Cresol-d8 (CAS# 302911-90-6) is a useful isotopically labeled research compound.

Acetonitrile-D3 is a compound that contains a hydroxyl group and a nitrogen atom. It is used as a diagnostic agent in kinetic data, FT-IR spectroscopy, and chemical reactions. Acetonitrile-D3 has been shown to form stable complexes with acidic molecules such as phosphoric acid. The reaction mechanism for the formation of these complexes is not yet known. This compound can be used to measure the concentration of alcohols, amines, and nitro compounds in test samples. Acetonitrile-D3 also has a deuterium isotope effect on chemical reactions, which may be due to the strength of hydrogen bonds formed between the compound and other reactants.

Applications (±)-Haloxyfop-d4 is the labeled analogue of (±)-Haloxyfop (H104040) a herbicide. References Manalil, S., et. al.: Weed Sci., 59, 210 (2011);

Applications Bunitrolol-D5 is a labelled analogue of Bunitrolol (B689440).

Please enquire for more information about 1,3-Distearoyl-2-chloropropanediol-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications A labelled methoxime derivative as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Herold, D.A., et al.: Prostaglandins, 33, 599 (1987),

Applications Isotope labelled 2-Toluidine (T536205) is a carcinogenic and toxic aromatic amine and is a potential bladder cancer risk, surmised from urine assessment and analysis (1). It is contained in hair dye, henna and dyed hair samples (2,3). Possible mutagen (4). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References 1. El-Bayoumy, K. et al.: Cancer Res. 1986 Dec;46(12 Pt 1):6064-7.2. Turesky R. et al.: Chem. Res. Toxicol. 2003 Sep;16(9):1162-73.3. Andrew, A. et al.: Int. J. Cancer. 2004 Apr 20;109(4):581-6.4. Kirkland, D. et al.: Mutat. Res. 2005 Dec 30;588(2):88-105.

Applications A deuterated intermediate in the synthesis of Carisoprodol.

Applications Labelled ε-Aminocaproic Acid. Used in the preparatiom of esters of 6-aminohexanoic acid as antibacterial agents. EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo xy peptidase, plasmin, and plasminogen activator. References Dolezal, P., et al.: Pharm. Res., 10, 1015 (1993), Vavrova, K., et al.: Curr. Med. Chem., 12, 2273 (2005), Holas, T., et al.: Bioorg. Med. Chem., 14, 7671 (2006),

Applications 2-Hydroxy-1,4-naphthoquinone-5,6,7,8-d4 is the isotope labelled analog of 2-Hydroxy-1,4-naphthoquinone (Lawsone) (H949535); the active ingredient of Lawsonia inermis (henna) leaves extract. Lawsone has potential antimicrobial activity and can be used for the detection of latent fingermarks on paper surfaces. References Tekin, V., et al.: J. Radioanal. Nucl. Ch., (2014); Rahmoun, N.M., et al.: Am. J. Med. Biol. Res., 1, 16 (2013); Jelly, R., et al.: Chem. Commun., 30, 3513 (2008)

Applications N-Acetyl-DL-alanine-3,3,3-d3 is an isotopic analog of N-Acetyl-DL-alanine (A167965), a derivative of DL-Alanine (A481400) and is used as a reagent in the synthesis of potent new agents for the treatment of epilepsy. References Conley, J.D., et al.: J. Med. Chem., 30, 567 (1987)

Applications (S)-1-Nitrosopiperidin-3-ol-d4 is an intermediate in synthesizing Ibrutinib-d4 (I124971), a labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor. References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)

Applications Ethyl-1,1-d2-methylamine (CAS# 223459-63-0) is a useful isotopically labeled research compound.

Applications Ethyl-d5-methylamine (CAS# 1219804-73-5) is a useful isotopically labeled research compound.

Applications Ethyl (±)-2-Bromopropionate-3,3,3-d3 (CAS# 1398066-14-2) is a useful isotopically labeled research compound.

Applications Secobarbital-d5 (1-methyl-d3-butyl-2,2-d2) (CAS# 1219803-94-7) is a useful isotopically labeled research compound.

Applications A labelled isotope of a toxic volatile hydrazine found in rocket fuel systems. References Oanasyuk, A.G. et al.: Vis. Nat. Tekh. Univ. KhPI, 13, 59 (2010);

Applications Octahydro-6-(phenylmethyl)-1H-Pyrrolo[3,4-b]pyridine-d4 is an isotope labelled intermediate in the synthesis of moxifoxacin (M745000), a fluorinated quinolone antibacterial. References Somisetti, N. et al.: Org. Chem. Indian J., 7, 123 (2011);