Deuterated Compounds

Applications Contact herbicide used also to produce desiccation and defoliation. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Brian, et al.: Nature, 181, 446 (1958), Gaines, T.B., et al.: Fundam. Appl. Toxicol., 7, 299 (1986),

Applications D-Alanine-3,3,3-d3-N-t-BOC (CAS# 177614-70-9) is a useful isotopically labeled research compound.

Applications Butyric-2,2-d2 Acid (CAS# 19136-92-6) is a useful isotopically labeled research compound.

Applications (±)-Phenyramidol-d4 is a muscle relaxant drug. It can also be used in analytical study of LC-MS method development on α1-acid glycoprotein-based stationary phase for resoln. and screening of enantiomers by HPLC. References Michishita, T., et al.: J Sep Sci, 33, 3627 (2010)

Applications 2-Amino-4,6-dihydroxypyrimidine-13C2 is an intermediate in the production of antimicrobial guanylsulfonamides. References Barrett, O., et al.: ChemBioChem., 7, 1882 (2006), Patel, P., et al.: Bioorg. Med. Chem. Lett., 17, 6610 (2007), Gasser, L., et al.: Environ. Sci. Technol., 41, 2445 (2007)

Applications n-Heptyl-5,5,6,6,7,7,7-d7 Alcohol (CAS# 1219804-99-5) is a useful isotopically labeled research compound.

Applications m-Toluidine-d7 (NH2) (CAS# 68408-25-3) is a useful isotopically labeled research compound. Due to the H-D reaction, this compound can be used as a mixed catalystic for its synergistic effect. References Ito, N., et.al., Synthesis, 9, 1467-1478,(2008);

Applications Sodium Formate (13c, 99%; D, 98%) (cas# 1215684-17-5) is a useful research chemical.

Applications 3-(4-Chlorophenyl)-1-isoindolinone-d4 is the isotope labelled analog of 3-(4-Chlorophenyl)-1-isoindolinone (C378535), which is an intermediate of Chlorthalidone (C427500), a diuretic and antihypertensive agent. References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966), Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972), Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985),

Applications Anticonvulsant against audiogenic convulsion. References Goeres, E., et al.: Acta Biol. Med. Ger., 23, 679 (1969)

Applications n-Undecyl-d23-amine (CAS# 1219805-57-8) is a useful isotopically labeled research compound.

Applications N-[1-(3’-Benzyloxyphenyl)ethyl]-N,N-dimethyl-d6-amine (cas# 1190006-94-0) is a compound useful in organic synthesis.

Applications 3-(N-Morpholino)propanesulfonic Acid-d15 (CAS# 1219799-30-0) is a useful isotopically labeled research compound.

Applications Ethyl-alpha,alpha-d2-benzene-d5 (CAS# 84272-90-2) is a useful isotopically labeled research compound.

Hydrazine sulfate-15N2 is a trimethylsilylated hydrazine sulfate. It is used as an intermediate for the synthesis of N-trimethylsilylhydrazines and other trimethylsilylhydrazines. The compound can also be used to prepare glutamine as it reacts with dl-glutamine to form hydroxylamine, which then reacts with hydrogen sulfide to form glutathione. Hydrazine sulfate-15N2 is mainly used as a catalyst in the production of nitric acid from ammonia and oxygen gas.

Applications Trimethyl Orthopropionate-2,2,3,3,3-d5 (CAS# 1219803-49-2) is a useful isotopically labeled research compound.

Applications Isopropyl Acetate-d10 is the isotope labelled analog of Isopropyl Acetate (I823415); a widely used chemical solvent in organic and industrial syntheses. Isopropyl Acetate is also used in the dissolution of gallstones.Environmental contaminants; Food contaminants Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Zakko, S. et al.: Gastroenterol., 113, 232 (1997); Loeser, E. et al.: J. Chromatogr. A., 1216, 3409 (2009)

Please enquire for more information about 9-Methyl-d3-adenine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Isopropylaminosulfoni-d7 Acid is an intermediate in the synthesis of Bentazon-d7 (B120583). Bentazon-d7 is deuterium labelled Bentazon (B120580), which is a herbicide. Isopropylaminosulfoni-d7 Acid is also the labeled form of Isopropylaminosulfonic Acid (I824090), which is an reactant used in the synthesis of N-Alkylsulfamic Acid Derivatives. References Ghirardello, D., et al.: Environ. Sci. Technol., 44, 9010 (2010); Frihauf, J., et al.: Weed Technol., 24, 262 (2010); Rotroff, D., et al.: Toxicol. Sci., 117, 348 (2010)

Applications Compound forms a complex with Mefenamic acid increasing its transdermal permeation properties Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Fang, L., et al.: J. Pharm. Sci., 93, 144 (2004), Gibellini, F., et al.: Biochem. J., 415, 135 (2008),

Applications 2,3-Dibromo-1-propan-1,1,2,3,3-d5-ol is a labelled analogue of 2,3-Dibromo-1-propanol (D425522), which is a metabolite of the flame retardant tris(2,3-dibromopropyl) phosphate (T775560), previously shown to be a mutagen and carcinogen in experimental animals. It is also an intermediate in synthesizing Bis(2,3-dibromopropyl) Phosphate-d10 (B426237), which an isotope labelled analog of Bis(2,3-dibromopropyl) Phosphate. Bis(2,3-dibromopropyl) Phosphate is a derivative of Tris(2,3-dibromopropyl) Phosphate, a widely used flame retardant in plastic and textiles. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Pandith, A.H., et al.: Org. Chem. Int., 17, (2010); Dixon, D., et al.: Toxicol. Pathol., 36,428 (2008);Eustis, S.L., et al.: Toxiciol. Sci., 26, 41 (1994); Elliott, W.C., et al.: Life. Sci., 7, 1107 (1983);

Applications N-Methylaniline-2,3,4,5,6-d5 is the deuterated form of N-Methylaniline (M288205). N-Methylaniline is used as an additive in gasoline because of its antiknock properties. References Liu, Li-jun, et al.: Huaxue Shiji, 37(1), 53-55, 96 (2015); Qin, Li-xia, et al.: Guangzhou Huagong, 43(8), 138-139, 148 (2015);

Applications Cyclopropyl-1-d1 Methyl-d3 Ketone (CAS# 95249-93-7) is a useful isotopically labeled research compound.

Applications Di-n-propyl-d14-amine (CAS# 345909-05-9) is a useful isotopically labeled research compound.

Applications Labelled Isohexanol (I819615). Isohexanol is used as a cosmetic compound with an antimicrobial effect especially deodorants. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Gallic Acid-d2 is the labelled analogue of Gallic acid (G188978) which is a phenolic acid with antioxidant activity. Gallic acid was found to protect human cells against oxidative damage and showed cytotoxicity against cancer cells. Gallic Acid and its esters also show antiviral and antifungal activities. References Yen, G. et al.: Food Chem., 79, 307 (2002); Chen, C. et al.: Mol. Nutrit. Food Res., 51, 962 (2007); Kratz, J. et al.: Mem. Inst. Oswaldo Cruz, 103, 437 (2008); Osborne, L. et al.: Infect. Immun., 33, 769 (1981);

Applications 4-Chlorobenzonitrile-d4 (CAS# 1219794-82-7) is a useful isotopically labeled research compound.

Please enquire for more information about 6-[(1E, 3E)-4-(4-Methoxy-2,3,6-trimethylphenyl-d3)-2-methyl-1,3-butadien-1-yl]-4-methyl-2H-pyran-2-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 3-Acetyl-d3 Rocuronium Bromide is the isotope labelled analog of 3-Acetyl Rocuronium Bromide (A187730); an impuritiy of Rocuronium Bromide (R639500) which is an aminosteroid and a competitive neuromuscular blocker. References Srinivasan, N., et al.: Oriental. J. Chem., 24, 989 (2008); Magorian, T., et al.: Anesthesiology, 79, 913 (1993); Wicks, T.C., et al.: J. Am. Assoc. Nurse Anesth., 62, 33 (1994)

Applications 2,6-Dimethylphenol-d9 (Major) (cas# 1021325-40-5) is a compound useful in organic synthesis. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Stability Hygroscopic Applications Guaiacol-beta-D-glucopyranoside-d3, is a labeled analogue of Guaiacol-beta-D-glucopyranoside (G245565), a Guaiacol Conjugate, that has shown to present in fermentation of grapes that had been exposed to bushfire smoke and can potentially yield unpalatable, smoke-affected wine. References Hayasaka, Y.m et al.: J. Arg. Food Chem., Vol. 58, Issue 4, P: 2076; 2081 (2010);

Applications 1,8-Octanedioic-d12 Acid (CAS# 169397-99-3) is a useful isotopically labeled research compound.

Applications 3-Nitroaniline acts as an azo dye used in analytical toxicity studies. 3-Nitroaniline-2,4,5,6-d4 is the labeled version. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Garner, R.C. et al.: Mut. Res., et al 44, 9 (1977);

Applications Ethyl 2,3-Dicyanopropionate-13C2 15N2, is the labeled analogue of Ethyl 2,3-Dicyanopropionate (E915950), which is an intermediate for insecticide. References Cole, L., et al.: Pestic. Biochem. Physiol., 46, 47 (1993), Cole, L., et al.: Life Sci., 56, 757 (1995), Hosie, A., et al.: Br. J. Pharmacol., 115, 909 (1995),

Oxytetracycline-d6 is a water-soluble derivative of the antibiotic oxytetracycline. It is used in the preparation of samples for mass spectrometry and other analytical methods. Oxytetracycline-d6 has shown genotoxic effects at high concentrations, but at lower concentrations, it may have antimicrobial activity. The use of oxytetracycline-d6 in wastewater treatment is being explored as a possible means to control microbial populations in wastewater.

Applications 2-Ethyl 13C6-toluene is a labelled aromatic standard. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 3-Hydroxyquinoline-d6 is labelled 3-Hydroxyquinoline (H953140) which is a chemical reagent used in the preparation cyclic peptides with an antitumor functionality. Quinoline derivative as a result of the metabolism by cytochrome P 450. References Riego, E. et al.: Tetrahedron, 61, 1407 (2005); Kanou, M. et al.: Fund. Clin. Pharmacol., 16, 513 (2002)

Applications Benzimidazole-4,5,6,7-d4 (CAS# 64531-29-9) is a useful isotopically labeled research compound.

Stability Hygroscopic Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),

Applications A labelled chloropropanol which shows toxic effects. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Andersen, H., et al.: Toxicology, 136, 67 (1999), Fry, J., et al.: Food Chem. Toxicol., 37, 351 (1999), Garle, M., et al.: Xenobiotica, 29, 533 (1999),

Applications Bis(3-methyl-2-pentyl) Phthalate-d4, is the labeled analogue of Bis(3-methyl-2-pentyl) Phthalate (B486015), used as a plasticizer to impart softness and flexibility to PVC products. References Pierson, J. F., et al.: Angewandte Makromolekulare Chemie, 38, 167 (1979); Kaya, T., et al.: Chem. Res. Toxic., 19 (8), 999 (2006); Matter, H., et al.: Bioorg. Med. Chem., 20 (18), 5352 (2012);

Please enquire for more information about ([ring-D5]Phe8)-Angiotensin II acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 2-Chloroethanol is used in the preparation of TTFTT (tetrathiafulvalene-2,3,6,7-tetrathiolate) and important building block in TTF syntheis. In addition, it is used in the synthesis of vinyltriazoles. This is the labeled analog. Dangerous Goods Info This compound is forbidden to ship by air under IATA regulations. References Svenstrup, N. et al.: Synthesis, 8, 809 (1994); Thibault, R. et al.: J. Am. Chem. Soc., 128, 12084 (2006);

Applications Isotope labelled N-1-Naphthylethylenediamine Dihydrochloride, is an organic building block used for the chemical synthesis. It can also be used as highly selective organic fluorescent probe for azide ion. References Sahana, A., et al.: Analyst , 137, 1544 (2012);

Applications n-Heptylbenzene-2,3,4,5,6-d5 (CAS# 1219799-19-5) is a useful isotopically labeled research compound.

Applications Labelled Cortisol (H714615). Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. References Hechter, O., et al.: Arch. Biochem. Biophys., 25, 457 (1950), Colingsworth, D.R., et al.: J. Biol. Chem., 203, 807 (1953), Florey, K., et al.: Anal. Profiles Drug Subs., 12, 277 (1983),

Applications 2-((Hexyl-d4)oxy)tetrahydropyran is a proposed intermediate in the synthesis of 1-Octen-3-one-D4 (O239252), a labelled analogue of 1-Octen-3-one (O239250). 1-Octen-3-one is a volatile unsaturated ketone that has a strong mushroom-like odour. 1-Octen-3-one is also a flavour component of the Agaricus bisporus mushroom and is used in a variety of food products. References Culleré, L., et al.: Anal. Chim. Acta, 563, 51 (2006); Fickert, B. & Schieberle, P.: Food/Nahrung, 42, 371 (1998); Husson, F., et al.: Proc. Biochem., 37, 177 (2001)

Applications 2-Chlorotoluene-3,4,5,6-d4 (CAS# 362049-57-8) is a useful isotopically labeled research compound.

Applications Isopropyl-d7-amine Hydrochloride is the hydrochloride analogue of Isopropyl-d7-amine (I823977), which may act as a potential protease inhibitor but also takes part in numerous organic chemical reactions such as amide synthesis. References Dam, J.H. et al.: Chem. A. Eur. J., 16, 6820 (2010); Latli, B. et al.: J Labelled. Compd. Radiopharm., 48, 447 (2005)

Applications Triclabendazole Sulfone-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic. References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)

Applications Isotope labelled N-(Phenyl)-1-napthyl Amine is a chemical reactant used in the preparation of aryl halides and diarylamines. Also forms oligomers used as hole transport for green electrophosphorescence. References Yamamoto, T. et al.: Tetrahedron Lett., 39, 2367 (1998); Zhang, S. et al.: Dyes and Pigments., 118, 1 (2015);

Applications Propargyl Alcohol-13C3 is labelled Propargyl Alcohol (P762550) which is used as a corrosion inhibitor, a metal complex solution, a solvent stabilizer and an electroplating brightener additive. It is also used as an intermediate in organic synthesis. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Zhang, T., et al.: Res. Chem. Interm. (2013); Choudhary, Y., et al.: SPE Product. Operat., 28, 268 (2013); Hed, Y., et al.: J. Mater. Chem. Mater. Bio. Med., 1, 6015 (2013)

Applications Labelled Pentaerythritol Dibromide. It is a brominated flame retardant, previously shown to be a multisite carcinogen in experimental animals. The compound is used as a fire retardant in unsaturated polyester resins, in molded products, and in rigid polyurethane foam. It shows clear evidence of carcinogenicity and genotoxicity activity. References Heddle, J., et al.: Mutat. Res., 123, 61 (1983), Hayashi, M., et al.: Food Chem. Toxicol., 26, 485 (1988), Myhr, B., et al.: Environ. Mol. Mutagen., 18, 51 (1991), LeBoeuf, R., et al.: Mutat. Res., 356, 85 (1996),

Applications 3,4-Dichlorobenzoic-d3 Acid (CAS# 350818-53-0) is a useful isotopically labeled research compound.

Applications 3-Bromopyridine-d4 is the isotope labelled analog of 3-Bromopyridine (B686740). Pyridine as novel substrate for regioselective oxygenation with aromatic peroxygenase from Agrocybe aegerita. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Colby, J., et al.: Biochem. J., 165, 395 (1977), Damani, L., et al.: Xenobiotica, 12, 527 (1982), Balzarini, J., et al.: J. Antimicrob. Chemother., 55, 135 (2005),

Applications Glyceryl Tri(hexadecanoate-16,16,16-d3) (CAS# 285979-78-4) is a useful isotopically labeled research compound.

Applications Strobilurin fungicide; inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Agricultural fungicide. Used in Pesticide detection. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),

Please enquire for more information about Cromoglicic acid D5 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Trimethyl-d9-sulfonium Iodide (CAS# 106776-17-4) is a useful isotopically labeled research compound.

Applications Linagliptin-d3 is the isotope labelled analogue of a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);

Applications Lombazole-d9 is deuterium labelled form of Lombazole (L470205), which is imidazole based antimicrobial agent with some antifungal activity. References Barug, D., De Groot, K.: Antimicrob. Agents Chemother., 28, 643 (1985); Barug, D., et al.: Antimicrob. Agents Chemother., 30, 238 (1986);