Organic Halides

Applications 1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone is a useful synthetic intermediate in the synthesis of Prasugrel (P701150, HCl); an antiplatelet agent. References Wiviott, S.D., et al.: Circulation, 116, 2923 (2007); Xu, X., et al. Faming Zhuanli Shenqing. CN 102718642 A 20121010. Oct 10, 2012; Wang, G., et al. Faming Zhuanli Shenqing. CN 101402556 A 20090408. Apr 8, 2009

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2-(2-Fluoro-4-Hydroxy-5-Methoxyphenyl)Acetic Acid is a selective inhibitor of catecholamine uptake, which is an important step in the production of dopamine. 2-(2-Fluoro-4-Hydroxy-5-Methoxyphenyl)Acetic Acid prevents the accumulation of dopamine and thus inhibits protein synthesis. It has been shown to decrease blood pressure and improve cardiac function. This drug is also used for diagnosis, as it can be detected in blood samples through positron emission tomography (PET).

(R)-N-Methyl-3-(1-naphthoxy)-3-(2-thienyl)propylamine hydrochloride is a nonsteroidal anti-inflammatory drug that has been shown to be effective for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and chronic low back pain. This drug can also be used for other inflammatory conditions such as psoriasis and Crohn's disease. The mechanism of action of (R)-N-Methyl-3-(1-naphthoxy)-3-(2-thienyl)propylamine hydrochloride is not fully understood. It may work by blocking the synthesis of prostaglandins in the body. This drug is metabolized in the liver to its active form, which binds to cyclooxygenase 1 and 2 enzymes to inhibit the production of prostaglandins. It also inhibits human serum x-ray

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Tiquizium bromide is an experimental drug that has been shown to have a potent anti-inflammatory effect in animal models. The drug was tested as a potential treatment for detrusor muscle dysfunction and found to be effective, with a side effect profile similar to famotidine. Tiquizium bromide inhibits the production of hydrochloric acid by inhibiting acetylcholine release from parasympathetic nerves and may also inhibit the inflammatory response by preventing leukocyte migration. Tiquizium bromide has not been studied in humans, but it is thought that this drug could be used as an alternative therapy for inflammatory diseases such as asthma or colitis.

Stability Moisture Sensitive Applications PERFLUOROHEXANE SULPHONYL FLUORIDE (cas# 423-50-7) is a useful research chemical. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

3-Bromothiophenol is a chemical compound with the formula CHBrS. It is an oily liquid that is soluble in organic solvents. 3-Bromothiophenol has been shown to react with histone H3, forming covalent adducts. These adducts are formed through the reaction of the hydroxy group on 3-bromothiophenol and amino groups on histone H3. The x-ray crystal structures of these molecules have been determined, revealing that they adopt a bent conformation. 3-Bromothiophenol has been used as an activated diode in thermally sensitive diodes, such as those found in light emitting diodes (LEDs).

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2-Chloro-5-iodotoluene is an estrogen receptor antagonist that inhibits the activity of estrogen. 2CIT has been shown to be a potent aromatase inhibitor, and can be used for the treatment of endometriosis and breast cancer. 2CIT has been shown to inhibit the production of estrogen by binding to the aromatase enzyme and preventing it from converting testosterone into estrogen in peripheral tissues such as adipose tissue. This drug can also prevent the conversion of androgens into estrogens in target tissues, including breast tissue. As a result, this drug inhibits tumor growth by preventing the formation of new blood vessels needed for tumor growth. 2CIT may also have anti-cancer properties due to its ability to inhibit DNA synthesis in tumor cells.

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Applications 4-Bromobiphenyl is used as a reagent in the synthesis of spirooxindole derivatives for use as AMPK activators. 4-Bromobiphenyl is also used as a reagent in the preparation of indenoindole derivatives as organic electroluminescent device materials. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Madanahalli Ranganath Rao, J., et al.: PCT Int. Appl. WO 2014202580 A1 20141224. Dec 24, 2014; Nagaoka, M., et al.: PCT Int. Appl. WO 2014196556 A1 20141211. Dec 11, 2014