Organic Halides

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Applications Trimethyl (2-N-t-Butoxycarbonylamino)ethylammonium Bromide is a compound useful in organic synthesis.

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2-Amino-4-(3-chlorophenyl)butanoic acid (2E)-4-[(3-Chlorophenyl)amino]-4-oxobut-2-enoic acid is a hydrogen bond donor that has the planar molecular conformation. The amide hydrogen bonds in this molecule are stabilized by the phenyl chains and phenyl ring. 2E)-4-[(3-Chlorophenyl)amino]-4-oxobut-2-enoic acid contains one phenyl substituent on the amide nitrogen atom. This molecule has a dihedral angle of 180 degrees and conformational energies of 16.1 kcal/mol, which are consistent with a high degree of stability.

Ruthenium(III) chloride is a compound of ruthenium and chlorine that is used in the preparation of pharmaceuticals. Ruthenium(III) chloride reacts with potassium dichromate to form stable complexes, as well as being oxidized by picolinic acid or other oxidizing agents to form stable complexes. It has been shown to be an effective catalyst for organic synthesis reactions and biological studies have shown it can inhibit the growth of bacteria such as Mycobacterium tuberculosis by inhibiting the synthesis of proteins necessary for cell division. Ruthenium(III) chloride also forms complexes with amines and nitrogen atoms, which may be due to its ability to bind with these groups.

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Sodium dichlorofluoroacetate is a chemical compound that is used in the preparation of pharmaceuticals. It has been shown to have anticancer activity and is also used to treat tumor diseases. This drug binds to DNA and inhibits the synthesis of proteins, leading to cell death by inhibiting the production of proteins vital for cell division. Sodium dichlorofluoroacetate can be prepared from ethane (from natural gas) and chlorine gas. The reaction proceeds through the intermediates chloroethane, chloral, and ethyl chloride.

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Impurity Amiodarone EP Impurity H / Amiodarone USP Related Compound H Stability Moisture Sensitive, Hygroscopic Applications 2-Chloro-N,N-diethylethylamine Hydrochloride (Amiodarone EP Impurity H) is a related compound of Amiodarone, a non-selective ion channel blocker. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Bonati, M., et al.: J. Pharm. Sci., 73, 829 (1984), Plomp, T.A., Anal. Profiles Drug Subs., 20, 1 (1991), Chow, M., et al.: Ann. Pharmacother., 30, 637 (1996), Singh, B.N., et al.: Clin. Cardiol., 20, 608 (1997)

(R)-(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine is a chemical compound that belongs to the group of c1-4 alkyl, high yield. It has a chemical formula of C12H17ClN2O and an organic base. This compound is hydrolyzed in vivo to levocetirizine, its active form. (R)-(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine is an antihistamine that binds to H1 receptors in the central nervous system, which results in decreased production of histamine and other proinflammatory substances. It also has optical activity, with (+) being the active form.

Chlorpromazine hydrochloride is an amphiphilic drug, derivative of phenothiazine, that blocks post-synaptic dopaminergic receptors (D1-D4) in mesolimbic area (antipsychotic effects). It is an antagonist at histamine (H1), serotonin (5HT1 and 5-HT2) and alpha-1, alpha 2 adrenergic receptors and possess antimuscarinic properties. Chlorpromazine hydrochloride salt is used in the treatment of: agitation and aggression in bipolar disorder and schizophrenia, in behaviour problems and hyperactivity in children, and for the treatment of chronic hiccups. Also, it helps in: tetanus therapy and intermittent porphyria, the treatment of severe migraines, and helps control nausea and vomiting. Chlorpromazine performs clathrin- mediated endocytosis at non-toxic concentrations and it can be used as a potential broad-spectrum inhibitor of viruses.

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