Biochemicals and Reagents

T807 is a positron emission tomography (PET) tracer that can be used to assess the uptake of T807 in the brain. The structural analysis of T807 has been shown to have binding affinity for neuronal death, and clinical use has demonstrated that T807 can enter the central nervous system. A study in Sprague-Dawley rats has shown that T807 is able to induce symptoms similar to those seen in patients with Parkinson's disease, including degeneration of neurons in the occipital cortex. The effective dose for T807 is unknown; however, it is believed to be more efficient than other PET tracers currently available.

Solcitinib is a Jak1 inhibitor that is being evaluated for its potential to treat cancer. The drug inhibits the activity of the Janus kinase 1 (JAK1) enzyme, which is involved in signaling pathways that are important for cell growth and survival. Solcitinib has been shown to inhibit tumor growth in animal models of cancer and has been shown to be well-tolerated in humans with advanced solid tumors who have previously received treatment with other anti-cancer agents. In addition, solcitinib has been shown to reduce inflammation and improve immune function in animal models of inflammatory bowel disease and bowel disease. This drug may also be effective against autoimmune diseases such as alopecia areata or inflammatory bowel disease.

A synthetic peptide for use as a blocking control in assays to test for specificity of LRRC42 antibody, catalog no. 70R-4131

Rabbit polyclonal GLCTK antibody

1,3,4,6-Tetrachloro-3-6-diphenylglycouril

Peptide H-SSHHHHHHSS-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using H-SSHHHHHHSS-OH include the following: Reconstitution of yeast RNA polymerase I transcription in vitro from purified components: TATA-binding protein is not required for basal transcription J Keener, CA Josaitis, JA Dodd, M Nomura - Journal of Biological , 1998 - ASBMBhttps://www.jbc.org/article/S0021-9258(19)88601-5/abstract

AMG-51 is a synthetic, pegylated, recombinant human monoclonal antibody that binds to the CD20 antigen on the surface of B lymphocytes. It is used for the treatment of certain types of cancers and chronic viral hepatitis. AMG-51 does not crossreact with other antigens and has no effect on normal B cells. This drug has been shown to have diagnostic value in detecting mononuclear cells in hypersplenism and dilemmas associated with thrombocytopenia. AMG-51 also has immunosuppressive effects by inhibiting the proliferation of T cells and macrophages, which may be due to its insulin-like growth factor 1 (IGF-1) activity.

Please enquire for more information about CMI977 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Remikiren is an angiotensin receptor blocker that blocks the binding of angiotensin II to its receptors on cells. It is used to treat high blood pressure and congestive heart failure. Remikiren has been shown to have a low potency in vitro, but it is more potent in vivo and has greater efficacy than losartan at doses of 100 mg/kg/day. This drug also has biochemical properties that are similar to those of other inhibitors of the renin-angiotensin system, such as ACE inhibitors and AT1 antagonists. Remikiren significantly reduces the level of angiotensin II in animals with experimental cardiac disease, which may be due to its ability to inhibit cytokine production by macrophages.

MK-571 is a drug that belongs to the class of ATP-binding cassette transporters. MK-571 has been shown to inhibit multidrug efflux pumps, such as P-glycoprotein (P-gp), and to bind DNA. The optimum concentration of this drug is 0.1 μM, which can be achieved by using MK-571 with nonsteroidal anti-inflammatory drugs (NSAIDs). This agent has been shown to have a protective effect on the myocardium following a myocardial infarct and may also have an inhibitory effect on leukotriene synthesis in bowel disease. MK-571 has also been shown to inhibit polymerase chain reactions and may act as an inhibitor of apical secretions in the gastrointestinal tract.

Saikogenin A is a natural compound found in the tuberous roots of Pueraria lobata that has been shown to have a variety of biological activities. Saikogenin A inhibits protein synthesis through a number of mechanisms, including interfering with the production of growth factors, blocking the conversion of epoxyeicosatrienoic acids to prostaglandins, and inhibiting the activity of human liver cancer cells. It also has anti-inflammatory properties and has been shown to inhibit UV absorption as well as erythromycin-induced uvB damage in human skin cells. The triple-quadrupole mass spectrometry analysis reveals that saikogenin A has absorptions at 336, 338, and 340 nm in urine samples. This suggests that saikogenin A may be metabolized by cytochrome P450 enzymes into metabolites with different absorption spectra.

Mouse monoclonal SETDB1 antibody

β-Glucosidase 1A from Pectobacterium carotovorum

Digoxin antibody was raised in mouse using digoxin-BSA as the immunogen.

ARIH2 antibody was raised in Rabbit using Human ARIH2 as the immunogen

This antibody is suitable for detecting p-Tau 217, a promising biomarker for the detection and monitoring of Alzheimer's Disease

OAKB is a peptide that is derived from the Alzheimer's disease-associated amyloid precursor protein. It has been shown to inhibit the formation of amyloid beta (Aβ) oligomers, which are toxic to nerve cells and thought to be one of the causes of Alzheimer's disease. OAKB also binds to antibodies and can be used as a research tool in immunology, cell biology, pharmacology, and life sciences. OAKB has been shown to inhibit ion channels and receptors, making it an interesting candidate for drug development. OAKB hydrochloride is high purity (>99%) with an inhibitor concentration of 2 mM.

Affinity purified Rabbit polyclonal ADP ribosylation factor 3 antibody

Rabbit polyclonal CD80 antibody