Antibiotics

Framycetin sulfate (Neomycin Sulphate B) belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds.

Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci.

Stability Light Sensitive Applications Labelled Rifabutin (R505000). Semisynthetic derivative of Rifamycin S that inhibits nucleic acid synthesis. An antibacterial (tuberculostatic). References O’Brien, R.J., et al.: Infect. Dis., 9, 519 (1987), Anand, R., et al.: Antimicrob. AG. Chemother., 32 (684 (1988), Skinner, M.H., et al.: Antimicrob. Agent Chemother., 33, 1237 (1989),

7-epi-Clindamycin 2-phosphate is a semisynthetic antibiotic derivative, which is sourced from chemical modifications of the natural antibiotic lincomycin. This compound operates by inhibiting bacterial protein synthesis. It achieves this by binding to the 50S subunit of the bacterial ribosome, thereby obstructing the translocation steps in protein elongation. Primarily, 7-epi-Clindamycin 2-phosphate is utilized in research settings focused on the development and refinement of antibiotics. Its antibacterial properties make it a valuable tool for studying resistance mechanisms and assessing the efficacy of novel antimicrobial agents. This compound is particularly relevant in investigating treatments against Gram-positive bacterial infections, including those caused by resistant strains. By understanding the mode of action and potential applications, scientists can advance the development of more effective therapeutic strategies against bacterial infections.

Gatifloxacin is an antibiotic, which is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. Its source lies in its chemical synthesis, designed to inhibit bacterial enzymes necessary for DNA replication. The mode of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, which are critical enzymes for bacterial DNA replication, transcription, and repair. This dual inhibitory mechanism disrupts bacterial cell division and growth, leading to the eventual eradication of susceptible bacterial strains. Gatifloxacin is primarily used in the treatment of a variety of bacterial infections, including respiratory tract infections, urinary tract infections, and conjunctivitis. Given its broad-spectrum activity, it is effective against both Gram-positive and Gram-negative bacteria. This makes it a valuable asset in clinical settings where the exact bacterial pathogen may not be immediately known, allowing for empirical therapy that can be adjusted once pathogen-specific information is available. Due to its powerful antibacterial capabilities, Gatifloxacin is a critical compound in the arsenal against bacterial infections, especially those that may exhibit resistance to other antibiotic classes.

17β-Estradiol sulfate sodium (17β-Estradiol 3-sulfate sodium) is a neuroactive estrogen with vasoprotective properties that inhibits the growth of Neisseria brasiliensis and disrupts aquatic ecosystems.

Arylomycin A5 is a lipohexapeptide antibiotic (antibiotic) effective against Gram-positive bacteria.

Sultamicillin is an orally active double prodrug of Ampicillin/Sulbactan. Sulbactam is a semisynthetic β-Lactamase inhibitor.