Heterocycles with Nitrogen (N)

4-Amino-1-phenylpyrazolo[3,4-D]pyrimidine is an amphipathic molecule with a molecular weight of 283.33 Da. It has been shown to inhibit the growth of bacteria such as Pseudomonas aeruginosa and Staphylococcus aureus. The biological function of 4-Amino-1-phenylpyrazolo[3,4-D]pyrimidine is not fully understood, but it has been shown to be able to bind to sephadex g-100 beads. The compound has also been shown to have an effect on the natural Ca2+ response in rat neurons, which may be due to its ability to induce neuronal death by inhibiting protein synthesis.

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Applications 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole is an intermediate for the synthesis of Pyraclostrobin-d6 (P840402). Isotope labelled Pyraclostrobin is a fungicide for use in seed grass and food crops. References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),

tert-Butyl 4-(3-(1-amino-2-hydroxyethyl)azetidin-1-yl)piperidine-1-carboxylate is a histone deacetylase inhibitor (HDACi). It binds to the active site of the enzyme and prevents it from removing acetyl groups from lysine residues on histones, thereby blocking transcriptional regulation. The drug has been shown to inhibit the growth of some bacteria, such as Mycobacterium tuberculosis and Mycobacterium avium complex, as well as a host of other eukaryotic cells such as yeast. This drug also has antiinflammatory properties that may be due to its ability to inhibit phosphatases.

(5-chloro-2-fluoropyridin-4-yl)boronic acid is a synthetic compound that is used in organic synthesis as a reagent. It has been shown to have potent antitumor activity against many tumor cell lines, including leukemia, breast, prostate and colon cancer cells. This agent is synthesized by the reaction of 2-bromo-6-fluoropyridine with the boronic acid. The patent for this compound was filed in 1997, and preclinical studies are being conducted to test its safety for human use.

Applications 4-(2-Oxopyrrolidin-1-yl)butanoic acid (cas# 6739-80-6) is a useful research chemical.

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4-Bromo-2-fluoropyridine is a heterocyclic amine that belongs to the class of cannabinoid type. It has been shown to be stereoselective, and can be used as a sulfamidate in biomolecular studies. 4-Bromo-2-fluoropyridine is activated by chloride and nucleophilic, which are properties that make it useful for functional groups. The fluorine atom on this molecule also makes it reactive, making it possible to use the substance as an enantiopure catalyst for organic reactions.

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