Amides

Thiophene-3-carbothioamide is a thiol functionalized molecule that can be immobilized on electrodes. It has been used as an electrode material in electrochemical studies of aspirin and its effect on platelet aggregation. Thiophene-3-carbothioamide has been shown to have a diameter of 10 nm and can be used in the production of polymers by electropolymerization. The synthesis of imidazole derivatives is also possible with this molecule, which could lead to the development of new drugs.

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Please enquire for more information about N-Butyloxycarbonyl-3-[4-(imidazol-1-ylmethyl)-3,5-dimethyl-phenyl]-5-isobutylthiophene-2-sulfonamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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2-Benzotriazol-1-yl-acetamide is a nucleophile that reacts with electrophiles such as acids and amines to produce pyridine derivatives. 2-Benzotriazol-1-yl-acetamide is powerful and regioselective, being able to react at the β position of unsaturated ketones. It is also a good nucleophile in the cyclization of β-unsaturated carboxylic acid derivatives. This compound can efficiently annulate with aromatic amines to form pyridine derivatives or ketones with β-unsaturated carbonyl groups.

Please enquire for more information about D-alpha-(6-Methyl-4-hydroxy-nicotinic acidamide)-p-hydroxyphenyl aceticacid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications N-Isobutylsorbamide shows antitubercular activity towards mycobacterium strains. It is a derivative of Sorbic Acid (S676890), a naturally occurring organic compound first isolated from unripe berries and used as a food preservative and as an inhibitor of Clostridium Botulinum bacteria in meat products. References Gupta, O. et al.: Bull. Med. Ethno-Bot. Res., 1, 99 (1980); Van, M.C., et al.: Int. J. Food. Microbiol., 160, 124 (2012); Li, J., et al.: J. Am. Soc. Mass. Spec., 23, 1625 (2012);

Please enquire for more information about N-Methyl-2-(2-thienylcarbonyl)hydrazinecarbothioamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Propiolamide is a sulfoxide-substituted diphenyl compound that inhibits the growth of cancer cells. It is an irreversible inhibitor of the enzyme, protein kinase C, which has been shown to be involved in the regulation of cell proliferation and differentiation. Propiolamide also inhibits the production of estrone sulfate by inhibiting mitochondrial superoxide production. The hydrochloric acid-catalyzed reaction solution can be prepared using anhydrous sodium as a reducing agent and chemical stability can be achieved by using palladium as a catalyst.

Please enquire for more information about N-Methyl-2-(5-oxo-5,6-dihydro-4H-imidazo[1,2-b][1,2,4]triazol-6-yl)acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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1H-Benzo[d]imidazole-2-carboxamide is a hydrogen bond inhibitor that has been shown to inhibit the activity of enzymes that are involved in neurotransmission. It has been shown to have anti-cancer effects in vitro, and also inhibits tumor growth in vivo. 1H-Benzo[d]imidazole-2-carboxamide is able to inhibit the activity of parp-1, a DNA repair enzyme, which may be one mechanism for its ability to suppress tumor growth. This drug also blocks adp-ribose binding at the benzimidazole site on G proteins and inhibits receptor activity. 1H-Benzo[d]imidazole-2-carboxamide can be taken orally and is not metabolized by cytochrome P450 enzymes.

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2-Chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide is a prodrug that is metabolized to nevirapine, its active form. It is an inorganic base and an aromatic hydrocarbon. The optimal reaction temperature for this compound is around 20°C. 2-Chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide has been shown to be catalytic in the presence of acids or bases and can be used as a prodrug to produce nevirapine. This prodrug has been shown to have antiretroviral activity against HIV strains that are resistant to other drugs.

Please enquire for more information about N,N'-[1,4-Phenylenebis(oxyethane-2,1-diyl)]diacetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

L-Threonine methylamide is a low yield analog of the amino acid L-threonine. It is synthesized by the reaction of L-threonine and methyl amine, which produces an amide bond between the two molecules. L-Threonine methylamide can be used to produce primary amines that are useful in the production of cyclopropylamines and other pharmaceuticals. This compound can also be used as a precursor for α-amino acids such as proline, which are required in the synthesis of proteins.

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Applications N-Dimethyl-(furan-3-ylmethyl)carbamothioyl)methanethioamide is an intermediate used in the synthesis of 3-((Furan-2-ylmethyl)imino]-N,N-dimethyl-3H-1,2,4-dithiazol-5-amine Hydrobromide (F864125), which is an insect chemosterilant and an agrochemical.

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