Amides

1-Ethylsulfanyl-N'-[4-(Trifluoromethyl)Phenyl]Methanimidamide is a neurotrophic drug that inhibits the cellular uptake of ATP. It has been shown to have neurotrophic effects in vitro, including increased neurite outgrowth, and is also known to be effective against chronic lymphocytic leukemia cells. This drug binds to soluble guanylate cyclase (sGC) and prevents activation of the enzyme by adenosine triphosphate (ATP). 1-Ethylsulfanyl-N'-[4-(Trifluoromethyl)Phenyl]Methanimidamide has been shown to inhibit the growth of both normal and leukemia cells in culture. The activity of this drug is dependent on its concentration.

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2-Chloro-N-phenylacetamide is a fluorophore that can be used to detect hydrogen bonds in proteins. It has been used as a fluorescent probe for the study of the reaction products formed by quinoline derivatives with staphylococcus. The fluorescence properties of 2-Chloro-N-phenylacetamide have also been studied in cancer cells, as well as in the presence of chloride ions. This compound reacts with amide groups and is also an antibacterial agent.

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Applications N-Phenethylbenzamide was used for the synthesis of deteurerium-labeled amides within microreactors. References Hooper, J., Watts, P.: J. Labelled Compd. Rad., 50, 189 (2007)

N-(4-Butylphenyl)acetamide is a reactant that can be used in the production of other chemicals. It is an intermediate for the synthesis of a wide range of organic compounds, which makes it a useful building block. N-(4-Butylphenyl)acetamide has been shown to have antihistamine and anti-inflammatory properties. It is also known as acetanilide or 4-butylaniline. This chemical has CAS number 3663-20-5 and a molecular weight of 150.06 g/mol.

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Na -Benzoyl-L-phenylalanine amide is a peptide binding agent that has been shown to have affinity constants for arginine, denaturation, and proteinase inhibitors. The affinity chromatography of this compound was performed in the presence of formaldehyde. It has been shown to be a reagent for semicarbazone, buffers, and urokinase. Na -Benzoyl-L-phenylalanine amide is an analog of the natural substrate arginine and can act as a buffer when it is eluted from the affinity column.

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N-Didesmethyl loperamide is a synthetic opioid receptor agonist that has been optimized for binding affinity to the μ opioid receptor. The compound has been shown to bind with high affinity and selectivity to the μ opioid receptor, with no efficacy at other opioid receptors. N-Didesmethyl loperamide is an analog of loperamide, which it is more efficient than in binding and activating the μ opioid receptor.

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M03273 - Boc-Cys(Acm)-OH

N-Dechloroethyl cyclophosphamide is a metabolic inhibitor that is used in the treatment of cancer. It is classified as an alkylating agent and inhibits ribonucleotide reductase, which prevents the production of DNA, RNA, and protein. The chemical ionization technique has been used to measure the concentration of this compound in human liver and urine samples. N-Dechloroethyl cyclophosphamide can be analyzed using chromatography or mass spectrometry methods.

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Diacetamide is an organic compound that belongs to the class of amides. It has been shown to inhibit the synthesis of proton pumps in receptor cells, which leads to the accumulation of hydrogen ions and a decrease in intracellular pH. Diacetamide is also capable of binding to enzymes through steric interactions with amino acid residues on their active sites. These interactions can lead to competitive inhibition or non-competitive inhibition, depending on the enzyme. Diacetamide also binds to group P2 receptors, which are found in wild-type strains of Escherichia coli and other bacteria. It has been shown that diacetamide interacts with these receptors by forming hydrogen bonds with carbonyl oxygens in the hydrophobic pocket protein region.

N-(3-Iodopyridin-2-yl)pivalamide is an efficient, and chemoselective amidine synthesis. It is a biomolecule that can be synthesized by the coupling of imidazopyridine with 2-iodoaniline. The efficiency of this method is due to the nucleophilic character of the substituents on the 3-position of the pyridine ring. This molecule has been shown to have antimicrobial properties against Staphylococcus aureus and Escherichia coli.

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N-(4-Oxocyclohexyl)acetamide is a synthetic compound that belongs to the family of heterobicyclic amines. It is structurally related to the class of cytotoxic drugs and has been shown to have a cytotoxic effect on leukemia cells. N-(4-Oxocyclohexyl)acetamide interacts with urea nitrogen in the body, forming a d2/d3 receptor. This interaction may be responsible for its cytotoxic effects on leukemia cells, which are sensitive to this receptor. The chemical structure of N-(4-Oxocyclohexyl)acetamide consists of a cyclohexane ring with an oxime group attached at position 4 and an acetamide group attached at position 2. The hydroxy group (-OH) is located on the acetamide side chain.

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2,3-Dihydroxybenzamide is a chemical compound that is used as an antimicrobial agent. It has been shown to have significant cytotoxicity against HIV-infected cells in tissue culture. 2,3-Dihydroxybenzamide inhibits the uptake of iron by human pathogens by binding with the iron and preventing its uptake into the cell. The coordination geometry of 2,3-dihydroxybenzamide is octahedral with the nitrogen atoms occupying two axial positions in a square plane. FTIR spectroscopy confirmed that it binds to ferric iron and prevents its oxidation to ferrous iron. Kinetic data shows that 2,3-dihydroxybenzamide has an uptake rate of 0.076 mmol/L/min in tissue culture medium at 37°C and pH 7.4.