Lactones

Oxypeucedanin methanolate is a naturally occurring furanocoumarin, which is a type of organic compound found predominantly in several citrus plants. This compound is derived from the peels and essential oils of these plants, highlighting its botanical source that is rich in phytochemicals. The mode of action of oxypeucedanin methanolate involves its interaction with biological systems at the molecular level. It is known to exhibit phototoxic properties by forming adducts with cellular macromolecules upon activation by ultraviolet light. Additionally, it may interfere with various biological pathways, potentially offering antioxidant, anti-inflammatory, or antimicrobial effects. In scientific research, oxypeucedanin methanolate is investigated for its potential applications in pharmacology and biochemistry. It serves as a subject of studies exploring new therapeutic agents due to its bioactive characteristics. Moreover, it is used in experimental models to study the effects of natural compounds on human health and disease mechanisms. Researchers are particularly interested in its role in drug development and as a tool for understanding plant-derived secondary metabolites and their interactions within biological systems.

7-Methylcoumarin with strong hepatoprotective activity.

Lactone

7-Demethylsuberosin (7-demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai,and has anti-inflammatory activity,and exhibited inhibitory

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Lactone

Phellopterin is a bioactive compound belonging to the class of furanocoumarins. It is extracted from various plants within the Apiaceae family, notably Angelica and Peucedanum species. These plants are found in diverse geographical regions and have been used in traditional medicine for centuries. The mechanism of action of phellopterin involves its ability to interact with multiple biological pathways. It is known to exhibit inhibitory effects on enzymes and has potential antioxidant properties. Additionally, phellopterin has demonstrated modulation of cellular signaling pathways, which may contribute to its therapeutic potential. Phellopterin is primarily investigated for its applications in pharmacology and medicine. Research suggests that it may have beneficial effects in treating inflammatory conditions, enhancing immune response, and exerting antitumor activities. It is also studied for its neuroprotective effects and potential role in managing neurodegenerative diseases. The compound’s ability to interact with various biomolecular targets makes it a subject of interest in the development of new therapeutic agents. As research progresses, the full spectrum of phellopterin's pharmacological effects continues to be unveiled, leading to its consideration in novel drug development and therapeutic strategies.

Neobyakangelicol is a phytochemical compound, which is a natural product derived from various plant species. Its source is predominantly the roots of certain medicinal plants that are known for their array of bioactive constituents. The mode of action of Neobyakangelicol primarily involves interacting with specific biochemical pathways, potentially including modulation of enzyme activity or receptor binding, which could result in diverse pharmacological effects. The uses and applications of Neobyakangelicol are mainly centered around its potential therapeutic benefits. It has been the subject of research studies exploring its effects in various biological systems, often with a focus on its antioxidant, anti-inflammatory, or other modulatory roles within cellular processes. As such, it is a compound of interest in the field of drug discovery and development, particularly in the quest for new treatments for diseases that involve oxidative stress and inflammation. Additionally, its natural origin as a phytochemical adds a layer of interest for those investigating plant-derived compounds with possible health benefits.

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8-Methoxypsoralen is a furocoumarin compound, which is derived from natural plant sources such as the seeds of the Ammi majus plant. Its primary mode of action involves intercalation into DNA strands and the formation of covalent bonds with pyrimidine bases upon exposure to ultraviolet A (UVA) light. This interaction results in the inhibition of DNA synthesis and cell proliferation. The compound finds extensive applications in the field of dermatology, particularly in PUVA (psoralen and UVA) therapy for the treatment of skin disorders such as psoriasis, vitiligo, and mycosis fungoides. By inducing controlled DNA damage and modulating immune responses, 8-Methoxypsoralen helps reduce the overproduction of skin cells and alleviates symptoms. Its efficacy in repigmenting skin and managing inflammatory skin conditions has been well-documented, making it a valuable agent in therapeutic photochemotherapy protocols.

3-Aminocoumarin (3-aminochromen-2-one) is the key intermediate for the metal complexes.

Lactone