Lactones

Oxypeucedanin is a major coumarin aglycone that can be extracted from Ostericum koreanum, coumarin aglycones have demonstrated various pharmacological effects, including anti-proliferation, anti-inflammation, and anti-pain; based on transcriptional alteration and complicated modulation of MAPK signaling, might be underlying mechanisms responsible for the various pharmacological effects of oxypeucedanin.

Oxypeucedanin is a furanocoumarin compound, which is derived from various plant sources, most notably those in the Apiaceae family such as Peucedanum and Angelica species. It functions primarily as a photoreactive agent, capable of interacting with DNA under ultraviolet (UV) light through a process called photoactivation. Upon UV exposure, it forms covalent bonds with DNA, leading to cross-linking that can disrupt cellular functions. The biological activities of Oxypeucedanin make it relevant in a range of scientific research and potential therapeutic applications. It has been reported to exhibit antioxidant, anti-inflammatory, and antimicrobial properties, offering interest for further studies in pharmacology. Moreover, due to its DNA-interacting capabilities, it is a subject of research in photochemotherapy, particularly for skin conditions such as psoriasis and vitiligo. As with many such compounds, careful consideration of its effects and toxicological profile is critical in the exploration of its applications. Oxypeucedanin continues to be a topic of scientific investigation, exploring its multifaceted roles and potential benefits in human health and disease management.

Psoralen crosslinking between human immunodeficiency virus type 1 RNA and primer tRNA3(Lys).

'Alloimperatorin fights HL-60 leukemia by inducing apoptosis, disrupting cell cycle, and halting migration; it also enhances erythrocyte hemolysis.'

Nodakenetin displays the least irritant and least persistent reactions on mouse ears, and exhibits the least cytotoxic capacity against brine shrimp larvae.

Capensin is an alkaloid-based compound, which is a naturally occurring chemical derived from specific plant sources known for producing bioactive molecules. Its mode of action involves interacting with cellular pathways to produce pharmacological effects, making it of particular interest in biochemical and medical research. Capensin's potential uses and applications span diverse therapeutic areas, including studies on its effects as a candidate for anti-inflammatory or neuroprotective agents. Current research is focused on its ability to modulate neurotransmitter systems and its interactions at the cellular level to uncover pathways and targets of therapeutic potential. While the exact mechanisms and clinical relevance are still under investigation, Capensin provides a promising avenue for developing new therapeutic interventions.

4-Hydroxycoumarin is a synthetic organic compound, which is a derivative of coumarin. This compound derives from a benzopyrone structure, specifically known as a precursor in the synthesis of various anticoagulant agents. Its mode of action involves the inhibition of the enzyme vitamin K epoxide reductase. This inhibition subsequently decreases the synthesis of active clotting factors II, VII, IX, and X by preventing the regeneration of reduced vitamin K. 4-Hydroxycoumarin and its derivatives have pivotal applications in the pharmaceutical sector, particularly in the creation of anticoagulant medications such as warfarin and other pharmaceuticals used to prevent and treat thromboembolic disorders. In addition to their clinical applications, these compounds are also involved in biochemical research exploring enzyme inhibition and coagulation pathways. By providing insight into the molecular interactions between 4-Hydroxycoumarin derivatives and their enzymatic targets, researchers can develop more effective anticoagulant therapies with improved safety profiles.

Scopoletin is a naturally occurring coumarin derivative, which is primarily isolated from plants such as those in the Solanaceae and Asteraceae families. It exhibits a diverse range of biological activities due to its multifaceted mode of action, which includes antioxidant, anti-inflammatory, and antimicrobial properties. As a phytochemical, scopoletin can modulate various biochemical pathways, influencing both enzymatic and receptor-mediated processes. Scopoletin is widely studied for its therapeutic potential in reducing oxidative stress and modulating the immune response, making it a subject of interest in the development of treatments for conditions characterized by inflammation and microbial infections. Additionally, its ability to inhibit certain enzymes and interact with neurotransmitter systems suggests potential applications in neurology and metabolic research. As a scientific compound, scopoletin continues to be an important molecule for further research, contributing to a deeper understanding of plant-based bioactive compounds and their effects on human health.

Natural glycoside

Fabiatrin is a natural product isolated and identified from n-butanol extract of Przewalskia tangutica.

1. Nodakenetin ((-)-Prangeferol) has clinical efficacy.

Praeruptorin C: an antioxidant, calcium antagonist, protects neurons, reduces vascular hypertrophy, affects cellular signals.