Antifungals

Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici.

Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.

A fungicide

Faltan (Folpet), a widely used dicarboximide fungicide, induces tumors in the mouse gastrointestinal tract, primarily in the duodenum.

View and buy Ferrostatin-1 from TargetMol.Ferrostatin-1 is a potent ferroptosis inhibitor (EC50: 60 nM).Cited in 49 publications.

Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols.

Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin.

41-Oxo-rapamycin is a synthetic derivative of rapamycin, which is a macrocyclic lactone. It is derived from Streptomyces hygroscopicus, a gram-positive bacterium known for producing various bioactive compounds. The mode of action of 41-Oxo-rapamycin involves binding to the FK506-binding protein (FKBP12), forming a complex that subsequently inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition results in the suppression of T-cell proliferation and modulation of immune responses. The compound is primarily used in research settings to explore its potential applications in immunosuppressive therapies and organ transplantation. It is also a valuable tool for investigating the mTOR signaling pathway in cancer research, as it has implications in controlling cell growth and proliferation. Moreover, its role in metabolic regulation and potential neuroprotective effects are topics of ongoing study, providing insights into therapeutic approaches for various diseases, including neurodegenerative disorders and metabolic syndromes.

Fludazonium chloride (NSC-351149) is an antifungal agent.

Luliconazole (NND 502) is an Azole Antifungal. The mechanism of action of luliconazole is as a Cytochrome P450 2C19 Inhibitor.

Tolnaftate is a thiocarbamate antifungal agent with action on fungal cell membrane disruption and is used for treating fungal infections like athlete's foot, jock itch, and ringworm.

Applications (5E)-5-(3-Bromopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

Clotrimazole is an azole antifungal medication with action on fungal cell membrane disruption and is used for treating fungal infections like athlete's foot, ringworm, and vaginal yeast infections.

Colutehydroquinone is an antifungal isoflavonoid from Colutea arborescens.

Caspofungin Acetate (MK 0991) is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the

Exalamide is an arenecarboxamide antifungal agent with action on fungal growth inhibition and is used for research on fungal infections.

2-Butyl-1,2-benzisothiazolin-3-one is an orally available antimicrobial agent with antimicrobial activity commonly used in the pharmaceutical profession and

2,4,6-Tribromophenyl caproate is a potent antifungal agent.