Antivirals
Antivirals are compounds specifically designed to inhibit the replication and spread of viruses, playing a critical role in the treatment and prevention of viral infections. In this category, you will find a comprehensive selection of antiviral agents intended for laboratory research purposes only. These products are essential for studying viral mechanisms, developing new antiviral therapies, and understanding resistance patterns. Researchers can utilize these antivirals to investigate the efficacy and safety of potential treatments, contributing to the advancement of medical science and the development of innovative antiviral drugs. The availability of diverse antiviral agents supports cutting-edge research in virology and enhances our ability to combat viral diseases.
Products of "Antivirals"
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HIV-1 Nef-IN-1
CAS:HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).Formula:C18H16O2Purity:99.90%Color and Shape:SolidMolecular weight:264.324-Nitrophenyl Thiazol-5-ylmethyl Carbonate
CAS:Controlled ProductFormula:C11H8N2O5SColor and Shape:NeatMolecular weight:280.26L-Chicoric Acid
CAS:L-Chicoric Acid (trans-Caffeoyltartaric acid) has been shown to inhibit hyaluronidase and HIV-1 integrase, and to possess phagoeytosis stimulatory activity.Formula:C22H18O12Purity:98.33% - 99%Color and Shape:SolidMolecular weight:474.37Ref: TM-T6S2391
2mg44.00€5mg65.00€10mg93.00€25mg155.00€50mg220.00€100mg328.00€200mg487.00€1mL*10mM (DMSO)67.00€Dolutegravir
CAS:Dolutegravir is an HIV-1 integrase inhibitor. Dolutegravir is used in the treatment of HIV-1 infections as it hampers the integration of the viral genome into the host DNA (Katlama, 2012). Active on a wide number of HIV-1 phenotypes, dolutegravir is highly bioavailable with an IC90 of more than 30 hours (Cottrell, 2013).Formula:C20H19F2N3O5Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:419.40 g/molNaphthalene-2-thiol
CAS:Formula:C10H8SPurity:80%Color and Shape:SolidMolecular weight:160.23551999999998Faldaprevir
CAS:Hepatitis C virus protease inhibitorFormula:C40H49BrN6O9SPurity:Min. 95%Color and Shape:White PowderMolecular weight:869.82 g/mol5S-2-Amino-5-dibenzylamino-4-oxo-1,6-diphenylhex-2-ene
CAS:Controlled ProductApplications An intermediate in the synthesis of Ritonavir. References Sham, H., et al.: Bioorg. Med. Chem. Lett., 12, 3101 (2002),Formula:C32H32N2OColor and Shape:NeatMolecular weight:460.61Ganciclovir 100 µg/mL in Acetonitrile:Water
CAS:Formula:C9H13N5O4Color and Shape:Single SolutionMolecular weight:255.23Abacavir sulfate
CAS:Formula:C14H18N6O·5(H2SO4)Purity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:335.37Abacavir Triphosphate TEA Salt
CAS:Controlled ProductFormula:C14H21N6O10P3·xCH15NColor and Shape:NeatMolecular weight:526.27 + (101.19)x4-Morpholinecarboximidamide, N-(aminoiminomethyl)-,monohydrochloride
CAS:Formula:C6H14ClN5OPurity:98%Color and Shape:SolidMolecular weight:207.66126000000006Oseltamivir-d3 Phosphate
CAS:Controlled ProductStability: Hygroscopic Applications: Labelled Oseltamivir (O701000). Orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug. It is a COVID19-related research product. References Oliyai, R., et al.: Pharm. Res., 15, 1300 (1998), Kim, C.U., et al.: Med. Chem. Res., 8, 392 (1998), Hayden, F.G., et al.: N. Engl. J. Med., 341, 1336 (1999), Treanor, J.J., et al.: J. Am. Med. Assoc., 283, 1016 (2000)Formula:C16H28D3N2O8PColor and Shape:NeatMolecular weight:413.42Raltegravir potassium salt
CAS:Formula:C20H20FKN6O5Purity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:482.512-Hydroxy-N-phenylbenzamide
CAS:Formula:C13H11NO2Purity:95%Color and Shape:SolidMolecular weight:213.2319(2R,3S)-N-Benzoyl-3-phenyl Isoserine Ethyl Ester
CAS:Applications (2R,3S)-N-Benzoyl-3-phenylisoserine ethyl ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites. (2R,3S)-N-Benzoyl-3-phenylisoserine ethyl ester shows cytotoxic, antiviral and immunomodulatory activity. References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);Formula:C18H19NO4Color and Shape:White To Off-WhiteMolecular weight:313.35Dodecyl gallate
CAS:Dodecyl gallate (Progallin LA) is the ester of gallic acid and dodecanol. As a food additive, it is used as a preservative and antioxidant.Formula:C19H30O5Purity:99.74%Color and Shape:White Or Creamy-White Odourless SolidMolecular weight:338.44Sofosbuvir
CAS:Potent inhibitor of viral RNA polymerase called non-structural protein 5B (NS5B). This nucleotide analog is effective against Hepatitis C virus (HCV) infection since it inhibits viral RNA replication. Sofosbuvir is a prodrug and gets triphosphorylated in the liver cells, generating biologically active compound with anti-viral activity.Formula:C22H29FN3O9PPurity:Min. 95%Color and Shape:Off-White PowderMolecular weight:529.45 g/molNevirapine
CAS:Formula:C15H14N4OPurity:98.0 - 102.0 % (dried basis)Color and Shape:White to off-white crystalline powderMolecular weight:266.308-Hydroxy Efavirenz (~90%)
CAS:Controlled ProductApplications 8-Hydroxy Efavirenz is a metabolite of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. References Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994), Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1998), Langmann, P., et al.: Eur. J. Med. Res., 7, 309(2002), Chang, T., et al.: Drug Metab. Dispos., 31, 7 (2003),Formula:C14H9ClF3NO3Purity:~90%Color and Shape:NeatMolecular weight:331.67(4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
CAS:Formula:C14H9ClF3NO2Purity:98%Color and Shape:SolidMolecular weight:315.675Indinavir sulphate hydrate
CAS:Formula:C36H47N5O4·H2SO4·xH2OPurity:≥ 98%Color and Shape:White powderMolecular weight:711.87Boceprevir-d9
CAS:Controlled ProductApplications A labelled NS3 serine protease inhibitor of hepatitis C virus. It is a COVID19-related research product. References Malcolm, B., et al.: Antimicrob. Agents Chemother., 50, 1013 (2006); Cubero, M., et al.: Virology, 370, 237 (2008); Venkatraman, S., et al.: J. Med. Chem., 49, 6074 (2006);Formula:C272H9H36N5O5Color and Shape:NeatMolecular weight:528.73Diisopropyl [[(2R)-1-(6-Amino-9H-purin-9-yl)propan-2-yloxy]methyl]phosphonate
CAS:Formula:C15H26N5O4PAnthraquinone-D8
CAS:Controlled ProductApplications Anthraquinone-D8 is a labelled analogue of Anthraquinone (A679245). Anthraquinone is commonly used as a precursor to synthesize antiviral compounds such as Hypericin (H998190). Anthraquinone and its derivatives are also used in textile dyes. References Andersen, D., et al.: Antivir. Res., 16, 185 (1991); Lee, Y. & Pavlostathis, S.: Water Res., 38,1838 (2004); Walker, G. & Weatherley, L.: Env. Poll., 108, 219 (2000)Formula:C142H8O2Color and Shape:Light YellowMolecular weight:216.262-Propanone, 1-[2-(trifluoromethyl)phenyl]-
CAS:Formula:C10H9F3OPurity:98%Color and Shape:LiquidMolecular weight:202.17313-Methoxyflavone
CAS:3-Methoxyflavone is a Flavonoids, with antiviral activityFormula:C16H12O3Purity:99.29% - 99.97%Color and Shape:SolidMolecular weight:252.264-epi-Ritonavir
CAS:Controlled ProductImpurity Ritonavir EP Impurity O Applications 4-epi-Ritonavir (Ritonavir EP Impurity O) is an isomer of Ritonavir (R535000), a selective HIV protease inhibitor. It is a COVID19-related research product. References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788(2006)Formula:C37H48N6O5S2Color and Shape:NeatMolecular weight:720.94Telaprevir
CAS:Formula:C36H53N7O6Purity:≥ 99.0%Color and Shape:White to light yellow powderMolecular weight:679.85
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