Antivirals

Potent antiviral against HCMV and Epstein-Barr virus (EBV)

Applications 1-[2-Deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-D-erythro-pentofuranosyl]-1H-1,2,4-triazole-3-carboxamide is an intermediate in the synthesis of 2’-Deoxyribavirin-5’-triphosphate (D2149940) Triethylamine Salt, a potential new inhibitor for HIV-1 replication. References Vivet-Boudou, V., et al.: Nucleos. Nucleot. Nucl., 26, 743 (2007);

SHEN26 has antiviral activity and can be used in research on the treatment of viral infections.

Acetyl daclatasvir is a direct-acting antiviral agent, which is chemically derived from a series of small-molecule inhibitors. The source of this compound lies in rational drug design, focusing on targeting specific viral proteins involved in the replication of hepatitis C virus (HCV). Its mode of action involves inhibiting the NS5A protein, a non-structural protein essential for HCV RNA replication and virion assembly. By binding to NS5A, acetyl daclatasvir disrupts the replication complex, effectively halting the virus's ability to multiply within the host cells. The primary uses and applications of acetyl daclatasvir are centered around its role in hepatitis C research, where it is utilized to study viral life cycles and evaluate antiviral efficacy in laboratory settings. Given its specificity and potency, acetyl daclatasvir serves as a critical tool in the development of therapeutic strategies and understanding HCV biology.

Applications Stavudine-alpha,alpha,alpha,6-d4 (CAS# 1219803-67-4) is a useful isotopically labeled research compound.

Applications 2-Acetoxy-N-(2-thiazolyl)-benzamide is used in the synthesis of thiazolides as novel antiviral agents. Used in the inhibition of hepatitis C virus replication. Nitazoxanide Impurity References Edwards, G. et al.: J. Med. Chem., 54, 8670 (2011);

Famciclovir is a guanosine analogue antiviral agent that is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. It works by inhibiting the replication of the herpes virus. Famciclovir prevents viral DNA synthesis by inhibiting the viral DNA polymerase and by blocking viral DNA replication. Its active form is penciclovir. Famciclovir is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

GFP16 is a compound with potential prion antiviral activity, used in prion research.