Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Products of "Antiparasitics"
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GNF179
CAS:GNF179 is an optimized 8,8-dimethyl IP analog.Formula:C22H23ClFN5OPurity:98.9%Color and Shape:SolidMolecular weight:427.9Ref: TM-T15409
1mg133.00€5mg274.00€10mg454.00€25mg750.00€50mg1,026.00€100mg1,406.00€1mL*10mM (DMSO)303.00€MMV390048
CAS:MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM).Formula:C18H14F3N3O2SPurity:97.48%Color and Shape:SolidMolecular weight:393.38Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Formula:C14H10F3NO2Purity:98.68%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:281.23GUANABENZ
CAS:GUANABENZ is a Central alpha-2 Adrenergic Agonist. The mechanism of action of guanabenz is as an Adrenergic alpha2-Agonist.Formula:C8H8Cl2N4Purity:98.31%Color and Shape:White Solid From Acetonitrile SolidMolecular weight:231.08Ref: TM-T5471
2mg35.00€5mg48.00€10mg65.00€25mg104.00€50mg148.00€100mg215.00€200mg319.00€1mL*10mM (DMSO)50.00€Artesunate
CAS:Formula:C19H28O8Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:384.435-Amino-1-(1,1-dimethylethyl)-3-[(3-methylphenyl)methyl]-1H-pyrazole-4-carbonitrile
Controlled ProductApplications 5-Amino-1-(1,1-dimethylethyl)-3-[(3-methylphenyl)methyl]-1H-pyrazole-4-carbonitrile is an derivative in the synthesis of small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by toxoplasma gondii. References Lourido, S., et al.: J. Med. Chem., 56, 3068 (2013);Formula:C17H22N4Color and Shape:NeatMolecular weight:282.383Anticancer agent 140
Compound 140 (Compd 3) exhibits potential anticancer and antiparasitic activities [1].Formula:C20H26N2OPurity:98%Color and Shape:SolidMolecular weight:310.43(6R,13S,25R)-5-O-Demethyl-28-deoxy-5-O-[(1,1-dimethylethyl)dimethylsilyl]-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl] Milbemycin B
CAS:Controlled ProductApplications (6R,13S,25R)-5-O-Demethyl-28-deoxy-5-O-[(1,1-dimethylethyl)dimethylsilyl]-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl] Milbemycin B is an intermediate used in the synthesis of Milbemycin D (M344290), which is a macrocyclic lactones that can be used as a nematocide and insecticide. References Arena, J. P., et al.: J. Parasitol 81, 286 (1995); Takiguchi, Y., et al.: J. Antibiot 36, 502 (1983)Formula:C40H64O8SiColor and Shape:NeatMolecular weight:701.02Niclosamide olamine
CAS:Niclosamide olamine (Niclosamide Ethanolamine salt) is an Repellent, Insect Attractant and Chemosterilant.Formula:C15H15Cl2N3O5Purity:99.89%Color and Shape:Bright Yellow Crystalline Physical Description Yellow Solid Insoluble In Water (Ntp 1992)Molecular weight:388.2Bephenium (hydroxynaphthoate)
CAS:Bephenium hydroxynaphthoate is a B-type AChR activator, formerly used in the treatment of hookworm infections and ascariasis.Formula:C28H29NO4Purity:99.87%Color and Shape:SolidMolecular weight:443.53Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Chloroquine-d4 Phosphate Salt
CAS:Controlled ProductApplications Labelled anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. It is a COVID19-related research product. References Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),Formula:C18H22D4ClN3•xH3PO4Color and Shape:Yellow SolidMolecular weight:323.9098AZ960
CAS:AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formula:C18H16F2N6Purity:96.02% - 98.51%Color and Shape:SolidMolecular weight:354.36Dichlorophen
CAS:Dichlorophen (DDM) is a nontoxic laxative vermicide of chlorinated phenol compound.Formula:C13H10Cl2O2Purity:99.11%Color and Shape:Colorless Crystals Slight Phenolic Odor And A Saline Phenolic Taste Moderately Toxic Used As A Fungicide AndMolecular weight:269.12Antimalarial agent 27
Antimalarial agent 27 (compound 11a) potently inhibits P.Formula:C10H11NNaO5PPurity:98%Color and Shape:SolidMolecular weight:279.16Antiparasitic agent-18
CAS:Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T.Formula:C25H21N7OPurity:98%Color and Shape:SolidMolecular weight:435.48Flubendazole
CAS:Formula:C16H12FN3O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:313.29Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purity:99.54% - 99.92%Color and Shape:SolidMolecular weight:897.1Ref: TM-T2P2806
1mg48.00€5mg120.00€10mg170.00€25mg283.00€50mg430.00€100mg620.00€1mL*10mM (DMSO)170.00€2-Acetamido-5-nitrothiazole
CAS:Formula:C5H5N3O3SPurity:>98.0%(T)(HPLC)Color and Shape:White to Amber powder to crystalMolecular weight:187.17N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
CAS:Controlled ProductApplications N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine is a metabolite of Chloroquine (C379965), a standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ. References Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),Formula:C18H26ClN3Color and Shape:Dark Orange To Dark BrownMolecular weight:319.87
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