Flavonoids

7-O-Prenyloxyflavanone is a bioactive compound, specifically a flavanone, which is isolated from various plant sources known for their rich flavonoid content. The compound is characterized by the attachment of a prenyl group at the 7-O position of the flavanone structure, which imparts unique biological activities. This prenylated flavonoid exhibits its mode of action primarily through the modulation of key cellular pathways. It has been shown to inhibit the proliferation of cancer cells by inducing apoptosis and arresting the cell cycle. Additionally, 7-O-Prenyloxyflavanone can modulate oxidative stress and inflammatory responses, contributing to its potential therapeutic effects. The uses and applications of 7-O-Prenyloxyflavanone are predominantly found in the field of cancer research. Studies have investigated its efficacy in various cancer models, including those of breast and prostate cancer. Its role as a potential lead compound in drug development highlights its importance in chemopreventive and therapeutic strategies. Furthermore, its natural origin and specific bioactivity make it a valuable subject in the exploration of plant-derived compounds with medicinal potential.

Scutellarein analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Impurity Diosmin EP Impurity B Applications Hesperidine (Diosmin EP Impurity B) is a flavanone found in citrus fruits, also regarded as Vitamin P. References Ananth, V., et al.: J. Pharm. Res., 2, 1739 (2009), Cejudo B., et al.: J. Agric. Food Chem., 58, 11814 (2010),

Sakuranetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

(+/-)-Hesperetin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Rotenone is a naturally occurring insecticide and piscicide, which is derived from the roots of several tropical and subtropical plant species, primarily from the Leguminosae family. Its primary source includes plants such as *Derris* and *Lonchocarpus*. Rotenone works by inhibiting cellular respiration. Specifically, it interferes with the mitochondrial electron transport chain by binding to complex I, blocking the production of ATP and ultimately leading to cell death. This compound is extensively used in agricultural settings to control insect pests on crops due to its botanical origins and perceived lower persistence in the environment compared to synthetic alternatives. In addition, rotenone is employed as a piscicide to manage fish populations in bodies of water, aiding in the removal of invasive or undesirable species. Despite its widespread use, it should be applied with caution due to its high toxicity to non-target aquatic organisms and potential environmental impact. Rigorous understanding of its biochemical interactions and field dynamics is essential for scientists engaged in formulating effective pest control protocols while mitigating ecological risks.

4'-Hydroxy-7-methoxyisoflavan is a naturally occurring isoflavan, which is a subclass of flavonoids typically found in legumes and various plant sources. This compound is derived from the phenylpropanoid pathway, a critical biosynthetic route in plants responsible for producing a variety of phenolic compounds. Its mode of action is largely attributed to its ability to interact with cellular signaling pathways, exhibiting antioxidant, anti-inflammatory, and potentially estrogenic activities. These properties allow 4'-Hydroxy-7-methoxyisoflavan to modulate oxidative stress by scavenging free radicals and influencing gene expression related to detoxification enzymes. The compound is studied extensively for its diverse biological activities and applications in medicinal research. It is of particular interest in the fields of cancer research, cardiovascular health, and neuroprotection due to its involvement in cell signaling mechanisms. Furthermore, its potential estrogenic effects make it a candidate for research in the treatment of menopausal symptoms. Ongoing studies aim to elucidate its mechanistic roles and therapeutic viability in various biological systems.

Syringetin is a flavonoid compound, which is derived from natural sources such as grapes and other plants. This compound belongs to the class of polyphenolic compounds known as flavonols, which are secondary metabolites found abundantly in nature. Syringetin exhibits its mode of action primarily through its strong antioxidant properties, which allow it to neutralize free radicals and reduce oxidative stress in biological systems. This activity can contribute to the protection of cells and biomolecules from oxidative damage, a process implicated in aging and various diseases. The uses and applications of syringetin are diverse, particularly in research on its potential health benefits. It is studied for its role in cardiovascular health, neuroprotection, and anti-inflammatory effects, making it a compound of interest in the fields of nutrition and pharmacology. Additionally, syringetin is explored for its potential as a therapeutic agent due to its ability to modulate signaling pathways related to oxidative stress and inflammation, suggesting its possible applications in the development of dietary supplements and pharmaceuticals.

Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.

Maackiaflavanone is a specialized flavanone, which is a type of natural compound. It is derived from the Maackia plant species, particularly found in temperate regions and known for its rich phytochemical profile. The flavanone exhibits its activity primarily through its interaction with cellular pathways associated with oxidative stress and inflammation, modulating various biochemical signals that can influence cell behavior. Maackiaflavanone is studied for its potential therapeutic applications due to its antioxidant and anti-inflammatory properties. Current research focuses on its effects in the management of chronic conditions such as cardiovascular diseases, cancers, and neurodegenerative disorders. The flavanone acts by scavenging free radicals and modulating the expression of genes related to inflammatory pathways, offering a promising natural alternative in the development of new therapeutic agents. Further studies are ongoing to elucidate its full potential and mechanisms of action.

Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.

(±)-Eriodictyol is a flavonoid compound, which is a type of bioactive polyphenol. It is derived primarily from certain plant sources, notably within the Ericaceae and Solanaceae families. The compound exhibits its mode of action through its potent antioxidant and anti-inflammatory activities, mechanisms that involve the scavenging of free radicals and the inhibition of pro-inflammatory pathways. These biochemical interactions contribute to its potential therapeutic applications, and (±)-Eriodictyol has been studied for its roles in modulating cellular oxidative stress and inflammatory responses. Because of these properties, it is being explored in various fields such as pharmacology and nutraceuticals for its potential benefits in managing conditions related to oxidative stress and inflammation, including cardiovascular and neurodegenerative diseases. Moreover, its potential use in developing natural preservatives in food and cosmetic industries is also under investigation.

Isowighteone is a naturally occurring flavonoid, which is derived from various plant sources, particularly in traditional medicinal herbs. Its biological activity stems from its structure, characterized by phenolic hydroxyl groups that enable it to participate in redox reactions, highlighting its antioxidant properties. Isowighteone's mode of action involves scavenging free radicals and modulating signaling pathways related to oxidative stress, which may contribute to its potential therapeutic effects. Through these mechanisms, it is capable of influencing cellular processes, rendering it a molecule of interest in biochemistry and pharmacology. In scientific research, Isowighteone is explored for its applications in developing treatments for oxidative stress-related conditions, including chronic inflammation, cardiovascular diseases, and certain neurodegenerative disorders. Understanding its interactions at the molecular level can lead to advancements in therapeutic strategies that capitalize on its antioxidative capabilities. Scientists are particularly interested in its potential role in modulating enzyme activities and influencing gene expression linked to cellular defense mechanisms.