Flavonoids

Eupatilin is a flavonoid compound, which is derived from the Artemisia species. This plant-based source has been traditionally used in various medicinal applications across different cultures. Eupatilin’s mode of action involves inhibition of pro-inflammatory cytokines and modulation of signaling pathways associated with inflammation, such as the NF-kB pathway. Additionally, it has been found to possess antioxidant activities, which further contributes to its therapeutic potential. Eupatilin is primarily utilized in scientific research focusing on its anti-inflammatory and antioxidant properties. Its applications extend to studies on chronic inflammatory conditions, including gastrointestinal disorders, where it exhibits protective effects on gastric mucosa. Understanding the precise mechanisms of action and potential therapeutic benefits of Eupatilin can contribute to the development of novel anti-inflammatory agents and offer promising avenues for research into plant-derived compounds.

Hesperetin 7-O-glucoside is a flavonoid derivative, which is commonly found in citrus fruits, particularly in their peels. This compound belongs to the class of flavonoids known as glycosylated flavonoids, which are characterized by the attachment of a glucose molecule to the flavonoid aglycone. Hesperetin 7-O-glucoside is sourced primarily from citrus fruits such as oranges, lemons, and grapefruits. It is usually extracted during the processing of these fruits or their juices. The compound is a derivative of hesperetin, a prominent flavonoid found in high concentrations in citrus species. In terms of its mode of action, Hesperetin 7-O-glucoside exhibits a range of bioactivities. It functions as an antioxidant, scavenging free radicals and reducing oxidative stress in biological systems. Additionally, it has been shown to have anti-inflammatory properties by modulating the activity of enzymes and cytokines involved in inflammation. Hesperetin 7-O-glucoside is used in various applications, especially in research focused on its potential health benefits. It is studied for its possible roles in cardiovascular health, metabolic regulation, and its protective effects against certain diseases. Its applications extend to pharmacological research and the development of nutraceuticals and functional foods aimed at promoting health and wellness.

Quercetagetin-7-O-glucoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Oxygen-heterocyclic compound

(S)-Naringenin is a naturally occurring flavonoid compound, which is found predominantly in citrus fruits, such as grapefruits and oranges. Its source lies within the plant secondary metabolites known for their diverse biological activities. As a flavanone, (S)-naringenin acts primarily as an antioxidant, effectively scavenging reactive oxygen species and thereby protecting cells from oxidative stress. Additionally, it exhibits anti-inflammatory actions by modulating various signaling pathways and inhibiting the production of pro-inflammatory cytokines. (S)-Naringenin is utilized extensively in scientific research due to its broad spectrum of biological activity. It is of particular interest in studies related to chronic diseases, including cardiovascular disorders and certain cancers, owing to its potential to regulate lipid metabolism and influence cell cycle progression. Furthermore, it has been explored for its neuroprotective and hepatoprotective effects, positioning it as a promising candidate in therapeutic investigations. Increasing understanding of its mechanisms continues to guide research into its possible applications in clinical settings.

Natural glycoside

Natural glycoside

2'-Benzyloxy-7,4'-dimethoxyisoflavone is a synthetic isoflavone, which is primarily derived from the benzyl ether of naturally occurring flavones. Isoflavones are typically sourced from plants, such as soybeans, and are known for their estrogenic activity and various biological effects. The modification to produce 2'-Benzyloxy-7,4'-dimethoxyisoflavone involves chemical synthesis that retains the core isoflavone structure while introducing specific substituents to enhance its biological properties. The mode of action of 2'-Benzyloxy-7,4'-dimethoxyisoflavone involves modulation of cellular pathways associated with inflammation and oxidative stress. It is hypothesized to interact with estrogen receptors, similar to other isoflavones, influencing gene expression patterns that regulate these physiological processes. This interaction potentially leads to anti-inflammatory and antioxidant effects. The uses and applications of 2'-Benzyloxy-7,4'-dimethoxyisoflavone are primarily in the area of biomedical research, where it serves as a tool for exploring the therapeutic potentials of modified isoflavones. Researchers investigate its potential in models of inflammation-related diseases and its efficacy as a novel compound with enhanced bioactivity compared to naturally occurring isoflavones. The compound may also be explored for its role in preventing oxidative damage in cellular systems.

7-Hydroxyflavone-beta-D-glucoside is a glucoside compound, which is a type of natural flavonoid derivative. This compound is derived from plant sources, particularly those rich in flavonoids, where it is a metabolite formed through the glycosylation of 7-hydroxyflavone. The mode of action of 7-Hydroxyflavone-beta-D-glucoside involves interacting with cellular antioxidative pathways. It potentially offers protection against oxidative stress by scavenging free radicals and modulating enzyme activities related to oxidative metabolism. Primarily investigated for its bioactive properties, 7-Hydroxyflavone-beta-D-glucoside shows promise in the areas of pharmacology and nutraceuticals. Its antioxidative potential makes it a candidate for contributing to the reduction of cellular damage processes and could be explored for therapeutic benefits in degenerative diseases or conditions exacerbated by oxidative stress. Researchers are particularly interested in its implications for neuroprotection and anti-inflammatory applications. Although its full potential is yet to be realized, ongoing studies continue to explore its efficacy and mechanisms in various biological contexts.

3'-Methoxy-β-naphthoflavone is a synthetic compound, classified as a flavonoid derivative, which is widely utilized in scientific research as a potent inducer and modulator of cytochrome P450 enzymes, particularly CYP1A1 and CYP1A2. Its source is entirely chemical synthesis, allowing for controlled study of its physiological effects without interference from naturally occurring impurities. The primary mode of action of 3'-Methoxy-β-naphthoflavone involves binding to the aryl hydrocarbon receptor (AhR), leading to upregulation of phase I metabolic enzymes. This process is critical in understanding the metabolism of various xenobiotics and the bioactivation of procarcinogens. In applications, 3'-Methoxy-β-naphthoflavone is extensively employed in toxicological studies to assess the role of cytochrome P450 enzymes in drug metabolism and chemical carcinogenesis. It serves as a research tool in pharmacology and biochemistry for dissecting the complex interactions between environmental chemicals and biological systems. By elucidating enzyme induction pathways, it aids in the development of therapeutic strategies for addressing adverse drug reactions and exposure to environmental pollutants.

4'-Methoxyflavonol is a flavonoid compound, which is a naturally occurring secondary metabolite primarily found in various plant species. It is characterized by the presence of a methoxy group attached to the flavonol backbone, contributing to its unique chemical properties. Through its antioxidant activity, 4'-Methoxyflavonol plays a crucial role in neutralizing free radicals and reducing oxidative stress within cells. This compound is predominantly sourced from plants, where it serves to protect against environmental stressors, including pathogens and UV radiation. Its mode of action involves scavenging reactive oxygen species and modulating cellular signaling pathways linked to inflammation and apoptosis. This antioxidative activity not only helps maintain cellular integrity but also supports various physiological processes. In scientific applications, 4'-Methoxyflavonol is explored for its potential therapeutic benefits, particularly in the fields of pharmacology and nutraceuticals. Researchers investigate its effects on chronic diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions. Furthermore, its role in enhancing plant resilience makes it a subject of interest in agricultural studies, aiming to improve crop resistance to stressors. The continued exploration of this flavonoid's bioactivities may contribute to innovative approaches in health and agriculture.

Apigenin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK).

Didymin is a flavonoid compound, which is a type of polyphenolic molecule. It occurs naturally in certain citrus fruits and plants, representing a secondary metabolite with bioactive properties. Didymin exhibits antioxidative activity by neutralizing free radicals and reducing oxidative stress, primarily through the modulation of cellular signaling pathways. This mechanism involves the enhancement of endogenous antioxidant defenses and the inhibition of pro-inflammatory mediators. The compound is of significant interest in scientific research due to its potential therapeutic applications. It is investigated for its role in preventing chronic diseases, including cardiovascular disorders and cancer. Didymin's anti-inflammatory and chemopreventive properties make it a subject of study in the context of metabolic and age-related diseases. Furthermore, its ability to modulate cellular pathways suggests possibilities for applications in neuroprotection and improving overall cellular health. Ongoing research aims to elucidate its efficacy and safety in clinical settings, as well as its potential synergistic effects with other bioactive compounds.