Flavonoids

Kaempferol-7-O-glucoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Natural glycoside

Quercetagetin is a flavonoid compound, which is naturally sourced from the marigold plant, *Tagetes* species. This flavonoid is structurally related to other polyphenols and is synthesized in plants through the phenylpropanoid pathway. Quercetagetin primarily exerts its biological effects through the scavenging of reactive oxygen species (ROS) and modulating various signaling pathways associated with oxidative stress. The compound has garnered significant attention in research due to its potential applications in health-related fields. Its antioxidant properties allow it to mitigate oxidative damage in cells, which is a process implicated in aging and various chronic diseases. Additionally, quercetagetin is being explored for its role in modulating inflammatory responses, thereby contributing to its potential therapeutic effects in inflammatory disorders. In the laboratory setting, quercetagetin is utilized to study its interactions with biomolecules and its effects on cellular pathways. Its role in biochemistry and pharmacology is thus being extensively investigated, with a focus on elucidating its potential benefits and mechanisms of action in biological systems.

Applications O-Methylated metabolite of the flavanoid Quercertin (Q509500) with antioxidant activity. References Soobrattee, M.A. et al.: Mut. Res. Fund. Mol. Mech. Mutagen., 579, 200 (2005); Yamamoto, N. et al.: Arch. Biochem. Biophys., 372, 347 (1999);

2',7-Dihydroxy-5,8-dimethoxyflavanone is a natural flavanone, which is a type of polyphenolic compound. It is derived from various plant sources where flavonoids are commonly found, such as fruits, vegetables, and certain herbs. This particular flavanone exhibits a unique chemical structure characterized by dihydroxy and dimethoxy functional groups, which contribute to its biological activity. The mode of action of 2',7-Dihydroxy-5,8-dimethoxyflavanone primarily involves its antioxidant properties. It acts by scavenging free radicals and reducing oxidative stress within biological systems. This capacity to neutralize reactive oxygen species underlies its potential therapeutic effects, including anti-inflammatory and anti-cancer activities. In scientific research, 2',7-Dihydroxy-5,8-dimethoxyflavanone is utilized primarily to explore its role in disease prevention and health promotion. Studies investigate its efficacy in modulating cellular pathways involved in oxidative stress and inflammation, highlighting its promise in the development of novel therapeutic agents. Researchers are also interested in its potential application in nutraceuticals and pharmaceuticals, where it may contribute to formulations designed to support cellular health and protect against oxidative damage.

Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells; it inhibits the accumulation of the intracellular lipids by decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase.

Hispidulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

6-Hydroxyflavone analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Flavone (2-Phenyl-4-chromone) have effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body.

3-Methoxyflavone is a Flavonoids, with antiviral activity

Acacetin 7-O-methyl ether is a flavonoid derivative, which is a secondary metabolite primarily derived from various plants, including those in the Asteraceae family. This compound is biosynthesized as part of the plant's natural defense mechanism against herbivores and pathogens. Acacetin 7-O-methyl ether exhibits its biological activities through various modes of action, including anti-inflammatory and antioxidant effects, by inhibiting key signaling pathways and modulating enzyme activities. In the scientific community, this compound is of interest due to its potential therapeutic applications, particularly in the fields of pharmacology and medicine. It has been studied for its role in modulating inflammatory responses, which can be crucial for developing treatments for chronic inflammatory diseases. Additionally, its antioxidant properties are explored for protecting cellular structures from oxidative stress, a contributing factor in aging and various degenerative disorders. The continued research into Acacetin 7-O-methyl ether could provide insights into novel drug development and alternative therapeutic strategies.

Scutellarin is a bioactive flavonoid compound, which is derived primarily from the plant Scutellaria baicalensis and other species within the Scutellaria genus. As a naturally occurring phytochemical, Scutellarin exerts its effects through multiple biological pathways, including antioxidant, anti-inflammatory, and anti-apoptotic activities. Scutellarin operates by modulating several cellular signaling cascades. It inhibits oxidative stress-induced damage by scavenging free radicals and upregulating antioxidant defenses. Additionally, it exerts anti-inflammatory effects by downregulating the expression of pro-inflammatory cytokines, thus ameliorating inflammatory responses. Its influence on apoptosis pathways helps in preventing unwanted cellular death in tissues subjected to ischemic conditions. The primary applications of Scutellarin include its use in cardiovascular and neuroprotective research. In cardiovascular studies, it has shown promise in reducing ischemic damage and improving vascular function. In neurology, Scutellarin is being investigated for its potential to protect neurons from degeneration in conditions such as stroke and Alzheimer’s disease. Its multifaceted mode of action and plant-based origin make it a valuable subject of study in pharmacological and therapeutic research fields.

Inhibitor of HSP70 and HSP27 expression

Ketone phenol

Eriodictyol analytical standard provided with w/w absolute assay, to be used for quantitative titration.