Nucleotides
Nucleotides are organic compounds that serve as the building blocks of nucleic acids, essential for the formation of DNA and RNA. Each nucleotide is composed of a nitrogenous base, a sugar molecule, and one or more phosphate groups. These nucleotides join together to form long chains, creating the genetic material that carries and transmits genetic information in all living organisms. In this section, you will find a wide variety of nucleotides crucial for research in genetics, molecular biology, and biochemistry. They are fundamental for studying genetic processes, synthesizing nucleic acids, and developing diagnostic and therapeutic tools. At CymitQuimica, we offer high-quality nucleotides to support your scientific research and applications, ensuring precision and reliability in your experiments
Subcategories of "Nucleotides"
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6-Thio-9-(β-D-arabinofuranosyl)purine
CAS:6-Thio-9-(b-D-arabinofuranosyl)purine is a purine analog that inhibits the enzyme uridine phosphorylase, which is involved in the metabolism of uridine. It has been shown to inhibit the growth of L1210 cells and also to be effective against subcutaneous tumors in mice. 6-Thio-9-(b-D-arabinofuranosyl)purine is active against schistosomiasis in mice, with an LD50 of 1 mg/kg. This drug has also been shown to have potential antitumor activity and was able to inhibit the growth of human lymphocytes and leukocytes.Formula:C10H12N4O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:284.29 g/mol8-Nitroguanosine
CAS:8-Nitroguanosine is a nucleotide analogue that inhibits the activity of cyclic GMP in cells. It has been found to inhibit the growth of bacteria and cancer cells, as well as to stimulate the production of reactive oxygen species in brain cells. 8-Nitroguanosine has also been shown to inhibit the activity of cyclase enzymes in liver cells, which may be useful for treating liver disease. 8-Nitroguanosine is used as a chemical base for monoclonal antibodies that are used to study brain functions and pathogenic mechanisms.Formula:C10H12N6O7Purity:Min. 95%Molecular weight:328.24 g/mol2'-O-Methylcytidine-5'-monophosphate triethylammonium salt
CAS:2'-O-Methylcytidine-5'-monophosphate triethylammonium salt is a synthetic nucleoside that has been shown to be a substrate for DNA polymerase and an inhibitor of RNA synthesis. It has been used in the laboratory as a primer and as a biochemical tool to study viruses. 2'-O-Methylcytidine-5'-monophosphate triethylammonium salt is active against murine leukemia virus, but not against ciliated protozoan parasites such as Tetrahymena pyriformis. This compound has also been shown to inhibit the enzyme form of HIV reverse transcriptase and to be cytotoxic at high concentrations.Formula:C10H16N3O8P•C6H15NPurity:Min. 95%Color and Shape:PowderMolecular weight:438.41 g/mol2'-Deoxy-5-propargyloxyuridine
CAS:2'-Deoxy-5-propargyloxyuridine is a synthetic compound that inhibits the herpes simplex virus by inhibiting thymidylate synthase, an enzyme in the synthesis of DNA. It is used to study the growth rate of herpes virus and has been shown to inhibit murine leukemia L1210 and human l1210 cells at concentrations of 10-20 μg/mL. 2'-Deoxy-5-propargyloxyuridine has also been shown to have inhibitory activities against other viruses, such as polio virus and influenza virus. 2'-Deoxy-5-propargyloxyuridine inhibits biosynthesis by binding to enzymes involved in the synthesis of nucleic acids. The inhibitory dose for this compound is not yet known, but it has been shown to have an inhibitory effect on cell culture when preincubated with cells before infection with herpes simplex virus.Formula:C12H14N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:282.26 g/mol2'-Deoxyuridine
CAS:2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.Formula:C9H12N2O5Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:228.21 g/molb-Nicotinamide mononucleotide
CAS:b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.Formula:C11H15N2O8PPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:334.22 g/mol7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is a cytosolic small molecule that inhibits the activity of telomerase, an enzyme involved in the replication of chromosomes. It also has inhibitory effects on kinase domains and may be used to treat cancer. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt binds to human mitochondrial DNA and inhibits gene transcription by hybridizing with it. This results in the inhibition of dopamine production, which can be helpful for treating Parkinson's disease. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is structurally similar to 2'-deoxyadenosine 5'-triphosphate (dATP) and can be incorporated into DNA by phosphorylation to form a covalent bond that disrupts the dATP/ATP ratio. This causes cellular energy production to decrease andFormula:C11H17N4O13P3·xNaPurity:Min. 95%Molecular weight:506.19 g/molb-Nicotinamide adenine dinucleotide phosphate hydrate
CAS:Formula:C21H28N7O17P3·xH2OPurity:≥ 95.0%Color and Shape:White to off-white or light-yellow powder or crystalsMolecular weight:743.41 (anhydrous)5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å
5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å is a synthetic nucleoside that contains an acetyl group at the 5' position. The succinyl group has been added to the 3' position of the nucleoside and is bonded to a carrier molecule (2000 Å). This product is used as an activator in DNA synthesis, it also has antiviral and anticancer activities.Color and Shape:Powder2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate sodium, 100 mM aqueous solution
2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate sodium, 100 mM aqueous solution is a synthetic nucleoside that can be used as an antiviral and anticancer agent. The drug inhibits viral replication by inhibiting the synthesis of DNA. The drug also suppresses tumor growth by inhibiting the production of RNA and DNA in cancer cells.Formula:C10H18N3O14P3•NaxPurity:Min. 90 Area-%Color and Shape:Clear LiquidMolecular weight:497.18 g/mol2,6-Dichloro-7-deazapurine
CAS:Formula:C6H3Cl2N3Purity:>98.0%(HPLC)(N)Color and Shape:Light orange to Yellow to Green powder to crystalMolecular weight:188.01Cytidyl-3'-5'-uridine ammonium
CAS:Cytidyl-3'-5'-uridine ammonium salt is a nucleoside analog that is used as an antiviral and anticancer agent. Cytidyl-3'-5'-uridine ammonium salt inhibits the synthesis of DNA by inhibiting the activity of enzymes such as DNA polymerase, RNA polymerase, or reverse transcriptase. It also has antitumor properties and can be used to treat leukemia and other types of cancer. Cytidyl-3'-5'-uridine ammonium salt has been shown to be more potent than cytidyl-2',4',6'-triaminopyrimidine (CTAP) in inhibiting the growth of lymphocytic leukemia cells.Formula:C18H24N5O13P•NH3Purity:Min. 95%Color and Shape:PowderMolecular weight:566.42 g/molb-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium)
CAS:b-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium), or NADPH, is involved in redox reactions, where it acts as an electron donor. NADPH is essential for anabolic reactions, such as lipid and cholesterol biosynthesis, and fatty acid chain elongation. It also plays a significant role in antioxidation mechanisms, protecting cells from oxidative stress by neutralizing reactive oxygen species (ROS) and regenerating antioxidants like glutathioneFormula:C21H30N7O17P3·4C6H13NPurity:Min. 90 Area-%Color and Shape:Slightly Yellow PowderMolecular weight:1,142.12 g/mol2'-Deoxy-5-fluorouridine
CAS:Formula:C9H11FN2O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:246.19
