Nucleotides
Nucleotides are organic compounds that serve as the building blocks of nucleic acids, essential for the formation of DNA and RNA. Each nucleotide is composed of a nitrogenous base, a sugar molecule, and one or more phosphate groups. These nucleotides join together to form long chains, creating the genetic material that carries and transmits genetic information in all living organisms. In this section, you will find a wide variety of nucleotides crucial for research in genetics, molecular biology, and biochemistry. They are fundamental for studying genetic processes, synthesizing nucleic acids, and developing diagnostic and therapeutic tools. At CymitQuimica, we offer high-quality nucleotides to support your scientific research and applications, ensuring precision and reliability in your experiments
Subcategories of "Nucleotides"
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5'-O-DMT-2'-O-methyluridine
CAS:5'-O-DMT-2'-O-methyluridine (5'-OMeT) is a phosphoramidite building block of a modified nucleoside that is used in biological research. The stability of 5'-OMeT has been studied by thermal denaturation studies and found to be more stable than other analogues such as 6-azacytidine, 6-azauridine, and 6-azathymidine. This may be due to its increased resistance to endonucleolytic cleavage. 5'-OMeT has not shown any significant biological activity in vivo or in vitro.Formula:C31H32N2O8Purity:Min. 95%Color and Shape:White PowderMolecular weight:560.61 g/molNelarabine
CAS:Nelarabine is a drug that prevents the growth of cells by inhibiting the bcr-abl kinase, which is an intracellular target. This drug has been shown to be effective against pediatric patients with t-cell acute lymphoblastic leukemia and adults with chronic myeloid leukemia. Nelarabine has minimal toxicity in humans and is not toxic to healthy cells. It has been shown to have anti-inflammatory properties and may be used as a biomarker for autoimmune diseases. Nelarabine also inhibits angiogenesis, which may be due to its effects on nuclear DNA.Formula:C11H15N5O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:297.27 g/mol8-Aza-7-deaza-2''-deoxy-N2-DMF-5''-O-DMT-guanosine 3''-CE phosphoramidite
CAS:Formula:C43H53N8O7PPurity:≥ 95.0%Color and Shape:White or almost white powderMolecular weight:824.90Cytidine 5’-triphosphate disodium salt dihydrate
CAS:Formula:C9H16N3O14P3Na2Purity:≥ 96.0%Color and Shape:Colourless crystals or white powderMolecular weight:529.141-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-methyluracil
CAS:1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-methyluracil is a nucleoside analog for research applications. It contains a β-D-arabinofuranose sugar and the fluorine (F) substitution at the 2'-position enhances stability and improves resistance to enzymatic degradation. The 5-methyluracil base makes it structurally similar to thymidine, allowing it to be recognized by DNA polymerases and kinases.Formula:C10H13FN2O5Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:260.22 g/mol5-Chloro-2,4-Dihydroxypyridine
CAS:Formula:C5H4ClNO2Purity:98%Color and Shape:SolidMolecular weight:145.54382-Thiouridine
CAS:2-Thiouridine is a uridine derivative that acts as a precursor for protein synthesis. It is synthesized from 2-amino-5-thiazole carboxylic acid and uracil in two steps, first with the formation of 2-thiouridine monophosphate and then with the conversion to 2-thiouridine diphosphate. The synthesis of 2-thiouridine is catalyzed by the enzyme uridine phosphorylase, which converts it to uridine monophosphate. 2-Thiouridine has been shown to have immunomodulatory effects in cell culture systems and animal models. These effects are believed to be due to its ability to act as an inhibitor of fatty acid synthase, which generates fatty acids from acetyl CoA. This process prevents the production of prostaglandins and leukotrienes, thereby reducing inflammation.Formula:C9H12N2O5SPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:260.27 g/mol3-Deazauridine
CAS:Formula:C10H13NO6Purity:≥ 95.0%Color and Shape:White or off-white powderMolecular weight:243.212-Hydrazinoadenosine
CAS:2-Hydrazinoadenosine is an active analogue of adenosine. It is a potent agonist for the adenosine receptor subtypes A1 and A2A with high affinity. 2-Hydrazinoadenosine has been shown to inhibit cardiac contractility in animal models, as well as to produce hypotension, bradycardia, and bronchodilation in humans. This drug also has a functional effect on the heart by binding to adenosine receptors, which leads to the inhibition of catecholamine release. This drug is used clinically as an antiarrhythmic agent and a vasodilator in coronary artery disease.Formula:C10H15N7O4Purity:Min. 95%Color and Shape:PowderMolecular weight:297.27 g/molZebularine
CAS:Formula:C9H12N2O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:228.20Acetyl coenzyme A sodium salt
CAS:Acetyl-coenzyme A is an important intermediate in the metabolism of carbohydrates, fats, and proteins. It is a cytosolic molecule that is synthesized from Acetyl-CoA and ATP. The Michaelis-Menten kinetics describe the relationship between the concentration of acetyl-coenzyme A and the rate of its consumption. Acetyl co-enzyme A is found in many different tissues, including plants, animals, and humans. It has an important role in regulating cellular growth and differentiation by activating various enzymes involved in metabolic pathways. Acetyl CoA can be acetylated to form acetyl CoA carboxylic acid (ACC) which then turns into malonyl CoA through a series of reactions. Malonyl CoA then enters the Krebs cycle as a key intermediate for generating energy from fatty acids.Formula:C23H38N7O17P3S·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:809.57 g/mol2-Deoxy-5-vinyluridine
CAS:2-Deoxy-5-vinyluridine (5-VUdR) is a chemical compound that has been shown to cause a mutation in the DNA of herpes simplex virus. The compound is then incorporated into the viral DNA and replicated with each new cell division, leading to mutations in the sequence of its genome. This mutation can either be lethal or nonlethal, depending on how it affects the function of the virus. 5-VUdR has also been shown to affect cancer cells by inhibiting their growth and causing them to undergo apoptosis. This chemical compound also has an effect on animals and humans, as it alters body mass index and causes weight loss. It does this by preventing replication of DNA in cells that produce insulin, which leads to low insulin levels and decreased appetite.END>Formula:C11H14N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:254.24 g/mol5-Bromo-2'-deoxyuridine
CAS:Formula:C9H11BrN2O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:307.103'-O-Aminothymidine
CAS:3'-O-Aminothymidine is an isomer of thymidine, a nucleoside that is found in DNA and RNA. It has a neutral charge and belongs to the category of nucleosides. 3'-O-Aminothymidine is synthesized by the coupling of an amino group with a hydroxyl group. This reaction is efficient and can be used to produce dimers. 3'-O-Aminothymidine can also be used as a precursor for other nucleotides or as a synthetic intermediate in other chemical reactions.Formula:C10H15N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:257.24 g/mol
