Nucleotides
Nucleotides are organic compounds that serve as the building blocks of nucleic acids, essential for the formation of DNA and RNA. Each nucleotide is composed of a nitrogenous base, a sugar molecule, and one or more phosphate groups. These nucleotides join together to form long chains, creating the genetic material that carries and transmits genetic information in all living organisms. In this section, you will find a wide variety of nucleotides crucial for research in genetics, molecular biology, and biochemistry. They are fundamental for studying genetic processes, synthesizing nucleic acids, and developing diagnostic and therapeutic tools. At CymitQuimica, we offer high-quality nucleotides to support your scientific research and applications, ensuring precision and reliability in your experiments
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3-(3-Amino-3-carboxypropyl)uridine
CAS:3-(3-Amino-3-carboxypropyl)uridine is an uridine analog that is used in the study of protein synthesis. It can be used to determine the amino acid sequence of a protein, or to identify proteins with similar sequences. 3-(3-Amino-3-carboxypropyl)uridine can also be used to study enzymatic reactions, such as those involved in the synthesis of polypeptides. This molecule has been shown to produce disulfide bonds and form covalent bonds with other molecules. The three-dimensional structure of this molecule has been determined by NMR spectroscopy and X-ray crystallography.Formula:C13H19N3O8Purity:Min. 95%Color and Shape:PowderMolecular weight:345.31 g/mol2',3',5'-Tri-O-acetylguanosine
CAS:Formula:C16H19N5O8Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:409.36Thymidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:Thymidine-5'-triphosphate sodium salt is a modified nucleoside with anticancer properties. It is a high-quality, high-purity ribonucleoside that can be used as an activator for the synthesis of deoxyribonucleosides and phosphoramidites. Thymidine-5'-triphosphate sodium salt has antiviral activity, which is due to its ability to inhibit viral DNA replication and transcription. This compound also has the potential to be used in the treatment of cancer cells by inhibiting DNA synthesis and cell division.Formula:C10H17N2O14P3·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:482.17 g/molN2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine
CAS:Formula:C35H37N5O7Purity:>99.0%(HPLC)Color and Shape:White powder to crystalMolecular weight:639.716-Thioinosine 5'-monophosphate
CAS:6-Thioinosine 5'-monophosphate (6TIMP) is a hydrogen bond donor that possesses inhibitory properties against protein synthesis. It has been shown to have an anti-inflammatory effect and can be used for the treatment of inflammatory bowel disease. 6TIMP is also able to inhibit the bcr-abl kinase, which is implicated in the development of renal cell cancer. 6TIMP can be administered intravenously or orally and penetrates tissues well. The rate at which it enters cells is dependent on the transport rate, which is determined by its acidity. 6TIMP has been shown to cause DNA damage, leading to apoptosis and cell death in carcinoma cell lines. The mechanism of action appears to involve inhibition of cellular protein synthesis, acid formation, and DNA damage.Formula:C10H13N4O7PSPurity:Min. 95%Color and Shape:PowderMolecular weight:364.27 g/mol2'-Deoxyuridine-5'-monophosphate disodium salt
CAS:2'-Deoxyuridine-5'-monophosphate disodium salt (2DUMP) is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase. 2DUMP is a covalent inhibitor of thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate. This compound has been shown to be effective in treating squamous cell cancer and hyperproliferative diseases such as chronic myelogenous leukemia. 2DUMP is also used as an antiviral agent against HIV, herpes simplex virus, and varicella zoster virus. It has been shown to bind to benzalkonium chloride (BAK) in biological samples such as serum or plasma. 2DUMP binds to BAK through a covalent linkage between the 3' hydroxyl group on BAK and the phosphate group on 2DUMPFormula:C9H11N2O8PNa2Purity:Min. 95%Color and Shape:PowderMolecular weight:352.15 g/mol3'-Deoxyadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:3'-dATP, a nucleoside analog, which prevents RNA elongation past its incorporation site, potentially leading to truncated protein expression.Formula:C10H16N5O12P3Purity:Min. 95%Color and Shape:Colorless PowderMolecular weight:491.18 g/mol6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine
CAS:6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine is an energy metabolism agent that mimics cytokinin, a plant hormone. It has been shown to affect the angiogenic process and induce apoptosis in HL60 cells through the pro-apoptotic protein Bax. 6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine has also been used as a model system to study the structure of dna, which is important for understanding how it replicates. 6-(3,3-Dimethylallylamino)-9-(b-D-ribofuranosyl)purine is structurally similar to adenosine and binds to the A3 receptor with high affinity. This drug is active as an analogue of adenosine and may be useful for treating diseases such as heart disease or diabetes.Formula:C15H21N5O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:335.37 g/molN6-Succinyl adenosine
CAS:Formula:C14H17N5O8Purity:≥ 96.0% (anhydrous basis)Color and Shape:White to off-white powderMolecular weight:383.313'-Amino-3'-deoxy-5'-O-DMT-thymidine
CAS:3'-Amino-3'-deoxy-5'-O-DMT-thymidine is a specifically designed building block for introducing a 3'-amino group into oligonucleotides, primarily at the 3' terminus. The DMT protecting group facilitates incorporation during standard solid-phase synthesis, and the 3'-amino group provides a versatile handle for post-synthetic modifications and conjugations.Formula:C31H33N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:543.61 g/molL-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester, hydrochloride (1:1)
CAS:Formula:C14H23ClN6O5Purity:98%Color and Shape:SolidMolecular weight:390.82261-(α-D-Ribofuranosyl)uracil
CAS:1-(α-D-Ribofuranosyl)uracil is a nucleoside analog made up of a uracil attached to a ribose sugar at the 1-position, with the sugar in the α configuration. This compound is of interest in biochemistry research and nucleoside chemistry, especially when studying stereochemistry or synthesizing analogs.Formula:C9H12N2O6Purity:(¹H-Nmr) Min. 95 Area-%Color and Shape:PowderMolecular weight:244.2 g/mol5'-Azido-5'-deoxythymidine
CAS:5'-Azido-5'-deoxythymidine is a synthetic analogue of thymidine. The compound has been synthesised and fluorescently labelled with ferrocene. 5'-Azido-5'-deoxythymidine is not cytotoxic to cancer cells, but it is shown to be an effective inhibitor of DNA synthesis by binding to the enzyme DNA polymerase. This causes a decrease in the rate of DNA synthesis and thus inhibits cancer cell growth.Formula:C10H13N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:267.24 g/mol5'-O-Tritylthymidine
CAS:5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.Formula:C29H28N2O5Purity:Min. 95%Molecular weight:484.54 g/molN6-Hydroxymethyladenosine
CAS:Please enquire for more information about N6-Hydroxymethyladenosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C11H15N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:297.27 g/mol2,6-Dichloropurine
CAS:Formula:C5H2Cl2N4Purity:>97.0%(T)(HPLC)Color and Shape:White to Light yellow to Dark green powder to crystalMolecular weight:189.00N-Pyrrolo-2'-deoxycytidine
CAS:N-Pyrrolo-2'-deoxycytidine is a nucleoside analog that is used in the laboratory as a template for DNA synthesis. It has been shown to be an effective inhibitor of human pathogens. N-Pyrrolo-2'-deoxycytidine binds to DNA and prevents replication by interfering with the binding of the enzyme polymerase to the template strand, which leads to denaturation of the complementary strand and blocking of DNA elongation. This drug has been shown to bind specifically to sequences that are unpaired in duplexes, such as single-stranded telomeres. N-Pyrrolo-2'-deoxycytidine can also be used as a fluorescence probe for detecting dsDNA duplexes.Formula:C12H15N3O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:265.27 g/mol2'-Deoxy-5'-O-DMT-cytidine
CAS:2'-Deoxy-5'-O-DMT-cytidine is an organic compound. It is a synthetic, combinational and amine nitrogen containing heterocyclic compound that is used in organic synthesis. This chemical is also used as a building block for the synthesis of heterocyclic compounds with other functional groups such as thionyl, formulae, chlorides and hydrogen atoms.Formula:C30H31N3O6Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:529.58 g/mol2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution
CAS:2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution, is a synthetic nucleotide analog. It has potential application in antiviral research, particularly for studying RNA-dependent RNA polymerase (RdRP) activity in RNA viruses. It mimics the natural cytidine triphosphate (CTP) but includes a 2'-C-methyl modification on the ribose sugar.Formula:C10H18N3O14P3·4C6H15NPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:901.94 g/mol5''-Iodo-5''-deoxyguanosine
CAS:Formula:C10H12IN5O4Purity:≥ 95.0%Color and Shape:White to off-white powderMolecular weight:393.141H-Purin-6-amine, monohydrochloride, hydrate (2:1)
CAS:Formula:C10H14Cl2N10OPurity:95%Color and Shape:SolidMolecular weight:361.19056000000006N6-(6-Aminohexyl)-2''-deoxyadenosine
CAS:Formula:C16H26N6O3Purity:≥ 90.0%Color and Shape:Clear, pale yellow solid or viscous liquidMolecular weight:350.423'-O-Propargylcytidine
3'-O-Propargylcytidine is a monophosphate nucleoside that belongs to the group of synthetic, novel nucleosides and deoxyribonucleosides. It is a modified form of cytidine with an extra methyl group attached to the 3' position of the ribose sugar. 3'-O-Propargylcytidine has been shown to inhibit cancer cells by binding to DNA and preventing transcription and replication. This compound also inhibits virus replication and has antiviral properties. 3'-O-Propargylcytidine is highly pure and high quality, which makes it a good candidate for use in pharmaceuticals or other applications requiring high purity.Formula:C12H15N3O5Purity:(%) Min. 97%Color and Shape:PowderMolecular weight:281.26 g/molC2-Methyladenosine
CAS:C2-Methyladenosine is a x-ray crystal structure of the mutant strain of Mycobacterium tuberculosis that has an efficient method for binding to the substrate. The uptake of C2-methyladenosine by the wild type strain was found to be at least four times higher than that of adenosine. The analog was also shown to have pharmacokinetic properties in fat cells, which leads to a decrease in ATP levels.Formula:C11H15N5O4Purity:Min. 96 Area-%Color and Shape:White PowderMolecular weight:281.27 g/mol5-Nitrouracil
CAS:Formula:C4H3N3O4Purity:>99.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:157.092',5'-Dideoxyguanosine
CAS:2',5'-Dideoxyguanosine is a modified nucleoside analog of guanosine, one of the four natural nucleosides found in RNA and DNA. This synthetic molecule has hydroxyl groups removed from the 2' and 5' positions of the sugar component, which alters its ability to participate in nucleic acid synthesis.Formula:C10H13N5O3Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:251.25 g/mol5'-O-DMT-a-thymidine
5'-O-DMT-a-thymidine is a modified nucleoside that is used in the synthesis of DNA and RNA. This product is a high quality and pure monophosphate, which has been modified to reduce its potential for activation by phosphatases. It is suitable for use in anticancer drugs and antiviral agents.Formula:C31H32N2O7Purity:Min. 95%Molecular weight:544.6 g/molN1-Methylpseudouridine 5'-Triphosphate Sodium Salt (ca. 100mM in Water) [for transcription] [for Molecular Biology]
CAS:Formula:C10H17N2O15P3·xNaPurity:min. 95.0 area%(HPLC)Color and Shape:Colorless to Almost colorlessclear liquid5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
CAS:Formula:C17H20N4O2Molecular weight:312.374-Thiothymidine
CAS:Formula:C10H14N2O4SPurity:≥ 98.0%Color and Shape:Off-white to yellow powderMolecular weight:258.3Adenine, USP grade
CAS:Formula:C5H5N5Purity:98.0 - 102.0 % (dried basis)Color and Shape:White to off-white crystalline powderMolecular weight:135.132'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a nucleoside with anticancer properties. It is a phosphoramidite, which is an analog of the natural nucleotide guanosine, where the 2'-hydroxyl group has been replaced by a methylene group. This compound is used in DNA synthesis and RNA synthesis. It can be used as a monophosphate or diphosphate. It also has antiviral and anti-inflammatory activities, as well as N2-methylamino moiety that can be used for the treatment of cancer and inflammatory diseases such as arthritis.Formula:C11H15N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:281.27 g/mol5-Methylcytidine-5'-monophosphate
CAS:5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.Formula:C10H16N3O8PPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:337.22 g/mol7-Deazaguanosine
CAS:7-Deazaguanosine is a low energy analog of guanosine that has been shown to be activated by trifluoroacetic acid, which is a chemical reagent that can be used for the activation of nucleosides. 7-Deazaguanosine is used in the treatment of human serum and urine viruses such as hepatitis B virus, herpes simplex virus, and cytomegalovirus. The compound has also been shown to have receptor agonism activity on toll-like receptors. 7-Deazaguanosine has been shown to have antiviral effects against HIV and influenza A (H1N1). 7-Deazaguanosine binds at the viral receptor site and blocks the entry process into cells. This drug also stimulates macrophages to produce cytokines, which are proteins that regulate immune responses.Formula:C11H14N4O5Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:282.26 g/mol8-Bromocyclic adenosine diphosphate ribose sodium salt
CAS:Formula:C15H20BrN5O13P2Molecular weight:620.206-Chloromethyluracil
CAS:Formula:C5H5ClN2O2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:160.56Cytidine 5'-monophosphate disodium salt
CAS:Formula:C9H12N3Na2O8PPurity:97%Color and Shape:SolidMolecular weight:367.1602
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