Nucleotides
Nucleotides are organic compounds that serve as the building blocks of nucleic acids, essential for the formation of DNA and RNA. Each nucleotide is composed of a nitrogenous base, a sugar molecule, and one or more phosphate groups. These nucleotides join together to form long chains, creating the genetic material that carries and transmits genetic information in all living organisms. In this section, you will find a wide variety of nucleotides crucial for research in genetics, molecular biology, and biochemistry. They are fundamental for studying genetic processes, synthesizing nucleic acids, and developing diagnostic and therapeutic tools. At CymitQuimica, we offer high-quality nucleotides to support your scientific research and applications, ensuring precision and reliability in your experiments
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5'-Deoxythymidine
CAS:5'-Deoxythymidine is a nucleoside analog with low-energy electrons. This drug inhibits the synthesis of DNA by binding to the ribonucleotide reductase enzyme and preventing the conversion of ribonucleotides to deoxyribonucleotides. 5'-Deoxythymidine has been shown to inhibit cell growth in tumor cell lines, which may be due to its ability to interfere with mirna-mediated gene expression. This drug also has a kinetic effect on regulatory proteins, such as cyclin-dependent kinases, that are involved in the regulation of cell cycle progression.Formula:C10H14N2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:226.23 g/mol3-Hydroxy nevirapine
CAS:Formula:C15H14N4O2Purity:≥ 98.0%Color and Shape:Off-white to light yellow solidMolecular weight:282.305-Ethynyl-2'-deoxycytidine
CAS:Formula:C11H13N3O4Purity:>98.0%(N)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:251.242'-O-Methylinosine
CAS:2'-O-Methylinosine is a nucleoside that is structurally related to inosine. It has been shown to induce apoptotic cell death in HIV-infected cells by inhibiting the synthesis of rRNA and by inhibiting the activity of the transcriptase enzyme. 2'-O-Methylinosine has also been shown to inhibit the replication of RNA viruses, such as herpes simplex virus and cytomegalovirus, and it can be used as an experimental model for studying apoptosis. 2'-O-Methylinosine can be synthesized from inosine using a chromatographic method that utilizes hydroxylamine. The chemical structure of this nucleoside is amphipathic, which allows it to bind both DNA and RNA strands.Formula:C11H14N4O5Purity:Min. 99 Area-%Color and Shape:White PowderMolecular weight:282.25 g/molFialuridine 5'-monophosphate
CAS:Fialuridine 5'-monophosphate is an analog of fialuridine, a drug used to treat HIV. Fialuridine 5'-monophosphate inhibits mitochondrial DNA synthesis by inhibiting hepg2 in the mitochondria and blocks the conversion of uracil to thymine in nuclear DNA. The inhibition of these two processes prevents viral replication and cell division. Fialuridine 5'-monophosphate also has antioxidant properties that protect cells from oxidative damage induced by reactive oxygen species. This drug may be beneficial for cancer treatment as well as hepatitis C or herpes simplex virus infection.Formula:C9H11FIN2O8PPurity:Min. 95%Molecular weight:452.07 g/mol2'-Deoxy-5-fluorouridine
CAS:2'-Deoxy-5-fluorouridine is a nucleoside analog that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It has been shown to inhibit the growth of cancer cells and induce apoptosis in vivo. 2'-Deoxy-5-fluorouridine has also been shown to inhibit tumor growth in animal models by inhibiting the production of reactive oxygen species and upregulating tumor suppressor genes, such as p53. This drug also has inhibitory effects on enzymes that are involved in cell proliferation, such as protein kinase C and tyrosine kinases. 2'-Deoxy-5-fluorouridine is metabolized by water vapor, so it must be administered with a humidifier or nebulizer. 2'-Deoxy-5-fluorouridine may cause side effects such as nausea, vomiting, and diarrhea.Formula:C9H11FN2O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:246.2 g/molThymidylyl-(3''-5'')-2''-deoxyadenosine ammonium salt
CAS:Formula:C20H24N7O10PNH3Molecular weight:570.45β-Nicotinamide adenine dinucleotide phosphate disodium salt
CAS:Formula:C21H26N7Na2O17P3·xH2OPurity:≥ 93.0%Color and Shape:Off-white to light-yellow crystalline powderMolecular weight:787.37 (anhydrous)Cytidine
CAS:Formula:C9H13N3O5Purity:≥ 99.0%Color and Shape:White or almost white powder or crystalsMolecular weight:243.22b-Nicotinamide-adenine dinucleotide phosphate tetrasodium salt, reduced
CAS:Formula:C21H26N7Na4O17P3·xH2OPurity:≥ 90.0%Color and Shape:White to pale yellow crystalline powderMolecular weight:833.35 (anhydrous basis)L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, hydrochloride (1:1)
CAS:Formula:C13H21ClN6O4Purity:97%Color and Shape:SolidMolecular weight:360.79662,4-Diamino-6-hydroxypyridine sulphate
CAS:2,4-Diamino-6-hydroxypyridine sulphate is a nucleoside for use in research applicationsFormula:C4H6N4O•(H2SO4)xPurity:Min. 95%Color and Shape:PowderMolecular weight:224.2 g/molCytidine Sulfate
CAS:Formula:C18H26N6O10·H2SO4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:584.513,3'',5-Triiodo-L-thyronine sodium salt
CAS:Formula:C15H11I3NNaO4Purity:95.0 - 101.0 % (dried basis)Color and Shape:Off-white to tan or pale pink-beige powderMolecular weight:672.961-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine
CAS:1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.Formula:C24H24N4O6Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:464.48 g/mol5′-O-DMT-LNA N-dmf guanosine
CAS:5′-O-DMT-LNA N-dmf guanosine is a modified nucleoside that has anticancer, antiviral, and anti-inflammatory activities. It binds to the ribonucleotide reductase enzyme, which is an enzyme required for the production of new DNA and RNA. This binding prevents the synthesis of new DNA and RNA in cells, leading to cell death. 5′-O-DMT-LNA N-dmf guanosine has been shown to be active against cancer cells in vitro and in vivo. In addition, it also inhibits replication of human immunodeficiency virus type 1 (HIV) by binding to reverse transcriptase (RT), which is an enzyme critical for HIV replication.Formula:C35H36N6O7Purity:Min. 95%Molecular weight:652.7 g/mol2'-C-Methyladenosine
CAS:Antiviral compound; inhibitor of viral RNA replicationFormula:C11H15N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:281.27 g/molAcetamide,N-[9-[[2-(acetyloxy)-1-[(acetyloxy)methyl]ethoxy]methyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-
CAS:Formula:C15H19N5O7Purity:97%Color and Shape:SolidMolecular weight:381.3407
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