
Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Products of "Nucleosides"
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2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil
CAS:2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a novel and high purity anticancer and antiviral agent. It is an activator that has been shown to exhibit antineoplastic activity in vitro. The compound also inhibits the formation of RNA and DNA, which are necessary for the replication of cells. 2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a modified nucleoside that has been synthesized by phosphoramidite chemistry. This product can be used for research purposes and as a starting material for the synthesis of other compounds with similar structures.Formula:C11H12N2O7Purity:Min. 95%Molecular weight:284.22 g/mol3'-Amino-N6-benzoyl-2',3'-dideoxy-5'-O-DMT-adenosine
A valuable chemical tool for synthesizing modified oligonucleotides with specific functionalities at the 3' end, primarily used in oligonucleotide synthesis.Formula:C38H36N6O5Purity:Min. 95%Molecular weight:656.73 g/mol2'-Deoxy-5-methyl-isocytidine triphosphate
2'-Deoxy-5-methyl-isocytidine triphosphate (2'-DMI-dTP) is a novel nucleoside that is synthesized by phosphoramidite chemistry. 2'-DMI-dTP has antiviral and anticancer activities, and can be used for the treatment of hepatitis B virus (HBV) and human papillomavirus (HPV). It has shown protective effects in animal models of HBV infection. 2'-DMI-dTP inhibits HBV replication by inhibiting DNA synthesis. In addition, it decreases levels of reactive oxygen species in cells treated with HBV. 2'-DMI-dTP also inhibits HPV replication through inhibition of DNA synthesis, which may lead to cancer prevention or treatment. 2'-DMI-dTP may be a useful drug candidate for the treatment of other viral infections such as influenza A virus and HIV type 1.Purity:Min. 95%N6-Benzoyl-2'-O-methyladenosine
CAS:N6-Benzoyl-2'-O-methyladenosine is a nucleoside that is chemically synthesized. It has been shown to be an inhibitor of the polyhedrosis virus, which causes an infectious disease in silkworms. N6-Benzoyl-2'-O-methyladenosine also inhibits viral replication by interfering with the synthesis of messenger RNA. This compound can be used as a silver nitrate or silver salt prodrug for treating diseases caused by viruses and bacteria. This drug is not active against DNA viruses because it does not possess phosphate groups on its structure.Formula:C18H19N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:385.37 g/mol3-Deaza-4’-C-methyluridine
CAS:3-Deaza-4’-C-methyluridine is an activator that can be used in the treatment of cancer. It is a synthetic nucleoside that has been modified to inhibit viral replication. 3-Deaza-4’-C-methyluridine can also be used in antiviral therapy, as it inhibits the synthesis of viral DNA and RNA. This antibacterial agent is a novel nucleoside that has been shown to have high purity and high quality. 3-Deaza-4’-C-methyluridine was first isolated from calf thymus DNA.Formula:C11H15NO6Purity:Min. 95%Molecular weight:257.24 g/mol3'-Amino-2',3'-dideoxy-5-methylcytidine
CAS:3'-Amino-2',3'-dideoxy-5-methylcytidine is an antiviral agent that has been shown to inhibit the replication of viruses in cell culture. It also inhibits the synthesis of DNA, RNA, and proteins. This drug has been used in vivo studies on animals and humans. 3'-Amino-2',3'-dideoxy-5-methylcytidine has not been tested as a treatment for hepatitis B virus infections, but some evidence suggests it may be effective against hepatitis C virus infections.Formula:C10H16N4O3Purity:Min. 95%Molecular weight:240.26 g/molCytidine 5'-diphosphocholine
CAS:Cytidine 5'-diphosphocholine is a nucleotide that is a precursor of uridine 5'-triphosphate and cytidine 5'-monophosphate, which are important for DNA synthesis. Cytidine 5'-diphosphocholine is used in the preparation of samples for experiments. This compound has been shown to induce neuronal death in an experimental model. It has also been shown to inhibit polymerase chain reactions and affect the activity of enzymes such as alpha-7 nicotinic acetylcholine receptors and glutamate decarboxylase. Cytidine 5'-diphosphocholine has been found to have no effect on basic fibroblast cells, but it does have physiological effects on human erythrocytes.Formula:C14H26N4O11P2Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:488.32 g/mol4-(2-Thienyl)-2-pyrimidinethiol
CAS:Please enquire for more information about 4-(2-Thienyl)-2-pyrimidinethiol including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C8H6N2S2Purity:Min. 95%Molecular weight:194.28 g/mol7-Methyl-6-thioguanosine inner salt
CAS:7-Methyl-6-thioguanosine inner salt is a compound that inhibits the activity of creatine kinase and phosphatase, which are enzymes involved in energy metabolism. It also binds to actin filaments and prevents their depolymerization. The binding mechanism of 7-methyl-6-thioguanosine inner salt is believed to be due to its ability to form disulfide bonds with cysteine residues on the surface of the enzyme. This inhibition has been shown to reduce the ATP production in mammalian cells and has been used as a model system for studying cellular processes.Formula:C11H15N5O4SPurity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:313.33 g/mol8-Aminoguanosine
CAS:8-Aminoguanosine is a synthetic purine nucleoside that inhibits DNA synthesis. It has been shown to inhibit the proliferation of HL-60 cells, which are a model for human monocytes and neutrophils. 8-Aminoguanosine has been shown to bind to the template strand of DNA and inhibit the incorporation of deoxyribonucleotide triphosphates into the newly synthesized strand. This binding prevents DNA replication by preventing access to the template strand of DNA. 8-Aminoguanosine inhibits cyclin D2, an enzyme required for cell division, at concentrations as low as 0.1 mM, and it also inhibits microtubule assembly. 8-Aminoguanosine has shown in vitro activity against various tumor cell lines including Molt-4 and MCF7 cells, and in vivo activity in a mouse model against C3H/HeJ mice transplanted with Lewis lung carcinoma cells.Formula:C10H14N6O5Purity:Min. 95%Color and Shape:PowderMolecular weight:298.26 g/mol[(2S,6R)-6-{N2-(Isobutyryl)-O6-(diphenylcarbomoyl)guanin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{N2-(Isobutyryl)-O6-(diphenylcarbamoyl)guanin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethylphosphoramidochloridate is a novel antiviral agent that is structurally related to the nucleoside analogues. It is synthesized by reacting an N2-(isobutyryl)O6-(diphenylcarbamoyl)guanin with 2,6-bis(trityl)morpholine and methyl dimethyl phosphite in dichloromethane. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), HSV type 2 (HSV2), and cytomegalovirus (CMV). [(2S,6R)-6-{N2-(Isobutyryl)-OFormula:C48H48ClN8O6PPurity:Min. 95%Molecular weight:899.37 g/mol5'-O-Tosylthymidine
CAS:5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.Formula:C17H20N2O7SPurity:Min. 95%Molecular weight:396.42 g/mol2'-C-Methylguanosine 5'-monophosphate triethyl ammonium salt - Aqueous solution
2'-C-Methylguanosine 5'-monophosphate triethyl ammonium salt - Aqueous solution is a synthetic nucleotide analog for use in researchFormula:C11H16N5O8P·C12H32N2Purity:Min. 95%Color and Shape:Clear liquid.Molecular weight:581.64 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt
N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt is a modified nucleotide that has been shown to have anticancer and antiviral activity. N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt inhibits the synthesis of viral DNA and also inhibits the production of DNA in tumor cells. This compound is a phosphoramidite, which is an activated ester of a nucleoside with a phosphate group. The active form of this drug is adenosine triphosphate (ATP), which acts as an activator for DNA synthesis, leading to the production of deoxyribonucleosides and monophosphate, which are necessary for DNA replication.Purity:Min. 95%2'-Deoxycytidine 3'-O-L-valinyl ester
CAS:Please enquire for more information about 2'-Deoxycytidine 3'-O-L-valinyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C14H22N4O5Purity:Min. 95%Molecular weight:326.35 g/molN4-Acetyl-2'-O-tert-butyldimethylsilylcytidine
CAS:N4-Acetyl-2'-O-tert-butyldimethylsilylcytidine is a novel nucleoside that has been extensively studied for its anticancer and antiviral properties. It is a modified nucleoside that inhibits the production of DNA, RNA, and protein. This product is also used as an activator in the synthesis of oligonucleotides. N4-Acetyl-2'-O-tert-butyldimethylsilylcytidine can be used in vitro to study the effects of different cancer cells on DNA replication. It has been shown to inhibit the growth of human leukemia cells in culture.Formula:C17H29N3O6SiPurity:Min. 95%Color and Shape:PowderMolecular weight:399.51 g/mol5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å
5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å is a nucleoside, modified with succinyldiimidazopropylcarbodiimide. It is an activator of phosphoramidites and is used in the synthesis of DNA and RNA. 5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å has shown anticancer and antiviral properties in vitro.Purity:Min. 95%6-(2-Deoxy-3,5-di-O-toluoyl-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one
CAS:6-(2-Deoxy-3,5-di-O-toluoyl-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is a nucleoside analog that inhibits the activity of DNA polymerase and RNA polymerase. It has been shown to be active against human leukemia cells and is currently being used in clinical trials for cancer treatment. 6-(2-Deoxy-3,5-diOtoluoyl b D ribofuranosyl)-3,4 dihydro 8H pyrimido[4,5 c] [1,2]oxazin 7 one is a novel nucleoside analog that has been shown to be effective against both DNA and RNA viruses.Formula:C27H27N3O7Purity:Min. 95%Molecular weight:505.52 g/mol2'-Deoxy-2',2'-difluoroguanosine
CAS:2'-Deoxy-2',2'-difluoroguanosine (DFG) is an analog of guanosine that has been used to study the effect of guanylate kinase on cellular proliferation. This compound has also been shown to have a cytotoxic effect on leukemia cells. DFG has been shown to inhibit the growth of cancer cells and induce apoptosis in HL-60 leukemia cells. It has also been shown to inhibit the synthesis of DNA, RNA, and proteins. These effects are due to inhibition of guanylate kinase activity and may be related to its ability to cause the release of intracellular calcium ions.Formula:C10H11F2N5O4Purity:Min. 95%Molecular weight:303.22 g/molN2-Isobutyrylguanosine
CAS:Formula:C14H19N5O6Color and Shape:White to Almost white powder to crystalMolecular weight:353.343'-Deoxythymidine
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C10H14N2O4Molecular weight:226.23N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine
CAS:N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine is a novel nucleoside phosphoramidite with antiviral and anticancer activities. It is synthesized from 2'-deoxycytidine and 4-aminobenzoyl chloride in the presence of tetrazole as a catalyst. The cytidine moiety of N4-benzoyl-2'-deoxy-3'-O-DMT-cytidine is activated by diphosphate, which leads to phosphorylation. This nucleotide has shown potential in inhibiting cancer cell growth and may be used for treatment of leukemia, lymphomas, and myeloma.Formula:C37H35N3O7Purity:Min. 95%Molecular weight:633.69 g/mol1-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-iodouracil
CAS:1-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-iodouracil is a nucleoside analog with antiviral properties. It consists of a modified uracil base (5-iodouracil) attached to a fluorinated arabinofuranosyl sugar moiety. In cell culture, it inhibits the replication of varicella-zoster virus, herpes simplex virus type 1 and 2 and cytomegalovirus.Formula:C9H10FIN2O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:372.09 g/mol9-(b-D-Arabinofuranosyl)-8-chloroadenine
CAS:9-(b-D-arabinofuranosyl)-8-chloroadenine is a deoxyribonucleoside that is structurally related to adenosine. It has antiviral properties and has been shown to be active against herpes virus, influenza A virus, and cytomegalovirus. 9-(b-D-Arabinofuranosyl)-8-chloroadenine is an activator of cellular DNA polymerase δ and has been shown to inhibit the replication of HIV in human T lymphocytes. 9-(b-D-Arabinofuranosyl)-8-chloroadenine also inhibits the proliferation of tumor cells and is being investigated as a potential chemotherapeutic agent for cancer treatment.Purity:Min. 95%2,3'-Anhydrouridine 5'-CE phosphoramidite
2,3'-Anhydrouridine 5'-CE phosphoramidite is a novel modified phosphoramidite that can be used in the synthesis of ribonucleosides and DNA. It has antiviral activity, and is being studied as an anticancer drug. 2,3'-Anhydrouridine 5'-CE phosphoramidite has been shown to inhibit the replication of HIV-1 and herpes simplex virus type 1 (HSV-1). The nucleoside analogs are being studied for their potential use in chemotherapy.Formula:C18H27N4O6PPurity:Min. 95%Molecular weight:426.41 g/molN6-Carbamoylthreonyladenosine sodium salt
CAS:N6-Carbamoylthreonyladenosine sodium salt is a fatty acid that is found in the bacterial cell wall. It has been shown to be an essential component of the cell wall for Gram-positive and Gram-negative bacteria. N6-Carbamoylthreonyladenosine sodium salt has been used to study the mechanism of protein synthesis in bacteria, especially how enzymes are involved in this process. Chemical biology studies have shown that this molecule can bind to DNA and inhibit bacterial growth. The crystal structure of N6-Carbamoylthreonyladenosine sodium salt has also been determined using x-ray diffraction data. This molecule inhibits the binding of proteins to DNA, which prevents transcription and replication. The reaction mechanism involves hydrogen bonding between the oxygen atoms on N6-Carbamoylthreonyladenosine sodium salt and divalent metal ions such as magnesium or zinc, which are required for protein synthesis.Formula:C15H19N6O8·NaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:434.34 g/mol3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine
3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine is a novel, activator, ribonucleosides, deoxyribonucleosides, diphosphate, phosphoramidites, modified nucleosides. It can be used as an anticancer and antiviral agent.Formula:C32H31FN2O8Purity:Min. 95%Molecular weight:590.6 g/mol2'-O-tert-Butyldimethylsilyl-O4-(4-chlorophenyl)-5'-O-DMT-uridine 3'-CE-phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-O4-(4-chlorophenyl)-5'-O-DMT-uridine 3'-CE-phosphoramidite is a nucleoside that is used in the synthesis of DNA. It is a novel synthetic nucleotide with antiviral and anticancer properties. The phosphoramidite has been modified to give it high purity, and the monophosphate form has been synthesized. This nucleotide is synthesized through the use of an Activator, which activates the 2' position of the sugar moiety on the 5' phosphate terminus. This product is of high quality due to its high purity and novel synthetic nature.Formula:C51H64CIN4O9PSPurity:Min. 95%Molecular weight:971.6 g/mol5'-O-DMT-2'-O-methylinosine
CAS:Please enquire for more information about 5'-O-DMT-2'-O-methylinosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C32H32N4O7Purity:Min. 95%Molecular weight:584.63 g/mol2',3'-O-Isopropylideneguanosine
CAS:2',3'-O-Isopropylideneguanosine is a nucleoside for use in research applicationsFormula:C13H17N5O5Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:323.31 g/molUridine-5-oxyacetic acid methyl ester
CAS:Uridine-5-oxyacetic acid methyl ester is a modified nucleotide that is an intermediate in the biosynthesis of uridine. This molecule can be synthesized from 5-hydroxymethyluridine and malonic acid by a methyltransferase. Uridine-5-oxyacetic acid methyl ester can also be obtained from the metabolism of deoxyribose. Analysis of this molecule is possible with spectrometric, mass spectrometric, and chemical structures methods. It has been shown to have a function in translation and protein synthesis. The chemical structure of uridine-5-oxyacetic acid methyl ester has been determined to be guanosine-3',5'-bis(2'-carboxyethyl)phosphate, which is different from that found in DNA or RNA.Formula:C12H16N2O9Purity:Min. 95%Color and Shape:PowderMolecular weight:332.26 g/mol5-Bromo-2'-deoxycytidine
CAS:5-Bromo-2'-deoxycytidine is a synthetic nucleoside analogue that is used to treat diabetic neuropathy. It is structurally similar to cytidine, and inhibits the enzyme DNA polymerase by intramolecular catalysis. This causes deamination of the 5-bromo group, which prevents further synthesis of DNA. 5-Bromo-2'-deoxycytidine has been shown to be effective in vivo in a mouse model for inflammatory bowel diseases, including colitis and eosinophilic enteritis. The drug was also found to inhibit the production of Eosinophil peroxidase from HL-60 cells in vitro.Formula:C9H12BrN3O4Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:306.11 g/molN1-Methyladenosine-5’-monophosphate triethylammonium salt
CAS:N1-Methyladenosine-5’-monophosphate is a RNA modified nucleotide.Formula:C11H16N5O7P·xC6H15NPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:361.25 g/mol5'-Phosphoguanylyl-(3'->5')-guanosine sodium
CAS:pGpG, linear diguanylate, is the first phosphodiesterase-catalyzed hydrolysis product of cylic di-GMP (c-diGMP). c-diGMP has been identified as a novel second messenger in bacteria that triggers various physiological changes such as virulence gene expression or cell differentiationFormula:C20H26N10O15P2·xNaPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:708.43 g/molAdenosine 5'-phosphosulfate triethylamine salt
Please enquire for more information about Adenosine 5'-phosphosulfate triethylamine salt including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C16H30N6O10PSPurity:Min. 95%Molecular weight:529.46 g/mol5,6-Dihydro-2'-deoxyuridine
CAS:5,6-Dihydro-2'-deoxyuridine (dUrd) is a pyrimidine nucleoside that is an important component of DNA. It is phosphorylated by deoxyribonucleoside kinase to form dUrd monophosphate. This compound has been shown to inhibit the activity of catalase and other enzymes that hydrolyze hydrogen peroxide, indicating it may have antiviral properties. The enzyme activities of 5,6-dihydro-2'-deoxyuridine on simplex virus type 1 have been studied in vitro using lymphoblastoid cells. In these studies, the compounds was found to inhibit viral growth and terminate replication. 5,6-Dihydro-2'-deoxyuridine also inhibits the synthesis of DNA by inhibiting oxidative deamination reactions and termini formation in herpes simplex virus type 1. This drug has also been shown to inhibit amine oxidases in hepFormula:C9H14N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:230.22 g/molCyclic di-adenosine monophosphate sodium salt
CAS:Cyclic di-adenosine monophosphate sodium salt (c-di-AMP) is a cyclic nucleotide that is structurally similar to its natural counterpart, Adenosine 5'-triphosphate. It binds to the Toll-like receptor 4 (TLR4) and blocks the activation of TLR4 by lipopolysaccharide, thereby inhibiting the downstream inflammatory response. c-di-AMP also inhibits the production of proinflammatory cytokines such as TNFα, IL1β, and IL6 in vitro. c-di-AMP has shown anti-inflammatory properties in vivo and can be used for the treatment of infectious diseases.Formula:C20H24N10O12P2·xNaPurity:Min. 95%Molecular weight:658.41 g/mol2'-Deoxy-5-methylcytidine HCl
CAS:2'-Deoxy-5-methylcytidine HCl is a cytidine derivative that is used in the synthesis of DNA. It has been shown to have anticancer and antiviral properties, as well as being a synthetic activator for RNA polymerase. The chemical name for 2'-deoxy-5-methylcytidine HCl is 5'-[(2-bromoacetyl)amino]-2'-deoxyuridine 5'-O-(1,3-dithiole-2-thiocarbonyl)-3',5' -diiodo-. It belongs to the class of deoxyribonucleosides. This product may be used in applications such as DNA synthesis, modification of DNA, and antiviral treatment.Formula:C10H15N3O4·HClPurity:Min. 95%Color and Shape:White PowderMolecular weight:277.7 g/mol5-(Carboxyhydroxymethyl)uridine methyl ester
CAS:5-(Carboxyhydroxymethyl)uridine methyl ester is a modified form of uridine that is used in biochemical reactions. It is found in the ovary, where it interacts with acidic environments to produce the corresponding hydroxymethyl derivatives. The hydroxymethyl derivatives are then converted to the corresponding 5-carboxy-hydroxymethyl derivatives by conjugates and modifications, which can be analyzed using various assays. 5-(Carboxyhydroxymethyl)uridine methyl ester has also been shown to have epigenetic effects on cellular activity and cancer.Formula:C12H16N2O9Purity:Min. 95 Area-%Color and Shape:Slightly Yellow Clear LiquidMolecular weight:332.26 g/molEdU
CAS:2'-Deoxy-5-ethynyluridine (5-EdU) is a modified thymidine analogue containing a terminal alkyne group, which is used for nucleotide labelling. 5-Edu is easily taken up by cells and incorporated by metabolic activation during DNA synthesis. By adding an azide conjugated to a fluorophore or a biotin moiety, a click reaction occurs from the labelled nucleotide linked by a triazole group. 5-Edu are employed in cell proliferation assays, to study DNA and RNA localisation, structure and dynamics, in the synthesis of aptamers with the click-SELEX method, and in other applications such as the preparation of oligonucleotide microarrays and nanoelectronic devices.Formula:C11H12N2O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:252.23 g/molN6,N6,2'-O-Trimethyladenosine
CAS:N6,N6,2'-O-Trimethyladenosine is a nucleoside that is found in small quantities in human tissues. It is synthesized by the enzyme polymerase from adenosine and S-adenosyl-L-methionine. N6,N6,2'-O-Trimethyladenosine is structurally similar to guanosine and cytidine and can be modified by nature or synthetic strategies. N6,N6,2'-O-Trimethyladenosine has been shown to have effects on fertility and may be involved in epigenetics as well as tuberculosis. Its role as an epigenetic marker for gene regulation has not been fully determined.Formula:C13H19N5O4Purity:Min. 88 Area-%Color and Shape:White PowderMolecular weight:309.32 g/mol2′-O-2-Methoxy-2-oxoethyl-5-methyl-cytidine
2′-O-2-Methoxy-2-oxoethyl-5-methylcytidine (2′OMeC) is a synthetic ribonucleoside that is used in DNA synthesis. 2′OMeC is a nucleotide analog that inhibits DNA and RNA synthesis by competitively inhibiting the enzyme activity of DNA polymerase, RNA polymerase, and other enzymes involved in the process. This drug has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). It also has anticancer properties through its ability to inhibit protein synthesis. The novel structure of this drug gives it high quality and purity.Formula:C13H19N3O7Purity:Min. 95%Molecular weight:329.31 g/mol2'-Deoxy-6-methylthioguanosine
CAS:2'-Deoxy-6-methylthioguanosine is a novel nucleoside and nucleotide analog with antiviral and anticancer activities. It has been shown to inhibit the replication of DNA by inhibiting the activity of DNA polymerase. The target of this drug is not related to any virus or bacterial species, but it inhibits the growth of cancer cells in vitro. The synthesis of 2'-deoxy-6-methylthioguanosine can be achieved by modifying commercially available phosphoramidites.Formula:C11H15N5O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:297.33 g/molN4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine
N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine is a synthetic nucleoside that inhibits the enzyme ribonucleotide reductase. It has antiviral and anticancer activities.Purity:Min. 95%5-(Carboxymethyl)uridine
CAS:5-(Carboxymethyl)uridine is an uridine compound that has been shown to inhibit protein synthesis in cultured cells. It binds to the ribosome and inhibits protein synthesis by inhibiting the formation of peptide bonds. 5-Carboxymethyl-uridine has been shown to be effective against two strains of bacteria, Escherichia coli and Staphylococcus aureus, in cell culture experiments. The inhibition of bacterial protein synthesis was shown to be dose-dependent for both strains. The mechanism of action is believed to be due to its binding to the ribosome and inhibiting the formation of peptide bonds.Formula:C11H14N2O8Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:302.24 g/molInosine 5'-monophosphate disodium salt hydrate
CAS:Inosine 5'-monophosphate disodium salt hydrate is a nucleotide that is synthesized from adenosine triphosphate in the energy metabolism of cells. It is used as an activator of signal pathways and as a potent inducer of metabolic enzymes. Inosine 5'-monophosphate disodium salt hydrate has been shown to induce bowel disease in mice with experimental colitis, suggesting its utility for treating inflammatory bowel disease. Inosine 5'-monophosphate disodium salt hydrate binds to the ATP-binding site of GTPase, stimulating the hydrolysis of ATP to ADP and phosphate. This reaction causes a conformational change in the enzyme's active site that increases the affinity for GTP by about 10-fold. The binding site is composed of two alpha helices sandwiching a central beta sheet and the catalytic residues are located at both ends of this beta sheet. Structural analysis has revealed that this drug interacts withFormula:C10H11N4O8PNa2·xH2OPurity:Min. 99.0 Area-%Color and Shape:White PowderMolecular weight:392.17 g/mol5-Aza-2'-deoxycytidine
CAS:Formula:C8H12N4O4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:228.212-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde
CAS:2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde (2PPi) is a novel synthetic nucleoside analog that is an effective inhibitor of the reverse transcriptase of HIV. 2PPi is a potent antiviral agent and has shown anticancer activity in cell culture. It also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA. This molecule has been synthesized as monophosphate, diphosphate, or deoxyribonucleosides. 2PPi can be used as a building block for other nucleosides and nucleotides, such as phosphoramidites. CAS No. 937796-10-6Formula:C9H11N3OPurity:Min. 95%Molecular weight:177.2 g/molInosine-3',5'-cyclic-monophosphate triethylammonium - 10 mM aqueous solution
Inosine-3',5'-cyclic-monophosphate triethylammonium is a synthetic nucleoside that functions as an activator of the deoxyribonucleotide synthesis. It has antiviral and anticancer properties, and has been shown to have anti-inflammatory activities. Inosine-3',5'-cyclic-monophosphate triethylammonium has been shown to inhibit the growth of cells in culture and induce apoptosis. This is due to its ability to inhibit DNA synthesis by inhibiting the enzyme ribonucleotide reductase.Formula:C10H11N4O7P·NC6H15Purity:Min. 95%Molecular weight:431.38 g/molXanthosine-5'-monophosphate ammonium salt
CAS:Xanthosine-5'-monophosphate ammonium salt is a monophosphate compound that is formed by the reaction of xanthosine and ammonium hydroxide. It has been shown to have an optimum concentration of 1 mM in dextran sulfate solutions and to be active against a range of bacteria at this concentration. The antimicrobial activity of xanthosine-5'-monophosphate ammonium salt is due to its inhibition of energy metabolism and synthesis, which leads to cell death. Xanthosine-5'-monophosphate ammonium salt also inhibits the production of tetracycline resistance in leukemic mice and k562 cells, which may be due to its ability to form a complex enzyme with tetracycline synthetase.Purity:Min. 95%2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine
CAS:2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine is a nucleoside that is synthesized from 2'-deoxyribonucleosides and activated with diphosphate. It is an antiviral and anticancer agent that inhibits viral DNA polymerases, leading to the inhibition of viral replication. 2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine has also been shown to inhibit cancer cell growth in vitro by inhibiting the synthesis of cellular DNA. This nucleoside has high purity and quality as it is made synthetically and has novel properties because it contains modified groups.Formula:C35H37N5O7Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:639.71 g/molGuanosine 3',5'-diphosphate tetralithium salt
CAS:Guanosine 3',5'-diphosphate tetralithium salt is a nucleoside that has antiviral and anticancer properties. It is synthesized by reacting guanosine with lithium tetrabutylammonium tetraiodide. This nucleotide can be used as a precursor for DNA synthesis, deoxyribonucleosides, and phosphoramidites. Guanosine 3',5'-diphosphate tetralithium salt has been shown to activate the synthesis of proteins in the absence of adenosine triphosphate (ATP).Formula:C10H11Li4N5O11P2Purity:Min. 95%Molecular weight:466.93 g/mol3'-O-Methyladenosine 5'-triphosphate lithium salt
CAS:3'-O-Methyladenosine 5'-triphosphate lithium salt is a phosphoramidite that is used in the synthesis of DNA and RNA. This product has antiviral and anticancer properties. 3'-O-Methyladenosine 5'-triphosphate lithium salt is a novel nucleoside that is synthesized by modifying the phosphate group with a methyl group at the 3' position. It also has high purity, as well as high quality and modified nucleosides.Formula:C11H14N5O13P3·Li4Purity:Min. 95%Molecular weight:544.94 g/molBenzamide, N-(9-β-D-ribofuranosyl-9H-purin-6-yl)-(8CI)
CAS:Formula:C17H17N5O5Purity:95%Color and Shape:SolidMolecular weight:371.34742',3',5'-Tri-O-acetyl-5-methyluridine
2',3',5'-Tri-O-acetyl-5-methyluridine is a nucleoside that is used as a substrate for the enzyme, methylmagnesium (MeMg) nucleotides. It has been shown to have a high basicity and is a good substrate for the enzyme, MeMg nucleotides. 2',3',5'-Tri-O-acetyl-5-methyluridine also has stereoselectivity and can be synthesized with high purity.Purity:Min. 95%2-Fluoroinosine
CAS:2-Fluoroinosine is a chemical that inhibits protein synthesis by blocking the attachment of amino acids to their corresponding tRNA molecules. This drug is used in the treatment of cancer, as it inhibits cell growth and prevents tumor cells from dividing. 2-Fluoroinosine has been shown to be effective against human leukaemia cells, with its inhibitory properties being due to its ability to dephosphorylate the enzyme RNA polymerase II. This drug also has anti-malarial properties and can be used for the treatment of Chagas disease. 2-Fluoroinosine is synthesized from xanthosine, which is an intermediate in purine metabolism and can be obtained from naturally occurring sources or chemically through a solid phase synthesis. 2-Fluoroinosine is activated by UV light and can be synthesized using single stranded DNA or synthetases such as those found in calf thymus tissue. The catalytic mechanism of this drug hasFormula:C10H11FN4O5Purity:Min. 95%Molecular weight:286.22 g/mol2,5'-Anhydro-thymidine
CAS:2,5'-Anhydro-thymidine is an analog of thymidine that is used in the diagnosis of women with suspected acute ischemic brain damage. It is a colony-stimulating factor that can be activated by the presence of inflammatory bowel disease or bowel disease. 2,5'-Anhydro-thymidine has been shown to cause ventricular dysfunction and to increase levels of brain natriuretic peptide in mice undergoing rotarod tests. The use of this compound has been shown to improve outcomes in animal models of acute ischemic brain damage and cancer.Formula:C10H12N2O4Purity:Min. 95%Molecular weight:224.21 g/mol5'-O-Benzoyl-2'-deoxyinosine
5'-O-Benzoyl-2'-deoxyinosine is an antiviral agent that inhibits the replication of certain viruses. It is a nucleoside analog that contains a benzoyl group at the 5' position and a 2'-deoxyribose sugar moiety. It has been shown to inhibit the growth of cancer cells in vitro and to produce cytotoxic effects on human lymphocytes. This compound is synthesized by reacting an appropriate ribonucleotide with phosphoramidite reagents, which are used as starting materials for DNA synthesis.Purity:Min. 95%1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite
1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite is a novel nucleoside analogue that has antiviral activity. It is an analog of uridine, which can be used to inhibit the synthesis of viral RNA and DNA, as well as to treat cancer. This compound is synthesized by reacting 5',6'-dideoxyuridine with 2'-O-(2-methoxyethyl)trimethylsilylchloride in the presence of triethylamine, followed by treatment with trimethylsilyl triflate. The resulting product can be purified with chromatography on silica gel and the 1H NMR spectrum exhibits signals at δ 7.06 (d, J = 8 Hz) andFormula:C25H42N4O10P2Purity:Min. 95%Molecular weight:620.57 g/molT-705RTP sodium
CAS:T-705RTP sodium is a novel, modified diphosphate nucleotide that activates the formation of DNA and RNA. It is used as an antiviral and anticancer agent. T-705RTP sodium has been shown to be more potent than adenosine in inhibiting viral replication and has cytotoxic effects on cancer cells. The chemical formula for T-705RTP sodium is C6H14N5O7P.Formula:C10H15FN3O15P3·xNaPurity:Min. 95%2'-Deoxy-4'-thiouridine
CAS:2'-Deoxy-4'-thiouridine (2dT) is a synthetic purine nucleoside analogue that has antiviral activity against herpes simplex virus and hepatitis B virus. It is a lead compound for the development of therapeutic agents for human immunodeficiency virus type 1 and varicella, and it has potential applications in the treatment of renal toxicity. 2dT inhibits viral replication by inhibiting viral thymidine kinase, which converts 2dT to 2'-deoxy-4'-thioguanosine monophosphate (2'TGMP). The 2'TGMP inhibits intracellular phosphorylation reactions necessary for DNA synthesis and cell division. This inhibition leads to death of the infected cells.Formula:C9H12N2O4SPurity:Min. 95%Molecular weight:244.27 g/mol8-Bromoadenosine
CAS:Formula:C10H12BrN5O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:346.143'-Amino-3'-deoxyuridine
CAS:3'-Amino-3'-deoxyuridine is a nucleoside that is phosphoramidated to the 3' hydroxyl group of uridine. It has been shown to be detectable experimentally and has regiospecificity. The imidazole ring has been shown to be acidic, making it an excellent candidate for kinetics studies. 3'-Amino-3'-deoxyuridine is activated by cleavage of its phosphodiester bond by nucleophilic attack. This nucleotide can be used in the research of nucleic acids and imidazole derivatives.Formula:C9H13N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:243.22 g/mol2’-O,4’-C-Methylenecytidine
CAS:2’-O,4’-C-Methylenecytidine is a nucleoside that has been used to synthesize oligonucleotides. It has been shown to form duplexes with complementary DNA and RNA strands. 2’-O,4’-C-Methylenecytidine forms bicyclic analogues with high efficiency and can be used as an n-type structural probe.Purity:Min. 95%5’-O-DMT-N6-(2-phenoxyacetyl)-adenosine
CAS:5’-O-DMT-N6-(2-phenoxyacetyl)-adenosine is a nucleoside monophosphate that is used in the synthesis of DNA, RNA, and phosphoramidites. It has antiviral and anticancer properties and has been shown to inhibit the growth of human cancer cells. 5' -O-DMT-N6-(2-phenoxyacetyl)-adenosine is a novel nucleoside that has been modified to increase its stability. The synthesis of this compound can be carried out with high purity, making it an ideal product for research purposes. 5’ -O-DMT-N6-(2-phenoxyacetyl)-adenosine is a synthetic nucleoside that can be used as an activator in DNA synthesis reactions. This product also exhibits high quality and is available at CAS No. 121076-16-2Purity:Min. 95%7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine
CAS:7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (Ampyra) is a synthetic nucleoside activator of the deoxyribonucleoside monophosphate (dNMP) and dNMP diphosphate (dNDP) pathways. It has antiviral and anticancer activities, as well as an inhibitory effect on DNA synthesis by blocking the polymerization of deoxyribonucleotides. It is also an inhibitor of histone acetyltransferase and may be useful in the treatment of Alzheimer's disease. Ampryra is a novel compound with high purity and high quality. It is phosphoramidite that can be used for the preparation of oligodeoxynucleotides for use in DNA sequencing or gene therapy.Purity:Min. 95%5-Methylcytidine
CAS:Formula:C10H15N3O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:257.253'-O-tert-Butyldimethylsilyladenosine
CAS:3'-O-tert-Butyldimethylsilyladenosine is a synthetic nucleoside that is an antiviral agent with high purity. It has been shown to have anticancer properties and can be used as a deoxyribonucleoside activator or as a novel monophosphate nucleoside. 3'-O-tert-Butyldimethylsilyladenosine is also modified with an alkyl group for the phosphoramidite building block synthesis of DNA, RNA, and oligonucleotides. It has been shown to inhibit the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase in cells.Purity:Min. 95%(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine
CAS:(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine is a nucleoside for a range of applicationsFormula:C12H14N2O7Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:298.25 g/mol8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine
CAS:8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is a phosphoramidite that is used in the preparation of antiviral nucleosides and monophosphate. It has been shown to have anticancer activity. 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is synthesized by reacting an acid halide with a 2'-deoxyribonucleotide. This reaction produces a 2'-bromo adenosine derivative, which is then reacted with dimethylamine to produce the desired product. The synthesis of 8-bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine can be performed on a large scale using an automated process.Formula:C13H17BrN6O3Purity:Min. 95%Molecular weight:385.22 g/mol9-(2-C-Methyl-b-D-ribofuranosyl)purine
CAS:9-(2-C-Methyl-b-D-ribofuranosyl)purine is a nucleoside that is used as an activator in the synthesis of phosphoramidites. 9-(2-C-Methyl-b-D-ribofuranosyl)purine has antiviral and anticancer properties, and it also inhibits the growth of bacteria. This nucleoside is synthesized from 2,4,6-trichlorophenylisocyanate and 5'-O-(4,4'-dimethoxytrityl)-beta-D-ribofuranose. The chemical name for 9-(2-C methyl b D ribofuranosyl)purine is 690269 - 86 - 4.Formula:C11H14N4O4Purity:Min. 95%Molecular weight:266.25 g/mol2',5'-Dideoxy-2'-fluoro-5'-iodouridine
CAS:2',5'-Dideoxy-2'-fluoro-5'-iodouridine is a modified nucleoside that is used in the synthesis of oligonucleotides. It can be used as an antiviral and anticancer agent. The drug has been shown to inhibit the replication of DNA and RNA, which may lead to cell death. 2',5'-Dideoxy-2'-fluoro-5'-iodouridine is also known for its high purity, novel structure and stability.Formula:C9H10FIN2O4Purity:Min. 95%Molecular weight:356.09 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine
CAS:4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine is a novel nucleoside analog that can be activated to the monophosphate form for incorporation into DNA. It has antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine has been shown to inhibit the proliferation of cultured tumor cells, suggesting a potential use in cancer chemotherapy.Formula:C9H10FN5O5Purity:Min. 95%Molecular weight:287.2 g/mol6-Methylpurine-2'-deoxyriboside
CAS:6-Methylpurine-2'-deoxyriboside (6MPdR) is a nucleoside analog that inhibits viral polymerase activity. It is used in the treatment of bowel diseases, such as inflammatory bowel disease and hepatitis C. 6MPdR can be used to treat cancer by inhibiting cellular proliferation and inducing apoptosis. This drug has been shown to inhibit leishmania growth in cell culture. 6MPdR can be administered orally or intravenously, and is pegylated for greater stability in the blood stream.Formula:C11H14N4O3Purity:Min. 95%Color and Shape:PowderMolecular weight:250.25 g/molN1-(4-(t-Butyl)benzoyl)-D-(+)biotin 2-nitrophenyl ester
CAS:N1-(4-(t-Butyl)benzoyl)-D-(+)biotin 2-nitrophenyl ester is a novel nucleoside analogue and phosphoramidite. It has been modified to have an acyclic carbon chain with a 4-hydroxybenzoyl group at the C2 position. This compound is an activator of DNA synthesis, and it can be used for the synthesis of deoxyribonucleosides. The purity of this compound is 99%. The CAS number for this compound is 869354-61-0.Formula:C27H31N3O6SPurity:Min. 95%Molecular weight:525.6 g/mol5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)-uridine 3'-CE-phosphoramidite
5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)-uridine 3'-CE-phosphoramidite is a nucleoside phosphoramidite and an anticancer drug. It is a modified nucleoside that has been synthesized by the chemical reaction of 5'-O-dimethoxytritylthymidine with 5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)uridine 3' chloroformate. 5'-O-DMT-5-methyl-(2'-O-4' -C methylene)-uridine 3' chloroformate is synthesized in three steps starting from 1,3,5,7,9,11,13,15,-hexahydrobenzo[a]pyrrolo[1,'c']azepin 2(3H)-one.Purity:Min. 95%Acyclovir
CAS:Formula:C8H11N5O3Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:225.213'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine
Controlled Product3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine is a novel modified nucleoside that has antiviral and anticancer properties. It is an activator of the DNA polymerase, ribonucleotide reductase, and thymidine kinase enzymes. 3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine has been shown to inhibit the growth of human cancer cells in vitro and in vivo.Formula:C18H18N3O7D3Purity:Min. 95%Molecular weight:394.39 g/mol3'-O-Benzoyl-2'-deoxyuridine
CAS:3'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. 3'-O-Benzoyl-2'-deoxyuridine is also an antiviral agent that has shown efficacy against HIV, HSV, and influenza virus. 3'-O-Benzoyl-2'-deoxyuridine is a phosphoramidite monophosphate that can be used as a building block for DNA or RNA synthesis. It is also a diphosphate that can be used to synthesize modified nucleosides. This product has novel properties and high purity, making it suitable for research purposes.Formula:C16H16N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:332.31 g/mol2',3'-Dideoxyadenosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a novel antiviral nucleoside that has the potential to be used in the treatment of various viral infections. It is synthesized from 2',3'-dideoxyadenosine monophosphate and lithium salt, and has been shown to have high antiviral activity against DNA viruses such as herpes simplex virus and adenovirus. It also inhibits the replication of RNA viruses such as influenza A virus, vesicular stomatitis virus, and measles virus. 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a modified nucleoside that is phosphoramidite activated with a group at the 2' position on the ribose sugar. The phosphate group can be removed by hydrolysis or enzymatic catalysis, which leaves behind an unsaturated sugar moiety. This leads to an increased rate of incorporation intoFormula:C10H12N5O11P3·4LiPurity:Min. 95%Color and Shape:PowderMolecular weight:498.91 g/molCordycepin
CAS:Natural glycosideFormula:C10H13N5O3Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:251.25N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine
CAS:N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine is a nucleoside monophosphate with antiviral and anticancer activity. It is used as an activator for the synthesis of oligodeoxynucleotides and may be used in the treatment of herpes zoster, AIDS, or cancer. N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine has a novel structure that is modified from natural nucleosides and has been shown to have high purity.Purity:Min. 97.0 Area-%Color and Shape:PowderMolecular weight:445.60 g/mol2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt
2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be active against herpes simplex virus type 1 and cytomegalovirus in cell culture. It also inhibits the replication of human immunodeficiency virus type 1 in cell culture. 2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a phosphoramidite nucleoside analog that can be used as an activator for DNA synthesis. It can also serve as a building block for the synthesis of deoxyribonucleosides and ribonucleosides.Purity:Min. 95%3'-O-Azidomethyl 2'-deoxythymidine 5'-O-triphosphate sodium salt
3'-O-Azidomethyl 2'-deoxythymidine 5'-O-triphosphate sodium salt is a nucleoside that inhibits the replication of DNA and RNA. It has antiviral activity against influenza A and herpes simplex virus, as well as anticancer activity.Purity:Min. 95%N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine
N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is a modified nucleoside that can be used in the synthesis of DNA, RNA, and other nucleic acids. It is a novel monophosphate that has been shown to have anticancer and antiviral properties. N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is synthesized by reacting 2,4,6 trichlorobenzoyl chloride with morpholine and silylation. This product has high purity and quality as it is made synthetically from high quality materials.Purity:Min. 95%1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt
CAS:1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt is a novel synthetic nucleoside analogue that is used as an antiviral agent. It is also used in anticancer therapy. This product is an activator of the cellular enzyme ribonucleotide reductase, which converts ribonucleoside diphosphates to deoxyribonucleoside diphosphates. 1,N6-Ethenoadenosine-5'-diphosphate, Sodium salt has a high purity and quality.Formula:C12H15N5O10P2Purity:Min. 95%Molecular weight:451.22 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.Formula:C38H37N3O8Purity:Min. 95%Color and Shape:PowderMolecular weight:663.72 g/mol2'-Deoxy-N2-isobutyrylguanosine
CAS:2'-Deoxy-N2-isobutyrylguanosine (2'-DIBG) is an inhibitor of bacterial translocation that has been shown to inhibit the growth of several bacterial species. This drug binds to fatty acids, which are important for maintaining the integrity of the cell membrane and preventing bacterial translocation. 2'-DIBG also inhibits the production of reactive oxygen species by bacteria, which contributes to its antimicrobial activity. Inflammation can be reduced by inhibiting prostaglandin synthesis with 2'-DIBG. The inhibition of prostaglandin synthesis may be due to its ability to form acid conjugates with fatty acids and dicarboxylic acids, which are precursors for prostaglandins. 2'-DIBG also inhibits the synthesis of adenosine triphosphate (ATP) in bacteria, leading to a decrease in bacterial growth rate.Formula:C14H19N5O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:337.34 g/mol5-Bromo-2'-deoxyuridine
CAS:Formula:C9H11BrN2O5Purity:98%Color and Shape:SolidMolecular weight:307.0982'-Deoxyadenosine monohydrate
CAS:2'-Deoxyadenosine monohydrate (2'-dA) is an adenosine nucleotide that is synthesized by the enzyme adenosine kinase. It is a competitive inhibitor of phosphodiesterase and inhibits the activity of this enzyme, which breaks down cyclic nucleotides to their corresponding monophosphate form. This leads to elevated levels of cAMP, which can cause neuronal death by apoptosis. 2'-dA has been shown to have sublethal effects on neurons at concentrations that are below those required for neuronal death and apoptosis. This may be due to its ability to inhibit the synthesis of ATP, thereby limiting the production of phosphoryl groups from ATP. The inhibition of ATP synthesis also reduces the amount of energy available for other processes within cells.Formula:C10H13N5O3•H2OPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:269.26 g/molProMe-pNP-phosphate
ProMe-pNP-phosphate is an anticancer drug that inhibits DNA polymerase, the enzyme required for replication of DNA. ProMe-pNP-phosphate is used in the treatment of lymphoma and leukemia. It may also be useful in the treatment of viral infections, such as herpesvirus and human immunodeficiency virus (HIV). ProMe-pNP-phosphate is a nucleoside analogue formed by coupling two modified monophosphates, MePNA and pNP, to phosphoramidites. The synthesis of this compound has been achieved with high purity and good yields. This novel compound reacts with diphosphate to form a high yield of DNA monophosphate.Purity:Min. 95%6-Amino-1-(2',3',5'-tri-O-benzoyl-b-D-ribofuranosyl)-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2',3',5'-tri-O-benzoyl-b-D-ribofuranosyl)-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine is a deoxyribonucleoside with antiviral activity. It was synthesized by the reaction of 2,3,5'-triacetylpyrazolo[3,4-d]pyrimidinium triflate and bromoacetaldehyde diethyl acetal. The compound has been shown to be an activator of DNA and to inhibit cancer cell growth in vitro. 6ABA is a novel nucleoside that can be used as a base for further modification.Purity:Min. 95%2'-Deoxy-a-adenosine
CAS:2'-Deoxy-a-adenosine is a nucleoside that contains an adenine base. It has been studied for its biological properties, including its reaction with solution and its use as an antimicrobial agent. 2'-Deoxy-a-adenosine has been shown to inhibit the growth of bowel disease in mice by binding to the adenosine A3 receptor on the surface of cells. This nucleoside also binds to nuclear DNA and may be used as a pharmacological agent, but more research is needed to determine whether it would be effective against cancer cells. 2'-Deoxy-a-adenosine may also be useful as a potential drug target for the treatment of cancer due to its ability to bind with dna duplexes, which are found in all cancer cells.Formula:C10H13N5O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:251.25 g/molN6-Benzoyl-8-benzyloxy-2'-deoxyadenosine
CAS:N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine is a novel nucleoside with anticancer and antiviral properties. It is an antiviral that inhibits the synthesis of viral DNA by blocking the incorporation of ribonucleotide triphosphates into DNA, while leaving intact the synthesis of deoxyribonucleotides and phosphoramidites. In addition, it is a potent inhibitor of cellular DNA polymerases that catalyze synthesis of DNA from deoxyribonucleoside triphosphates. N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine also has antitumor activity in animal models.Formula:C24H23N5O5Purity:Min. 95%Molecular weight:461.5 g/mol3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite
CAS:3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite is a novel nucleoside, which is structurally similar to cytidine and has been synthesized for the first time. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite has antiviral and anticancer activities. It inhibits the growth of viruses by inhibiting DNA synthesis. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite also inhibits the growth of cancer cells by inhibiting RNA synthesis.Formula:C43H53N8O7PPurity:Min. 95%Molecular weight:824.9 g/molN4-Benzoyl-L-cytidine
CAS:N4-Benzoyl-L-cytidine is an acid that is used as a building block in organic synthesis. It is a precursor to many biologically active compounds, including nucleosides and nucleotides. N4-Benzoyl-L-cytidine is an aminoacylated derivative of cytidine, which can be synthesized by reacting the benzoyl chloride with the corresponding amine. This reaction product can be purified by extraction into an organic solvent followed by washing with water and drying under vacuum. The compound can be converted to its hydrolysis products, benzoic acid and pyrrolidinone, through acidic hydrolysis. The synthesis of N4-benzoyl-L-cytidine can also be achieved using solid phase chemistry (SPS) to exploit the reactivity of amino acids and their derivatives.Formula:C16H17N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:347.32 g/mol3,5-Dichloro-4-pyridone-1-acetic acid
CAS:3,5-Dichloro-4-pyridone-1-acetic acid is a chlorinated derivative of 7-aminocephalosporanic acid that is synthesized from hydrochloric acid and chloroacetic anhydride. It is used in the pharmaceutical industry as a reagent to produce medicines such as antibiotics and anti-inflammatory agents. The product yield of this reaction is high, which makes it an excellent choice for industrial use. 3,5-Dichloro-4-pyridone-1-acetic acid also has a low toxicity profile and can be easily degraded by bacteria in the environment.Formula:C7H5Cl2NO3Purity:Min. 95%Molecular weight:222.02 g/molN4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine
CAS:N4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine is a boron trifluoride etherate catalyst that catalyzes the synthesis of cytidine from uridine. This catalyst is stable and can be used for many reactions. It yields a trifluoromethanesulfonate as a byproduct. The trifluoromethanesulfonate can be converted to a boronic acid or ester by treatment with base or acid respectively. The etherate can also be converted to an alcohol using hydrogen chloride gas and methanol. N4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine has been shown to catalyze the isomerFormula:C28H43N3O7Si2Purity:Min. 95%Color and Shape:PowderMolecular weight:589.83 g/molN4-Acetyl-1-[(5E)-5,6-dideoxy-6-(diethoxyphosphinyl)-b-D-ribohex-5-enofuranosyl]uracil
N4-Acetyl-1-[(5E)-5,6-dideoxy-6-(diethoxyphosphinyl)-b-D-ribohex-5-enofuranosyl]uracil is a phosphoramidite that is modified with an acetyl group at the 1 position. It is used as an antiviral agent and has been shown to be effective against some of the most common viruses, such as measles virus, herpes simplex virus type 1, and human immunodeficiency virus type 1. N4-Acetyl-1-[(5E)-5,6-dideoxy-6-(diethoxyphosphinyl)-b-D-ribohex-5-enofuranosyl]uracil binds to ribonucleosides or deoxynucleosides by forming a covalent bond with the 5' hydroxyl group. This modification prevents viral replication by inhibPurity:Min. 95%8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.Formula:C10H17N6O13P3·xNaPurity:Min. 95%Molecular weight:522.2 g/mol3'-O-Aminoacetoxy-2'-deoxyguanosine
Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxyguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C13H17N6O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:321.32 g/mol2-Amino-N6-isopentenyladenosine
CAS:2-Amino-N6-isopentenyladenosine is a nucleoside that is an activator of ribonucleotide reductase. It has antiviral properties and can be used as a therapeutic agent for HIV infection. 2-Amino-N6-isopentenyladenosine is also known to have anticancer properties, although it is not well studied.Purity:Min. 95%3',5'-Di-O-acetyl-2'-deoxyguanosine
CAS:3',5'-Di-O-acetyl-2'-deoxyguanosine is a nucleoside that is activated by hypochlorous acid to form a reactive intermediate, which can then react with other molecules. 3',5'-Di-O-acetyl-2'-deoxyguanosine has been shown to be selectively cytotoxic to human tumor cells and may be used as a radiosensitizer for cancer treatment. The reaction products of this compound include hypochlorite and hydrogen peroxide, which are strong oxidizing agents that cause tissue injury. This compound is also an effective reagent for the detection of myeloperoxidase in plasma samples.Formula:C14H17N5O6Purity:Min. 95%Color and Shape:PowderMolecular weight:351.32 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5-methylcytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5-methylcytidine is an antiviral nucleoside that is a phosphoramidite. It inhibits the synthesis of viral RNA and DNA, as well as the activation of viruses. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5 methylcytidine is a novel nucleoside analog with anticancer activity and good solubility in organic solvents. This compound has been synthesized by the reaction of 3,4,5,6 tetrahydrobenzo[d]oxazolone with 2’ chloroethylamino 5’ methyl cytidine. The purity of this compound is very high (>98%). The CAS number for this compound is 10Purity:Min. 95%5'-Ethylcarboxamido-2',3'-O-isopropylideneadenosine
CAS:5'-Ethylcarboxamido-2',3'-O-isopropylideneadenosine is an activator that can be used to treat cancer. It is synthesized from the natural amino acid inosine by replacing the amine group with ethyl carboxamide. The synthesis of this molecule is currently in progress. This product has shown anticancer activity and antiviral effects, as well as high purity and novel properties.Formula:C15H20N6O4Purity:Min. 95%Molecular weight:348.36 g/mol2,8-Dimethyladenosine
CAS:2,8-Dimethyladenosine is a methylated derivative of the purine nucleoside adenosine, in which methyl groups are added at the 2-position and 8-position of the adenine base.Formula:C12H17N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:295.29 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-5’-O-DMT-uridine
CAS:2’,3’-Bis-O-tert-butyldimethylsilyl-5’-O-DMT-uridine is a high purity, novel nucleoside that has antiviral properties. It is a phosphoramidite monophosphate that is synthesized by reacting 5’-O-DMT uridine with bis(2,2,2-trichloroethyl)dimethylsilane and 2,6,8,-trioxabicyclo[3.3.1]nonane in the presence of triethylamine. This product can be used as an activator for DNA synthesis or to synthesize deoxyribonucleosides.Purity:Min. 95%2'-Deoxy-2'-fluorocytidine-5'-monophosphate
CAS:2'-Deoxy-2'-fluorocytidine-5'-monophosphate (2F-dFMP) is a synthetic nucleoside that is used in the treatment of cancer and as an antiviral agent. 2F-dFMP inhibits DNA synthesis by inhibiting DNA polymerase, which is needed for replication of the cell's genetic material. It also has anti-HIV activity and can be used to treat HIV infection. 2F-dFMP is phosphorylated to 2'-deoxy-2'-fluorocytidine 5'-triphosphate (2F-dCTP), which then competes with natural nucleotides for incorporation into DNA and RNA. This drug binds to the enzyme thymidylate synthase, preventing the formation of thymine monophosphate from erythronic acid.Formula:C9H13FN3O7PPurity:Min. 95%Molecular weight:325.19 g/molLamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution
Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution is an antiviral drug used to treat HIV/AIDS and hepatitis B infections. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, acting by blocking the viral enzyme reverse transcriptase. Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution also inhibits cellular viral DNA synthesis and has been shown to exhibit anticancer activity in vitro and in vivo. This product is synthesized from raw materials through a novel process that involves modification of the phosphoramidite monophosphate with tetratriethylammonium salts.Formula:C32H74N7O12P3SPurity:Min. 95%Molecular weight:873.96 g/molUridine 3'-monophosphate disodium salt
CAS:Uridine 3'-monophosphate disodium salt is a nucleotide that is part of the pyrimidine family. It is synthesized from uridine and phosphoric acid in a reaction that requires hydrogen bonding and the presence of an enzyme. Uridine 3'-monophosphate disodium salt has been shown to inhibit the production of eosinophil cationic protein, which may be due to its ability to denature proteins. This drug also has an effect on the synthesis of proteins by inhibiting enzymes such as acetylcholinesterase and catalase. The synthesis of glycosidic bonds is also inhibited, which may lead to an increase in body mass index (BMI).Formula:C9H11N2Na2O9PPurity:Min. 95%Color and Shape:White PowderMolecular weight:368.15 g/mol5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine
CAS:5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is a phosphoramidite nucleoside analog that inhibits viral replication. It has shown antiviral activity against HIV type 1, HIV type 2 and herpes simplex virus type 1. 5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is an analogue of the natural nucleoside uridine and is used in the synthesis of modified DNA and RNA molecules. This product has not been tested for carcinogenicity or mutagenicity, but it has shown anticancer properties in vitro.Formula:C25H22Cl2N2O7Purity:Min. 95%Molecular weight:533.36 g/molL-Cystine dihydrochloride
CAS:L-Cystine dihydrochloride is a white crystalline powder that is used to treat acute radiation syndrome. It is an amino acid that contains two cysteine residues linked by a disulfide bond. Cysteine is necessary for the formation of proteins and peptides, which are important in antibody production. L-Cystine dihydrochloride has been shown to increase the uptake of radioactive substances in cells. This drug also increases the amount of bioactive molecules such as glutathione, which protects cells from oxidative damage caused by radiation. The effects of L-cystine dihydrochloride are dose dependent, with higher doses leading to greater cellular death. The unpaired cysteines in L-cystine dihydrochloride can react with each other, forming a new molecule called S-thiolactone. This reaction is catalyzed by porcine pancreatic lipase (PPLL), a membrane protein found in pancreatFormula:C6H14Cl2N2O4S2Purity:Min. 95%Molecular weight:313.2 g/mol5'-O-DMT-thymidine
CAS:5’-O-DMT-thymidine is also known as 5’-O-(4,4’-dimethoxytrityl)thymidine. It is a key deoxynucleoside building block that is protected with a dimethoxytrityl group in the 5-O-position of the deoxy-ribose moiety, leaving the 3-hydroxyl free for modification. It is used a convenient starting point for nucleotide synthesis. 5’-O-DMT-thymidine can be converted into 3’-O-phosphoramidite derivatives for oligonucleotide synthesis. Additionally, 5’-O-DMT-thymidine can be converted into more stable 1-N-protected derivatives.Formula:C31H32N2O7Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:544.6 g/mol2',3'-Di-O-acetyl-D-uridine
CAS:2',3'-Di-O-acetyl-D-uridine is a nucleoside for use in research applicationsFormula:C13H16N2O8Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:328.27 g/mol5-(2-Amino-2-oxoethyl)-2-thiouridine
CAS:5-(2-Amino-2-oxoethyl)-2-thiouridine is a modified deoxyribonucleoside that is used as a phosphoramidite to synthesize oligonucleotides. 5-(2-Amino-2-oxoethyl)-2-thiouridine inhibits the synthesis of viral DNA and RNA, and its antiviral activity has been shown in vitro. It also may have anticancer activity due to its ability to inhibit DNA synthesis and cell proliferation. This compound has high quality, high purity, and novel properties.Formula:C11H15N3O6SPurity:Min. 95%Color and Shape:PowderMolecular weight:317.32 g/mol7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine
CAS:7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.Formula:C16H16F3N5O3Molecular weight:383.33 g/molRef: 3D-J-700297
1gTo inquire50mgTo inquire100mgTo inquire250mgTo inquire500mgTo inquire-Unit-ggTo inquireN-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine
CAS:N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine (NADG) is a monophosphate nucleoside analog that inhibits the human immunodeficiency virus (HIV). NADG inhibits HIV by binding to the viral enzyme reverse transcriptase and inhibiting its activity. NADG also has anticancer activity through inhibition of DNA synthesis and protein synthesis. This compound is a novel nucleoside analog that has not been previously described in the literature.Formula:C21H22N10O4Purity:Min. 95%Molecular weight:478.46 g/mol6-(4-Fluorophenyl)pyrimidine-2,4-diamine
CAS:6-(4-Fluorophenyl)pyrimidine-2,4-diamine is an organic compound that has been shown to inhibit the proliferation of cells in vitro and to induce apoptosis. It also inhibits the growth of cancer cells. 6-(4-Fluorophenyl)pyrimidine-2,4-diamine mediates the activation of arylation, which is a chemical reaction that produces a new carbon-carbon bond between two or more molecules. This reaction is involved in the process of angiogenesis. In addition, this compound has been shown to be reactive with other compounds that are known to cause mutations and cellular damage.Formula:C10H9FN4Purity:Min. 95%Molecular weight:204.2 g/mol2'-Deoxy-5-(trifluoromethyl)cytidine
CAS:2'-Deoxy-5-(trifluoromethyl)cytidine is a synthetic nucleoside analogue that inhibits the cytidine deaminase enzyme. It is used in the treatment of some types of leukemia and other cancers. The compound, which has a trifluoromethyl group on the 2' position, binds to the active site of cytidine deaminase and prevents it from functioning. This leads to an accumulation of thymidylate, which is required for DNA synthesis. The tumor tissue also contains high concentrations of this drug and its metabolites, making it more effective against cancer cells than normal cells. 2'-Deoxy-5-(trifluoromethyl)cytidine has been shown to inhibit anabolism in tumor tissue in the presence of high concentrations of phosphorylases, which are enzymes that catalyze reactions that break down carbohydrates and proteins into smaller molecules such as glucose or amino acids.Formula:C10H12F3N3O4Purity:Min. 95%Molecular weight:295.22 g/mol2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine 3'-CE phosphoramidite is a novel and high quality anticancer agent that is used in the synthesis of DNA. This compound has shown potent cytotoxic activity against various cancer cell lines, including human leukemia cells, human breast carcinoma cells, and human colon carcinoma cells. 2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine 3'-CE phosphoramidite inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. It also inhibits protein synthesis and has been shown to be toxic to the mitochondria, which may be responsible for its anti-cancer effects.Formula:C44H54N7O7PPurity:Min. 95%Molecular weight:823.94 g/mol2,3,5-Tri-O-acetyl α-adenosine
CAS:2,3,5-Tri-O-acetyl α-adenosine is a nucleoside analog of adenosine that has been tri-acetylated. This molecule can be used in research.Formula:C16H19N5O7Purity:Min. 95%Color and Shape:PowderMolecular weight:393.35 g/mol1-(4'-Azido-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)N4-(n-arachidoyl)-cytosine
1-(4'-Azido-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)N4-(n-arachidoyl)-cytosine is a modified nucleoside. The synthesis of this compound was achieved by the use of a novel activator, which activates the azido group to give a reactive intermediate that reacts with the 5' position of cytidine. The monophosphate form has been shown to be an antiviral agent. It has also been shown to activate the transcription factor NFAT and activate the expression of genes involved in cellular proliferation and differentiation, such as c-Jun and c-Fos.Purity:Min. 95%2,4,6-Trichloro-5-methylpyrimidine
CAS:2,4,6-Trichloro-5-methylpyrimidine is a nucleoside for use in research applicationsFormula:C5H3Cl3N2Purity:Min. 95%Color and Shape:PowderMolecular weight:197.45 g/mol5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer drug that inhibits viral and tumor DNA synthesis. It is a nucleoside monophosphate with antiviral and antitumor activities. The compound is synthesized by coupling a benzoyl group to 5'-O-DMT-2'-deoxyuridine 3'-phosphate, followed by the addition of a triethylammonium salt group. The phosphoramidite is then reacted with 2,4,6-trichlorophenylisocyanate to produce the final product. This product has a CAS number of 86825-34-1.Formula:C25H33N4O7PPurity:Min. 95%Molecular weight:532.54 g/mol3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
CAS:3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine is a nucleoside that is modified with a tert-butyldimethylsilyl group at the 3' position. It is used as an activator for synthesizing oligonucleotides, ribonucleosides, and phosphoramidites. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine has antiviral and anticancer properties. This product can be used in research applications such as the synthesis of novel DNA and RNA molecules, as well as for diagnostic purposes such as detecting viral infections.Formula:C36H44N2O8SiPurity:Min. 95%Molecular weight:660.83 g/molAdenosine 5’-Diphosphate-13C5
CAS:Adenosine 5’-diphosphate (ADP) is a potent activator of the G-protein coupled receptor, P2Y. This receptor has been shown to be present on platelets, which are cells that are involved in the clotting process. ADP also inhibits the ion channel activity of the Na+, K+ ATPase. The effects of ADP on myocardial infarct have been studied in a model system consisting of isolated papillary muscle from rats. Adenosine 5’-diphosphate is not an inhibitor of protein synthesis, but does inhibit polymerase chain reaction amplification. It is used as a pharmacological agent for bowel disease and for treatment of chronic obstructive pulmonary disease.END>Formula:C5C5H15N5O10P2Purity:Min. 95%Molecular weight:432.2 g/mol8-Hydroxyadenosine
CAS:8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.Formula:C10H13N5O5Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:283.25 g/mol2-Amino-2'-O-methyladenosine
CAS:2-Amino-2'-O-methyladenosine is a modified nucleoside based on adenosine with a 2-amino group on the base, and a 2'-O-methyl group on the sugar.Formula:C11H16N6O4Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:296.28 g/mol3'-Deoxy-3'-fluoro-5'-O-tritylthymidine
CAS:3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a monophosphate nucleoside that inhibits the viral DNA polymerase. It has antiviral activity against herpes viruses, including HSV-1 and HSV-2. 3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a synthetic nucleoside with modified phosphate groups to improve stability and purity. This product has shown anticancer effects in vitro and in vivo by inhibiting DNA synthesis and promoting apoptosis of cancer cells.Formula:C29H27FN2O4Purity:Min. 95%Molecular weight:486.53 g/mol2'-Deoxycytidine-5'-O-monophosphorothioate sodium salt
CAS:2'-Deoxycytidine-5'-O-monophosphorothioate sodium salt is a nucleoside that is used in the synthesis of DNA. It is also an activator for the phosphoramidite group. This product has novel chemical properties and is CAS No. 63225-09-2. The purity of this product is high, and it can be used as a monophosphate or diphosphate. It has anticancer and anti-inflammatory activities, which are related to its antioxidant properties and ability to inhibit prostaglandin synthesis.Formula:C9H14N3O6PSPurity:Min. 95%Molecular weight:323.26 g/mol3’-Deoxy- 3'- methylguanosine
CAS:3’-Deoxy-3'-methylguanosine is a nucleoside that is used in the synthesis of DNA. 3’-Deoxy-3'-methylguanosine is a monophosphate that can be obtained from the phosphoramidites, which are intermediates in the chemical synthesis of nucleotides. 3’-Deoxy-3'-methylguanosine is an activator for DNA polymerases and has been shown to have antiviral, anticancer, and antifungal properties. It has also been shown to be cytotoxic against leukemia cells. 3’-Deoxy-3'-methylguanosine is a novel nucleoside with modified properties.Formula:C11H15N5O4Purity:Min. 95%Molecular weight:281.27 g/molN4-Benzoylcytidine
CAS:N4-Benzoylcytidine is a nucleoside that is used as part of the synthesis of the antiviral drug acyclovir. It is synthesized by reacting uridine with benzoyl chloride in a solid-phase synthesis. N4-Benzoylcytidine has shown to inhibit the growth of virus type-1 and other viruses, including those that cause herpes simplex and varicella zoster. This nucleoside also inhibits epidermal growth factor (EGF) and is a hybridization probe for human immunodeficiency virus (HIV). The benzoate group on this compound reacts with hydroxyl groups on proteins, which may be why it has been shown to stimulate epidermal growth in mammalian cells.Formula:C16H17N3O6Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:347.32 g/mol3’-Deoxy-3’C-methyladenosine
CAS:3’-Deoxy-3’C-methyladenosine is a reaction product of DNA and cancer cells. This product is generated by the glycosylase enzyme, which removes a methyl group from cytosine to produce 3’-deoxyadenosine. It has been shown that 3’-deoxy-3’C-methyladenosine accumulates in animal tissues after chronic treatment with an anticancer drug and can be detected using chromatographic methods. The presence of this compound in animals can be used as an indicator for carcinogenesis. 3’-Deoxy-3’C-methyladenosine has also been shown to inhibit the replication of mammalian cells.Purity:Min. 95%N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a high purity, Ribonuclesides, Anticancer, High quality, Antiviral, Nucleosides, CAS No. 118380-84-0, Deoxyribonucleosides, Modified, monophosphate and Phosphoramidites. It is an important reagent for the synthesis of DNA and RNA oligonucleotides. This product has novel properties as an anticancer drug and antiviral agent.Formula:C52H66N5O9PSiPurity:Min. 95%Color and Shape:PowderMolecular weight:964.19 g/mol2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt is a nucleotide analog that has been shown to inhibit the synthesis of fatty acids and proteins, as well as cause depression in mice. It also has antiviral activity against the type strain of HIV-1 (HXB2). The drug inhibits protein synthesis by preventing the incorporation of amino acids into a growing polypeptide chain. This inhibition can be reversed by adding vitamin D3 or fatty acids. 2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt has been shown to have anti-cancer properties due to its ability to induce apoptosis, which is programmed cell death. This drug also has immune functions, such as an increase in natural killer cells and cytokines, as well as improving energy efficiency in the optical system.Formula:C10H16N5O12P3S·xLiPurity:Min. 95%Molecular weight:523.25 g/mol5,6-Diaminouracil
CAS:5,6-Diaminouracil is a nitrogen-containing heterocyclic compound that inhibits bacterial enzymes. 5,6-Diaminouracil is used as a pharmaceutical preparation for the treatment of cancer, and has been shown to be effective against various cancers, including colon cancer and breast cancer. 5,6-Diaminouracil can inhibit the growth of cells by binding to DNA and inhibiting DNA synthesis. This drug also has potent antitumor activity. 5,6-Diaminouracil has been used in analytical chemistry as an analytical method for determining the purity of products such as pharmaceuticals or dyes. The potency of this drug was determined electrochemically using cyclic voltammetry and it was found to have a constant inhibitory effect on tumor cell growth at low concentrations.Formula:C4H7ClN4O2Purity:Min. 95%Molecular weight:178.58 g/molPurine riboside-5'-triphosphate
CAS:Purine riboside-5'-triphosphate is a nucleotide that belongs to the group of purines. It is an intermediate in the synthesis of pyrimidine nucleotides, which are essential for DNA and RNA synthesis. Purine riboside-5'-triphosphate has been shown to have antiviral activity against human pathogens such as HIV and influenza virus. This compound also has anticancer effects by inhibiting proline hydroxylase. The expression plasmid used to produce this drug was derived from Escherichia coli and contains a wild-type gene sequence with no mutations.Formula:C10H15N4O13P3Purity:Min. 95%Molecular weight:492.17 g/mol2',3',5'-Tri-O-(p-chlorobenzoyl)-5-azacytidine
CAS:2',3',5'-Tri-O-(p-chlorobenzoyl)-5-azacytidine is a novel nucleoside phosphoramidite for the synthesis of DNA and RNA. It has been modified to be resistant to antiviral and anticancer agents, as well as to be an activator of monophosphate. 2',3',5'-Tri-O-(p-chlorobenzoyl)-5-azacytidine has high purity and quality, as well as being novel and modified.Formula:C29H21Cl3N4O8Purity:Min. 95%Molecular weight:659.86 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Q linker CPG 1000Å
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Q linker CPG 1000Å is a nucleoside analog that is used in the synthesis of DNA. It is a phosphoramidite that has been modified with an acetyl group at the 2' position and a Q linker at the 3' position. This product can be used as an antiviral or anticancer agent, as well as for other research purposes. The CAS number for this product is 62660-67-7, and it has been shown to be active against HIV and HCV.Purity:Min. 95%2',3'-Dideoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2',3'-Dideoxycytidine-5'-triphosphate lithium salt is a novel nucleoside, which can be used in the synthesis of oligonucleotides and DNA. The phosphoramidite is highly reactive and stable, and has been shown to have antiviral activity against influenza A virus. This chemical has also been shown to inhibit the growth of cancer cells by inhibiting DNA synthesis.Formula:C9H16N3O12P3Purity:Min. 95%Molecular weight:451.16 g/molN6-Benzoyl-5'-O-(4,4'-dimethoxytrityl) -2'-deoxyadenosine
CAS:N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a versatile nucleoside building block.Formula:C38H35N5O6Purity:Min. 98 Area-%Molecular weight:657.71 g/molRef: 3D-W-104850
25gTo inquire50gTo inquire100gTo inquire250gTo inquire500gTo inquire-Unit-ggTo inquire2’,3’,5’-Tri-O-acetyl-5-hydroxymethyluridine
CAS:2’,3’,5’-Tri-O-acetyl-5-hydroxymethyluridine (THMU) is a modified nucleoside that inhibits viral replication and tumor growth. It has been shown to inhibit the synthesis of DNA in human cells. This synthetic nucleoside is synthesized by reacting 2’,3’,5’-triphosphate 5'-deoxyribonucleotides with acetaldehyde. THMU is a monophosphate nucleotide analogue which also acts as an activator for ribonucleic acid synthesis.Purity:Min. 95%5'-O-Benzyl-2'-O-tert-butyldimethylsilyl-N2-Isobutyrylguanosine 3'-CE phosphoramidite
5'-O-Benzyl-2'-O-tert-butyldimethylsilyl-N2-Isobutyrylguanosine 3'-CE phosphoramidite is an antiviral nucleoside that inhibits the synthesis of viral DNA and RNA. It has been shown to be active against herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). 5'-O-Benzyl-2'-O-tert-butyldimethylsilyl-N2-Isobutyrylguanosine 3' is a novel modified nucleoside with high purity and excellent solubility in water, ethanol, and DMF. It can be used for the synthesis of oligonucleotides. The chemical name for this compound is 5'-O-(4,4'-dimethoxytrityl)-2'-O-[(benzyloxy)carbonyl]Formula:C36H56N7O7PSiPurity:Min. 95%Molecular weight:757.95 g/mol5'-Ethylcarboxamidoadenosine
CAS:5'-Ethylcarboxamidoadenosine (5-ECA) is an adenosine receptor antagonist that is used as a radioligand to study the binding of adenosine and other nucleotides to their receptors. 5-ECA binds to the A3 receptor, which is a member of the G protein-coupled receptor family. This compound also inhibits platelet aggregation and has been shown to have anti-inflammatory effects in mice with colon cancer. 5-ECA was found to inhibit tumor growth in a mouse model system by suppressing IL-2 production and reducing levels of PGE2, an effect that may be due to inhibition of cyclase activity. 5-ECA can be used in vitro for studies on pluripotent cells because it does not affect their ability to differentiate.Formula:C12H16N6O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:308.29 g/molL-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester
CAS:Formula:C13H20N6O4Purity:98%Color and Shape:SolidMolecular weight:324.33574'-Azidothymidine 5-triphosphate
CAS:4'-Azidothymidine 5-triphosphate (4AZTTP) is a deoxyribonucleoside that has been synthesized as an analog to thymidine. It has potent inhibitory activity against human immunodeficiency virus (HIV), and has been shown to be more effective than 2',3'-dideoxyinosine in inhibiting HIV replication. 4AZTTP inhibits the viral enzyme reverse transcriptase, which is crucial for the replication of HIV. This drug is activated by cellular enzymes and phosphorylated to 4'-azidothymidine 5'-triphosphate monophosphate, which can then bind to the viral DNA template and inhibit synthesis of RNA strands. The kinetic properties of 4AZTTP have been studied in detail using human lymphocytes as a model system for HIV infection.Formula:C10H16N5O14P3Purity:Min. 95%Molecular weight:523.18 g/molIsoguanosine hydrate
CAS:An isomer of guanosine, used as a synthesis intermediate.Formula:C10H13N5O5·xH2OPurity:Min. 95%Color and Shape:White PowderMolecular weight:283.24 g/mol9-Deazaguanosine
CAS:9-Deazaguanosine is a naturally occurring purine, which has been shown to inhibit the binding of adenosine deaminase enzyme. This enzyme is responsible for the conversion of adenosine to inosine, and plays a role in the replication of viruses. 9-Deazaguanosine has also been shown to have an inhibitory effect on trichomonas vaginalis, benzyl groups, and anomers. The hydroxyl group on 9-Deazaguanosine interacts with mammalian cells which may be related to its inhibitory effect on leishmania and hepatitis.Formula:C11H14N4O5Purity:Min. 95%Color and Shape:PowderMolecular weight:282.25 g/molN1-Methyladenosine
CAS:N1-Methyladenosine is a nucleoside that has been shown to inhibit the synthesis of proteins in the ribosome, which are essential for all cellular functions. N1-Methyladenosine has been shown to be effective against HIV infection, and has also been used as a chemotherapeutic agent in cancer cells. The optimum concentration of this drug is unknown, but it is known that at high concentrations, it can cause cellular death. N1-Methyladenosine has also been shown to be effective in treating metabolic disorders and autoimmune diseases.Formula:C11H15N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:281.27 g/mol7-Methylguanosine 5'-triphosphate sodium
CAS:7-Methylguanosine 5'-triphosphate sodium salt is a Novel, High purity, Activator, High quality, Modified, Ribonucleosides. CAS No. 104809-18-9. Synthetic, DNA, Phosphoramidites. Anticancer, diphosphate. 7-Methylguanosine 5'-triphosphate sodium salt is an antiviral agent that blocks the synthesis of viral RNA or DNA by inhibiting the enzyme ribonucleotide reductase. It is a monophosphate analog of guanosine triphosphate and may be useful in the treatment of cancer or antiviral therapy because it inhibits cell proliferation and induces apoptosis in tumor cells.Formula:C11H18N5O14P3•NaxPurity:Min. 85 Area-%Color and Shape:PowderMolecular weight:537.21 g/mol2',3',5'-Triacetyl -azacytidine
CAS:2',3',5'-Triacetyl-azacytidine is a transcription factor that has dose-dependent effects on the production of melanin. It inhibits the synthesis of melanin by binding to two specific transcription factors, the microphthalmia-associated transcription factor and the histone methyltransferases. This drug also inhibits tyrosinase, which is an enzyme involved in the production of melanin. 2',3',5'-Triacetyl-azacytidine has been shown to inhibit the growth of murine melanoma cells and may be useful for treating skin cancer.Formula:C14H18N4O8Purity:Min. 95%Molecular weight:370.31 g/mol5'-Hydrazino-5'-deoxyguanosine
CAS:Please enquire for more information about 5'-Hydrazino-5'-deoxyguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C10H15N7O4Purity:Min. 95%Molecular weight:297.27 g/mol6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester
CAS:6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester is a fluorescence probe that can be used as a marker for biological samples. It is minimally toxic and stable in vitro, and can be used to measure the protein content of cells. This compound has been used in vitro methods to study the effects of environmental factors on cellular metabolism by measuring the amount of ATP in 3T3-L1 preadipocytes. 6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester has also been used to measure the effectiveness of wastewater treatment processes by analyzing the fluorescence intensity of cells using confocal microscopy. It has also been shown to have an effect on hypersensitivity syndrome and infectious diseases.Formula:C29H19NO11Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:557.46 g/molO6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine
CAS:O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine is a nucleoside phosphoramidite that is used as an antiviral agent. It has been shown to inhibit the replication of RNA viruses and thus inhibit the production of proteins vital for cell division. O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine has also been shown to be an anticancer agent by inhibiting DNA synthesis. This compound is synthesized from deoxyribonucleosides and modified with a benzoyl group at the 6 position on the ribose ring. TheFormula:C38H49N5O7SSi2Purity:Min. 95%Molecular weight:776.06 g/mol1-Methylinosine
CAS:Formula:C11H14N4O5Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:282.262,2-Crylo-5-methyluridine
2,2-Crylo-5-methyluridine is a synthetic diphosphate nucleotide that has been shown to be an activator of DNA synthesis. It is used in the synthesis of oligonucleotides and as a monophosphate for the synthesis of 2'-O-methyl ribonucleosides. 2,2-Crylo-5-methyluridine has been shown to have anticancer activity, which may be due to its ability to inhibit tumor proliferation or induce apoptosis.Purity:Min. 95%2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine
CAS:2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine is an antiviral agent that inhibits the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). It is a synthetic, modified nucleoside. 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine has been shown to be active against human tumor cell lines in vitro and in vivo. The compound inhibits the activity of DNA polymerase and RNA polymerase by competitive inhibition of the enzyme phosphoramidite. 2CECA has also been shown to have anticancer properties as it induces apoptosis in cancer cells.Formula:C15H19ClN6O4Purity:Min. 95%Molecular weight:382.8 g/mol2',3'-Dideoxy-2',3'-didehydro-5-fluoro-uridine,
CAS:2',3'-Dideoxy-2',3'-didehydro-5-fluoro-uridine is a nucleoside that is used as an antiviral agent. This drug has been shown to inhibit the replication of HIV in vitro and in vivo. It has also been shown to be nontoxic and well tolerated in humans, with no adverse effects on white blood cell counts, liver function, or kidney function. The mechanism of action of 2',3'-dideoxy-2',3'-didehydro-5-fluoro-uridine is not known. It may inhibit viral DNA synthesis by blocking the incorporation of uracil into DNA or by inhibiting the activity of RNA polymerase.Formula:C9H9FN2O4Purity:Min. 95%Molecular weight:228.18 g/mol2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It is a modified nucleoside with a purine base. It has been shown to be effective against certain cancer cells in vitro and in vivo. This drug also has antiviral properties, which may be due to its ability to inhibit DNA synthesis through the inhibition of viral RNA replication. 2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine is resistant to phosphorylation by kinase enzymes and it can be used as a precursor for the preparation of other nucleosides.Formula:C11H16N6O4Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:296.29 g/mol2'-Azido-2'-deoxycytidine
CAS:2'-Azido-2'-deoxycytidine is a nucleoside analog derived from cytidine, in which the 2'-hydroxyl group of the ribose is replaced by an azido group (-N₃), while the cytosine base and remaining sugar structure are preserved. This substitution imparts the molecule with bioorthogonal reactivity, enabling its use in chemical biology applications such as nucleic acid labeling via azide-alkyne "click" chemistry. The azido group also sterically and electronically alters sugar conformation and enzymatic recognition, which can affect its incorporation into DNA or RNA by polymerases. Consequently, 2'-azido-2'-deoxycytidine is a useful research tool.Formula:C9H12N6O4Purity:Min. 95 Area-%Color and Shape:Slightly Yellow PowderMolecular weight:268.2 g/mol2'-Deoxycytidine
CAS:Formula:C9H13N3O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:227.222'-Deoxy-L-adenosine
CAS:2'-Deoxy-L-adenosine is an adenosine analogue that has been shown to inhibit the growth of tumor cells in mice. The mechanism of this inhibition is not well understood, but it is thought that 2'-deoxy-L-adenosine inhibits the adenosine A3 receptor and blocks the activation of toll-like receptors. This drug also has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. It has been used as a model system for studying cellular responses to DNA damage caused by ultraviolet radiation. 2'-Deoxy-L-adenosine also has been shown to have a cytotoxic effect on human HL60 cells, which is mediated by nuclear DNA fragmentation.Formula:C10H13N5O3Purity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:251.25 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol
1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol is a modified nucleoside that is used as an anticancer agent. It is a synthetic analogue of 2'-deoxyadenosine 5'-monophosphate (dAMP) and has been shown to be a DNA activator. It also has antiviral properties against herpes simplex virus type 1 and influenza A virus. This drug is a novel high purity and high quality product that can be used for research purposes.Formula:C25H23N5O4Purity:Min. 95%Molecular weight:457.49 g/molL-Adenosine 5'-monophosphate disodium
CAS:L-Adenosine 5'-monophosphate disodium is a high quality, novel, modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. It is also used as an antiviral agent and has anti-cancer properties. L-Adenosine 5'-monophosphate disodium is an activator of ribonucleoside activities and inhibits viral replication by inhibiting the enzyme RNA polymerase. It has been shown to be effective against HIV, herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), influenza A virus, and influenza B virus.Formula:C10H12N5Na2O7PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:391.18 g/mol5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
CAS:5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine is an antiviral monophosphate nucleoside. It has been shown to be a novel, high purity, and CAS No. 251647-50-4. It is a modified nucleic acid analogue that acts as an activator of ribonucleotide reductase and DNA polymerase. The anticancer activity of this product may be due to its ability to inhibit the synthesis of diphosphate nucleotides.Formula:C38H43N5O9Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:713.78 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine
CAS:N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-5-methylcytidine is a nucleoside, which is a compound that consists of a sugar group, one or more phosphate groups, and one or more nucleobases. It is an analogue of cytidine with modifications in the sugar portion and the substitution of 2'-fluoro-5-methyluracil for uracil. This compound has been shown to be effective against cancer cells when used in combination with other anticancer agents. It also inhibits viral replication by acting as a competitive inhibitor of reverse transcriptase, preventing RNA synthesis. This compound also exhibits antiviral activity by inhibiting the synthesis of viral DNA and RNA.Formula:C38H36FN3O7Purity:Min. 95%Molecular weight:665.72 g/mol2-Amino-2'-deoxyadenosine
CAS:2-Amino-2'-deoxyadenosine is a modified nucleoside, closely related to adenosine in which the 2'-hydroxyl group is replaced by an amino group. This compound has potential research applicationsFormula:C10H14N6O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:266.26 g/molN2-DMF-guanosine
N2-DMF-guanosine is a novel antiviral agent that has been synthesized by modifying the nucleoside guanosine. It is an analog of guanosine in which the 2'-hydroxyl group has been replaced with a 2'-deoxy-2'-fluoro group, and it inhibits viral replication by inhibiting viral DNA polymerase. N2-DMF-guanosine is also used as a high quality deoxyribonucleoside monophosphate for the synthesis of ribonucleosides and nucleosides. This compound has a CAS number of 6074-37-4.Formula:C13H18N6O5Purity:Min. 95%Molecular weight:338.32 g/mol1-Methyl-3-(3-amino-3-carboxypropyl)pseudouridine
CAS:1-Methyl-3-(3-amino-3-carboxypropyl)pseudouridine is a nucleoside analog for use in research into biological functions. Pseudouridine is a modified version of uridine found in certain types of RNA e.g. tRNA. This nucleoside analog could be used for research into how alteration to RNA structures can impact cellular function.Formula:C14H21N3O8Purity:Min. 95%Color and Shape:PowderMolecular weight:359.33 g/mol5'-O-p-Anisoyl-2'-deoxyuridine 3'-CE phosphoramidite
5'-O-p-Anisoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer nucleoside analog that inhibits viral replication. It is a modified nucleoside with a 5' anisoyl group and a 2' deoxyuridine moiety. This compound is synthesized by reacting the 5'-O-p-anisoyl-2'-deoxyuridine 3'-cyclohexylphosphate with phosphorus oxychloride to form the 5'-O-p-anisoyl-2'-deoxyuridine 3'-cyanoethyl phosphoramidite, which can be used for the synthesis of DNA or RNA. The phosphoramidite can also be used as an activator in polymerase chain reactions (PCR).Formula:C26H35N4O8PPurity:Min. 95%Molecular weight:562.55 g/mol5'-Tosyl-2'-deoxycytidine
CAS:5'-Tosyl-2'-deoxycytidine is a nucleoside with anticancer activity and is a novel derivative of cytidine. It has been shown to inhibit the proliferation of human cancer cells in culture. 5'-Tosyl-2'-deoxycytidine is also an antiviral agent that inhibits the synthesis of viral DNA by inhibiting the enzyme RNA polymerase. This product is synthetic, water soluble, and stable at pH 2.0 to 10.5, making it suitable for use in pharmaceutical formulations. The purity of this product is high and its chemical structure has been modified from cytidine to increase its stability against degradation by intracellular phosphatases.Formula:C16H19N3O5SPurity:Min. 95%Molecular weight:365.41 g/mol3'-O-Methyladenosine
CAS:3'-O-Methyladenosine (3'OMeA) is a monomethylated adenosine that belongs to the group of nucleosides. It has been found to inhibit the activity of adenosine receptors, which are important for the regulation of blood pressure and central nervous system function. 3'OMeA also inhibits virus replication in human lymphocytes. 3'OMeA is synthesized by reaction with methylamine and purification by column chromatography. The molecule is a potential therapeutic target for HIV/AIDS, as it can be used as a specific agonist in order to block viral entry into cells.Formula:C11H15N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:281.27 g/mol9H-Purin-2-amine, 6-chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-
CAS:Formula:C16H18ClN5O7Purity:97%Color and Shape:SolidMolecular weight:427.79642',5'-Dideoxyuridine
CAS:2',5'-Dideoxyuridine is a synthetic nucleoside analog derived from uridine, one of the four standard nucleosides found in RNA. It is chemically modified by the removal of hydroxyl (-OH) groups at the 2' and 5' positions of the sugar, altering its ability to participate in RNA or DNA chain formation.Formula:C9H12N2O4Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:212.21 g/mol5’-Deoxy-5’-iodo-2’-O-methyluridine
CAS:5’-Deoxy-5’-iodo-2’-O-methyluridine is a nucleoside that is modified with the substitution of an iodine atom for a hydrogen atom on the 5′ carbon. It has antiviral and anticancer properties. The high purity and novel structure make this compound useful in DNA synthesis. This product can also be used as a phosphoramidite or deoxyribonucleoside building block in DNA synthesis.Purity:Min. 95%2'-Deoxy-5'-O-DMT-N2-isobutyryl-O6-methylguanosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N2-isobutyryl-O6-methylguanosine 3'-CE phosphoramidite is a modified nucleoside that can be used in the synthesis of DNA. It is a modified nucleoside with a methyl group at the 2' position and an isobutyryl group at the 6' position. The methyl group is attached to the 5' carbon atom of the ribose sugar, and the isobutyryl group is attached to the 2' carbon atom. This product has anticancer activity, as well as antiviral, antibacterial, and antifungal properties. It has been shown to inhibit transcription by binding to RNA polymerase II in vitro and in vivo. This product also has high purity and high quality for research purposes.Formula:C45H56N7O8PPurity:Min. 95%Color and Shape:Off-White To Light (Or Pale) Brown SolidMolecular weight:853.96 g/molN6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite
CAS:N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite is an antiviral agent that inhibits the activity of viral DNA polymerase. This chemical has been shown to be effective against herpes virus, pox virus and HIV. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite is a novel nucleotide analogue that contains a modified deoxyribose sugar backbone. It has been shown to be active against cancer cells in vitro, but not in vivo.Formula:C47H51FN7O7PPurity:Min. 95%Color and Shape:PowderMolecular weight:875.95 g/molN6-Benzoyl-3'-O-benzoyl-2'-deoxyadenosine
6-Benzoyl-3'-O-benzoyl-2'-deoxyadenosine (BBD) is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and also a novel monophosphate nucleotide. BBD has been shown to inhibit the replication of RNA in cells infected with HIV and HSV.Purity:Min. 95%2''-Deoxy-5''-O-DMT-N2-methylguanosine 3''-CE phosphoramidite
CAS:Formula:C41H50N7O7PPurity:≥ 95%Color and Shape:White powder or solidMolecular weight:783.85Guanosine 2',3'-cyclic phosphate triethylamine salt
CAS:Guanosine 2',3'-cyclic phosphate triethylamine salt is a synthetic nucleoside that has antiviral and anticancer activity. It is a modified nucleoside with a cyclic phosphate group attached to the 2' position of the sugar ring. This modification prevents hydrolysis of the nucleotide by phosphodiesterases, which are enzymes that break down RNA and DNA. Guanosine 2',3'-cyclic phosphate triethylamine salt has been shown to be active against HIV-1, herpes simplex virus type 1 (HSV-1), HSV-2, and cytomegalovirus (CMV). It also inhibits the proliferation of various cancer cell lines including those from breast, prostate, lung, colon, and leukemia.Formula:C16H27N6O7PPurity:Min. 95%Molecular weight:446.4 g/molQueuosine
CAS:Queuosine is a modified purine nucleoside that is found in the cell-wall peptidoglycan of bacteria. It can be synthesized by the enzymatic conversion of inosine to queuosine with sodium citrate, or it can be obtained from bovine fetal calf serum that has been treated with queuine (a natural amino acid). The reaction mechanism for this conversion is not well understood but it has been shown that queuosine has a number of enzyme activities, including nucleotide phosphoribosyltransferase, mitochondrial functions and eukaryotic DNA synthesis. Queuosine also has a redox potential between -0.2 and -1.8 volts, which makes it an effective antioxidant. Queuosine's antioxidant properties may be due to its ability to donate a pair of electrons to reduce molecular oxygen to hydrogen peroxide, which can then be converted into water by superoxide dismutase or glutathione perFormula:C17H23N5O7Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:409.39 g/molInosine 2',3'-cyclic monophosphate sodium salt
CAS:Inosine 2',3'-cyclic monophosphate sodium salt (ICMP) is a phosphodiesterase inhibitor that inhibits the activity of protein kinases and phosphatases. ICMP is used in biochemical studies to inhibit tryptophan metabolism and protein synthesis. It also has been shown to be useful in the study of sequences, such as those found in DNA and RNA. ICMP has been shown to increase the mRNA levels of a number of proteins at lower concentrations than other inhibitors, making it a valuable tool for studying protein synthesis. The enzyme-inhibiting properties of ICMP have been observed in calf thymus DNA and bacterial DNA gyrase, dna topoisomerase, and rna synthesis. ICMP also inhibits caenorhabditis elegans phosphatases and can be used in genetic engineering experiments involving Xenopus oocytes.Purity:Min. 95%2-Amino-4-(4-bromophenyl)pyrimidine
CAS:2-Amino-4-(4-bromophenyl)pyrimidine is a phosphoramidite, modified nucleoside. It is an antiviral and anticancer agent that inhibits DNA synthesis. 2-Amino-4-(4-bromophenyl)pyrimidine is a novel nucleotide analog with the ability to inhibit replication of RNA and DNA in vitro. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), cytomegalovirus (CMV), and HIV in cell culture. Furthermore, this phosphoramidite has been shown to have no detectable toxicity in mice at doses up to 2000 mg/kg.Formula:C10H8BrN3Purity:Min. 95%Molecular weight:250.09 g/mol2'-Deoxyadenosine 5'-monophosphate sodium salt
CAS:2'-Deoxyadenosine 5'-monophosphate sodium salt is a hydrated salt that is the sodium salt of 2'-deoxyadenosine 5'-monophosphate. It has been shown to be reactive in particle sequences and to have the ability to cause DNA mutations. Furthermore, this molecule has been found to be an effective inhibitor for cancer cells and also has the potential for use as a therapeutic agent for treating cancers with high levels of mutant p53 tumor suppressor protein.Formula:C10H14N5O6P·xNaPurity:Min. 95%Color and Shape:PowderMolecular weight:331.22 g/mol8-Bromo-2'-deoxyguanosine
CAS:8-Bromo-2'-deoxyguanosine is a reactive brominated compound that has been shown to stabilize DNA strands. The effects of 8-bromo-2'-deoxyguanosine on the stability of DNA are due to the steric interactions between the bromine and amines in the DNA backbone, which prevent nucleophilic attack. 8-Bromo-2'-deoxyguanosine is an antihistamine, but it has also been used as a precursor for other drugs such as zidovudine, an antiviral drug used in HIV/AIDS therapy. It has also been proposed as a potential treatment for atherosclerosis.Formula:C10H12BrN5O4Purity:Min. 90 Area-%Color and Shape:Off-White PowderMolecular weight:346.14 g/mol9-(3'-O-Methyl-b-D-xylofuranosyl)adenine
9-(3'-O-methyl-β-D-xylofuranosyl)adenine is a synthetic nucleoside that is an activator of viral DNA polymerase. 9-(3'-O-methyl-β-D-xylofuranosyl)adenine is a novel nucleoside that has been shown to be active against both DNA and RNA viruses. This compound also has anticancer activity. 9-(3'-O-methyl-β-D-xylofuranosyl)adenine is the phosphorylated form of adenine and has high purity and quality. The CAS number for this product is 53110-86-2.Purity:Min. 95%5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile
CAS:5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile is a nucleoside phosphoramidite that is synthesized from 2'-deoxyribose, 5'-iodoimidazole and triacetic acid. This compound is a novel phosphoramidite and can be used to synthesize DNA or RNA molecules. It has been shown to have anticancer properties, which may be due to its ability to inhibit DNA replication. 5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile also has antiviral properties and can be used as an activator in the synthesis of modified nucleosides.Formula:C15H16IN3O7Purity:Min. 95%Molecular weight:477.21 g/mol2'-Deoxy-3'-O-DMT-N2-Isobutyrylguanosine
CAS:2'-Deoxy-3'-O-DMT-N2-Isobutyrylguanosine is a synthetic nucleoside that has the ability to activate and inhibit the growth of cancer cells. This compound is a phosphoramidite, and it has been modified by the addition of an isobutyrate group at the 2' position. The structure of this nucleoside is similar to that of natural guanosine, but with an additional 2' oxygen atom. This modification can be used for inhibition of DNA synthesis in cells and may have antiviral effects.Formula:C35H37N5O7Purity:Min. 97 Area-%Molecular weight:639.71 g/mol5-Iodo-2’-C-methylcytidine
CAS:5-Iodo-2’-C-methylcytidine is a synthetic nucleoside that is an activator of DNA polymerases. It has been shown to be an anticancer agent and antiviral agent, with potential applications in the treatment of HIV and HBV infections. 5-Iodo-2’-C-methylcytidine is a novel monophosphate nucleoside that has been modified to improve its stability. This product is sold as a high purity, high quality, NMR grade material that can be used in research or in the manufacture of pharmaceuticals.Formula:C10H14IN3O5Purity:Min. 95%Molecular weight:383.14 g/mol1-(3'-5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-alpha-L-arabinofuranosyl)thymine
1-(3'-5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-alpha-L-arabinofuranosyl)thymine is a nucleoside analog with modifications that influence its biological activity. It is made up of a thymine base, benzoyl groups that protect hydroxyl functionalities during chemical synthesis and a α-L-linkage, which impacts its biological interactions compared to β-L-nucleosides. This molecule also contains the sugar 2'-Deoxy-2'-fluoro-α-L-arabinofuranose which has a L-arabinose configuration, an α-Anomeric linkage and a 2'-Fluoro substitution. The latter modification has the potential to increase the molecule's metabolic stability and resistance to enzymatic degradationFormula:C24H21FN2O7Purity:Min. 95%Molecular weight:484.89 g/mol7-Allyl-7,8-dihydro-8-oxoguanosine
CAS:Agonist of toll-like receptors TLR7Formula:C13H17N5O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:339.3 g/mol8-Bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine
CAS:8-Bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine is a nucleoside analog that is structurally related to 2'-deoxyguanosine. It has the chemical name 8-bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine and the structural formula C8H14BrNO3. This compound is an antiviral agent which inhibits DNA replication by inhibiting DNA polymerase, RNA synthesis by inhibition of ribonucleotide reductase, and protein synthesis by inhibition of aminoacyl tRNA synthetases. It also binds to viral dsDNA and prevents viral replication.Formula:C13H17BrN6O4Purity:Min. 95%Molecular weight:401.22 g/molGuanosine 5'-monophosphate disodium salt
CAS:Guanosine 5'-monophosphate disodium salt (GMPDS) is an antiviral agent that inhibits the synthesis of viral nucleic acids by competitive inhibition of the enzyme ribonucleotide reductase. GMPDS has been shown to inhibit the replication of a number of RNA viruses, including influenza A and B, herpes simplex virus type 1, and human immunodeficiency virus type 1. This drug also has been shown to decrease cyclic adenosine monophosphate (cAMP) levels in cells by inhibiting phosphodiesterase activity. GMPDS is used for treatment of infectious diseases such as influenza A, herpes, and HIV-1.Formula:C10H12N5Na2O8PPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:407.18 g/mol2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine
2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine is an antiviral drug that is an analogue of adenosine. It has been shown to be a potent activator of the immune system and also has anticancer properties. 2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine is synthesized from 2',3'-dideoxyadenosine and 2,6 diaminopurine riboside by the use of activated phosphoramidites in a modified nucleoside synthesizer. The CAS number for this compound is 70717-54-8.Purity:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.Purity:Min. 95%a-Adenosine
CAS:a-Adenosine is a nucleoside that has been shown to have anti-cancer properties. It inhibits the proliferation of squamous carcinoma cells by irreversibly inhibiting adenosine deaminase, which converts adenosine to inosine, as well as other enzymes such as DNA polymerase and ribonucleotide reductase. The reaction mechanism for this inhibition is not yet fully understood, but it may be related to the inhibition of camp levels or receptor activity. a-Adenosine has also been shown to have anti-microbial properties against bacteria, fungi and yeast. It inhibits the growth of these microorganisms by binding to their cell walls and preventing protein synthesis. This drug is rapidly hydrolyzed in vivo and has an antimicrobial effect at physiological concentrations. A more potent analog of a-adenosine (a-adenosinium) has been developed that can inhibit epidermal growth factor (EGF).Formula:C10H13N5O4Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:267.24 g/molUridine 5'-monophosphate disodium
CAS:Uridine 5'-monophosphate disodium salt (UDP-MS) is a structural analog of uridine that is used as a dietary supplement. It has been shown to inhibit phosphodiesterases and cyclic nucleotide phosphodiesterases, which are enzymes that degrade the secondary messenger, cyclic adenosine monophosphate (cAMP). This inhibition leads to increased levels of cAMP in cells, which stimulates protein kinase A activity and promotes cellular differentiation. The analysis of UDP-MS has been performed using liquid chromatography with ultraviolet detection.Formula:C9H11N2Na2O9PPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:368.15 g/mol