Nucleosides

2’-Deoxy-2’-fluoro nucleosides and nucleotides have been shown to demonstrate anti-viral activity against influenza, SARS and HIV. More specifically the phosphonate of 2'-Deoxy-2'-fluoroadenosine has been evaluated as an inhibitor of Hepacivirus C (HCV).

2'-Deoxy-5'-O-DMT-5-iodocytidine is a modified nucleoside that has antiviral and anticancer properties. 2'-deoxy-5'-O-DMT-5-iodocytidine is able to activate the DNA polymerase, ribonucleotide reductase, and deoxyribonucleotide reductase enzymes. This product can be used as a monophosphate or diphosphate. The CAS number for this compound is 141475-07-4.

2'-O-Methyl-2-thiouridine is a modified nucleoside that is categorized as a mismatched nucleotide. It is found in RNA, where it replaces uridine and acts as a mismatch base. 2'-O-Methyl-2-thiouridine has been shown to stabilize duplex DNA against thermal denaturation by forming triplexes with complementary sequences. It also stabilizes dsDNA against hydrolysis by the enzyme ribonuclease H (RNase H) and has been used in the design of antisense therapeutics. Thermophilic bacteria use this molecule to synthesize their own thymine nucleotides, which are structurally similar to 2'-O-methyl-2-thiouridine. This modification prevents mismatches in their own dna and helps protect them from heat stress. The thermodynamic stability of this molecule has been calculated using an algorithm that takes into account the hybridization free energy, enthalpy change, entropy

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5-Iodo-2’-O-methylcytidine is a nucleoside that is used as an activator for the synthesis of ribonucleosides. It is also used in the synthesis of DNA, RNA, and phosphoramidites. 5-Iodo-2’-O-methylcytidine has shown anticancer activity against a variety of cancer cell lines. This novel nucleotide exhibits high quality and purity, with an excellent yield and low impurities. The compound has been assigned CAS No. 847650-69-5 and its physical properties have been described in detail.

Cholest-5-en-3-ol, 3-CEphosphoramidite is a modified nucleoside that is used in the synthesis of DNA and RNA. It has antiviral and anticancer properties. Cholest-5-en-3-ol, 3-CEphosphoramidite inhibits tumor growth by inhibiting DNA synthesis in cells. The drug also has antiviral activity because it inhibits viral replication by blocking the incorporation of deoxyribonucleotides into viral DNA. Cholest-5-en-3-ol, 3-CEphosphoramidite can be used in the synthesis of oligodeoxyribonucleotides containing modified bases or phosphodiester linkages or both. It is also used to synthesize other novel compounds with anticancer properties.

Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.

2'[3']-O-Acetyl-N6-benzoyl-5'-O-DMT-adenosine 3'[2]-O-succinate triethylamine salt is a phosphoramidite that can be used in the synthesis of oligonucleotides. It has antiviral activity and is an activator of ribonucleoside diphosphates. This product is novel and has not been previously described in any literature. The CAS number for this product is 68424-02-4.

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 2'-CE phosphoramidite is a modified nucleoside that is commonly used in the synthesis of DNA. It is a monophosphate, diphosphate, and triphosphate analog of uridine. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 2'-CE phosphoramidite has antiviral and anticancer activity, as well as antitumor properties. This product is available in high purity and high quality.

N3-Methyluridine is a monosodium salt of N3-methyluridine, which is an analogue of uridine. It is a nucleoside that is used as a precursor for RNA synthesis. In the body, N3-methyluridine is converted to uridine and then phosphorylated to form UMP. The phosphate group on UMP can be hydrolyzed by the enzyme kinase in order to produce ATP. N3-Methyluridine has been shown to be a potential biomarker for metabolic disorders and drug interactions with drugs such as loperamide, which inhibit mitochondrial function by inhibiting the enzyme p2y receptors.

2',3',5'-Tri-O-acetylguanosine is a protected form of the nucleoside guanosine which has potential application as a synthetic intermediate in nucleic acid and nucleoside chemistry.

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2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite is a modified nucleotide that has been used in the synthesis of DNA. It is a monophosphate, diphosphate, and nucleoside. This compound has also been shown to be an activator for the ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite has CAS number 55913-85-5.

N6-Benzoyl-9-(a-D-mannopyranosyl)adenine is a novel, synthetic nucleoside analog. It is an antiviral drug that inhibits viral replication by replacing the natural substrate in DNA synthesis. N6-Benzoyl-9-(a-D-mannopyranosyl)adenine has been shown to be effective against human leukemia cells and to have anticancer properties. This drug also stimulates the immune system by triggering the production of antibodies and other immunoglobulins.

N2-Isobutyryl-O6-cyanoethyl-7’-OH-N-trityl-morpholino guanine is a nucleoside, ribonucleoside, and anti-cancer drug. It is modified with two acyl groups at the 2′ position of the sugar moiety and contains a phosphoramidite group in the 5′ position. N2-Isobutyryl-O6-cyanoethyl-7’-OH-N-trityl -morpholino guanine is an activator of DNA synthesis in vitro. In vivo studies have shown that N2-Isobutyryl O6 cyanoethyl 7' OH N trityl morpholino guanine can be used as an anticancer agent against human breast cancer cells.

LDA is a technique for extracting spectral features from a set of spectra. It uses the probabilistic model of discriminant analysis to discriminate between groups of spectra. LDA has been shown to outperform other techniques, such as PCA and MDA, in analyzing datasets with a small number of variables. The algorithm is incrementally updated with new data points and parameters, which makes it an attractive choice for real-time applications.

6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analogue that inhibits the replication of the hepatitis C virus. It binds to the viral RNA polymerase and blocks the synthesis of viral RNA, thereby preventing infection. This drug also has antiviral activity against HIV and herpes simplex viruses. The antiviral effect is due to its ability to inhibit phosphatases and carboxylates, which are involved in the initiation of mRNA transcription and protein translation, respectively. 6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is metabolized by deoxyadenosine kinase into 6-chloropurine ribonucleotide, which can be converted into other purines.

2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a synthetic purine nucleoside analog. The fluorine substitution and sugar modification allow it to mimic natural nucleosides but disrupt DNA or RNA synthesis when incorporated. The fluorine makes the molecule more chemically stable and can influence how enzymes interact with it. Like other nucleoside analogs, it has the potential to act as a chain terminator or inhibit key enzymes like polymerases or reverse transcriptases.

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2'-Deoxy-8-oxo-6-thioguanosine 5'-triphosphate is a synthetic nucleotide that has antiviral properties. It activates the transcription of genes by preventing the synthesis of viral DNA and RNA. 2'-Deoxy-8-oxo-6-thioguanosine 5'-triphosphate is also an anticancer agent, as it prevents cell proliferation by inhibiting the synthesis of DNA, RNA, and protein. This drug can be used for treatment of HIV infection or cancer. 2'-Deoxy-8-oxo-6-thioguanosine 5'-triphosphate is a novel nucleotide with high purity.

4-Amino-2-methoxypyrimidine is a fluorescent compound that is used for the detection of hydrogen bonds, and as a precursor in the synthesis of other compounds. 4-Amino-2-methoxypyrimidine has been shown to be able to absorb ultraviolet radiation, which leads to its fluorescence. The compound can also form hydrogen bonds with other molecules and it has been shown to react with n-hexane. 4-Amino-2-methoxypyrimidine reacts with orthophosphate, producing singlet oxygen and transferring a proton. It also reacts with solvents such as water or ethanol, giving off light.

6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.

2',3'-Di-O-acetyl-5'-O-DMT-5-methyluridine is a monophosphate nucleotide, which is an antiviral agent. It is a novel, high quality and high purity compound. The CAS number for 2',3'-Di-O-acetyl-5'-O-DMT-5-methyluridine is 69681-06-8. It has antiviral activity against the herpes simplex virus type 1 (HSV1) and Epstein Barr virus (EBV). This drug also inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. This product can be used in research to synthesize phosphoramidites, activator molecules, and nucleosides.

5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine is a nucleoside that has been synthesized using an oxime opening of the 5' position and a methylation at the 2' position. It has been shown to have an affinity for tissues in a chemotactic assay. The compound is minimised to remove non-specific binding sites, avoiding false positives on the checklist. This molecule has been analysed with fluorescence spectroscopy and microscopy techniques, which revealed that it is distributed in tissues as well as being found in dragonflies. It was also shown to be transduced by muscle cells and geochemically detected in limestone from China.

Biotinyl coenzyme A is a novel, synthetic nucleotide that has activity against cancer cells. It is an analogue of biotin-diphosphate with a ribonucleoside moiety attached to the diphosphate. Biotinyl coenzyme A is phosphoramidite monophosphate, which can be synthesized by modifying the 5'-terminus of the anticancer drug gemcitabine.

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Anti-viral; reverse transcriptase inhibitor

2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a purine nucleoside where the purine base has a 2-amino group at position 2 and a chlorine at position 6. The sugar is 2'-deoxy, meaning it is like the sugar found in DNA, lacking the 2'-hydroxyl group that is present in RNA. The amino and chloro groups on the purine base modify how this molecule behaves in biological systems making it useful in research applications.

N6-Benzoyl-5'-O-benzyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite is an activator of ribonucleosides and deoxyribonucleosides. It is a novel synthetic nucleoside, which has high quality and purity. The chemical modification of the base allows for the synthesis of DNA with modified bases. This product has been shown to have anticancer effects in vitro and in vivo, as well as antiviral activities against HIV.

5-Methyl-4'-thiouridine is a novel, synthetic nucleoside that has antiviral and anticancer activities. It is an activator of ribonucleotide reductase and a substrate for diphosphate reductase. 5-Methyl-4'-thiouridine (also known as 5-methyluridine) is used in the synthesis of DNA, RNA, and phosphoramidites. The CAS number for this compound is 6741-71-5.

5-Aminomethyluridine is a chemical compound that is involved in protein synthesis. It has been shown to inhibit the production of methylated uridines and cytosine, as well as the formation of 5-methylcytosine by methyltransferase. It also inhibits protein synthesis in human cells. 5-Aminomethyluridine may be able to block the progression of infectious diseases by inhibiting protein synthesis in the host cell. The compounds have been shown to inhibit the catalytic subunit of ribonucleotide reductase and RNA polymerase II, which are vital for cellular replication.

2'-Deoxyuridine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution is an activator of nucleoside diphosphates. It is a novel and anticancer nucleoside analog with high purity, high quality and a CAS number of 170428-84-9. This activator has been shown to inhibit the growth of tumor cells by inhibiting DNA synthesis and ribonucleotide reductase activity. The 2'-deoxyuridine-5'-[(a,b)-methyleno]triphosphate sodium salt - 10 mM aqueous solution can be used in the synthesis of deoxyribonucleosides and phosphoramidites as well as modified DNA.

N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is a novel modified nucleoside that has been shown to inhibit the replication of HIV and other viruses. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is an activator for DNA synthesis. This drug binds to the ribonucleotide reductase enzyme, which is required for the conversion of ribonucleotides into deoxyribonucleotides, and inhibits the enzyme's activity. The acetyl group on this drug prevents it from being incorporated into DNA or RNA. This drug can be used as an antiviral or anticancer agent.

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4',5'-Didehydro-5'-deoxy-2'-O-methyluridine is a novel nucleoside phosphoramidite. It is a monophosphate, high purity and high quality. 4',5'-Didehydro-5'-deoxy-2'-O-methyluridine is an activator of DNA polymerase and can be used in the synthesis of DNA. 4',5'-Didehydro-5'-deoxy-2'-O-methyluridine also has antiviral properties and can be used to synthesize deoxyribonucleosides. It has been modified to have a diphosphate group at the 5' end, which allows it to be incorporated into DNA during synthesis.

Adenylosuccinic acid (Adenylosuccinate) is a purine nucleotide metabolic intermediate and a novel inducer of the Nrf2 cell protector.

2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate is an antiviral nucleoside with anticancer properties that is synthesized from 2'-deoxyuridine monophosphate and 5-methyluridine. This novel compound has shown antiviral activity against HIV, herpes simplex virus type 1, and herpes simplex virus type 2. It also inhibits the growth of human breast cancer cells in vitro.

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil is a nucleoside analog and contains a uracil base, and a 2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl sugar moiety. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activities. The incorporation of fluorine into nucleoside analogs can also affect their interaction with DNA and RNA, leading to changes in their therapeutic potential.

2'-Deoxyadenosine 5'-O-thiophosphate sodium salt is a synthetic nucleotide that has antiviral, anticancer and antitumor properties. It is a modified deoxyribonucleoside and it activates the synthesis of DNA by acting as an activator. This drug is not found in nature and it has shown to inhibit the growth of human breast cancer cells in cell culture.

6-Chloro-9-(2-deoxy-b-L-erythro-pentofuranosyl)-9H-purin-2-amine is a novel antiviral and anticancer agent. It is an analog of adenosine that inhibits viral replication by inhibiting DNA synthesis. 6CePP2A is an activator of nucleoside deoxyribonucleotidyltransferase, which converts dATP to dTTP.

N4-p-Anisoylcytidine is a labile, crystalline, and water soluble oligoribonucleotide. It is an intermediate in the synthesis of cytidine and phenyl ring. N4-p-Anisoylcytidine can be prepared by reacting p-anisic acid with 4-benzoylcytosine. The reaction yields a mixture of products that can be purified by recrystallization or chromatography. It is hydrolyzed by acidic conditions to yield cytidine and phenyl ring. N4-p-Anisoylcytidine has been used as an intermediate in the synthesis of cytidine, which is subsequently converted to phenyl ring by reaction with benzene. This compound also has been used as an esterification agent for orthoesters.

N4-Benzoyl-2'-deoxy-5'-O-levulinoylcytidine-3'-CE phosphoramidite is a novel nucleoside analogue that is synthesized by coupling the 5'-O-levulinoyl group to the 3'-OH of cytidine. The compound has antiviral and anticancer activity, as well as potential for use in gene therapy. It is synthesized from commercially available deoxyribonucleosides, an activator, and a diphosphate. The product is purified to high purity and quality, with dsDNA conversion yields of more than 90%.

Polyinosinic-polycytidylic acid sodium salt is a synthetic nucleoside analog that inhibits the synthesis of viral RNA. It is a potent inhibitor of tumor cells and is used in cancer treatment. Polyinosinic-polycytidylic acid sodium salt is a cellular toxin and an inducer of apoptosis, which may be mediated by mitochondrial dysfunction and caspase activation. The drug can also induce an immune response in muscle tissue against viruses and tumors, making it useful as a vaccine adjuvant. The drug has been shown to have antitumor effects in mice with sarcoma 180 cells injected into the muscle.

8-Benzyloxy-9-(beta-D-xylofuranosyl)guanine (8BXG) is a novel nucleoside analog that inhibits the growth of cancer cells. It binds to the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, thus preventing cell proliferation. 8BXG has been shown to inhibit viral replication in vitro with high potency. This compound is a monophosphate, which can be phosphorylated by adenosine kinase to form its active form. 8BXG is also an activator of ribonucleotide reductase in vitro, leading to increased anticancer activity.

2'-Deoxy-2'-fluoroadenosine-5'-triphosphate is an analog of adenosine triphosphate (ATP). It inhibits the synthesis of RNA by binding to the ribonucleotide reductase enzyme. This inhibition leads to the inhibition of DNA synthesis, which in turn prevents cell division and/or causes cell death. The inhibitory effect of 2'-deoxy-2'-fluoroadenosine-5'-triphosphate on protein and DNA synthesis has been shown in vivo and in vitro using cell culture techniques. This compound inhibits topoisomerase II, a key enzyme in DNA replication, at high concentrations.

3’-Deoxy-5-fluoro-3’-methyluridine is a nucleoside that has antiviral and anticancer properties. It is synthesized from 5-fluorouracil, which is a prodrug that is activated by 3’-deoxy-5-fluoro-3’-methyl uridine to produce 5′,6′ difluorodeoxyadenosine. This compound can be used in the treatment of hepatitis B virus and hepatitis C virus infections. 3’-Deoxy-5-fluoro-3’ methyluridine has also been shown to inhibit the growth of cancer cells in vitro.

6-Benzylamino-9-(b-D-arabinofuranosyl)purine is a nucleoside that is used as an activator and as an antiviral agent. It has been used in anticancer research, but it has not been found to have any significant effect against cancer cells. 6-Benzylamino-9-(b-D-arabinofuranosyl)purine is a modified ribonucleoside with a boronic acid group attached to the 9 position of the purine ring. This modification leads to increased stability of the nucleotide in alkaline conditions and improved cellular uptake. 6-Benzylamino-9-(b-D-arabinofuranosyl)purine can be phosphorylated on the 2',3' and 5' positions, forming 2',3'-diphosphate, 3'-diphosphate and 5'-triphosphate derivatives.

5-Chloro-2',3'-O-isopropylideneuridine (5Cl-2',3'-O-diP) is a nucleoside that is used in the synthesis of DNA and RNA. It can be phosphorylated to 5Cl-2',3'-O-[(beta, gamma)-di]P, which is an antiviral agent. 5Cl-2',3'-O-diP inhibits the growth of tumor cells in vitro and has been shown to be effective against herpes simplex virus type 1 (HSV1) at low concentrations. This drug also shows anticancer properties, with a potency similar to that of adriamycin. 5Cl-2',3'-O-diP is a novel synthetic nucleoside that has not been reported in the literature before.

2',3',5'-Tri-O-benzoyl-N6-benzyl-2'-C-methyladenosine is an adenosine analog for potential use in research into antiviral drug development or nucleoside analogs.

2,2’-Anhydro-5’-O-DMT-uridine is a high purity synthetic nucleoside that is modified with a hydroxymethyl group in the 2' position. It is a monophosphate and diphosphate derivative of uridine. This nucleoside has antiviral and anticancer properties, as well as the ability to inhibit HIV replication.

Emtricitabine is a nucleoside reverse transcriptase inhibitor with activity against human immunodeficiency virus and hepatitis B virus

N4-Benzyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel nucleoside with antiviral and anticancer activity. It has been found to be an activator of DNA synthesis and a monophosphate at the 5' end. This product is synthesized by reacting 4-benzyl-2'-deoxycytidine with chloroacetic acid in the presence of a base, such as triethylamine or diisopropylethylamine. The CAS number for this product is not currently available.

6-Chloro-9-methylpurine is an inhibitor of the enzyme kinase. It has been shown to inhibit the activity of 6-chloropurine phosphohydrolase and 6-chloropurine nucleoside phosphorylase, which are important enzymes in purine metabolism. 6-Chloro-9-methylpurine can be used to treat a number of diseases, including myeloid leukemia, where it inhibits the production of nucleic acids. This drug has also been shown to inhibit the growth of lettuce by inhibiting chlorophyll synthesis.

N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleoside. It is an activator of DNA and RNA synthesis, which can be used to synthesize deoxyribonucleosides and ribonucleosides. This compound has been shown to have anticancer and antiviral properties. N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is also used as a high quality synthetic building block for the synthesis of phosphoramidites.

5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil is a modified nucleoside that is phosphorylated and activated to 5'-triphosphate. It has antiviral, anticancer, and antimalarial activities.

2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.

Malonyl coenzyme A lithium salt - 90% is a fatty acid that is involved in the biosynthesis of fats. It is also involved in the synthesis of prostaglandins, which are hormone-like substances that have a wide variety of effects on many different tissues. Malonyl coenzyme A lithium salt - 90% may be useful for the treatment of insulin resistance and obesity due to its ability to stimulate glucose uptake by fat cells and increase insulin sensitivity. The following product details are for a supplement:

2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine is a novel modified nucleoside with antiviral and anticancer activities. It is synthesized from 2'-deoxyuridine monophosphate, which is activated with bis(trimethylsilyl)acetamide (BSA). This nucleoside has been shown to inhibit the growth of cancer cells in vitro and in vivo.

2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine 3'-CE phosphoramidite is a novel, high quality nucleoside that is synthesized by the reaction of 5'-O-DMT-2'-deoxyguanosine with isobutyryl chloride. It has antiviral and anticancer properties and has been shown to be an activator of RNA polymerase. CAS number: 89879-16-1

2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a novel nucleoside analogue that inhibits the proliferation of cancer cells. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides and thereby prevents viral replication. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine has antiviral activity against influenza A virus and herpes simplex virus type 1 (HSV-1) in cell culture. This drug also has an inhibitory effect on the DNA polymerases and other enzymes involved in DNA synthesis. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a high quality product with high purity, CAS No. 1000203-40-6.

1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole is a nucleoside that can be used as an activator for phosphoramidite synthesis. It is also known to have antiviral, anticancer, and antimalarial properties. 1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole has been shown to inhibit the proliferation of human leukemia cells in culture. It has also been shown to suppress HIV replication in vitro by inhibiting viral RNA synthesis.

1-b-D-Arabinofuranosyluracil 5'-monophosphate is a pyrimidine nucleotide analog. Because of its structural similarity to natural nucleotides, it can interact with enzymes involved in nucleic acid synthesis. It is also a metabolite of Ara-U (arabinosyluracil), which is itself a compound studied for its biological activity. Scientists could potentially use this molecule in research to study how cells process and use nucleotides, and to understand how changes in nucleotide structure can affect biological processes.

Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is an antiviral nucleoside that has been shown to inhibit HIV and HCV replication in vitro. It also inhibits the proliferation of cancer cells in vitro and induces apoptosis in vivo. Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a novel nucleoside that was designed for use as an anticancer agent. The compound can be used to modify DNA or RNA molecules at the ribonucleotide or deoxyribonucleotide level.

N6-Benzoyl-3'-O-benzyl-5'-O-DMT-adenosine is a modified nucleoside that is synthesized by the phosphoramidite method. It has antiviral activity and can be used as an anticancer drug. N6-Benzoyl-3'-O-benzyl-5'-O-DMT-adenosine has been shown to inhibit the growth of cancer cells in vitro. The compound also inhibits DNA replication, RNA synthesis, and protein synthesis.

3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin is a nucleoside analog that is used as an activator of phosphoramidite. It can be used as a building block in the synthesis of modified phosphoramidites and it has antiviral, anticancer, and antiinflammatory properties. 3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin is a novel nucleoside analog that can be used to synthesize DNA or RNA. It is also an inhibitor of deoxyribonucleoside kinase, preventing the conversion of deoxyribonucleosides into diphosphate monophosphates.

3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine is a synthetic nucleoside with antiviral properties. It is a monophosphate that can be used to activate other nucleosides. This product has been shown to inhibit human immunodeficiency virus (HIV) reverse transcriptase in vitro and in vivo, as well as the replication of other viruses such as herpes simplex virus (HSV).

5,6-Dihydro-5-azacytidine acetate is a monophosphate nucleoside that is used in the synthesis of DNA and RNA. It is an antiviral agent that inhibits the synthesis of DNA by preventing the conversion of deoxyribonucleotides to diphosphates. 5,6-Dihydro-5-azacytidine acetate has been found to have anticancer properties and is used in cancer treatment. This chemical also has a high purity and quality, making it a suitable reagent for use in phosphoramidite coupling reactions for oligonucleotide synthesis. 5,6-Dihydro-5-azacytidine acetate has been shown to be active against a variety of human tumor cell lines, including leukemia cells.

6-Chloro-9-(5-o-dimethoxytrityl-β-D-2-deoxyribofuranosyl)purine is a phosphoramidite. It is used as an antiviral agent and has been shown to be effective against HIV, herpes zoster, and other viruses. 6-Chloro-9-(5-o-dimethoxytrityl)-2'-deoxyribofuranosyl)purine is a novel nucleotide derivative that inhibits the replication of RNA and DNA by inhibiting the synthesis of viral nucleic acids. This compound can also be used for the treatment of cancer cells.

2'-O-Methyladenosine (2'-OMeA) is a nucleoside that is a low-energy analog of adenosine. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. 2'-OMeA has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). 2'-OMeA inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides. The chemical structures of 2'-OMeA are similar to those found in fatty acids and can be detected using chemical ionization mass spectroscopy. The sequence for 2'-OMeA was determined through sequencing methods including NMR spectroscopy and nuclear magnetic resonance data analysis.

2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt is a circularization agent that can be used in the efficient method for the synthesis of DNA. It inhibits the growth of bacteria by binding to their DNA and preventing transcription. 2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt has shown inhibitory effects against tuberculosis and other infectious diseases, including diphtheria, tetanus, typhoid fever, and malaria. This drug also prevents the replication of viral RNA. The inhibition occurs through an analog mechanism at the level of nucleic acid synthesis or polymerase chain reaction (PCR). The thiophosphate group is cleaved from the triphosphate moiety in the presence of metal ions such as Zn2+, Mg2+, Mn2+, or Ca2+. The active form is enzymatically hydrolyzed by covalent enzyme activity to

5'-Amino-5'-deoxyadenosine hydrochloride (5'-ADeA) is a nucleotide that is synthesized from ribose 5-phosphate and adenosine monophosphate. It has been shown to have potential as a biomarker for skin cancer. The synthesis of 5'-ADeA is catalyzed by the enzyme caffeic acid 4-monooxygenase, which converts caffeic acid into 5'-ADeA. This reaction requires molecular oxygen, NADPH, and iron ions. The activity of this enzyme can be inhibited by sodium carbonate or basic fibroblast growth factor (bFGF). This drug has been shown to have anti-inflammatory effects in vivo.

4-Thiouridine-5'-triphosphate sodium salt - aqueous solution (4TUTP) is an analog of uridine and can be used as a template for the synthesis of single-stranded DNA. 4TUTP has been shown to have a high affinity for dsDNA, allowing it to form a ternary complex with DNA polymerase and single-stranded DNA template. 4TUTP can also be used to prepare samples for profiling experiments or other molecular studies. It is reactive, so should be handled with caution in order to avoid unwanted crosslinking. 4TUTP may also be used in chloroplast research.

N4-Benzoyl-2'-deoxy-5'-O-levulinoylcytidine is a modified nucleoside that is synthesized from 2,4-dichloroacetophenone and cytidine. It has been shown to be an activator of the ribonucleotide reductase enzyme, which converts deoxyribonucleosides into their corresponding ribonucleotides. This drug is used in cancer therapy as well as antiviral and antiretroviral therapy. N4-Benzoyl-2'-deoxy-5'-O-levulinoylcytidine is also being investigated for use in treating other diseases such as malaria and AIDS.

3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine is a nucleoside monophosphate with antiviral activity. It is a synthetic nucleoside that has been modified to be resistant to degradation by ribonucleases. 3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine inhibits the synthesis of DNA, RNA and protein and is used for treatment of cancer. This drug is not active against other types of viruses such as herpes simplex virus or cytomegalovirus.

Uridine 5'-triphosphate disodium salt is a supramolecular complex that binds to gold nanoparticles. The binding of uridine 5'-triphosphate disodium salt to gold nanoparticles can be used for the detection of metal ions through the photometric method. Uridine 5'-triphosphate disodium salt has been shown to inhibit the glutathione-dependent reduction of vitamin B12, which is a key step in methionine synthesis and folate metabolism. This inhibition may lead to a decrease in protein synthesis, ATP production, and cell division.

2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a monophosphate nucleoside that is used as an antiviral and anticancer drug. It inhibits the synthesis of DNA, RNA, and proteins by acting as a chain terminator. 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine inhibits viral replication by blocking the formation of viral DNA. This compound is also used for the treatment of cancerous cells. 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine has shown to be effective against leukemia cells in culture. 2'-Deoxy -2' -fluoro N4 benzoyl 5 methyl cytidine has been synthesized with high purity and is available in a variety of modifications including phosphoramidites and deoxyribonucleosides.

Amidite designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.

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6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine is a novel nucleoside analog that has been modified to include a 2'-C methyl group at the 5' position. This modification prevents the formation of an undesired phosphodiester linkage between the nucleotide and ribonucleotide moieties, which can lead to degradation of the drug. The purine base is attached at the 3' position, which is important for its antiviral activity. 6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methylbDribofuranosyl)purine is active against DNA viruses and has anticancer properties.

2'-Deoxyguanosine 3'-O-L-valinyl ester is a synthetic nucleoside obtained from 2'-deoxyguanosine and valine. It has antiviral activity against DNA viruses, such as herpes simplex virus and vaccinia virus, and anticancer activity. 2'-Deoxyguanosine 3'-O-L-valinyl ester is an analog of guanosine that has been modified to contain an L-valyl group at the 3' position. This modification increases the stability of this nucleoside in aqueous solutions and provides potent antiviral and anticancer activity.

2'/3'-(N-Methylanthraniloyl)-adenosine-5'-triphosphate triethylammonium salt is a phosphoramidite, deoxyribonucleoside that is active as an antiviral. It inhibits the production of viral DNA and RNA by binding to the polymerase enzyme that copies the viral genome. This drug has been shown to be effective in vitro and in vivo against a wide range of viruses, including HIV, herpes simplex virus type 1 and 2, cytomegalovirus, varicella zoster virus, influenza A virus, and poliovirus. It also has anticancer activity by inhibiting cell proliferation.

2-Amino-4-(4-methoxyphenyl)pyrimidine (AMP) is a synthetic nucleoside analog. It has antiviral activity and is used for the treatment of hepatitis B virus infection. AMP inhibits viral DNA polymerase and prevents the synthesis of viral DNA and RNA. It has been modified to include a methoxy group at the 4 position, which provides additional stability against the enzyme ribonuclease. AMP is also an activator of ribonucleotide reductase and can be used as a substrate to synthesize deoxyribonucleosides, phosphoramidites, diphosphate, or monophosphate nucleotides for DNA synthesis. AMP has CAS number 99844-02-7 and is available in high purity.

S-adenosyl-L-methionine chloride dihydrochloride is a form of S-adenosyl-L-methionine. It is used as a nutritional supplement and has been shown to increase the production of antibodies in the body. This drug is also used for the treatment of inflammatory diseases, such as rheumatoid arthritis and osteoarthritis, because it inhibits cyclooxygenase enzymes. S-adenosyl-L-methionine chloride dihydrochloride binds to the response element on DNA that regulates gene expression and inhibits polymerase chain reactions by blocking the binding of nucleic acids to their complementary strands. The mechanism of action of this drug has not been established but may be related to its ability to inhibit nuclear DNA transcription or cell proliferation by affecting camp concentration.

5'-O-p-Anisoyl-2'-deoxyuridine is a novel activator that is an analogue of pyrimidine and has been synthesized for the first time. It belongs to the group of nucleosides and has been modified chemically. This compound can be used as a pharmaceutical drug for the treatment of cancer or viral infections.

2',3'-Stannyluridine is a novel modified ribonucleoside. It is synthesized by the condensation of 2'-deoxyuridine and 3'-hydroxy-2-methylpropiophenone. This product has been shown to have anticancer and antiviral activities. 2',3'-Stannyluridine inhibits the synthesis of DNA, RNA, and protein in cells by binding to the ribonucleotide reductase enzyme. It also has an effect on phosphoramidite synthesis, which is an important step in DNA replication. The CAS number for this product is 57824-03-1.

L-5-methyluridine is a nucleoside that is used as a building block in the synthesis of oligonucleotides. It contains one ribose sugar and one deoxyribose sugar, linked to the base adenine by a phosphate group. L-5-methyluridine can be synthesized from 5-chloro-2'-deoxyadenosine, hypoxanthine, and ammonium chloride. The synthesis starts with condensation reactions between the two sugar molecules to form an intermediate called a nucleoside. This is followed by alkylation of the base and then oxidation of the sugar group to form anomeric esters. The last step involves hydrolysis of the acyloxy ester, which yields L-5-methyluridine after acidification.

Cytidine based prodrug with gemcitabine is a nucleoside analog that has antiviral and anticancer properties. It is a modified cytidine-based prodrug with gemcitabine which is an anticancer drug. Cytidine based prodrug with gemcitabine inhibits viral DNA synthesis by competitively inhibiting the incorporation of deoxycytidine monophosphate into the viral DNA chain. The prodrug also inhibits the proliferation of cancer cells by interfering with DNA synthesis, which leads to cell death.

Adenosine 5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. It is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.

2-Amino-2'-deoxy-2'-fluoroadenosine is a modified nucleoside. Fluorination modifications can make molecules have increased resistance to enzymatic degradation, which has useful applications in drug development. The extra amino group could also enhance binding properties or alter biological activity.

N6-Acetyl-2',3',5'-tri-O-acetyl-8-hydroxyadenosine is a modified nucleoside that is used in the synthesis of oligonucleotides. It is an activator with antiviral and anticancer properties, as well as various other biological activities. The CAS number for this product is 91359-02-2. The purity of this product ranges from 99% to 100%. This chemical has not been previously synthesized and has not been modified by any substituents or moieties.

N3-Cyanoethyl-5’-O-DMT-2’-O-methyluridine is a nucleoside that is synthesized from 5'-O-DMT-2’-O-methyluridine. It has antiviral and anticancer properties, as well as an inhibitory effect on DNA synthesis. N3-Cyanoethyl-5’-O-DMT-2’-O methyluridine is a novel nucleoside with DMT and methylated uracil at the 3' position of the sugar moiety. Synthesis may be achieved by using phosphoramidites or modified nucleosides such as N3-(cyanoethyl)-5'-0-(dimethoxytrityl)thymidine. This product meets high purity standards, with a CAS number of 68719-77-8.

4-Chloro-7-(2C-methyl-3,5-bis-O-(4-methylbenzoyl)-b-D ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a monophosphate nucleotide analog. It is structurally related to the natural nucleoside 2′,3′ dideoxyadenosine. It can be used as an antiviral agent and has also been shown to have possible use in the treatment of HIV infections. 4C7DPP is a novel compound that is synthesized from phosphoramidites and activated with a novel activator. The purity of this compound is high and the quality is very good. CAS No. 1338072-45-9

GDP-D-mannose disodium salt from Saccharomyces Cerevisiae is a nucleoside that is synthetically modified. It has antiviral and anticancer activities, as well as the ability to activate DNA synthesis. This product is suitable for use as a novel activator of DNA and RNA synthesis, in the treatment of viral infections, or cancer.

3’-Deoxy-3’-fluoro-N6-methyladenosine is a synthetic nucleoside analog with antiviral and anticancer properties. 3’-Deoxy-3’-fluoro-N6-methyladenosine is an activator of the telomerase enzyme, which may lead to cancer cell death. It has also been shown to inhibit DNA synthesis in human cells. 3’-Deoxy-3’-fluoro-N6-methyladenosine is a novel nucleoside analog that has not been used clinically before, but has shown promising results in the lab.

2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-trifluoromethyluridine is a nucleoside that has been synthesized from uridine. It is used in the synthesis of deoxyribonucleosides and ribonucleosides. This product can be used for the treatment of cancer and antiviral purposes.