
Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Products of "Nucleosides"
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7-Deaza-2’-C-methylinosine
7-Deaza-2’-C-methylinosine is an antiviral agent that inhibits the replication of DNA or RNA. It is a nucleoside analog that can be phosphorylated to form a diphosphate or monophosphate. 7-Deaza-2’-C-methylinosine has been shown to have anticancer effects in vitro and in vivo, as well as inhibit the proliferation of cancer cells. This agent also has novel properties due to the presence of the methyl group at position 2’ on the deoxyribose ring.Formula:C11H11N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:281.22 g/mol1,N6-Ethenoadenosine-5'-monophosphate sodium salt
CAS:1,N6-Ethenoadenosine-5'-monophosphate sodium salt is a synthetic nucleoside analog. It serves as an antiviral and anticancer agent by inhibiting viral DNA polymerase and tumor cell proliferation. This drug has been shown to be effective in animal models of cancer. 1,N6-Ethenoadenosine-5'-monophosphate sodium salt also inhibits the enzyme ribonucleotide reductase, which is needed for deoxyribonucleotide synthesis. 1,N6-Ethenoadenosine-5'-monophosphate sodium salt is chemically related to adenosine monophosphate (AMP). However, it is not active against AMP phosphohydrolases that are found in bacteria and some protozoa.Formula:C12H14N5O7PPurity:Min. 95%Molecular weight:371.24 g/molN4-Propanoylcytidine
CAS:N4-Propanoylcytidine is a modified nucleoside which can be used as an antiviral agent, anticancer agent and activator. It activates the immune system by stimulating the production of interferon, resulting in the inhibition of viral replication. N4-Propanoylcytidine has also been shown to inhibit the proliferation of cancer cells and induce apoptosis. This compound has a novel chemical structure that is not found in natural nucleosides.Purity:Min. 95%5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)uridine
CAS:5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)uridine is a novel nucleoside analog that is phosphorylated by DNA kinase to form the corresponding monophosphate. This compound inhibits viral replication and has been shown to be effective against some types of cancer cells, with little toxicity to normal cells. 5’-Azido-5’-deoxy-2’-O-(2-methoxyethyl)uridine is modified at the 2′ position in the sugar moiety, which prevents its incorporation into DNA or RNA.Purity:Min. 95%2',3'-Dideoxyuridine
CAS:Research tool for anti-viral and anti-cancer studiesFormula:C9H12N2O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:212.21 g/mol5-Bromo-2'-deoxyuridine
CAS:5-Bromo-2'-deoxyuridine (5-BrDU) is a nitrate reductase inhibitor that prevents the reduction of nitrate to nitrite by inhibiting the enzyme nitrate reductase. It is a genotoxic agent that has been shown to cause DNA damage and cell death in vitro. 5-BrDU has been shown to induce preconditioning in vivo, reducing neuronal injury after ischemia. This drug also binds to NMDA receptors and may be useful as a model system for studying neurodegenerative diseases such as Alzheimer's disease. 5-BrDU has been shown to inhibit the polymerase chain reaction in wild-type strains of bacteria, but not in strains with a mutation in their DNA gyrase genes.Formula:C9H11BrN2O5Purity:Min. 99 Area-%Color and Shape:White Off-White PowderMolecular weight:307.1 g/molN2-Benzoylguanosine
CAS:N2-Benzoylguanosine is a nucleotide derivative that is formed by the acetylation of guanosine. It has been shown to act as a buffer in alkaline solutions and isomerizes to its n-oxide form when heated. N2-Benzoylguanosine reacts with peroxides such as hydrogen peroxide, glyoxal, and organic peroxides, forming hydroperoxide intermediates that can be converted into other products. The acidic hydrolysis of N2-benzoylguanosine yields the corresponding 6-benzoyladenosines. It has been shown to enhance the activity of uridine in inhibiting bacterial growth, while also acting as an inhibitor of viral RNA synthesis. This compound also reacts with nitrous acid to form an n6-benzoyladenosine derivative that inhibits the formation of RNA chains during transcription.Formula:C17H17N5O6Purity:Min. 95%Color and Shape:White to beige solid.Molecular weight:387.35 g/molPyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione
CAS:Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione is a small molecule that can function as a transcriptional activator or repressor by binding to DNA. This drug has been shown to upregulate the expression of genes that are involved in the immune system and inflammation.Purity:Min. 95%5-Vinylcytidine
CAS:Please enquire for more information about 5-Vinylcytidine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%2'-Deoxy-N4-methylcytidine 5'-triphosphate lithium salt - 100 mM aqueous solution
2'-Deoxy-N4-methylcytidine 5'-triphosphate lithium salt is a replication inhibitor that inhibits the synthesis of DNA. The drug binds to the replicase, which prevents the elongation of the single-stranded DNA chain by blocking the polymerase and terminating transcription. 2'-Deoxy-N4-methylcytidine 5'-triphosphate lithium salt can be used for research purposes in nucleic acid research, including single-stranded DNA, RNA, or protein synthesis. It has been shown to be effective in preventing artifacts during polymerase chain reactions.Formula:C10H18N3O13P3Purity:Min. 95%Molecular weight:481.18 g/mol3-Deaza-3'-O-methyluridine
Please enquire for more information about 3-Deaza-3'-O-methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C11H15NO6Purity:Min. 95%Molecular weight:257.24 g/mol2'-Deoxycytidine, 99+%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C9H13N3O4Purity:99+%Color and Shape:White, Crystalline powderMolecular weight:227.222'-Chloro-2'-deoxycytidine
CAS:2'-Chloro-2'-deoxycytidine is a synthetic nucleoside analog. It is a modified deoxycytidine with a chlorine atom at the 2'-position of the deoxyribose sugar. This molecule can be used in research applicationsFormula:C9H12ClN3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:261.66 g/molN4-Anisoyl-2'-deoxycytidine
CAS:N4-Anisoyl-2'-deoxycytidine is a nucleoside that contains a long chain of four carbon atoms. It is the cyclic form of N4-anisoyl-2'-deoxyadenosine. This compound has been shown to be synthesized in yields of up to 71% using acid anhydrides and diamino compounds. N4-Anisoyl-2'-deoxycytidine is a bifunctional reagent that can be used as a starting material for the synthesis of oligodeoxyribonucleotides. The compound has also been shown to function as an effective inhibitor of DNA synthesis, which may lead to anti-cancer effects.Formula:C17H19N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:361.35 g/molN6,7-Dimethyldeoxyadenosine
N6,7-Dimethyldeoxyadenosine is a nucleoside with antiviral and anticancer properties. It is a modified DNA monophosphate with the chemical formula C8H16N2O6P. N6,7-dimethyldeoxyadenosine has been shown to inhibit the replication of HIV and herpes simplex virus type 1 (HSV-1) in vitro. This compound also inhibits the growth of cancer cells in culture and has been suggested as an anticancer therapeutic agent.Purity:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite is a nucleoside that is synthesized by the modification of uridine with a 2'-O-tert-butyldimethylsilyl group, followed by coupling with 5'-O-DMT. This nucleoside is used in the synthesis of oligonucleotides for use in gene expression and viral replication studies. It is also used as a building block for the synthesis of other nucleosides. The synthesized product has been shown to be stable and can be stored at room temperature for up to two years without degradation. This product is also compatible with a variety of functionalities, such as acetonitrile and levulinyl.Formula:C45H61N4O9PSiPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:861.04 g/mol5-Fluorouridine-5'-diphosphate sodium
CAS:5-Fluorouridine-5'-diphosphate sodium salt is a nucleoside analog that inhibits the synthesis of RNA and DNA. It is used to treat cancer, as well as opportunistic infections, such as cryptococcal disease. 5-Fluorouridine-5'-diphosphate sodium salt binds to the enzyme thymidylate synthase and prevents it from synthesizing dTMP, which is needed for DNA synthesis. This drug also has been shown to be effective against monoclonal antibodies in mice with cancer. 5-Fluorouridine-5'-diphosphate sodium salt may also be useful in gene therapy for cancer treatment. This drug can be taken up by cells where it is converted into uracil, which inhibits protein synthesis by competing with the natural substrate tRNA for binding sites on ribosomes.Formula:C9H13FN2O12P2•NaxPurity:Min. 95%Color and Shape:PowderMolecular weight:423.16 g/mol2',3'-Dideoxyadenosine-5'-triphosphate lithium salt
CAS:2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a nucleoside for use in research applicationsFormula:C10H16N5O11P3·xLiPurity:Min. 95%Color and Shape:Clear liquid.Molecular weight:475.18 g/mol9-(β-D-Arabinofuranosyl)adenine 5'-monophosphate
CAS:9-(β-D-Arabinofuranosyl)adenine 5'-monophosphate (Ara-AMP) is a prodrug that is converted to adenine arabinoside in vivo. It is used as an antiviral agent for the prevention of hepatitis B and C. Ara-AMP inhibits viral DNA synthesis by acting as a competitive inhibitor of adenosine triphosphate, which is required for viral DNA polymerase activity. Ara-AMP also has antiviral properties against some RNA viruses, such as HIV and influenza virus. Ara-AMP can be administered orally or by injection, making it suitable for use in children who are unable to take oral medication.Formula:C10H14N5O7PPurity:Min. 95%Color and Shape:White PowderMolecular weight:347.22 g/molN6-Benzoyl-2'-deoxyadenosine
CAS:N6-Benzoyl-2'-deoxyadenosine (BADA) is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. BADA binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. BADA has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.Formula:C17H17N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:355.35 g/molCordycepin-13C5
CAS:Controlled ProductFormula:C513C5H13N5O3Color and Shape:NeatMolecular weight:256.211-(8-Phosphonooctyl)-7-deazaxanthine ammonium salt
CAS:Ribonucleosides are a group of compounds that are similar to the nucleosides, but contain ribose as the sugar component. Ribonucleosides have been shown to have anticancer properties in-vitro and in-vivo. The compound 1-(8-Phosphonooctyl)-7-deazaxanthine ammonium salt is a novel monophosphate nucleotide with antiviral and antimalarial activities. It has also been shown to be an activator of DNA synthesis, which may lead to its use as a therapeutic agent for cancers or viral infections. This compound has a high purity and quality level, and is available at CAS No. 265322-84-7.br>Purity:Min. 95%2',3'-O-Isopropylideneuridine
CAS:2′,3′-O-Isopropylideneuridine serves as a key intermediate in the chemical synthesis of N-benzoyl uridine derivatives and N3-substituted 2′,3′-O-isopropylideneuridines, which exhibit central nervous system (CNS) depressant propertiesFormula:C12H16N2O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:284.27 g/mol[U-13C10, U-15N2]-Labelled thymidine
Thymidine is a nucleoside that is a component of DNA and RNA. It is also the precursor for thymine, the DNA base in which the thymine ring is derived from. Thymidine has been shown to be an activator of DNA synthesis, as well as being anticancer and antiviral.Purity:Min. 95%Cytidyl-3'-5'-adenosine ammonium salt
Please enquire for more information about Cytidyl-3'-5'-adenosine ammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite is a monophosphate nucleoside analog that is synthesized in an acetylated form. It is an activator of DNA synthesis, and as such, has anticancer activity. This compound also inhibits the replication of DNA viruses and has antiviral activity against influenza virus. N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite has been shown to be effective in the prevention of HIV infection in vitro.Formula:C41H49FN5O8PPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:789.83 g/mol2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite
The 2'-deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite is a high quality and novel nucleoside. This compound is used as an anticancer drug, antiviral agent, and in the synthesis of DNA. It has a modified structure with two acetyl groups at the 2' position, which increases its stability to hydrolysis and reduces its susceptibility to enzymatic degradation. The phosphoramidite group is synthesized by reacting the 5'-O-levulinoylguanosine with diethylcyanophosphate, followed by reaction with ammonia in anhydrous pyridine.Formula:C28H42N7O8PPurity:Min. 95%Molecular weight:635.65 g/mol5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite
CAS:5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite is a novel nucleoside phosphoramidite. It is an activator of DNA polymerase for the synthesis of diphosphate analogues of ribonucleosides and deoxyribonucleosides. This compound has been used in the synthesis of antiviral and anticancer agents, as well as in research on the development of new antiviral drugs.Purity:Min. 95%9-(3'-O-Deoxy-3'-fluoro-b-D-xylofuranosyl)adenine
9-(3'-O-Deoxy-3'-fluoro-b-D-xylofuranosyl)adenine is a nucleoside that is synthesized by modifying the ribonucleosides. It has been found to be an activator of a novel anticancer drug, which has shown promising results in preclinical studies. 9-(3'-O-Deoxy-3'-fluoro-b-D-xylofuranosyl)adenine has been shown to activate the deoxyribonucleoside phosphorylase (DNP), which acts on nucleotides and converts them into their corresponding monophosphate or diphosphate forms. This activation process is important for DNA metabolism and replication.Purity:Min. 95%Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a monoclonal antibody. It is used in the diagnosis of lung cancer. The antibody binds to markers present on the tumor cells and can be detected by immunohistochemistry (IHC) or immunofluorescence (IF). The antibody may also be used to identify submucosal tumors that are not palpable.Formula:C22H34N5O17P3S·xLiPurity:Min. 95%Molecular weight:765.52 g/mol2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine-3’-(4-nitrophenoxyl)butanedioate
2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine-3’-(4-nitrophenoxyl)butanedioate is a novel antiviral drug that has been synthesized by coupling diphosphate and monophosphate nucleosides to an antiviral agent. The synthesis of this product is done through the use of activated 2,4,6,-trichlorobenzoyl chloride as a coupling agent. This product can be used in the treatment of cancer cells.Purity:Min. 95%6-Chloro-N4-methyl-4,5-pyrimidinediamine
CAS:6-Chloro-N4-methyl-4,5-pyrimidinediamine is a monophosphate nucleotide. It is a synthetic compound that is used as an antiviral agent and as an anticancer drug. The compound has been shown to inhibit the replication of DNA by inhibiting the activity of DNA polymerase. 6-Chloro-N4-methyl-4,5-pyrimidinediamine also inhibits the synthesis of RNA by inhibiting the enzyme RNA polymerase. As a result, this compound is toxic to cells because it prevents protein production and replication. This product has high purity and high quality. It can be used in phosphoramidites, which are necessary for the production of DNA and RNA in cells.Purity:Min. 95%9-β-D-Arabinofuranosylguanine
CAS:Formula:C10H13N5O5Purity:98%Color and Shape:SolidMolecular weight:283.24072’,3’-Dideoxy-5-fluorocytidine
CAS:2’,3’-Dideoxy-5-fluorocytidine is a nucleoside analog that inhibits the growth of tumor cells in animals. It has been shown to inhibit the replication of hepatitis B virus and HIV without affecting normal cell division. 2′,3′-Dideoxy-5-fluorocytidine also has potent antitumor activity against human hematopoietic cells and induces apoptosis.Formula:C9H12FN3O3Purity:Min. 95%Molecular weight:229.21 g/molN4-Acetyl-2'-O-acetyl-5'-O-DMT-arabinosyl cytosine 3'-CE phosphoramidite
N4-Acetyl-2'-O-acetyl-5'-O-DMT-arabinosyl cytosine 3'-CE phosphoramidite is a prodrug that is activated by intracellular enzymes. It has been shown to be an immunostimulatory agent, which modulates the immune system for the treatment of cancer and autoimmune disorders. N4-Acetyl-2'-O-acetyl-5'-O-DMT-arabinosyl cytosine 3'-CE phosphoramidite can also act as a ligand for various cell surface receptors and transporters, including CD28, interleukin 2 receptor alpha chain, CD40, CD84, and MHC class II. The compound has been shown to inhibit tumor cells in culture and induces apoptosis in these cells.Purity:Min. 95%Thymidine 5'- triphosphate-3'-monophosphate
CAS:Thymidine 5'-triphosphate-3'-monophosphate is a nucleoside that is used in the synthesis of DNA. It is an activator of anticancer drugs, and has been shown to have antiviral properties. Thymidine 5'-triphosphate-3'-monophosphate can be used for the treatment of viral diseases such as herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and human immunodeficiency virus (HIV) infection. This nucleoside also plays a role in the prevention of tumor growth and metastasis because it inhibits DNA synthesis.Formula:C10H18N2O17P4Purity:Min. 95%Molecular weight:562.15 g/molVidarabine
CAS:Formula:C10H13N5O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:267.25Cytidine 5'-diphosphoglycerol disodium salt
CAS:Cytidine 5'-diphosphoglycerol disodium salt is a modified nucleotide that belongs to the group of phosphoramidites. It is a cytidine derivative with a 2-hydroxymethylene bridge, which makes it resistant to degradation by cytidine deaminase and therefore enhances its anticancer activity. Cytidine 5'-diphosphoglycerol disodium salt has been shown to inhibit the growth of cancer cells in vitro and in vivo models, as well as inhibit viral replication. Cytidine 5'-diphosphoglycerol disodium salt is stable at high temperatures and can be used for activation of DNA synthesis in vitro. This product has not been tested on animals or humans and should not be taken internally.Formula:C12H19N3Na2O13P2Purity:Min. 95%Molecular weight:521.22 g/mol2-Methylthio-N6-isopentenyladenosine
CAS:A nucleoside analogue of adenosine that arises from post-transcriptional modification. In humans, this is mediated by the enzyme CDK5RAP1 in mitochondrial transfer RNA (tRNA) at amino acid 37. Deficiency for this modification, for example due to CDK5RAP1 deficiency, leads to impaired mitochondrial protein synthesis. This has implications for mitochondrial diseases, as well as cancer, type II diabetes and vitiligo. Synthetic ms2i6A can be used to raise monoclonal antibodies against this nucleotide in vivo.Formula:C16H23N5O4SPurity:Min. 95%Color and Shape:White PowderMolecular weight:381.45 g/mol2'-Deoxy-6-thioguanosine
CAS:2'-Deoxy-6-thioguanosine is a purine nucleoside analog that inhibits the activation of transcription factors such as nuclear factor kappa-B (NF-κB) and activator protein 1 (AP-1). It also inhibits the synthesis of proinflammatory cytokines, such as IL-1β, IL-6, and TNFα. The matrix effect is an important factor in the prevention of tumor progression. 2'-Deoxy-6-thioguanosine has been shown to inhibit cell proliferation and induce apoptosis in squamous cell carcinoma cells by modulating the expression of HLA class II molecules on tumors. It also prevents invasion by blocking matrix metalloproteinase activity. 2'-Deoxy-6-thioguanosine has been found to be effective against bowel diseases such as ulcerative colitis and Crohn's disease, as well as infectious diseases such as HIV/AIDS.Formula:C10H13N5O3SPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:283.31 g/mol2'-Deoxy-5-fluoro-N-methylcytidine
CAS:2'-Deoxy-5-fluoro-N-methylcytidine is a phosphoramidite that belongs to the group of deoxyribonucleosides. It is used as an antiviral agent, with high purity and high quality. 2'-Deoxy-5-fluoro-N-methylcytidine has been shown to inhibit the growth of cancer cells and is also a novel nucleoside with anticancer activity.Formula:C10H14FN3O4Purity:Min. 95%Molecular weight:259.23 g/mol3'-Deoxy-3'-fluorothymidine-5'-triphosphate sodium salt
3'-Deoxy-3'-fluorothymidine-5'-triphosphate sodium salt (3'-DFP) is a modified nucleoside that acts as an antiviral and anticancer drug. It is a monophosphate derivative of thymidine, which is converted to diphosphate by the enzyme thymidylate kinase. 3'-DFP inhibits DNA synthesis by preventing the incorporation of deoxyribonucleotides into DNA. 3'-DFP can also be used as a building block in the synthesis of other nucleosides such as cytidine 5′-triphosphate, uridine 5′-triphosphate, and adenosine 5′-triphosphate. 3'-DFP is active against herpesviruses including Epstein-Barr virus, cytomegalovirus, and varicella zoster virus. It has also been shown to inhibit cancer cell proliferation when used at high doses.Purity:Min. 95%3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine
CAS:Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%5-Chloro-1-(b-D-arabinofuranosyl)cytidine
CAS:5-Chloro-1-(b-D-arabinofuranosyl)cytidine is a monophosphate that is used as a precursor in the synthesis of antiviral and anticancer drugs. 5-Chloro-1-(b-D-arabinofuranosyl)cytidine is a synthetic nucleoside that can be activated by phosphorylation to form nucleosides and diphosphates, which are used in DNA synthesis. This drug also has anticancer properties, which have been demonstrated in animal models. It has been shown to inhibit the growth of leukemia cells by inhibiting the proliferation of cells in culture.Formula:C9H12CIN3O5Purity:Min. 95%Molecular weight:277.66 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol
1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is an activator that can be used in the synthesis of DNA and RNA. It is a novel compound with antiviral properties and anticancer effects. It has been shown to have high purity and quality. This activator is a phosphoramidite that can be used in the synthesis of DNA or RNA and has been modified to have antiviral properties. It is synthesized using deoxyribonucleosides as starting materials, which are obtained from natural sources such as yeast extract or tryptophan.Formula:C22H25N5O5Purity:Min. 95%Molecular weight:439.48 g/molL-Inosine
CAS:L-Inosine is a purine nucleoside that is found in plants and animals. It is an intermediate in the pentose phosphate pathway and can be synthesized from the amino acid L-lysine. L-Inosine has been shown to inhibit the growth of trichomonas vaginalis and giardia, but not uninfected human erythrocytes. The mechanism of action of L-Inosine is not well understood, but it may have a role in transporting adenosine into cells. The oral bioavailability of L-Inosine is low due to its rapid conversion to l-adenosine by nonsaturable enzymes. L-Inosine does not appear to be a substrate for transport across mammalian cells, but it does act as a competitive inhibitor for glucose transport.Formula:C10H12N4O5Purity:Min. 95%Color and Shape:Off-White SolidMolecular weight:268.23 g/molIMP + GMP
IMP + GMP is a DNA synthesis activator that can be used to synthesize DNA, RNA, and oligonucleotides. It is modified to have antiviral and anticancer properties. IMP + GMP has been shown to have antiviral activity against HIV-1 and inhibits the replication of the virus in human cells. The drug also has anticancer effects against certain types of cancerous cells. IMP + GMP is synthesized by modifying natural nucleosides with phosphoramidite chemistry, which allows it to be easily incorporated into many diverse synthetic pathways. IMP + GMP is highly purified and can be purchased at high quality for research purposes.Purity:Min. 95%Guanosine 2',3'-cyclic monophosphate sodium
CAS:Guanosine 2',3'-cyclic monophosphate sodium is a novel antiviral agent that has been shown to be effective against HIV, herpesviruses, and vaccinia virus. It is an activator of guanosine 3'-5' cyclic monophosphate (cGMP) and can be used as a substitute for the nucleoside guanosine 5'-triphosphate (GTP). Guanosine 2',3'-cyclic monophosphate sodium inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase and DNA polymerase. This drug also has anticancer properties, which may be due to its ability to inhibit the production of tumor necrosis factor-α (TNF-α) in mice with lung cancer.Formula:C10H11N5NaO7PPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:367.19 g/mol7-Deaza-2'-deoxyxanthosine
CAS:7-Deaza-2'-deoxyxanthosine is an oligodeoxynucleotide that is a substrate for the enzyme dUTPase. The allyl group on 7-deaza-2'-deoxyxanthosine is used to attach it to the 3' end of DNA, where it acts as a competitive inhibitor of RNA synthesis. The ethyl group at the end of the molecule is used to attach it to the 5' end of DNA, where it inhibits transcription and replication by binding with RNA polymerase. 7-Deaza-2'-deoxyxanthosine has been shown to be effective in preventing stenosis following coronary bypass surgery, as well as in treating heart disease by reducing levels of xanthosine.Formula:C11H13N3O5Purity:Min. 95%Color and Shape:Beige PowderMolecular weight:267.24 g/mol2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt is an antibacterial agent with a potent antibacterial activity. It has been shown to be active against Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis. It also inhibits the synthesis of uronic acid and butyric acid, which are components of the bacterial cell wall. In addition, 2'-deoxy-2'-fluorouridine-5'-triphosphate sodium salt is able to inhibit nucleotidylyltransferase, which is an enzyme involved in the biosynthesis of fatty acids in bacteria.Formula:C9H14FN2O14P3·NaPurity:Min. 95%Molecular weight:509.12 g/molThymidylyl-3'-5'-thymidine ammonium
CAS:Thymidylyl-3'-5'-thymidine ammonium is a cytotoxic drug that belongs to the class of thymidylate synthase inhibitors. It inhibits enzymes responsible for DNA synthesis and repair by binding to the active site of these enzymes and forming covalent bonds with amino acid residues. Thymidylyl-3'-5'-thymidine ammonium can be used as a therapeutic agent in radiation therapy because it is more effective than other drugs at inhibiting cell growth. Thymidylyl-3'-5'-thymidine ammonium has been shown to inhibit the activity of carcinogenic compounds, such as benzo[a]pyrene and benzene, in a model system. Thymidylyl-3'-5'-thymidine ammonium also has the ability to form covalent bonds with dna duplexes and change their conformational properties.Formula:C20H27N4O12P·NH3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:563.45 g/molO6-Diphenylcarbonyl-N2-isobutyryl-1-(5'-O-DMT-b-D-arabinofuranosyl) guanine
O6-Diphenylcarbonyl-N2-isobutyryl-1-(5'-O-DMT-b-D-arabinofuranosyl) guanine is a synthetic nucleoside. It is an activator of antiviral, anticancer, and antimalarial agents. O6-Diphenylcarbonylguanine has been shown to be effective in the treatment of HIV patients. It also inhibits the replication of herpes simplex virus type 1 (HSV1) and can be used for the treatment of HSV1 encephalitis. O6-Diphenylcarbonylguanine has also been shown to be effective in the treatment of cancer cells that are resistant to chemotherapy drugs such as cisplatin and doxorubicin.Formula:C47H47N5O9Purity:Min. 95%Molecular weight:825.9 g/mol5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:5'-O-DMT-uridine 3'-CE phosphoramidite is a novel, modified and activator nucleoside. It can be used as an antiviral agent or in the synthesis of DNA. 5'-O-DMT-uridine 3'-CE phosphoramidite has been shown to be cytotoxic in vitro to cancer cells.Formula:C39H47N4O9PPurity:Min. 95%Molecular weight:746.79 g/molN4-Benzoyl-5'-O-DMT-5-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-5-methylcytidine is a deoxyribonucleoside that has been modified to make it resistant to nucleases. N4-Benzoyl-5'-O-DMT-5-methylcytidine is an antiviral agent, which inhibits the synthesis of viral DNA by inhibiting the activity of viral DNA polymerase. It also acts as an activator for cellular DNA polymerases and phosphoramidites. The drug can be used in the treatment of HIV and other retroviruses, herpes viruses, and certain types of cancer.Formula:C38H37N3O8Purity:Min. 95%Color and Shape:White SolidMolecular weight:663.73 g/mol5-(Isopentenylaminomethyl)uridine
CAS:5-(Isopentenylaminomethyl)uridine is a modified uridine nucleoside that is used in biochemical research. It is the precursor to 5-amino-2'-deoxyuridine, which is converted to 5-iodo-2'-deoxyuridine. This modified uridine nucleoside can be used as a linker molecule for DNA and RNA ligation reactions and for analysis of biological samples. 5-(Isopentenylaminomethyl)uridine has been shown to inhibit the expression of genes in eukaryotes and prokaryotes. It also has been shown to inhibit the ribosome by binding to the peptidyl transferase center (PTC).Formula:C15H23N3O6Purity:Min. 95%Molecular weight:341.36 g/mol2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine
CAS:2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine is a synthetic nucleoside that has been modified with a tert-butyldimethylsilyl group. This modification is used to improve the efficiency of coupling reactions between nucleosides and phosphoramidites in oligonucleotide synthesis. The 2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl guanosine is also used as a chromophore in spectroscopy experiments and as a ligand in metal coordination chemistry.Formula:C41H51N5O8SiPurity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:769.96 g/mol5'-Chloro-5'-deoxyadenosine
CAS:Adenosine analogFormula:C10H12ClN5O3Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:285.69 g/molAFB-guanine
CAS:AFB-guanine is a purine nucleoside that has been found to be an intermediate in the conversion of adenosine to inosine. The toxicity of AFB-guanine was studied using the model system of rat liver microsomes and human liver. It was observed that AFB-guanine is metabolized by glycosylases, which act on purines and pyrimidines. The glycosylase activity was inhibited by dicoumarol, which results in a decrease in the amount of AFB-guanine that is converted to adenosine triphosphate (ATP). The study also showed that histological analysis revealed degenerative diseases and cancer in mice fed with AFB-guanine, suggesting that this compound may be carcinogenic.Formula:C22H17N5O8Purity:Min. 95%Molecular weight:479.4 g/mol4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid
CAS:4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a novel nucleoside analog that has been shown to have anticancer activity. It has also been found to have antiviral and antitumor activities. 4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a nucleoside analog that is synthesized from monophosphate, diphosphate, and phosphate esters of 2-(methylthio)pyrimidine 5'-carboxylic acid. It is an analogue of the natural nucleoside uridine and has phosphorylase enzyme activity. This agent is cytotoxic against cells in culture by inhibiting DNA synthesis.Formula:C18H22N4O2SPurity:Min. 95%Molecular weight:358.46 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is a novel nucleotide analogue that inhibits the growth of cancer cells by inhibiting DNA synthesis. It has been shown to be cytotoxic against leukemia, lymphoma, and breast cancer cells in vitro. N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is also an antiviral agent and can inhibit HIV replication. This product is supplied as a white solid powder and is soluble in water.Purity:Min. 95%2'-Deoxyguanosine-5'-carboxylic acid
CAS:2'-Deoxyguanosine-5'-carboxylic acid is a synthetic nucleoside that has antiviral and anticancer properties. It is an activator of DNA polymerase, which is used in the synthesis of DNA. 2'-Deoxyguanosine-5'-carboxylic acid also inhibits the activity of ribonucleotide reductase and deoxyribonucleotide reductase, which are enzymes that catalyze the conversion of ribose-5-phosphate to deoxyribose-5-phosphate. This substance also blocks viral replication by inhibiting RNA synthesis in cells infected with HIV or herpes simplex virus type 1.Formula:C10H11N5O5Purity:Min. 95%Molecular weight:281.23 g/molCytidine 3',5'-bisphosphate sodium
CAS:Cytidine 3',5'-bisphosphate sodium is a phospholipid that is found in the cell membrane of gram-positive bacteria. Cytidine 3',5'-bisphosphate sodium has been shown to be produced by the enzyme phosphatidylcholine synthase, which converts phosphatidylethanolamine and cytidine 5'-monophosphate into phosphatidylcholine and cytidine 3',5'-bisphosphate. The presence of this compound in the cell membrane may be an indication of long-term survival and growth under laboratory conditions. It is also present in the ribosomal RNA of type strain organisms.Formula:C9H15N3O11P2•NaxPurity:Min. 95%Molecular weight:403.18 g/molStearoyl coenzyme A free acid hydrate
CAS:Stearoyl coenzyme A free acid hydrate is a natural, non-synthetic lipid molecule that belongs to the group of fatty acids. It is found in the form of a white crystalline powder and has a melting point at approximately 56°C. Stearoyl CoA free acid hydrate is an essential component of cellular metabolism, carrying out reactions such as desaturase, dextran sulfate, and other enzyme activities. Stearoyl CoA free acid hydrate may have therapeutic applications for metabolic disorders and obesity. The enzyme complex that catalyzes the synthesis of stearoyl CoA free acid hydrate in adipocytes is ATP-binding cassette transporter (ABC) A1 and ABCG1, which are members of the superfamily of ATP-binding cassette (ABC) transporters. It also plays a role in regulating immune responses via Toll-like receptor 4 (TLR4).Formula:C39H70N7O17P3S•H2OPurity:Min. 92 Area-%Color and Shape:White PowderMolecular weight:1,052.01 g/mol5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite
This is a phosphoramidite that is used in the synthesis of DNA. The chemical name for this compound is 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine 3'-CE phosphoramidite. This compound has been shown to be an anticancer drug and has high purity, high quality, and novel properties.Formula:C52H62N7O10PPurity:Min. 95%Color and Shape:White PowderMolecular weight:976.09 g/mol2'-Deoxy-N2-DMF-5'-O-tritylguanosine 3'-CE phosphoramidite
2'-Deoxy-N2-DMF-5'-O-tritylguanosine 3'-CE phosphoramidite is a novel phosphoramidite nucleoside of the antiviral agent N2-DMF-5'-O-tritylguanosine, which has been modified to contain a deoxyribonucleoside at the 5' position. The phosphoramidite nucleotide is synthesized by reacting 2'-deoxyadenosine with DMF and 2,4,6-trichlorobenzoyl chloride in an organic solvent such as dichloromethane. It is then purified by recrystallization or chromatography to remove impurities such as DMF, 2,4,6-trichlorobenzoyl chloride, and other non-reacted compounds. This product can be used in the synthesis of oligonucleotides for use in DNA sequencing.Formula:C41H49N8O5PPurity:Min. 95%Molecular weight:764.87 g/mol2',3'-Dideoxyinosine
CAS:Formula:C10H12N4O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:236.23Acetyl hypoxanthine
CAS:Acetyl hypoxanthine is an inorganic compound that has a cyclophosphate group. It can be synthesized from the reaction of acetic acid and 6-chloropurine, which is activated with trifluoroacetic acid and irradiated with ultraviolet light. Acetyl hypoxanthine can then be synthesized by ammonolysis of chloroacetone using ammonia or by chlorinating acetylene with chlorine. The advantages of this compound are its high yield and low cost.Formula:C7H6N4O2Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:178.15 g/molN4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine
CAS:N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a nucleoside analog that is used as an antiviral and anticancer drug. It is also known to be an activator of the immune system. N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to inhibit viral DNA replication, induce apoptosis, and inhibit tumor growth. The drug has shown potential in treating chronic hepatitis B virus infections, some types of cancer, and HIV/AIDS.Formula:C34H37N3O8Purity:Min. 95%Molecular weight:615.67 g/mol1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine
CAS:1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine is a nucleoside that can be used as a reagent in the synthesis of oligodeoxynucleotides. It has been shown to bind to DNA, and it is phosphoramidite monomer for solid phase synthesis of oligodeoxynucleotides. It is also a nonamer, octamer, and dinucleoside. 1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine binds to the receptor protein and has been shown to have efficiencies as high as 45%.Formula:C31H32N2O7Purity:Min. 95%Molecular weight:544.6 g/molN4-Acetyl-5-methylcytidine
CAS:N4-Acetyl-5-methylcytidine is a novel, modified nucleoside with antiviral and anticancer properties. It is an activator of RNA polymerase II and inhibits DNA synthesis by inhibiting the activity of DNA polymerase. N4-Acetyl-5-methylcytidine has been shown to be effective in treating cancers that are sensitive to chemotherapy, such as lymphomas, myelomas, and leukemias. It can be used as a substitute for cytosine in the synthesis of oligonucleotides and phosphoramidites.Purity:Min. 95%2',3'-Dideoxy-5-iodouridine
CAS:2',3'-Dideoxy-5-iodouridine is a synthetic nucleoside analog derived from uridine, one of the natural building blocks of RNA. This molecule has been chemically modified to disrupt the normal processes of DNA and RNA synthesis, making it a candidate for antiviral and anticancer research.Formula:C9H11IN2O4Purity:Min. 95%Color and Shape:PowderMolecular weight:338.1 g/mol4’,5’-Didehydro-2’-O-methyl-5-methyluridine
CAS:4,5-Didehydro-2'-O-methyl-5'-methyluridine (4,5-DdUMP) is a monophosphate nucleoside that has antiviral and anticancer properties. It is an activator of DNA polymerase alpha and can be used to synthesize DNA. 4,5-DdUMP is a precursor to the nucleosides in the synthesis of deoxyribonucleic acid (DNA). This compound also inhibits DNA gyrase and topoisomerase IV. 4,5-DdUMP has been shown to be active against HIV, herpes simplex virus type 1 (HSV1), HSV type 2 (HSV2), human cytomegalovirus (CMV), Epstein Barr virus (EBV), influenza A virus, vesicular stomatitis virus (VSV), mouse leukemia L1210 cells, and human leukemia HL60 cells. It also inhibits proliferation of tumorPurity:Min. 95%NADPH 4Na - min 95%
CAS:Coenzyme and regenerating electron donor in catabolic processesFormula:C21H26N7O17P3·4NaPurity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:833.35 g/mol2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate
CAS:10umol is approx 5mg.2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate is a novel nucleoside phosphorylated on the 5' positionPurity:Min. 95%5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide
CAS:5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide (AICAR) is a high purity novel nucleotide analog that has been shown to be an activator of AMPK. AICAR can act as a substitute for ATP, the molecule that drives cellular energy production. AICAR has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound also inhibits viral RNA replication by competitively binding to the enzyme polymerase, which is essential for viral replication.Formula:C15H20N4O8Purity:Min. 95%Molecular weight:384.34 g/mol3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
CAS:3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine (BUdR) is an antiviral agent that is used in the synthesis of DNA and RNA. BUdR is a modified phosphoramidite that is activated with diphosphate. It has a high quality, high purity, and a novel structure. BUdR has been shown to have anticancer properties as well as inhibitory effects on HIV production in cells.Formula:C16H27N5O4SiPurity:Min. 95%Molecular weight:381.51 g/molN4-Benzoyl-2'-O-methylcytidine
CAS:N4-Benzoyl-2'-O-methylcytidine is a triester of cytidine that is used in various biochemical research applications. It is enzymatically synthesized from cytidine and benzoyl chloride. N4-Benzoyl-2'-O-methylcytidine has been shown to have the same electrophoretic mobility as 5-hydroxyl cytidine, but it does not react with hydroxylamine to produce the corresponding hydroxylated product. This compound has also been used to study nucleic acid structure and function.Formula:C17H19N3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:361.35 g/mol4-Bromo-2-methoxypyrimidine
CAS:4-Bromo-2-methoxypyrimidine is a synthetic compound that is used in the synthesis of other compounds. It reacts with alcohols, boronic acids, and benzyl halides to form heterocycles or pyrimidine compounds. The reaction system is catalytic and chemoselectively. 4-Bromo-2-methoxypyrimidine has been shown to have anticancer activity against various cell lines in vitro. It also possesses an ability to react with aryl boronic acids, such as those found in 2-pyridinones, to form new compounds. This reaction is catalyzed by palladium on carbon or copper chloride in the presence of a base. The new compounds have shown anti-inflammatory and cytotoxic activities against cancer cells.Purity:Min. 95%2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine
CAS:2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine is a novel modified nucleoside. It is a high quality monophosphate that can be used as an activator for DNA synthesis. This compound has shown anticancer activity in various cell lines and has antiviral properties. It can be used as a phosphoramidite for the synthesis of oligonucleotides. 2’,3’,5’-Tri-O-benzoyl-5-difluoromethyluridine is synthesized by using 5'-DMT-2',3',5' -triphosphate as the starting material. The diphosphate is then oxidized to form the corresponding triphosphate (the active form).Formula:C31H24F2N2O9Purity:Min. 95%Molecular weight:606.53 g/mol6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution
CAS:6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution is a modified nucleoside that is used as an activator in the synthesis of DNA and RNA. 6-Methylthioguanosine-5’- triphosphate sodium salt - 10 mM aqueous solution can be used to synthesize ribonucleosides, deoxyribonucleosides and phosphoramidites. It has antiviral properties, which may be due to its ability to inhibit viral polymerase by competitively binding to the enzyme's active site. 6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution also has anticancer effects and is able to induce apoptosis in cancer cells.Formula:C11H18N5O13P3S·xNaPurity:Min. 95%Molecular weight:553.27 g/molN2-(Dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine
CAS:N2-(Dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine is a modified nucleoside that is an activator of DNA, deoxyribonucleosides, and nucleotides. It has been shown to be active against herpesviruses, HIV-1, and cancer cells in vitro. N2-(Dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine has also been shown to have antiviral activity against influenza A virus. This compound belongs to the class of novel anticancer agents that inhibit the proliferation of cancer cells by interfering with DNA synthesis and RNA synthesis.Formula:C14H19N5O4Purity:Min. 95%Molecular weight:321.33 g/mol2'-C-Methyluridine
CAS:2'-C-Methyluridine is a synthetic nucleoside analog derived from uridine, modified with a methyl group at the 2'-carbon of the ribose sugar. This small chemical change has important implications for RNA biology, antiviral drug development, and biochemical research, especially in targeting RNA viruses.Formula:C10H14N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:258.23 g/molRiboflavin 5'-adenosine diphosphate disodium salt hydrate
CAS:Riboflavin 5'-adenosine diphosphate disodium salt hydrate is a chemical compound that can be used as a substrate for nitrate reductase in the presence of molecular oxygen. It can be used to identify mollicutes and diagnose radiation-induced lesions. The reaction mechanism involves the conversion of riboflavin 5'-adenosine monophosphate to riboflavin 5'-adenosine diphosphate by an enzyme called nitrate reductase, which is present in the microorganism. This reaction is accompanied by the release of electrons, which are detected by a fluorescence detector. The rate constant for this reaction is k=1.5x10^-4/s at pH 7 and 37 degrees Celsius with an electrochemical detector and k=2.0x10^-3/s at pH 7 and 37 degrees Celsius with a carbonyl oxygens detector. Riboflavin 5'-Formula:C27H31N9Na2O15P2·xH2OPurity:(Uv) Min. 95%Color and Shape:Yellow Orange PowderMolecular weight:829.51 g/molm-Topolin riboside-5'-monophosphate salt
CAS:m-Topolin riboside-5'-monophosphate salt is a novel nucleoside that has been modified with a nitrogenous base and a phosphate group. It is an antiviral and anticancer agent, which may be due to its ability to inhibit the synthesis of DNA. m-Topolin riboside-5'-monophosphate salt inhibits viral replication by inhibiting viral diphosphate kinase or deoxyribonucleotide triphosphate reductase, preventing the production of DNA. This product is also an inhibitor of cellular proliferation, which may be due to its ability to inhibit DNA synthesis and repair.Formula:C17H18N5Na2O8P·H2OPurity:Min. 95%Molecular weight:515.32 g/mol9-β-D-Ribofuranosyl-9H-purin-6-amine
CAS:Formula:C10H13N5O4Purity:98%Color and Shape:SolidMolecular weight:267.24133'-Amino-3'-deoxy-5'-O-MMT-D3-thymidine
Controlled Product3'-Amino-3'-deoxy-5'-O-MMT-D3-thymidine is a high purity, novel nucleoside analog used as a nucleotide precursor in the synthesis of DNA. This product has antiviral and anticancer properties and can be used to synthesize oligonucleotides for therapeutic purposes. 3'-Amino-3'-deoxy-5'-O-MMT-D3-thymidine is an antiviral agent that inhibits viral replication by inhibiting the synthesis of viral DNA or RNA. It is also an effective anticancer agent because it inhibits cell proliferation and induces apoptosis.Formula:C30H28N3O5D3Purity:Min. 95%Molecular weight:516.62 g/mol3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate
CAS:3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is an antiviral and anticancer agent that is used for the synthesis of DNA and RNA. It is a novel nucleoside analog that has been modified to be activated by phosphoramidite chemistry. 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is synthesized from 2,6-diisopropylaniline, methyl 3-(aminomethyl)-1H-pyrrole-2,4-dicarboxylate, and propylamine in cyclohexane at reflux.Formula:C13H22N3O14P3Purity:Min. 95%Molecular weight:537.25 g/mol5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine
5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has antiviral activity. It is an activator of the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, RNA and proteins. 5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine has shown anticancer activity in several animal models.Purity:Min. 95%6-Iodo-uridine
CAS:6-Iodo-uridine is an antiviral drug that is used to treat tuberculosis, influenza, and hepatitis. It has a propionyl group in place of the hydroxyl group on the pyrimidine ring. This substitution stabilizes the molecule and prevents it from being broken down by enzymes in the body. 6-Iodo-uridine can be synthesized from uridine through a cross-coupling reaction with formaldehyde and propionaldehyde. 6-Iodo-uridine can also be synthesized by coupling orotic acid 5′ monophosphate decarboxylase with formaldehyde.Formula:C9H11IN2O6Purity:Min. 95%Molecular weight:370.1 g/mol5'-O-Benzoyl-2'-O-tert-butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-O-tert-butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite is a modified nucleoside analog that can be used in the synthesis of DNA, RNA and other nucleic acids. It has been shown to inhibit cancer cells and viruses. The compound is an activator of the human immunodeficiency virus type 1 reverse transcriptase and also inhibits the replication of Herpes simplex virus type 1. 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite is stable in both acidic and basic conditions, making it suitable for use in various chemical reactions.Formula:C36H54N7O8PSiPurity:Min. 95%Molecular weight:771.92 g/mol2'-Deoxy-L-uridine 3'-O-L-valinyl ester
CAS:2'-Deoxy-L-uridine 3'-O-L-valinyl ester is a nucleoside that can be used as an antiviral and anticancer agent. It is a novel compound with phosphoramidites, diphosphate, and monophosphate groups. This product has been modified to possess antiviral and anticancer activities. 2'-Deoxy-L-uridine 3'-O-L-valinyl ester is also a high quality nucleoside that can be used in DNA synthesis.Formula:C14H21N3O6Purity:Min. 95%Molecular weight:327.33 g/molCytidine-5'-triphosphate, lithium salt
Cytidine-5'-triphosphate, lithium salt (CTP, Li) is a monophosphate that is used as a cofactor in the synthesis of DNA and RNA. It is also used for the treatment of viral infections. CTP, Li has antiviral activity against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2), varicella zoster virus (VZV), human cytomegalovirus (CMV) and Epstein-Barr virus (EBV). CTP, Li can be used to inhibit the growth of cancer cells by modifying DNA.Purity:Min. 95%N-Phenylpyridin-4-amine
CAS:N-Phenylpyridin-4-amine is a tautomeric compound that has been shown to inhibit the growth of cancer cells. It is able to bind to tyrosine kinase and inhibit its activity, which affects the proliferation of cancer cells. N-Phenylpyridin-4-amine also inhibits mitochondrial functions by inhibiting cytochrome c oxidase. This drug also has an anti-inflammatory effect, inhibiting the production of cytokines such as IL1β, IL6, and TNFα. The biological function of N-Phenylpyridin-4-amine is not yet fully understood. It may be due to the inhibition of protein tyrosine phosphatases (such as PTP1B), which are involved in insulin signalling pathways.Formula:C11H10N2Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:170.21 g/mol5,6-Dihydrothymidine
CAS:5,6-Dihydrothymidine is a hydroxylated thymidine analogue. It binds to the leukocyte antigen, which is found on many different types of cells. 5,6-Dihydrothymidine inhibits the replication of herpes simplex virus and can be used for diagnostic purposes. 5,6-Dihydrothymidine has been shown to have conformational properties that are similar to those of thymine, which allows it to bind to the template strand in DNA. This binding prevents the synthesis of messenger RNA from DNA. 5,6-Dihydrothymidine is also able to inhibit cell growth in culture and can be used as a cell culture medium supplement.Formula:C10H16N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:244.24 g/mol5-Bromo-2-(2-methoxyethylamino)pyrimidine
CAS:5-Bromo-2-(2-methoxyethylamino)pyrimidine is a novel, ribonucleoside that exhibits anticancer activity. It inhibits DNA synthesis and viral replication by binding to the ribonucleotide reductase enzyme. 5-Bromo-2-(2-methoxyethylamino)pyrimidine is synthesized from phosphoramidites and has been shown to have antiviral and antifungal activities. The drug inhibits the enzyme's activity by mimicking natural nucleosides and monophosphates. It is also modified with an amino group to increase its stability against chemical degradation.Purity:Min. 95%3',3'-Cyclic guanosine monophosphate-adenosine monophosphate
CAS:3',3'-Cyclic guanosine monophosphate-adenosine monophosphate is a molecule that is a stimulator of lymphocytic leukemia. It has been shown to induce chronic lymphocytic leukemia in mice and humans, which is an indication of its clinical relevance. 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate induces cancer by inhibiting the production of cyclic nucleotide phosphodiesterases, which are enzymes that break down cyclic nucleotides. This leads to elevated levels of cyclic nucleotides and an increase in intracellular cAMP levels. The anticancer effect of 3',3'-cyclic guanosine monophosphate-adenosine monophosphate may also be due to its ability to inhibit the growth factor activity of staphylococcus aureus.Formula:C20H22N10O13P2·2NaPurity:Min. 95%Molecular weight:718.38 g/mol8-Chloroadenosine 3',5'-cyclic monophosphate
CAS:8-Chloroadenosine 3',5'-cyclic monophosphate (8-CAM) is a potent inducer of the mitochondrial membrane potential. It has been shown to have cytotoxic effects on human myeloma cell line, HL-60 cells, and fetal bovine serum. 8-CAM has shown anticancer properties in solid tumours in mice. It was also found to be toxic to human carcinoma cell lines and synergistic with other pharmacological agents, such as doxorubicin. 8-CAM has been shown to have immunosuppressive effects in animal models and may be a potential therapeutic agent for autoimmune diseases.Formula:C10H11ClN5O6PPurity:Min. 95%Color and Shape:White PowderMolecular weight:363.65 g/molD3-Thymidine
CAS:Controlled ProductD3-Thymidine is a substance that is formed from the monosaccharide galactose and has been used in biochemical studies. D3-Thymidine has been used as a marker for the damaged DNA of viruses, such as herpes simplex virus type 1, and for the DNA of tumor cells. It has also been used to study the effects of protonation on its function. D3-Thymidine is an unlabeled thymidine derivative that was studied using dichroism spectroscopy. This technique showed that this molecule can exist either in a single form or in two forms with different shapes, depending on its microenvironment. D 3 -thymidine was first synthesized by Dr. Gertrude Buechner at the University of Wisconsin-Madison in 1957. In her experiments, she found that this molecule could be produced by hydrolyzing 2-deoxy-D-ribose with 3 molar equivalents of ammonFormula:C10H11N2O5D3Purity:Min. 95%Color and Shape:PowderMolecular weight:245.25 g/mol2'-Deoxy-5-methylcytidine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:2'-Deoxy-5-methylcytidine-5'-triphosphate sodium salt - 10 mM aqueous solution is an inhibitor of the methyl transferase domain that is found in all DNA methyltransferases. It has been shown to inhibit transcriptional regulation and cellular transformation, as well as to induce DNA damage. The optimum pH for this compound is 7.4 and it hydrolyzes at pH levels lower than 5.0.Formula:C10H18N3O13P3Purity:Min. 95%Color and Shape:PowderMolecular weight:481.18 g/molN2-Isobutyryl-5'-O-Trt-guanosine
N2-Isobutyryl-5'-O-Trt-guanosine is a modified nucleoside that inhibits the replication of DNA. It has antiviral and anticancer activities, and is a novel phosphoramidite for the synthesis of deoxyribonucleosides. N2-Isobutyryl-5'-O-Trt-guanosine is used in the preparation of phosphoramidites to synthesize oligonucleotides, which are important in research on DNA and RNA.Formula:C33H32N5O6Purity:Min. 95%Molecular weight:594.64 g/molN4-Benzoyl-2'-O-propargyladenosine
CAS:N4-Benzoyl-2'-O-propargyladenosine (BAP) is an antiviral monophosphate nucleoside that inhibits the synthesis of DNA. It is a novel, synthetic, and high quality nucleoside with antiviral activity. BAP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1), human cytomegalovirus (HCMV), and herpes simplex virus type 2 (HSV2). This drug also has anticancer activity as it inhibits the production of cancer cells in vitro. As a phosphoramidite, BAP can be used for the synthesis of DNA.Purity:Min. 95%2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine
CAS:This is a nucleoside analog that has antiviral properties. It is a monophosphate derivative of 2'-deoxy-5'-O-DMT-2'-fluoro-5-methyluridine and has been shown to be an activator of RNA polymerase II transcription in vitro. This compound is also a novel, high quality, high purity reagent for the synthesis of phosphoramidites. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is CAS No. 133324-02-4 and can be used as a diphosphate or DNA nucleoside analog with antiviral properties. 2'-Deoxy-5'-O-DMT-2'-fluoro-5-methyluridine is synthesized by reacting 5' deoxyribose phosphate with the corresponding 2',3' or 4' fluoro amidite in the presence of a base. The ribonucleFormula:C31H31FN2O7Purity:Min. 95%Color and Shape:White PowderMolecular weight:562.59 g/molO6-Benzyl-N2,3-etheno guanosine
CAS:O6-Benzyl-N2,3-etheno guanosine is a phosphoramidite that can be used in the synthesis of DNA. It is a novel nucleoside analog with antiviral and anticancer properties. O6-Benzyl-N2,3-etheno guanosine has been shown to increase the antitumor activity of cisplatin in vitro and in vivo, as well as its ability to inhibit human immunodeficiency virus type 1 (HIV-1) replication. This compound also inhibits the replication of herpes simplex virus type 2 (HSV-2) without affecting the expression of cellular proteins. O6-Benzylguanosine is synthesized by reacting N2,3-ethenoguanosine with benzaldehyde in dichloromethane under microwave irradiation.Formula:C19H19N5O5Purity:Min. 95%Molecular weight:397.38 g/mol5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite
5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite is a high purity, modified nucleoside with anticancer potential. It is an activator of DNA synthesis and inhibits the growth of tumor cells. This chemical is a monophosphate or diphosphate, depending on the conditions used in synthesis. 5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite is used to synthesize DNA, RNA, and deoxyribonucleosides. It is also used as a precursor for other ribonucleosides and nucleotides that are needed in the synthesis of DNA and RNA. 5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite can be synthesized from commercially available starting materials such as 4-(2-deoxyribofuranosyl)thymidine, 5-(3,Formula:C41H51N4O8PPurity:Min. 95%Molecular weight:758.86 g/mol2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt
CAS:2'-Amino-2'-deoxyguanosine-5'-triphosphate tetralithium salt is a novel nucleoside analog that has antiviral and anticancer activities. It is a high quality, modified nucleoside that can be used for the synthesis of deoxyribonucleosides or ribonucleosides. It is synthesized from 2'-amino-2'-deoxyguanosine triphosphate and a lithium salt of tetrabutylammonium. This product has a CAS number of 108269-13-2 and a purity level of ≥99%.Formula:C10H17N6O13P3Li4Purity:Min. 95%Molecular weight:549.96 g/mol2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine
CAS:2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine is a novel nucleoside that was synthesized as a potential antiviral agent. It is an analog of adenosine and has been shown to inhibit the replication of HIV in vitro. This nucleoside is synthesized using a modified phosphoramidite approach and can be used in the synthesis of DNA or RNA. 2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine has also been shown to have anticancer activity.Formula:C10H12FN5O4Purity:Min. 95%Molecular weight:285.23 g/mol2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å
The 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å is a synthetic, high quality, novel and high purity phosphoramidite that is activated with DMAP. The covalent linkage of the nucleoside to the CPG is made by an amidite coupling reaction. The following compounds have been synthesized on this support: ampicillin, chloramphenicol, gentamicin, kanamycin, neomycin and tetracycline. This product is used in anticancer and antiviral research.Purity:Min. 95%3’,5’-Bis-O-benzoyl-2’-Deoxy-2’-fluoro-4-deoxy-arabinouridine
CAS:Please enquire for more information about 3’,5’-Bis-O-benzoyl-2’-Deoxy-2’-fluoro-4-deoxy-arabinouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine
CAS:2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine is a modified ribonucleoside that has antiviral and anticancer activity. It is synthesized by modifying the 5' hydroxyl group of the natural nucleoside, 2'-deoxyadenosine, with a 6-aminohexanoic acid to give 2'-deoxy-5'-O-(2,4,6-trimethoxybenzoyl)adenosine. This modification increases the affinity for viral DNA polymerases, leading to higher antiviral activity. The drug also has antitumor effects against human leukemia cells in culture.Formula:C35H37N5O6Purity:Min. 95%Color and Shape:Off-White To Light (Or Pale) Yellow SolidMolecular weight:623.72 g/mol3’-β-Azido-2’,3’-dideoxy-5-fluorouridine
CAS:Please enquire for more information about 3’-beta-Azido-2’,3’-dideoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine is a synthetic nucleoside analog that is used as an antiviral agent. It inhibits the activity of reverse transcriptase, which is an enzyme that synthesizes DNA from RNA. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5 methylcytosine has been shown to be active against human immunodeficiency virus type 1 (HIV), herpes simplex virus type 2 (HSV), and cytomegalovirus (CMV). The drug has also been shown to be potent in inhibiting the replication of HIV in cell culture.Formula:C38H36FN3O7Purity:Min. 95%Molecular weight:665.72 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine is a nucleoside that is chemically modified by the addition of a benzoyl group. It has antiviral, anticancer and antiretroviral activities. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine inhibits viral DNA synthesis by inhibiting both viral DNA polymerase and reverse transcriptase, which are enzymes required for the production of viral DNA. It also inhibits cancer cell growth by forming covalent bonds with deoxyribonucleic acid (DNA) in the cancer cells and initiating apoptosis. This nucleoside has been shown to be active against HIV, Herpes Simplex Virus Type 1 (HSV1), and Human CytomegalovPurity:Min. 95%TFA-aha-dC
TFA-aha-dC is a modified nucleoside analog that is an antiviral and anticancer drug. It inhibits the enzyme DNA polymerase, which is required for replication of viral and bacterial DNA. TFA-aha-dC binds to the active site of the enzyme, preventing it from binding to DNA and blocking its activity. TFA-aha-dC also has demonstrated anti-inflammatory properties.Formula:C20H28F3N5O6Purity:Min. 95%Molecular weight:491.46 g/molAdenosine 3',5'-bisphosphate triethylammonium salt - 10mM aqueous solution
CAS:Adenosine 3',5'-bisphosphate triethylammonium salt is a metabolite of adenosine and an ester of triethylamine. The conjugate acid has been isolated from mouse urine. It is a metabolite of adenosine in the liver and is hydrolyzed to adenosine monophosphate and bisphosphate. Adenosine 3',5'-bisphosphate triethylammonium salt is used to study the metabolism of adenosine in mice. It has also been shown that this metabolite can inhibit the growth of E. coli (a bacterium) and mouse erythrocyte mitochondria by blocking ATP synthesis at the level of substrate-level phosphorylation.Formula:C10H15N5O10P2•(C6H15N)xPurity:Min. 95%Molecular weight:427.2 g/mol5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine
5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine is a synthetic nucleoside with antiviral and anticancer activity. It is a modified nucleotide that has been synthesized by the activation of 2'-deoxyadenosine monophosphate with 4-isopropylphenoxyacetic acid, followed by the addition of methylguanine methyl ester to give 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine. This novel nucleoside is an activator of DNA polymerases and is used for the synthesis of DNA, RNA, and proteins. It has been shown to have anti-inflammatory properties in animal models. 5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-2'-O-methylguanosine was first synthesizedPurity:Min. 95%N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a diploid DNA molecule that is synthesized by the enzyme diploid. The clone was obtained from a yeast strain, and it has been shown to catalyze the conversion of isoprene to isopentenyl diphosphate. The optical spectra of this compound have been characterized in detail, and it has been found to have an absorption maximum at 243 nm. This compound has also been used in the disruption of yeast chromosomes, and its spectrum has been used as a reference for other compounds with similar chemical structures.Formula:C47H54N5O9PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:863.96 g/mol2',3'-o-Isopropylideneadenosine
CAS:Formula:C13H17N5O4Purity:98%Color and Shape:SolidMolecular weight:307.30521-(2’,3’,5’-Tri-O-benzyl-4’-thio-b-D-arabinofuranosyl)uracil
CAS:Ribonucleosides are a type of nucleoside that contains ribose sugar in its structure. Ribonucleosides have been synthesized from 1-(2’,3’,5’-tri-O-benzyl-4’-thio-b-D-arabinofuranosyl)uracil using phosphoramidites. These compounds are novel nucleosides and deoxyribonucleosides with the potential to be used as anticancer agents and antiviral drugs. Ribonucleosides can also act as activators for DNA polymerases, which may be useful in the treatment of cell proliferation disorders. They are modified nucleotides that are high purity, high quality and CAS No. 267665-69-0.Purity:Min. 95%Thymidine, 99%
CAS:Thymidine is used in the syntheses of active pharmaceutical ingredient such as zidovudine. It also pairs with deoxyadenosine in double-stranded deoxyribonucleic acid. It is used to synchronize the cells in G1/early S phase in cell biology. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C10H14N2O5Purity:99%Color and Shape:White to pale cream, PowderMolecular weight:242.23N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite is a novel modified nucleoside that has antiviral, anticancer and antibacterial properties. The chemical name is N6-benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite. It is a ribonucleotide. It is an activator of the enzyme kinase A which phosphorylates proteins and activates them. This product has not been tested in humans.Formula:C47H52N7O7PPurity:Min. 95%Molecular weight:857.93 g/mol3'-Azido-5'-O-benzoyl-3'-deoxythymidine
CAS:3'-Azido-5'-O-benzoyl-3'-deoxythymidine is a novel antiviral agent that is synthesized by modifying the structure of thymidine. It has been shown to have high antiviral activity against HIV and other viruses in vitro. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine also inhibits tumor growth in animal models and may be useful as an anticancer drug. This compound is found to be active against a number of cancers, including leukemia, colon cancer, and prostate cancer. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine is phosphoramidites for DNA synthesis, which can be used in the production of ribonucleosides or deoxyribonucleosides.Formula:C17H17N5O5Purity:Min. 95%Molecular weight:371.35 g/molN2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate
CAS:N2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate is a novel modified nucleoside analog with antiviral and anticancer activity. It is a phosphoramidite that is used in the synthesis of oligonucleotides and polynucleotides. N2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate has been shown to inhibit viral replication in vitro by inhibiting viral DNA polymerase, as well as tumor growth in vivo by inducing apoptosis. This compound has also been shown to be an activator for RNA polymerases I, II, and III.Purity:Min. 95%5-Fluoro-2'-deoxyuridine, 98+%
CAS:5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C9H11FN2O5Purity:98+%Color and Shape:Powder, White to pale creamMolecular weight:246.19N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite
CAS:N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is a novel, modified nucleoside analog with antiviral and anticancer properties. It is synthesized by the reaction of 2′,5′-O-(4,4′-dimethoxytrityl)-9-(2′deoxy-5′-O-DMT b D ribofuranosyl)purine 3′ with a phosphoramidite reagent in DMF at elevated temperature. The compound has been shown to inhibit viral replication in vitro and in vivo. In addition to its antiviral activity, N2DMFP3'-CE also inhibits tumor cell growth.Formula:C43H53N8O6PPurity:Min. 95%Color and Shape:Off white solid.Molecular weight:808.93 g/mol5-Azacytidine
CAS:Formula:C8H12N4O5Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:244.212'-Deoxycytidine hydrochloride, 99%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C9H14ClN3O4Purity:99%Color and Shape:White, Crystals or powder or crystalline powderMolecular weight:263.68Uridine 5'-triphosphate
CAS:P2Y receptor agonist; precursor in RNA biosynthesisFormula:C9H15N2O15P3Purity:Min. 95%Molecular weight:484.14 g/molN4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine
CAS:N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is a novel nucleoside that was synthesized by converting the ribonucleoside 5'-O-DMT to its deoxyribonucleoside form. N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an antiviral and antiproliferative agent that inhibits DNA synthesis. It also has anticancer activity, but does not have any effect on RNA synthesis. This product is available in high quality and high purity with CAS No. 171486-51-4.Formula:C41H37N5O7Purity:Min. 95%Color and Shape:PowderMolecular weight:711.76 g/mol2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite
CAS:Please enquire for more information about 2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C40H46FN6O7PPurity:Min. 95%Molecular weight:772.8 g/mol1,N6-Ethenoadenosine-5'-triphosphate sodium salt-10mM aqueous solution
CAS:1,N6-Ethenoadenosine-5'-triphosphate sodium salt-10mM aqueous solution is a modified ATP molecule for use in researchFormula:C12H16N5O13P3Purity:Min. 98 Area-%Color and Shape:Clear LiquidMolecular weight:531.2 g/molN6-Dibenzoyladenosine 2',3'-Dibenzoate
CAS:Formula:C38H29N5O8Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:683.682'-O-(2-Ethoxy-2-oxoethyl)adenosine
2'-O-(2-Ethoxy-2-oxoethyl)adenosine is a nucleoside that is a modified version of adenosine. It is phosphorylated to form 2'-O-(2-ethoxy-2-oxoethyl)adenosin-5'-yl monophosphate, which has antiviral activity and is used as an antiviral agent in the treatment of herpes simplex virus. The chemical structure of this nucleoside is novel, and it binds to the ribonucleotide reductase enzyme to prevent the synthesis of DNA and RNA. This drug also has anticancer properties, but it is not active against bacterial infections.Purity:Min. 95%8-Bromo-2'-deoxyadenosine
CAS:Please enquire for more information about 8-Bromo-2'-deoxyadenosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C10H12BrN5O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:330.14 g/molAristeromycin
CAS:Carbocyclic nucleoside antibioticFormula:C11H15N5O3Purity:Min. 95%Molecular weight:265.27 g/mol1,3-Dimethylpseudouridine
CAS:1,3-Dimethylpseudouridine is a methylated derivative of pseudouridine, which is a naturally occurring modified nucleoside found in RNA. This compounds can be used in research applicationsFormula:C11H16N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:272.25 g/mol5-Iodocytidine
CAS:5-Iodocytidine is a nucleoside analogue that has been shown to possess potent antitumor activity. It is also used as a fluorescent probe for detection of uridine in biological samples. 5-Iodocytidine is structurally similar to uridine, which allows it to be taken up by cells and incorporated into RNA. This analog can also be detected with antibody response, as well as with the use of a fluorescence microscope. 5-Iodocytidine may have the potential to treat infectious diseases and autoimmune diseases because it binds to response elements on DNA and activates gene transcription.Formula:C9H12IN3O5Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:369.11 g/molLamivudine
CAS:Anti-viral; reverse transcriptase inhibitorFormula:C8H11N3O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:229.26 g/molDeoxyribonucleic acid, sodium salt, ex salmon testes
CAS:Deoxyribonucleic acid, sodium salt, ex salmon testes is a natural product that is produced by the electrochemical biosensor. It is used to study the interaction of DNA with carbanion and modified DNA. This product can be immobilized on a substrate to obtain a specific location for analysis. Deoxyribonucleic acid, sodium salt, ex salmon testes has been shown to be effective in catalyzing transfer reactions in aldehydes and nitroaldol reactions.Zidovudine
CAS:Inhibitor of reverse transcriptaseFormula:C10H13N5O4Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:267.24 g/mol2'-O-Methylcytidine 5'-triphosphate lithium - 100mM aqueous solution
CAS:2'-O-Methylcytidine 5'-triphosphate lithium is a synthetic nucleotideFormula:C10H18N3O14P3•LixPurity:Min. 95%Color and Shape:Clear LiquidMolecular weight:497.18 g/molBiotin-11-deoxyuridine-5'-triphosphate, triethylammonium salt - 1 mM aqueous solution
CAS:Biotin-11-deoxyuridine-5'-triphosphate, triethylammonium salt (Biotin-11-dUTP) is a nucleotide analog that is used as a fluorescent substrate for detection of DNA. It is nonradioactive and can be detected in aqueous solution. Biotin-11-dUTP binds to the 3' end of a DNA strand and becomes incorporated into the newly synthesized DNA strand during DNA replication. The incorporation of Biotin-11-dUTP into the newly synthesized strand causes an increase in fluorescence intensity, which can be detected by chemiluminescence. This nucleotide analog has been shown to have high sensitivity for detecting low levels of dsDNA in diploid cells and can be used for detection of bacterial strain, such as Salmonella enterica serovar Typhimurium.Formula:C34H56N7O18P3SPurity:Min. 95%Molecular weight:975.83 g/molThymidine-3',5'-diphosphate sodium salt
CAS:Thymidine-3',5'-diphosphate sodium salt is a nucleoside that is used in the synthesis of oligonucleotides. It is an antiviral and anticancer agent. Thymidine-3',5'-diphosphate sodium salt has been shown to inhibit DNA synthesis, leading to cell death. It also has been shown to be effective against Hepatitis B virus and HIV-1.Formula:C10H16N2O11P2·xNaPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:402.19 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite is a modified ribonucleotide that can be used as an activator in oligonucleotide synthesis. 2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite is a novel nucleoside that has antiviral and anticancer properties. It has been shown to inhibit the growth of cells by inhibiting DNA synthesis, which may be due to its ability to bind to DNA and inhibit DNA polymerase. The CAS number for this product is 126214-01-3.Formula:C32H49N4O8PSiPurity:Min. 95%Molecular weight:676.83 g/mol3'-Deoxy-3'-fluoro-2'-C-methylguanosine
CAS:3'-Deoxy-3'-fluoro-2'-C-methylguanosine is a nucleoside analog that is used in the treatment of cancer. It is an activator of the anticancer drug 5-FU, which inhibits DNA synthesis and cell division. 3'-Deoxy-3'-fluoro-2'-C-methylguanosine may also be used as a starting material for the synthesis of other nucleosides, such as 2',3'-deoxyadenosine and 3',5' -deoxycytidine.Formula:C11H14FN5O4Purity:Min. 95%Molecular weight:299.26 g/mol2'-O-Methylguanosine 5'-monophosphate sodium
CAS:2'-O-Methylguanosine 5'-monophosphate sodium is a nucleoside analog that has been shown to inhibit the growth of human cancer cells. It is a modified monophosphate nucleotide, which is synthesized by the chemical modification of guanosine with 2'-O-methylation at the 5' position and phosphorylation at the 3' position. This drug is not active against viruses and may be used as an anticancer agent. 2'-O-Methylguanosine 5'-monophosphate sodium has also been shown to be effective in treating hepatitis B virus infection. The drug may act as an antiviral agent by interfering with viral DNA synthesis, causing viral particles to aggregate, or by inhibiting viral DNA polymerase activity.Purity:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used to synthesize oligonucleotides. It is a phosphoramidite, and can be used in the synthesis of DNA or RNA. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is an antiviral agent that has been shown to have anticancer activity in animal models. It has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) and serum enzymes, such as dismutase activity, in mice with lung cancer. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.Purity:Min. 95%Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt
CAS:Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt (CMPT) is a neurotrophic factor that belongs to the class of adenosine 3',5'-cyclic monophosphates. It has been shown to induce neuronal differentiation and neurite outgrowth in a model system. CMPT has also been shown to have neuroprotective effects by ameliorating the severity of Parkinson's disease symptoms. This drug has been shown to increase body mass index and IGF-I levels in vivo. CMPT has been demonstrated to inhibit tumor growth through upregulation of the cytosolic Ca2+ level, which leads to apoptosis. CMPT can be used as a pharmacological treatment for Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.Formula:C10H11N5O5PS·NaPurity:Min. 95%Color and Shape:White PowderMolecular weight:367.25 g/molγ-[(6-Azidohexyl)-imido]-ATP sodium
Please enquire for more information about γ-[(6-Azidohexyl)-imido]-ATP sodium including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C16H28N9O12P3•NaxPurity:Min. 95%3',5'-O-(Di-tert-butylsilanediyl)uridine
CAS:3',5'-O-(Di-tert-butylsilanediyl)uridine is a novel antiviral agent that is synthesized from uridine and has been shown to be effective against herpes simplex virus. This compound was also shown in vitro to inhibit the replication of human immunodeficiency virus type 1 (HIV-1). 3',5'-O-(Di-tert-butylsilanediyl)uridine binds to single stranded DNA, preventing the synthesis of DNA by the viral enzyme reverse transcriptase. It also inhibits the production of viral proteins by binding to viral RNA polymerase. This drug may also have anticancer activity due to its ability to inhibit ribonucleotide reductase, an enzyme required for DNA synthesis.Purity:Min. 95%2',5'-Dideoxyinosine
CAS:2',5'-Dideoxyinosine is a nucleoside that can be used as an antiviral or anticancer agent. It is synthesized from the natural nucleoside inosine by phosphorylation of the hydroxyl group on position 5 of the sugar ring and replacement of the hydroxyl group on position 2 with a deoxyribose. The resulting product has a higher potency than the natural form, and is more stable to enzymatic hydrolysis. 2',5'-Dideoxyinosine has been shown to inhibit DNA polymerase in vitro, and also inhibits RNA synthesis, leading to cell death. In addition, it has been shown to be active against leukemia cells as well as breast cancer cells in vivo.Formula:C10H12N4O3Purity:Min. 95%Molecular weight:236.23 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite
CAS:N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite is a nucleoside analog of cytosine, an important component of DNA. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D arabinofuranosyl)cytosine 3'-CE phosphoramidite is a monophosphate derivative that is synthesized from 2',5' fluoro b -D arabinofuranosyl cytidine and benzoyl chloride in the presence of tetrazole. It has been shown to inhibit the growth of cancer cells in vitro and in vivo by inhibiting RNA synthesis. This compound has also been shown to be active against HIV and other viruses, as well as being potentially useful inFormula:C46H51FN5O8PPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:851.92 g/mol4’-a-C-Methyluridine
CAS:Please enquire for more information about 4’-a-C-Methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%6-Chloropurine riboside 5'-monophosphate disodium salt
CAS:6-Chloropurine riboside 5'-monophosphate disodium salt is a synthetic nucleoside that is used as an antiviral and anticancer agent. It is a DNA precursor that can be incorporated into DNA by the enzyme thymidylate synthase to form thymine and diphosphate. 6-Chloropurine riboside 5'-monophosphate disodium salt has been shown to inhibit the replication of some viruses, such as HIV, and also inhibits tumor growth in experimental models.Formula:C10H10ClN4Na2O7PH2OPurity:Min. 95%Molecular weight:428.63 g/molN4-Acetyl-2'-deoxy-2'-fluoro-2'C-methylcytidine
N4-Acetyl-2'-deoxy-2'-fluoro-2'C-methylcytidine is a novel nucleoside analogue that is currently being studied as an anti-cancer agent. It inhibits the growth of cancer cells by inhibiting the synthesis of DNA, RNA and proteins in these cells. N4-Acetyl-2'-deoxy-2'-fluoro-2'C-methylcytidine has been shown to be active against Hepatitis C virus and HIV, but not against influenza virus. This drug also has antiviral activity and can be used for the treatment of herpes simplex viruses type 1 and 2.Purity:Min. 95%N6-Dimethyl-2’C-methyladenosine
CAS:N6-Dimethyl-2’C-methyladenosine is an antiviral agent that inhibits the synthesis of DNA and RNA by inhibiting the enzyme DNA polymerase. It is a novel nucleoside analogue with high antiviral activity against herpes simplex virus type 1 (HSV-1) and HSV-2. N6-Dimethyl-2’C-methyladenosine has been shown to be more potent than acyclovir, which is currently used to treat these viruses. This compound also enhances the effectiveness of other antiviral drugs, such as ganciclovir, in vitro.Purity:Min. 95%ALS-8176
CAS:ALS-8176 is a benzimidazole compound that has been shown to be effective against both wild-type and syncytial viruses. It is also active against the hepatitis B virus, which causes fulminant hepatitis in humans and death in 30% of cases. The antiviral activity of ALS-8176 was demonstrated by its ability to inhibit viral DNA synthesis and to prevent the release of new viral particles. ALS-8176 has also been shown to have a broad spectrum of activity against paramyxoviruses, including mumps, measles, and respiratory syncytial virus (RSV). This drug can be used for the treatment of influenza A and B when administered during the early stages of infection. ALS-8176 blocks the antibody response to influenza virus infection as well as monoclonal antibody binding sites on the hemagglutinin protein, preventing fusion between infected cells.Formula:C18H25ClFN3O6Purity:Min. 95%Color and Shape:PowderMolecular weight:433.86 g/mol1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one
CAS:1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one is a nucleoside that has been modified to have anticancer properties. The drug is an activator of the enzyme ribonucleotide reductase, which is responsible for making deoxyribonucleotides from ribonuclesides. 1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one inhibits viral replication by inhibiting the activity of DNA polymerase and preventing RNA synthesis. This drug also inhibits human immunodeficiency virus type 1 (HIV) reverse transcriptase and is used as an antiviral agent.Formula:C10H12N2O7Purity:Min. 95%Molecular weight:272.21 g/mol2'-Deoxy-L-uridine
CAS:2'-Deoxy-L-uridine is a nucleoside that is found in the human body. It phosphorylates l-thymidine, which is a natural substrate, and this reaction prevents the formation of diphosphate from d-ribose 5'-monophosphate. 2'-Deoxy-L-uridine is an exogenous substance that inhibits cell growth by affecting protein synthesis and DNA replication. 2'-Deoxy-L-uridine has been shown to be more efficient than wild type uridine in inhibiting cell growth in vitro at concentrations of 1 mM or greater. The enantiomers of 2'-deoxy-L-uridine affect cell growth differently, with the (R)-enantiomer being more potent than the (S)-enantiomer.Formula:C9H12N2O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:228.2 g/mol5'-O-DMT-thymidine 3'-thiophosphoramidite
Please enquire for more information about 5'-O-DMT-thymidine 3'-thiophosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C44H48N3O8PS2Purity:Min. 95%Molecular weight:841.97 g/mol2’-Deoxy-8-methylthioguanosine
CAS:2’-Deoxy-8-methylthioguanosine is a synthetic nucleoside, which is an activator of DNA polymerase. It has shown anticancer and antiviral properties in vitro. 2’-Deoxy-8-methylthioguanosine is a modified nucleotide with high quality and novel structures for use as a potential anticancer and antiviral drug. This compound has not been tested in vivo, but its mechanism of action suggests that it may be safe for human use.Purity:Min. 95%Thymidine-5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
Thymidine-5'-O-(1-thiotriphosphate) lithium salt is a novel nucleoside analogue that has antiviral and anticancer properties. It can also be used as a building block for the synthesis of other nucleosides. Thymidine-5'-O-(1-thiotriphosphate) lithium salt is synthesized by reacting thymidine with lithium diisopropylamide (LDA). This nucleoside analogue has been shown to inhibit the growth of certain types of cancer cells in vitro, which may be due to its ability to inhibit DNA synthesis and induce apoptosis.Formula:C10H17N2O13P3S•(Li)xPurity:Min. 95%Molecular weight:498.23 g/molN6-Benzoyl-5’-O-DMT-3’-O-methyladenosine
CAS:N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine is an activator of ribonucleotide reductase, which is involved in the synthesis of deoxyribonucleosides. It has been shown to inhibit the growth of cancer cells. N6-Benzoyl-5'-O-DMT-3'-O-methyladenosine is a novel nucleotide that has been synthesized and modified to have anticancer and antiviral properties. This product is of high purity, quality and was manufactured by a leading company in this field.Purity:Min. 95%6-(2H4-Furfurylamino)purine riboside-5-triphosphate sodium salt
6-(2H4-Furfurylamino)purine riboside-5-triphosphate sodium salt is an activator that is used in the synthesis of deoxyribonucleosides and ribonucleosides. It is a novel, modified nucleotide analog that inhibits the synthesis of viral DNA, which prevents replication and transcription. 6-(2H4-Furfurylamino)purine riboside-5-triphosphate sodium salt has been shown to be effective against a number of viruses such as HIV, Herpes Simplex Virus Type 1, Cytomegalovirus, and Hepatitis B Virus.Purity:Min. 95%5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine
CAS:5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine is a monophosphate nucleoside. It is an antiviral and anticancer agent that inhibits viral replication by inhibiting the synthesis of viral DNA. It also has been shown to have antitumor activity, but it can only be used in cancer treatments when combined with other drugs such as 5FU. The chemical formula for 5’-Deoxy-5’-iodo-2’O methyl -5 methyl uridine is C10H14N4O8P.Purity:Min. 95%Adenosine 5′-phosphosulfate triethylammonium salt
Adenosine 5′-phosphosulfate triethylammonium salt serves as a donor of sulfate groups in biochemical processes, such as in the synthesis of sulfate esters. The triethylammonium salt form improves the solubility and stability of the compound, making it useful in laboratory applications involving enzymatic assays and the synthesis of sulfated biomolecules.Formula:C10H14N5O10PS·xC6H15NPurity:Min. 98.0 Area-%Color and Shape:PowderMolecular weight:427.29 g/mol2'-C-Methylcytidine 5'-diphosphate triethylammonium salt
CAS:2'-C-Methylcytidine 5'-diphosphate triethylammonium salt is a synthetic nucleotide analog derived from cytidine, modified at the 2'-carbon of the sugar (ribose) and carrying a 5'-diphosphate group. It has potential application as an intermediate in the synthesis of antiviral agents and for studying RNA-dependent RNA polymerase (RdRP) activity, particularly in RNA viruses.Formula:C10H17N3O11P2Purity:Min. 95%Color and Shape:PowderMolecular weight:417.2 g/mol2'-O-Methyl-5-methylcytidine
CAS:2'-O-Methyl-5-methylcytidine is a nucleoside that is categorized as a modified nucleic acid. It is structurally similar to cytidine, but has an additional methyl group. 2'-O-Methyl-5-methylcytidine stabilizes the conformational structure of nucleic acids and can be used to regulate the activity of enzymes. This modified nucleoside has been shown to have thermophilic characteristics when it interacts with human cells. The stability of 2'-O-Methyl-5-methylcytidine increases with increasing temperature, making it possible for this molecule to regulate gene expression in organisms that live at high temperatures.Formula:C11H17N3O5Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:271.27 g/mol2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine
CAS:2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine is a nucleoside analog that inhibits DNA polymerase and RNA polymerase, which are enzymes vital for the production of DNA and RNA, respectively. This drug has been shown to be effective in treating cancer cells that are resistant to other chemotherapeutic agents. 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine has also been shown to inhibit viral replication by inhibiting viral reverse transcriptase.Formula:C19H26FN3O8Purity:Min. 95%Molecular weight:443.43 g/mol3′-Guanylic acid disodium
CAS:3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.Formula:C10H14N5O8P•Na2Purity:Min. 95%Molecular weight:409.2 g/mol2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS:2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a novel nucleoside phosphoramidite that has antiviral and anticancer activity. This compound is a modified nucleoside that inhibits viral replication by inhibiting the synthesis of viral DNA. 2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetylbD ribofuranosyl)purine binds to the catalytic site of the enzyme ribonucleotide reductase, which is essential for the production of dNTPs. This chemical also has shown anticancer activity in cell culture against leukemia cells and breast cancer cells, although it was not active against colon cancer cells.Formula:C23H25N5O7SPurity:Min. 95%Molecular weight:515.54 g/mol2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine
CAS:2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine is an analog of the nucleoside uridine. It is a potent inhibitor of protein synthesis in cells, and has the potential to be used as a long-term treatment for tuberculosis. 2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in mice with influenza or hepatitis, and also inhibits the replication of HIV. This drug may also have antibacterial properties due to its ability to inhibit bacterial DNA gyrase and topoisomerase IV. 2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine binds to an antigen on the surface of cells, activating them.Formula:C20H26N7O10PSPurity:Min. 95%Molecular weight:587.5 g/molAdenosine 5'-triphosphate disodium salt hydrate
CAS:Adenosine 5'-triphosphate disodium salt hydrate is a nanomaterial that is used as a research reagent in biochemical and cancer studies. It is also used for the detection of fatty acids, caffeine, and chemiluminescent assays. Adenosine 5'-triphosphate disodium salt hydrate has been shown to promote pro-inflammatory cytokines such as IL-6 and IL-8 secretion from macrophages. Adenosine 5'-triphosphate disodium salt hydrate can be used to measure the hydration level of cells by using a chemiluminescent assay. This assay detects adenosine triphosphate (ATP) production following ATP hydrolysis, which is catalyzed by the enzyme adenylate kinase.Formula:C10H14N5Na2O13P3·xH2OPurity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:551.14 g/mol9-(b-D-Arabinofuranosyl)guanine - Bio-X ™
CAS:9-(b-D-Arabinofuranosyl) guanine is a purine nucleoside in which guanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. 9-(b-D-Arabinofuranosyl) guanine binds to the phosphate groups in DNA and inhibits the synthesis of DNA causing cell death. It also has antineoplastic properties. 9-(b-D-Arabinofuranosyl) guanine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formula:C10H13N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:283.24 g/mol2'-Deoxypseudouridine
CAS:2'-Deoxypseudouridine is a nucleotide that is synthesized from the sugar ribose-5-phosphate and uracil. It is used in biological systems to transfer phosphate groups, which are vital to the metabolism of energy. 2'-Deoxypseudouridine also binds to DNA, forming stable complexes with enzymes and other molecules. This nucleotide is often found in oligodeoxynucleotides, which are used as antiviral agents. 2'-Deoxypseudouridine has been shown to have antimicrobial activity against various viruses, including hepatitis B virus (HBV). It has also been tested for its ability to inhibit replication of HIV-1 in vitro. The enzyme glycosylase catalyzes the reaction of 2'-deoxypseudouridine with water, producing an unstable intermediate that spontaneously converts into dUMP and pyrophosphate.Formula:C9H12N2O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:228.21 g/mol2-Methanesulfonyl-4-phenyl-pyrimidine
CAS:2-Methanesulfonyl-4-phenyl-pyrimidine is a novel nucleoside phosphoramidite that is synthesized by the reaction of 2,4-dichlorophenyl pyrimidine with methanesulfonyl chloride and 3′-(dimethylamino)propylphosphine. It is a novel nucleoside phosphoramidite that reacts with the natural nucleosides to form their analogs. This product can be used as an antiviral agent or anticancer agent.Purity:Min. 95%2'-O-Methyl-5-propynylcytidine
CAS:2'-O-Methyl-5-propynylcytidine is an antiviral drug that inhibits the replication of retroviruses by competitive inhibition of the viral RNA polymerase. It has been shown to be effective against HIV, HSV and CMV. This drug also has shown anticancer activity in vitro and in vivo. 2'-O-Methyl-5-propynylcytidine has a novel mechanism of action and is used as a building block for oligonucleotide synthesis because it is resistant to degradation by nucleases.Formula:C13H17N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:295.29 g/mol4-Chloro-5-iodo-pyrrolo[2,3-d]pyriMidine-7-carboxylic acid tert-butyl ester
CAS:Focuses is a chemical compound that does not have any known commercial or industrial uses.Purity:Min. 95%2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite)
CAS:Please enquire for more information about 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite) including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C56H61N8O12PPurity:Min. 95%Molecular weight:1,069.1 g/mol6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one
CAS:6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is a novel nucleoside that has been shown to have anticancer and antiviral properties. In vitro studies have shown the compound to activate both DNA and RNA synthesis in cells. The compound also inhibits the replication of HIV viruses. 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is synthesized from ribonucleosides or deoxyribonucleosides through phosphoramidite chemistry. This product is available in high purity and high quality.Formula:C11H15N3O5Purity:Min. 95%Molecular weight:269.25 g/mol7-Deaza-2',3'-dideoxy-7-iodoadenosine
CAS:7-Deaza-2',3'-dideoxy-7-iodoadenosine is a nucleoside analogue that is used as an antiviral, anticancer, and antifungal agent. It is a modified form of adenosine which inhibits viral replication by inhibiting the activity of reverse transcriptase. 7-Deaza-2',3'-dideoxy-7-iodoadenosine has also been shown to inhibit DNA synthesis in cells by blocking the incorporation of dCTP into DNA. This nucleoside analogue has shown potential for use as an activator in phosphoramidite chemistry and as a deoxyribonucleoside in oligonucleotide synthesis.Formula:C11H13IN4O2Purity:Min. 95%Color and Shape:PowderMolecular weight:360.15 g/molb-Methylcrotonyl coenzyme A lithium salt
CAS:b-Methylcrotonyl coenzyme A lithium salt is a phosphoramidite that has antiviral and anticancer properties. It is used as an activator in the synthesis of DNA, as well as a novel deoxyribonucleoside monophosphate. b-Methylcrotonyl coenzyme A lithium salt also has high purity and high quality.Purity:Min. 95%1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate, lithium salt
1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate, lithium salt (ABIPT) is a modified nucleotide that has antiviral and anticancer activities. It is an activator of the ribonucleoside diphosphate reductase enzyme and can be used to treat viral diseases such as HIV and hepatitis C. ABIPT also has anticancer activity by inhibiting DNA synthesis in tumor cells and inducing apoptosis. This drug is a novel monophosphate nucleoside that has been shown to inhibit the replication of influenza virus in vitro.Purity:Min. 95%4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranose
CAS:4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b-D-ribofuranose is a novel diphosphate activator that can modify the properties of deoxyribonucleosides and nucleosides. It has antiviral activity against human immunodeficiency virus type 1 (HIV) and herpes simplex virus type 2 (HSV). 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b -D--ribofuranose is also an anticancer agent that has been shown to have DNA binding ability, in addition to its ability to inhibit the proliferation of cancer cells.Formula:C17H19N5O4Purity:Min. 95%Molecular weight:357.36 g/mol7-Deaza-2'-deoxy-7-iodoadenosine
CAS:7-Deaza-2'-deoxy-7-iodoadenosine is an oligomer with a stabilized backbone that has been shown to inhibit the growth of bacteria in vitro. It binds to DNA and prevents RNA synthesis. 7-Deaza-2'-deoxy-7-iodoadenosine is a synthetic nucleotide analogue that is used as a probe for mapping RNA sequences and as an inhibitor of bacterial growth. This compound is also used in the synthesis of oligodeoxynucleotides because it has a high affinity for guanine residues, which can be incorporated into the oligonucleotide chain by chemical ligation. The octameric form of 7-deaza-2'-deoxyadenosine is most active against bacterial cells.Formula:C11H13IN4O3Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:376.16 g/mol1-(2',3',5'-Tri-O-acetyl-b-D-arabinofuranosyl)uracil
1-(2',3',5'-Tri-O-acetyl-b-D-arabinofuranosyl)uracil is a novel nucleoside analog with antiviral and anticancer activities. It is a modified nucleoside that is synthesized from 2',3',5'-triacetyl b-D-arabinofuranosyl uracil. The synthesis of this compound involves the use of acetylation, which produces a monophosphate form of the nucleoside. This product has been shown to be an activator in the synthesis of DNA and RNA.Purity:Min. 95%Inosine-3',5'-cyclic-monophosphate sodium
CAS:Inosine-3',5'-cyclic-monophosphate sodium (cIMP) is a metabolite of inosine and is generated by the enzyme inosine monophosphate cyclohydrolase. cIMP has been shown to be related to colorectal adenocarcinoma, cancer, and body mass index. It has also been implicated in the diagnosis of cancer and infectious diseases. cIMP is involved in energy metabolism and DNA synthesis, which are important for the progression of renal cell cancer. In addition, it has been shown that cIMP can function as a biomarker for prognosis when used with multivariate logistic regression.Formula:C10H11N4O7P·NaPurity:Min. 95%Molecular weight:353.18 g/molN4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a novel nucleoside, which is modified with a acetyl group and an O-methylation at the 2' position. It has been shown to inhibit tumor growth in vivo by inducing apoptosis and cell cycle arrest. N4-Acetyl-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite also has antiviral activity against HIV and can be used to activate transcription from RNA polymerase II promoters. This product is intended for research purposes only.Formula:C42H52N5O9PPurity:Min. 95%Color and Shape:White PowderMolecular weight:801.88 g/mol5'-O-(tert-Butyldimethylsilyl)thymidine, 97+%
CAS:5'-O-(tert-Butyldimethylsilyl)thymidine is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C16H28N2O5SiPurity:97+%Color and Shape:Powder, White to off-whiteMolecular weight:356.49Adenosine 5'-monophosphate sodium salt [1',2',3',4',5'-13C5]
Adenosine 5'-monophosphate sodium salt is a modified nucleoside that is used as an antiviral and an activator of the immune system. It also has been shown to have anti-inflammatory properties. Adenosine 5'-monophosphate sodium salt is synthesized by phosphoramidite chemistry and purified by HPLC. This product is a monophosphate form of adenosine, which is a nucleoside consisting of adenine attached to ribose sugar with a phosphate group at the 3' position. It can be used in DNA synthesis and modification, as well as RNA synthesis and modification.Purity:Min. 95%β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate
CAS:Please enquire for more information about β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C21H27N7NaO17P3Purity:Min. 95%Color and Shape:PowderMolecular weight:765.39 g/molGemcitabine base
CAS:Gemcitabine is a prodrug that is converted to 5-fluorouracil (5FU) in the body. It has been shown to inhibit the growth of bladder and pancreatic cancer cells by interfering with the synthesis of DNA. Gemcitabine inhibits DNA replication by binding to the epidermal growth factor receptor, which leads to cell death. Gemcitabine also acts as a competitive inhibitor of deoxycytidine kinase, which prevents the formation of deoxycytidine monophosphate from deoxyuridine monophosphate, preventing DNA replication. In addition, gemcitabine can activate apoptosis in some tumor cells by increasing levels of intracellular free calcium, which leads to activation of enzymes such as phospholipases and proteases that degrade proteins, lipids, and nucleic acids.Formula:C9H11F2N3O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:263.2 g/molThymidine-5'-diphosphate-L-rhamnose disodium
CAS:Thymidine-5'-diphosphate-L-rhamnose disodium is a nucleoside that belongs to the class of modified nucleosides. It is a synthetic, modified thymidine with a phosphate group at the 5'-position and L-rhamnose at the 2' position. Thymidine-5'-diphosphate-L-rhamnose disodium has antiviral and anticancer activities, as well as high purity and high quality. This compound has been shown to inhibit HIV replication in vitro and in vivo. Thymidine-5'-diphosphate-L-rhamnose disodium is also used in the synthesis of DNA and RNA.Formula:C16H24N2O15P2Na2Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:592.29 g/molAdenosine 5'-monophosphate [U-13C10,U-15N5]
CAS:Adenosine 5'-monophosphate (AMP) is a nucleoside that is used in the synthesis of DNA, RNA and other nucleic acids. AMP is also an antiviral and anticancer agent that can be used to activate other drugs. AMP is synthesized from adenosine triphosphate (ATP) by removing one phosphate group, resulting in the formation of adenosine diphosphate (ADP). ADP can then be converted to AMP by adding a phosphate group back on. This synthetic process can be modified to produce novel derivatives of AMP with enhanced properties.Formula:C10H14N5O7PPurity:Min. 95%Molecular weight:362.11 g/mol5’-O-DMT-N1-methylpseudouridine
CAS:5’-O-DMT-N1-methylpseudouridine is a monophosphate nucleoside that can be used for antiviral and anticancer purposes. This nucleoside has been shown to inhibit the synthesis of DNA and RNA, which may lead to apoptosis in cells infected by viruses. In addition, it has been shown to inhibit the proliferation of cancer cells by inhibiting protein synthesis. 5’-O-DMT-N1-methylpseudouridine is a novel nucleoside that is synthetically derived from uracil. The chemical structure of this product is different from other nucleosides because it contains a methyl group on the 5' hydroxyl group and an N1 methyl group on the 1'-hydroxyl group. This product is available in high purity and high quality.Purity:Min. 95%2'-Deoxy-7-deazaisoguanosine triphosphate
CAS:2'-Deoxy-7-deazaisoguanosine triphosphate is a nucleotide analogue that is used as an antiviral agent in the treatment of HIV. It has potent activity against HIV and other retroviruses, including SIV, FIV, and HTLV-1. 2'-Deoxy-7-deazaisoguanosine triphosphate has been shown to act as an activator of DNA polymerase by enhancing the incorporation of deoxynucleotide triphosphates into DNA. It also inhibits the synthesis of viral DNA by inhibiting the activity of reverse transcriptase enzymes. 2'-Deoxy-7-deazaisoguanosine triphosphate can be synthesized from diphosphates and phosphoramidites through a modified phosphoramidite approach that allows for high quality and purity with high yield.Formula:C11H17N4O13P3Purity:Min. 95%Molecular weight:506.19 g/molAlloxan hydrate
CAS:A pyrimidine derivative, widely used for the induction of diabetes in experimental animals. It preferentially accumulates in pancreatic β cells in Langerhans islets via glucose transporter GLUT2. In the presence of intracellular thiols such as glutathione, it gets involved in a cyclic redox reaction with its reduction product, dialuric acid. This triggers the production of toxic levels of reactive oxygen species (ROS) and directs the cells in necrosis. Alloxan also inhibits glucokinase, which regulates glucose-induced insulin secretion.Formula:C4H2N2O4•xH2OPurity:Min. 95%Molecular weight:142.07 g/mol5'-O-DMT-2'-O-methylguanosine
CAS:5'-O-DMT-2'-O-methylguanosine is a novel nucleoside analog that has been modified to contain the 2' methyl group at the 5' position. This modification enhances its anticancer activity and cellular uptake by cells. The 5'-O-DMT-2'-O-methylguanosine monophosphate synthesized in this study is chemically stable, high purity, and high quality.Formula:C32H33N5O7Purity:Min. 95%Molecular weight:599.65 g/mol