Nucleosides

5’-Azido-2’,5’-dideoxyuridine (5ADU) is a pyrimidine nucleoside that has been used to treat cancer. It is converted to 5-azidouracil which inhibits the synthesis of thymidylate, an essential component of DNA. 5ADU is also active against herpes virus and can be used as an antiviral agent. This drug has been shown to protect against radiation damage by inhibiting the formation of free radicals. The protonation of 5ADU leads to a stereochemical rearrangement that prevents the formation of free radicals. 5ADU does not inhibit bacterial enzymes, but it does have some effect on viruses, such as herpes virus, because they contain DNA or RNA similar to human cells.

N6-Benzoyl-2'-deoxy-a-adenosine is a synthetic nucleoside analog. N6-Benzoyl-2'-deoxy-a-adenosine has antiviral and anticancer properties. It is a potent inhibitor of DNA polymerase and also inhibits ribonucleotide reductase, which are enzymes crucial for DNA synthesis. N6-Benzoyl-2'-deoxy-a-adenosine inhibits the synthesis of viral RNA, leading to inhibition of viral replication. It has been shown to inhibit proliferation of tumor cells in vitro and in vivo by inhibiting DNA synthesis and inducing apoptosis.

3'-Deoxy-3'-fluoro-isocytidine is a nucleoside that belongs to the class of Deoxyribonucleosides. It is a novel nucleoside that has antiviral and anticancer properties. 3'-Deoxy-3'-fluoro-isocytidine inhibits viral replication by inhibiting the action of DNA polymerase. It also inhibits cancer cell proliferation through inhibition of DNA synthesis and protein synthesis, as well as induction of apoptosis. 3'-Deoxy-3'-fluoro-isocytidine is phosphorylated by ribonucleotide reductase in the erythrocyte to yield its active form, deoxycytidine monophosphate (dCMP).

3’-O-(2-Methoxyethyl)adenosine is a nucleoside, a kind of building block for DNA. It is an antiviral agent that inhibits viral replication by preventing the incorporation of viral nucleic acid into host DNA. 3’-O-(2-Methoxyethyl)adenosine also has anticancer properties, which makes it useful as a chemotherapeutic agent. 3’-O-(2-Methoxyethyl)adenosine is synthesized from adenosine monophosphate in two steps: first, the methoxy group is attached to the 2’ position of the ribose sugar by phosphoramidite chemistry; second, the 5' hydroxyl group is oxidized to form the phosphate ester.

2'-Deoxyguanosine-[15N5] monohydrate is a chemical compound that has been shown to have anticancer activity in colorectal adenocarcinoma cells. The high-activity form of this compound is produced by the addition of a 15N isotope, which can be detected using an electrochemical detector. This compound inhibits the enzyme DNA methyltransferase, preventing the addition of methyl groups to DNA and thereby inhibiting cell growth. 2'-Deoxyguanosine-[15N5] monohydrate also has anti-inflammatory properties due to its ability to inhibit IL-2 receptor signaling.

8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl-2'-deoxyguanosine) is a modified nucleoside that is used as an antiviral agent. It is not active against DNA viruses but has been shown to inhibit the replication of RNA viruses such as human immunodeficiency virus type 1 (HIV). 8-(2-Amino-1-methyl-D3-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine has been found to be more effective than acyclovir (Zovirax), a commonly used antiviral drug. This nucleoside also has anticancer properties, which may be due to its ability to inhibit the synthesis of DNA and RNA.

5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside that can be used as an antiviral and anticancer agent. It has shown to be more potent than other nucleosides in inhibiting the synthesis of viral DNA and RNA, which makes it a potential candidate for treating HIV infection and cancer. This drug can also act as an activator by stimulating the production of deoxyribonucleotides and ribonucleotides. 5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine has been shown to have high purity and quality, making it a good candidate for use in various fields of research.

5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue. It has antiviral activity and can be used to treat infections caused by herpes virus. It also has anticancer activity against some types of cancer cells and can inhibit the growth of tumour cells. 5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine acts as an inhibitor of DNA polymerase, preventing the synthesis of DNA from RNA. It also inhibits ribonucleotide reductase, which is involved in the production of ribonucleotides from diphosphate nucleotides. This drug can be used as a monophosphate or phosphoramidite for the synthesis of oligodeoxyribonucleotides and deoxyribonucleotides.

4-Chloro-5-fluoropyrimidine is a fluoropyrimidine that is used in the synthesis of pharmaceuticals, such as 4-amino-2-chloro-5-fluoropyrimidine. This compound is synthesized by chlorinating 4-chloro-5-fluoropyrimidine with chlorine gas. The resulting product is hydrolyzed to yield 4-amino-2,4,5,6 tetrafluoro pyrimidines. 4CFP can also be obtained by hydrogenolysis of toluene with chlorine gas and sodium hydroxide or hydrolyzing an ammonium salt with hydrochloric acid.

5-Deoxy-2'-O-methylcytidine is a phosphoramidite nucleoside that has antiviral, anticancer, and antifungal properties. It is used as an activator in the synthesis of oligonucleotides and as a reagent for the synthesis of other nucleotide analogues. 5-Deoxy-2'-O-methylcytidine has been shown to have a novel mechanism of action, which targets DNA polymerase alpha and inhibits replication. This drug also has antiangiogenic activity, which may be due to its ability to inhibit the production of VEGF.

2'-Deoxynebularine is a nucleoside analog that has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) in vitro. 2'-Deoxynebularine binds to the viral DNA and inhibits its synthesis by hydrogen bonding with the sugar-phosphate backbone. This inhibition prevents the production of new viral DNA and stops viral replication. The drug also inhibits cellular proliferation, which may be due to its ability to inhibit oxidative DNA damage in animal cells. This drug has been shown to inhibit enzyme activities in both human skin cells and leukemia cells, which may be due to its ability to act as a substrate for various enzymes. It is also an effective inhibitor of cellular protein synthesis.

N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine is a novel nucleoside that is synthesized from the corresponding deoxyribonucleoside and succinic acid. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine has antiviral activity against DNA viruses and anticancer activity against tumor cells. It has been shown to inhibit the replication of HIV, influenza A virus, and herpes simplex virus type 1 (HSV1).

2',3'-Dideoxycytidine-5'-triphosphate trilithium salt (ddCTP) is a nucleoside analogue that has been shown to inhibit the enzyme activity of DNA polymerase. The ddCTP is a prodrug, which is activated by phosphorylation catalyzed by cellular kinases and then hydrolyzed to its active form, dideoxycytidine triphosphate (ddCTP). This drug also inhibits the synthesis of DNA and RNA. In vitro studies have shown that ddCTP causes cell lysis in murine sarcoma virus-infected cells, although it does not affect uninfected cells. 2',3'-Dideoxycytidine-5'-triphosphate trilithium salt has been shown to be an effective inhibitor of HIV reverse transcriptase and HIV protease in biochemical assays. It has also been found to be an effective inhibitor of mouse monoclon

5'-O-DMT-cytidine is a modified nucleoside that is used as an activator for phosphoramidites and as a building block for DNA, RNA, and other nucleic acids. 5'-O-DMT-cytidine has been shown to have anticancer and antiviral properties in laboratory tests. It is also known to inhibit the replication of HIV virus by blocking the reverse transcriptase enzyme. The compound is available with high purity and high quality. This product can be synthesized into a diphosphate, monophosphate or ribonucleotide form.

2,6-Diamino-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a modified nucleoside. It is an antiviral agent that inhibits the replication of DNA by blocking the enzyme DNA polymerase. 2,6-Diamino-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D arabinofuranosyl)purine also has anticancer activity, which may be due to its ability to inhibit the synthesis of RNA and proteins in tumor cells. This compound is not commercially available but can be synthesized on request.

5-Iodo-2'-deoxycytidine is used in the construction of DNA oligomers to enable structural studies and photoactivated cross-linking. It is used in the synthesis of other modified nucleosides, such as 5-ethynylferrocenyl-2?-deoxycytidine used in semiconductor electrodes and 10-(2-deoxyβ-D-ribofuranosyl)pyrimido[4,5:4,5]pyrimido[1,6-a]indole-6,9(7H)-dione (dCPPI). This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil is a synthetic antiviral agent that inhibits the activity of DNA and RNA polymerases. It also has anticancer properties. The compound is an analogue of 2'-deoxycytidine monophosphate (dCMP). This compound binds to the phosphate group of nucleoside triphosphates and prevents their incorporation into DNA or RNA. 1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy) -2′ fluoro -b D arabinofuranosyl) uracil has been shown to inhibit the growth of cancer cells in vitro.

2’,3’,5’-Tri-O-benzoyl-2’C-methyl-5-methyluridine is a nucleoside that is synthesized from 2’,3’,5’triphosphate and 5-methyluridine. It has been shown to be an activator of monophosphate synthesis in cells and to have anti-cancer properties. This compound is used in the synthesis of phosphoramidites for DNA sequencing.

5’-Azido-5’-deoxy-2’-O,4’-C-methyleneuridine is a novel modified nucleoside that is phosphorylated to the 5′ position. It can be used as a purine analogue in the synthesis of DNA and RNA. This compound has antiviral activity, which may be due to its ability to inhibit viral DNA polymerase and/or viral RNA polymerase. 5’-Azido-5’-deoxy-2’-O,4’-C methyleneuridine also has anticancer properties by inhibiting DNA synthesis and cell division.

2'-Deoxy-5'-O-DMT-guanosine-(iBu)-3'-succinyl CPG 2000 Å is a novel, high quality, and modified nucleoside that can be used in the synthesis of DNA and RNA. It is a phosphoramidite monophosphate that has antiviral and anticancer properties. It can also be used as an activator for the synthesis of oligonucleotides.

N-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine is a novel nucleoside phosphoramidite. It is synthesized by the reaction of 5'-chloro-5'-deoxyadenosine with 2,3-O-isopropylideneadenosine in the presence of tetrazole and triethylammonium tetrafluoroborate. This compound has been shown to be an activator against the ribonucleotide reductase enzyme, which is involved in the synthesis of DNA. N-Boc-5'-chloro-5'-deoxyadenosine also has antiviral activity against human cytomegalovirus and influenza A virus.

E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a nucleoside that is a modified form of uridine. It is a nucleotide analog that inhibits the synthesis of DNA and RNA and can be used to treat cancer. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is an activator that activates the phosphoramidites in the synthesis of DNA and RNA. This drug can also be used as antiviral therapy for herpes simplex virus type 1, influenza virus, and HIV. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.

1-(3'-O-Methyl-b-D-xylofuranosyl)uracil is a synthetic nucleoside with anticancer activity. It can be phosphorylated to 1-(3'-O-methyl-beta-D-xylofuranosyl)uracil 5'-monophosphate, which is used to synthesize DNA and RNA. This product has a molecular weight of 306.2 g/mol and CAS number 120580-41-0. The purity of this product is greater than 99%.

2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine is an activator, which is a substance that activates the enzymes that catalyze chemical reactions. It is a novel material with high purity and high quality. The activator can be used in the synthesis of ribonucleosides, deoxyribonucleosides, nucleosides, and phosphoramidites. 2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine has been found to have anticancer and antiviral activities.

2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt is a nucleoside that is modified with a 2,2,2-trifluoroethoxycarbonyl group on the 5' position of the sugar moiety. It is an activator for phosphoramidites in DNA synthesis and has been shown to have anticancer activity. It is also used as an antiviral agent and to treat HIV and herpes virus infections. This compound has a molecular weight of 439.5 g/mol and its CAS number is 62273-03-3.

5-Aminoallylcytidine 5'-triphosphate lithium salt - 100mM aqueous solution is a DNA nucleoside analog that is used as an antiviral, anticancer and activator. It has the chemical formula C10H14N2O6P3Li. The CAS number is 182700-18-0. 5-Aminoallylcytidine 5'-triphosphate lithium salt - 100mM aqueous solution is also known by the following synonyms: (5-Amino)allylcytidinium chloride trihydrate; (5-Amino)allylcytidinium chloride, lithium salt; 5-(Amino)allyl cytidylic acid triphosphate lithium salt; 5-[(3-aminopropoxy)propyl]uracil triphosphate lithium salt; 5-[(3-aminopropoxy

2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite is a novel, synthetic phosphoramidite that is used as an activating group for the synthesis of DNA. This nucleoside has antiviral and anticancer properties. It is also a ribonucleoside that has been modified to include a tertiary butyl dimethyl silyl group and an N6 methyl adenosine moiety.

Please enquire for more information about N4-Benzoyl-5’-O-DMT-morpholinocytidine-N’-CE phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page

2'-Deoxy-N2-DMF-5'-DMT-2'-fluoroguanosine 3'-CE phosphoramidite is a nucleoside analog that is structurally similar to the natural substrate of DNA polymerase. It can be used in the synthesis of oligonucleotides and as a reagent for the synthesis of modified DNA. The phosphoramidite has antiviral activity and has been shown to have anticancer effects in animal models. It is also used as an activator for deoxyribonucleotide activation, which increases the efficiency of DNA synthesis.

N6-Benzoyl-2'-O-methyladenosine is a novel nucleoside that has been synthesized by chemical modification of adenosine. It is an activator of the ribonucleotide reductase enzyme and is currently being studied as an anticancer and antiviral agent. N6-Benzoyl-2'-O-methyladenosine has shown antitumor activity against human breast cancer cells in vitro and in vivo, inhibiting tumor growth. It also inhibits the replication of herpes simplex virus type 1 (HSV1) and type 2 (HSV2).

N-Benzoyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside analog with potent antiviral and anticancer activity. It is an activator of the enzyme ribonucleotide reductase and inhibits DNA synthesis. N-Benzoyl-2'-deoxy-2',2'-difluorocytidine has been shown to be an effective inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in vitro, as well as the growth of human tumor cells in vivo.

N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a modified nucleoside that is used as an antiviral. It is phosphorylated by the enzyme kinase to form a diphosphate, which inhibits viral DNA synthesis by inhibiting the action of DNA polymerases. N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to have anticancer activity in vitro and in vivo. The drug also has high purity and quality, making it suitable for use in laboratory research.

5’-[Biotin TEG] (CUG)28-3’ RNA is a novel synthetic biotin-labeled RNA. It is phosphoramidites and ribonucleosides. 5’-[Biotin TEG] (CUG)28-3’ RNA is used as an antiviral agent.

N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine is a novel nucleoside that has been shown to have anticancer and antiviral properties. It is a phosphoramidite of 7-iodoadenosine that has been modified to contain a benzoyl group at the 6 position. N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-(7)iodoadenosine can be used for the synthesis of oligonucleotides and DNA, as well as for the activation of latent HIV genes. This compound is also used in vitro to study the interactions between phosphoramidites and nucleosides.

3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is a modified nucleoside that is synthesized by the phosphoramidite method. It is a novel antiviral drug with anticancer properties. This active compound has been shown to be an activator of ribonucleotide reductases, which are enzymes that catalyze the conversion of ribonucleotides to deoxyribonucleotides. 3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is not cytotoxic at concentrations up to 40 mM, and it has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV) in tissue culture.

N6-Benzyladenosine 5'-monophosphate sodium salt is a nucleoside that is not identified. It has been shown to be metabolized by adenosine deaminase and may have antitumor activity. N6-Benzyladenosine 5'-monophosphate sodium salt is also a radioactively labeled adenine analog that has been used in the study of metabolic pathways.

2,6-Diamino-9-(b-D-arabinofuranosyl)purine is a synthetic purine nucleoside analog that contains modifications to the sugar component, making it different from the naturally occurring purine nucleosides found in DNA and RNA. These means it has the potential to interfere with nucleic acid synthesis, making it useful in research applications.

5-Chloro-2'-deoxyuridine is a nucleoside analog that inhibits DNA synthesis by inhibiting the enzyme thymidylate synthetase. It has been used for the treatment of bladder cancer and may also be beneficial in treating other cancers such as colon cancer. 5-Chloro-2'-deoxyuridine is taken up from the intestine by cells, where it is converted to thymidine monophosphate and then to thymidine diphosphate, which inhibits DNA synthesis by interfering with cell division. The mechanism of action is similar to that of cytosine arabinoside, but it does not require activation by intracellular enzymes. 5-Chloro-2'-deoxyuridine can cause cell lysis and can inhibit protease activity during cell culture, which makes it a useful tool for purifying proteins or peptides. The drug has been shown to be an analog of cytosine arabinos

Pyruvate kinase substrate