Nucleosides

N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine is a novel nucleoside that has been shown to have anticancer and antiviral properties. It is a phosphoramidite of 7-iodoadenosine that has been modified to contain a benzoyl group at the 6 position. N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-(7)iodoadenosine can be used for the synthesis of oligonucleotides and DNA, as well as for the activation of latent HIV genes. This compound is also used in vitro to study the interactions between phosphoramidites and nucleosides.

N-Benzoyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside analog with potent antiviral and anticancer activity. It is an activator of the enzyme ribonucleotide reductase and inhibits DNA synthesis. N-Benzoyl-2'-deoxy-2',2'-difluorocytidine has been shown to be an effective inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in vitro, as well as the growth of human tumor cells in vivo.

N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a modified nucleoside that is used as an antiviral. It is phosphorylated by the enzyme kinase to form a diphosphate, which inhibits viral DNA synthesis by inhibiting the action of DNA polymerases. N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to have anticancer activity in vitro and in vivo. The drug also has high purity and quality, making it suitable for use in laboratory research.

5’-[Biotin TEG] (CUG)28-3’ RNA is a novel synthetic biotin-labeled RNA. It is phosphoramidites and ribonucleosides. 5’-[Biotin TEG] (CUG)28-3’ RNA is used as an antiviral agent.

3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is a modified nucleoside that is synthesized by the phosphoramidite method. It is a novel antiviral drug with anticancer properties. This active compound has been shown to be an activator of ribonucleotide reductases, which are enzymes that catalyze the conversion of ribonucleotides to deoxyribonucleotides. 3'-b-Azido-2',3'-dideoxy-5'-O-DMT-uridine is not cytotoxic at concentrations up to 40 mM, and it has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV) in tissue culture.

N6-Benzyladenosine 5'-monophosphate sodium salt is a nucleoside that is not identified. It has been shown to be metabolized by adenosine deaminase and may have antitumor activity. N6-Benzyladenosine 5'-monophosphate sodium salt is also a radioactively labeled adenine analog that has been used in the study of metabolic pathways.

2,6-Diamino-9-(b-D-arabinofuranosyl)purine is a synthetic purine nucleoside analog that contains modifications to the sugar component, making it different from the naturally occurring purine nucleosides found in DNA and RNA. These means it has the potential to interfere with nucleic acid synthesis, making it useful in research applications.

5-Chloro-2'-deoxyuridine is a nucleoside analog that inhibits DNA synthesis by inhibiting the enzyme thymidylate synthetase. It has been used for the treatment of bladder cancer and may also be beneficial in treating other cancers such as colon cancer. 5-Chloro-2'-deoxyuridine is taken up from the intestine by cells, where it is converted to thymidine monophosphate and then to thymidine diphosphate, which inhibits DNA synthesis by interfering with cell division. The mechanism of action is similar to that of cytosine arabinoside, but it does not require activation by intracellular enzymes. 5-Chloro-2'-deoxyuridine can cause cell lysis and can inhibit protease activity during cell culture, which makes it a useful tool for purifying proteins or peptides. The drug has been shown to be an analog of cytosine arabinos

Pyruvate kinase substrate