Complement System
The complement system is a crucial part of the immune response, consisting of a series of small proteins that enhance the ability of antibodies and phagocytic cells to clear pathogens from an organism. These proteins work together to opsonize pathogens, induce inflammatory responses, and directly lyse pathogen membranes, playing a vital role in innate immunity and overall immune function. At CymitQuimica, we provide high-quality complement system proteins to support your immunological studies and clinical research.
Products of "Complement System"
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C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated
C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated is expressed in E. coli with N-MBP, C-6xHis-Avi. The accession number is P30993.Color and Shape:Lyophilized PowderMolecular weight:52.8 kDa (Predicted)W-54011
CAS:W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Formula:C30H37ClN2O2Purity:95.62%Color and Shape:SolidMolecular weight:493.08Ref: TM-T17250
1mg85.00€5mg127.00€10mg187.00€25mg335.00€50mg518.00€100mg747.00€1mL*10mM (DMSO)165.00€C1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Formula:C16H22Cl3N5Color and Shape:SolidMolecular weight:390.74C5aR2 agonist P32 acetate
C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.Formula:C54H70N16O11·xC2H4O2Color and Shape:SolidMolecular weight:1119.23 (free base)Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formula:C22H15NO4S2Purity:98% - 98.49%Color and Shape:SolidMolecular weight:421.49Iptacopan hydrochloride
CAS:Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.Formula:C25H31ClN2O4Purity:98.32% - 99.87%Color and Shape:SolidMolecular weight:458.98Ref: TM-T9189
1mg59.00€5mg127.00€10mg205.00€25mg371.00€50mg620.00€100mg1,026.00€200mg1,388.00€1mL*10mM (DMSO)128.00€C3a (70-77)
CAS:C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.Formula:C35H61N13O10Purity:98%Color and Shape:SolidMolecular weight:823.94Danicopan
CAS:Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.Formula:C26H23BrFN7O3Purity:99.94%Color and Shape:SolidMolecular weight:580.41Ref: TM-T8509
1mg96.00€2mg136.00€5mg215.00€10mg328.00€25mg557.00€50mg797.00€100mg1,103.00€1mL*10mM (DMSO)274.00€MASP2 Protein, Human, Recombinant (His)
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.Color and Shape:Lyophilized PowderMolecular weight:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.C1QL1 Protein, Mouse, Recombinant (His)
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.Color and Shape:Lyophilized PowderMolecular weight:26.9 kDa (predicted)(Rel)-Factor B-IN-5
CAS:(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.Formula:C27H32N2O4Purity:98.53%Color and Shape:SolidMolecular weight:448.55Complement C3 Protein, Mouse, Recombinant (His)
Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:36.34 kDa (predicted); 32.39 kDa (reducing conditions)Greziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Color and Shape:Odour LiquidCR1 Protein, Human, Recombinant
CR1 Protein, Human, Recombinant is expressed in E. coli with Tag Free. The accession number is P17927.Color and Shape:Lyophilized PowderMolecular weight:21.6 kDa (Predicted)Complement factor B Protein, Mouse, Recombinant (His)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.Color and Shape:Lyophilized PowderMolecular weight:87.0 kDa (predicted)Cyclosporin A
CAS:Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Formula:C62H111N11O12Purity:99.00% - 99.85%Color and Shape:White PowderMolecular weight:1202.61C1q Protein (human)
C1qProtein (human) serves as a subunit in the complement system. It binds to a variety of ligands from self, non-self, and altered-self, contributing to the balance of the immune system, promoting tissue repair, and defending against pathogens.Formula:C19H24N4O3SColor and Shape:SolidMolecular weight:388.48Complement Factor D/CFD Protein, Human, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Color and Shape:Lyophilized PowderMolecular weight:51.2 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.C1QB Protein, Human, Recombinant (His)
Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system.Color and Shape:Lyophilized PowderMolecular weight:25.2 kDa (predicted); 30 kDa (reducing condition, due to glycosylation)Complement C5 Protein, Cynomolgus, Recombinant (His)
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:188.1 kDa (predicted); 106.3 and 75.8 kDa (reducing conditions)
