Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Products of "Ketones and derivatives"
Sort by
Alphaprodine Hydrochloride
CAS:Controlled ProductStability Hygroscopic Applications Analgesic (narcotic). Controlled substance (opiates). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Gruber, G.M., et al.: J. Pharmacol. Exp. Ther., 99, 312 (1950), Abdel-Monem, M.M., et al.: J. Med. Chem., 15, 494 (1972),Formula:C16H23NO2·ClHColor and Shape:Off-WhiteMolecular weight:297.82Acetylsalicylic Acid
CAS:Applications Analgesic; antipyretic; anti-inflammatory; antithrombotic. Acetylsalicylic acid has also been shown to prevent or inhibit tumour growth, including in cervical, colorectal, lung brest, colon, pancreas, prostate and many other cancers. Aspirin is widely used as an anti-inflammatory drug. It has been shown to prevent or inhibit tumor growth, including in cervical, colorectal, lung, breast, colon, pancreas, prostate, and many other types of cancer. References Hart, E.R., et al.: J. Pharmacol. Exp. Ther., 89, 205 (1947); Florey, K., et al.: Anal. Profiles Drug Subs., 8, 1 (1979); AAPS Newsmagazine, p. 17 July 2016;Formula:C9H8O4Color and Shape:WhiteMolecular weight:180.16Diclofenac acid
CAS:Controlled ProductFormula:C14H11Cl2NO2Color and Shape:NeatMolecular weight:296.15Ibuprofen-13C6
CAS:Applications Labelled Ibuprofen, a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),Formula:C713C6H18O2Color and Shape:NeatMolecular weight:212.24Ref: 4Z-M-6888
Discontinued product1-[4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]ethanone
CAS:Purity:95.0%Molecular weight:308.303985595703110-Oxo Naltrexone Methyl Ether
CAS:Controlled ProductApplications Naltrexone derivative, showing significantly less potency than pure Naltrexone. References Archer, S., et al.: J. Med. Chem., 28, 974 (1985),Formula:C21H23NO5Color and Shape:NeatMolecular weight:369.411-{3-[(diethylamino)methyl]-4-hydroxyphenyl}ethan-1-one hydrochloride
CAS:Purity:98%Molecular weight:257.7600097656252',4',6'-Trifluoroacetophenone
CAS:Purity:97.0%Color and Shape:LiquidMolecular weight:174.12199401855471-(4-(Benzyloxy)-6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one
CAS:Purity:97%Molecular weight:302.32598876953125Romifidine-d4 Hydrochloride
CAS:Controlled ProductFormula:C9H6D4BrClFN3Color and Shape:NeatMolecular weight:298.584,5alpha-Epoxy-3-methoxy-17-methylmorphinan-6beta,14-diol Hydrochloride (6beta-Oxycodol Hydrochloride)
Controlled ProductFormula:C18H23NO4·HClFirocoxib-d4
CAS:Controlled ProductApplications Labelled Firocoxib (F356002). A selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory; analgesic. References McCann, M.E., et al.: Am. J. Vet. Res., 65, 503 (2004),Formula:C172H4H16O5SColor and Shape:NeatMolecular weight:340.43Ketoprofen-13C-d3
CAS:Formula:C1513CH11D3O3Color and Shape:White To Off-White SolidMolecular weight:258.30(R)-Naproxen
CAS:Controlled ProductFormula:C14H14O3Color and Shape:White To Off-WhiteMolecular weight:230.261-(3-Bromo-4-(1H-pyrazol-1-yl)phenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:265.1099853515625(R)-Naproxen Acyl-Beta-D-glucuronide
CAS:Controlled ProductStability Hygroscopic Applications A metabolite of Naproxen. References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Jin, C., et al.: J. Pharmacol. Exp. Ther., 264, 475 (1993),King, C., et al.: Toxicol. Sci., 61, 49 (2001), Aresta, A., et al.: J. Pharm. Biomed. Anal., 39, 643 (2005),Formula:C20H22O9Color and Shape:NeatMolecular weight:406.382,6-Dichloroaniline
CAS:Controlled ProductFormula:C6H5Cl2NColor and Shape:NeatMolecular weight:162.024-[5-[4-(Hydroxymethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
CAS:Formula:C17H14F3N3O3S1-(2-Hydroxy-6-methylphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:150.1770019531252',5'-Dihydroxyacetophenone
CAS:Purity:98.0%Color and Shape:Solid, CrystallineMolecular weight:152.14900207519531,1'-(1,4-Phenylene)diethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:162.188003540039063-(4-Acetylphenyl)-2-aminopropanoic acid hydrochloride
CAS:Purity:95.0%Molecular weight:243.69000244140625(2RS)-2-[4-(2-Methyl-propanoyl)phenyl]propanoic Acid
CAS:Controlled ProductFormula:C13H16O3Color and Shape:NeatMolecular weight:220.26(3R)-3-Hydroxy Quinine
Formula:C20H24N2O3Color and Shape:White To Off-White SolidMolecular weight:340.43Dexmedetomidine-13C-d3 HCl
CAS:Formula:C1213CH13D3N2·HClColor and Shape:White To Off-White SolidMolecular weight:204.30 36.46Ref: 4Z-M-6890
Discontinued productColumbin
CAS:Controlled ProductApplications Columbin is a furanolactone diterpene isolated from the roots of Jateorhiza and Tinospora species and is used in Asian and African folk medicine for analgesic and antipyretic properties. References Yilmaz, A. et al.: J. Nat. Prod., 80, 2094 (2017);Formula:C20H22O6Color and Shape:NeatMolecular weight:358.395-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole
CAS:Controlled ProductFormula:C13H14N2Color and Shape:NeatMolecular weight:198.265'-Fluoro-2'-methylacetophenone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:152.167999267578124'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:294.30700683593751-Methylethyl 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide
CAS:Formula:C13H15NO5S4'-Chloroacetanilide
CAS:Controlled ProductApplications 4′-Chloroacetanilide is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3,4). References (1) Călinescu, O., et al.: J. Chromatogr. Sci. 50(4), 335-42, (2012)(2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)Formula:C8H8ClNOColor and Shape:Light BrownMolecular weight:169.61N-Acetyl-4-benzoquinone Imine-D3
CAS:Controlled ProductStability Temperature, Moisture, Light, and Oxygen Sensitive Applications N-Acetyl-4-benzoquinone imine-D3 is deuterium labeled N-Acetyl-4-benzoquinone Imine (A170000). N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). N-Acetyl-4-benzoquinone Imine can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (A161255) (4). References (1) Jaeschke, H., et al.: Toxicol. Sci., 89, 31 (2006) (2) O’Malley G. F., et al.: J Med Toxicol. 11, 317 (2015)(3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(4) Frey, S. M., et al.: J Med Toxicol. 11, 218 (2015)Formula:C8H4D3NO2Color and Shape:Yellow To BrownMolecular weight:152.17Metamizole Sodium Monohydrate 1.0 mg/ml in Dimethyl Sulfoxide (as anhydrous free acid)
CAS:Formula:C13H16N3O4S·Na·H2ON-Methyl-1H-indole-5-ethanesulfonamide (2-(1H-Indol-5-yl)-N-methylethanesulfonamide)
CAS:Formula:C11H14N2O2S1-(2-Fluoro-5-hydroxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:154.139999389648443-Hydroxyacetaminophen-D3
CAS:Controlled ProductApplications 3-Hydroxyacetaminophen-d3 is deuterium labeled 3-Hydroxyacetaminophen (H714750). 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)Formula:C8H3H6NO3Color and Shape:NeatMolecular weight:170.182'-Iodoacetophenone
CAS:Purity:98.0%Color and Shape:Liquid, Clear Colourless to YellowMolecular weight:246.04699707031253-Acetyl-2,6-difluorobenzoic acid
CAS:Purity:98%Color and Shape:SolidMolecular weight:200.141006469726561-(5-Amino-2-fluorophenyl)ethanone
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:153.1560058593751,1'-(2-Hydroxy-5-methyl-1,3-phenylene)diethanone
CAS:Purity:95.0%Molecular weight:192.214004516601561,6-Dehydro Tramadol Hydrochloride (1-(3-Methoxyphenyl)-2-(dimethylaminomethyl) cyclohex-6-ene hydrochloride)
CAS:Amino-naphthols and other amino-phenols, their ethers and esters, other than those cont more than one kind of oxygen function; salts thereof, nesoiFormula:C16H23NO·HClColor and Shape:White PowderMolecular weight:245.177961-[3,5-dimethyl-4-(4-nitrophenoxy)phenyl]ethanone
CAS:Purity:95.0%Molecular weight:285.299011230468752'-Fluoro-6'-methoxyacetophenone
CAS:Purity:98.0%Color and Shape:LiquidMolecular weight:168.16700744628906Methyl Acetylsalicylate
CAS:Controlled ProductFormula:C10H10O4Color and Shape:NeatMolecular weight:194.18Acetaminophen (Paracetamol)
CAS:Formula:C8H9NO2Color and Shape:White To Off-White SolidMolecular weight:151.172'-(Trifluoromethyl)propiophenone
CAS:Purity:97.0%Color and Shape:LiquidMolecular weight:202.17599487304688Acetaminophen Acetate (Acetaminophen Impurity)
CAS:Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)Formula:C10H11NO3Color and Shape:White To Off-WhiteMolecular weight:193.20Properidine (1-Methylethyl 1-Methyl-4-phenyl-piperidine-4-carboxylate)
CAS:Controlled ProductFormula:C16H23NO2Dextromethorphan-d3
CAS:Controlled ProductFormula:C182H3H22NOColor and Shape:Off-WhiteMolecular weight:274.421-(2-Hydroxy-4-methoxyphenyl)ethanone
CAS:Purity:99.00%Color and Shape:SolidMolecular weight:166.17599487304688Nalbuphine Hydrochloride
CAS:Controlled ProductFormula:C21H27NO4·ClHColor and Shape:NeatMolecular weight:393.902-Fluorobiphenyl-4-carboxylic Acid
CAS:Controlled ProductImpurity Flurbiprofen impurity Applications 2-Fluorobiphenyl-4-carboxylic Acid is an impurity of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic. Flurbiprofen impurity E. References Andersen, K., et al.: Neurology, 45, 1441 (1995); Aldini, G., et al.: Life Sci., 71, 1487 (2002); Chao, S., et al.: Biol. Pharmaceut. Bull., 28, 2206 (2005);Formula:C13H9FO2Color and Shape:NeatMolecular weight:216.21N-(4-Acetylphenyl)methanesulfonamide
CAS:Purity:95.0%Color and Shape:Solid, Beige powderMolecular weight:213.256'-Methoxy-2'-acetonaphthone (Naproxen Impurity L)
CAS:Controlled ProductImpurity Naproxen USP Related Compound L Applications Naproxen impurity L. Naproxen USP Related Compound L References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Li, J., et al.: J. Med. Chem., 39, 1846 (1996), Monser, L., et al.: J. Pharm. Biomed. Anal., 27, 851 (2002),Formula:C13H12O2Color and Shape:BeigeMolecular weight:200.2333-Fluoro-4-methoxyacetophenone
CAS:Purity:98.0%Color and Shape:SolidMolecular weight:168.16700744628906Pelubiprofen-13C-d3
CAS:Formula:C1513CH15D3O3Color and Shape:White To Off-White SolidMolecular weight:262.33Tert-butyl (4-acetylphenyl)carbamate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:235.28300476074222'-Fluoro-5'-(trifluoromethyl)propiophenone
CAS:Purity:97.0%Color and Shape:LiquidMolecular weight:220.16700744628906Medetomidine Impurity 36
CAS:Formula:C31H28N2OColor and Shape:White To Off-White SolidMolecular weight:444.584-[5-(3-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
CAS:Formula:C17H14F3N3O2S1-(2-Fluoro-4-methylphenyl)ethanone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:152.16799926757812Dexmedetomidine USP Related Compound B
CAS:Formula:C13H14N2Color and Shape:White To Off-White SolidMolecular weight:198.27Ref: 4Z-M-6812
Discontinued product3-Acetylphenyl ethyl(methyl)carbamate
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:221.255996704101564'5'-Dimethyl-2'-hydroxyacetophenone
CAS:Purity:99.0%Color and Shape:Solid, No data available.Molecular weight:164.203994750976561-(4-Bromo-2-chlorophenyl)ethanone
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:233.49000549316406Trimebutine-d5 Fumarate
CAS:Formula:C22H24D5NO5·C4H4O4Color and Shape:White To Off-White SolidMolecular weight:392.51 116.07(2-Methoxy-2-oxoethyl) 2-(5-Methoxy-2-methyl-1H-indol-3-yl)acetate
Formula:C15H17NO5Color and Shape:Neat4-[(1RS)-1,3-Dimethylbutyl]-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
CAS:Color and Shape:NeatMedetomidine Impurity 65
Formula:C13H14N2OColor and Shape:White To Off-White SolidMolecular weight:214.275-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic (5BPC) is a drug that is used for the treatment of pain. It has been shown to be safe and effective in treating postoperative pain when given by intravenous infusion or as an oral tablet. 5BPC has minimal toxicity and is metabolized primarily by the liver with a half life of 2.6 hours. The drug has been found to have pharmacokinetic properties that allow it to be used safely in patients with hepatic impairment and in those recovering from abdominal surgery. 5BPC is a prodrug that undergoes biotransformation by esterases into its active form, pyrrolizidine alkaloid (PA). PA acts as a nonsteroidal anti-inflammatory agent and inhibits prostaglandin synthesis, which leads to analgesia. This drug also has minimal drug interactions becauseFormula:C15H13O3NPurity:Min. 95%Molecular weight:255.27 g/mol4,5-Dimethyl-2-methoxyacetophenone
CAS:Purity:95.0Color and Shape:SolidMolecular weight:178.2310028076172Ketorolac EP Impurity G
CAS:Formula:C16H15NO4Color and Shape:White To Off-White SolidMolecular weight:285.30Benzothiazole-d4
CAS:Controlled ProductApplications Labelled Benzothiazole. Various benzothiazole-benzamides synthesized were evaluated for their analgesic and antidepressant activities. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Porsolt, R., et al.: Nature, 266, 730 (1977), Foster, J., et al.: Bioorg. Med. Chem., 7, 2415 (1999), Caliendo, G., et al.: Eur. J. Med. Chem., 36, 517 (2001), Rana, A., et al.: Eur. J. Med. Chem., 43, 1114 (2008),Formula:C7HD4NSColor and Shape:Colourless To Dark BrownMolecular weight:139.211-(2-Bromo-4-hydroxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:215.04600524902344Cyclohexanone, 99+%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C6H10OPurity:99+%Color and Shape:Clear liquidMolecular weight:98.151-(2-METHYL-4-(TRIFLUOROMETHYL)PHENYL)ETHAN-1-ONE
CAS:Purity:95.0%Molecular weight:202.175994873046884-Acetyl-2-fluorobiphenyl
CAS:Applications 4-Acetyl-2-fluorobiphenyl is an impurity of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic. Flurbiprofen impurity D. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Andersen, K., et al.: Neurology, 45, 1441 (1995); Aldini, G., et al.: Life Sci., 71, 1487 (2002); Chao, S., et al.: Biol. Pharmaceut. Bull., 28, 2206 (2005);Formula:C14H11FOColor and Shape:White To Light YellowMolecular weight:214.231-(2-Hydroxy-5-(trifluoromethyl)phenyl)ethanone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:204.1479949951172Codeine-d6
CAS:Controlled ProductFormula:C182H6H15NO3Color and Shape:Off-WhiteMolecular weight:305.401-(4-(aminomethyl)phenyl)ethan-1-one hydrobromide
CAS:Purity:95.0%Molecular weight:230.10499572753906
![1-[4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]ethanone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF070543.webp&w=3840&q=75)
![1-{3-[(diethylamino)methyl]-4-hydroxyphenyl}ethan-1-one hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF645893.webp&w=3840&q=75)
![6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F4Z%2Fthumb-webp%2FC-249007.webp&w=3840&q=75)
![(2RS)-2-[4-(2-Methyl-propanoyl)phenyl]propanoic Acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb-webp%2FMM0002.02.webp&w=3840&q=75)
![5-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD476965.webp&w=3840&q=75)
![1-[3,5-dimethyl-4-(4-nitrophenoxy)phenyl]ethanone](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF368207.webp&w=3840&q=75)
![4-[(1RS)-1,3-Dimethylbutyl]-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb-webp%2FMM0036.04-0025.webp&w=3840&q=75)
![2-[4-(2-Methylpropenyl)phenyl]propionic Acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb-webp%2FMM0002.66-0025.webp&w=3840&q=75)
![1-[4-(pyridin-4-yl)phenyl]ethan-1-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF675880.webp&w=3840&q=75)
