Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Products of "Ketones and derivatives"
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2,5-Dimethoxyacetophenone
CAS:Purity:98.0%Color and Shape:Solid, Low Melting SolidMolecular weight:180.2030029296875Diclofenac sodium
CAS:Controlled ProductFormula:C14H10Cl2NO2·NaColor and Shape:NeatMolecular weight:318.134-Acetaminophen-d3 Sulfate
CAS:Controlled ProductApplications 4-Acetaminophen-d3 Sulfate is deuterium labeled metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent (1,2,3). References (1) Lloyd, A., et al.: Biochim. Biophys. Acta., 52, 413 (1961) (2) Purohit, A., et al.: J. Steroid Biochem. Mol. Biol., 86, 423 (2003) (3) Winum, J., et al.: J. Med. Chem., 46, 2197 (2003)Formula:C82H3H6NO5SColor and Shape:White To Off-WhiteMolecular weight:234.24Basic Butylated Methacrylate Copolymer EP Impurity A (Butyl Methacrylate)
CAS:Formula:C8H14O2Color and Shape:Colorless LiquidMolecular weight:142.20(-)-Butorphanol-d6
CAS:Controlled ProductStability Hygroscopic Applications Labelled Butorphanol (B690550). Mixed opioid agonist-antagonist. Analgesic (narcotic); antitussive. Controlled substance. References Vargas-Arreola, F., et al.: Curr. Ther. Res., 22, 186 (1977), Heel, R.C., et al.: Drugs, 16, 473 (1978),Formula:C21H23D6NO2Color and Shape:Off-WhiteMolecular weight:333.53'-(Trifluoromethyl)acetophenone
CAS:Purity:99.0%Color and Shape:Liquid, ClearMolecular weight:188.1490020751953rac 2-(tert-Butyldimethylsilyloxy)-Alpha-desmethyl Ibuprofen-d6 tert-Butyldimethylsily Ester
Controlled ProductApplications 2-Hydroxy Ibuprofen-d6 (H942862) derivative.Formula:C24H38D6O3Si2Color and Shape:NeatMolecular weight:442.817,7',8,8'-Tetradehydro-4,5α:4',5'α-diepoxy-3,3'-dimethoxy-17,17'-dimethyl-2,2'-bimorphinanyl-6α,6'α-diol (Codeine Dimer; Dimethyl Pseudomorphine)
CAS:Controlled ProductFormula:C36H40N2O6Color and Shape:NeatMolecular weight:596.71Acetaminophen Dimer (Paracetamol Dimer)
CAS:Formula:C16H16N2O4Color and Shape:White To Off-White SolidMolecular weight:300.31Methyl 2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetate (Methyl Ester of Diclofenac)
CAS:Formula:C15H13Cl2NO2Alphameprodine Hydrochloride
CAS:Controlled ProductApplications Narcotic analgesic. An analogue of Proline (P755300). References Iorio, M.A., et al.: J. Med. Chem., 20, 309 (1977),Formula:C17H26ClNO2Color and Shape:NeatMolecular weight:311.855-Ethyl-2-methoxyacetophenone
CAS:Purity:97%Color and Shape:Solid, No data available.Molecular weight:178.23100280761722',5'-Difluoropropiophenone
CAS:Purity:97.0%Color and Shape:LiquidMolecular weight:170.15899658203125(±)-2-Phenylpropanoic Acid
CAS:Applications Used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers. References Leeman, M. et al.: Angew. Chem. Int. Ed., 47, 1287 (2008); Eur. J. Med. Chem., 45, 3564 (2010);Formula:C9H10O2Color and Shape:Light Yellow LiquidMolecular weight:150.17Ketoprofen EP Impurity J Sodium Salt
Formula:C18H17O3·NaColor and Shape:White To Off-White SolidMolecular weight:281.33 22.99(R,R)-N-(1-Phenylethyl) Ibuprofen Amide
CAS:Controlled ProductApplications The (R,R)-enantiomer of Ibuprofen (I140000) impurity, an anti-inflammatory compound. References Rubin, A., et al.: J. Pharm. Sci., 74, 82 (1985), Tracy, T., et al.: Drug Metab. Dispos., 20, 322 (1992),Formula:C21H27NOColor and Shape:White To Off-WhiteMolecular weight:309.45Isopropyl 2-(3-Benzoylphenyl)propionate
CAS:Controlled ProductFormula:C19H20O3Color and Shape:NeatMolecular weight:296.36Medetomidine Impurity 38
CAS:Formula:C32H30N2OColor and Shape:White To Off-White SolidMolecular weight:458.61Nabumetone EP Impurity A
CAS:Controlled ProductFormula:C18H20O2Color and Shape:NeatMolecular weight:268.35[6]-Shogaol (>90%)
CAS:Controlled ProductApplications [6]-Shogaol is an aromatic constituent of ginger and the chain-dehydroxylated analog of [6]-Gingerol. [6]-Shogaol has activity very similar to [6]-Gingerol and produced an inhibition of spontaneous motor activity, antipyretic and analgesic effects, and prolonged hexobarbital-induced sleeping time. [6]-Shogaol also has potent antitussive activity and affected the cortical EEG. References Suekawa, M. et al.: J. Pharm-Dyn., 7, 836 (1984); Yoshikawa, M. et al.: Chem. Pharmac. Bull., 40, 2239 (1992);Formula:C17H24O3Purity:>90%Color and Shape:NeatMolecular weight:276.371-(4-Chloro-2-hydroxyphenyl)ethanone
CAS:Purity:97.0%Color and Shape:Solid, CrystallineMolecular weight:170.58999633789062Methyl 5-Acetyl-2-hydroxybenzoate
CAS:Purity:97.0%Color and Shape:Solid, White powderMolecular weight:194.18600463867188Pelubiprofen Impurity 8
CAS:Formula:C16H22O3Color and Shape:White To Off-White SolidMolecular weight:262.35Medetomidine Impurity 26 HCl
Formula:C13H16N2·HClColor and Shape:White To Off-White SolidMolecular weight:200.29 36.461-(4-(Bromomethyl)phenyl)ethanone
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:213.074005126953122'-Fluoro-4'-(trifluoromethyl)acetophenone
CAS:Purity:98.0%Color and Shape:LiquidMolecular weight:206.139999389648441-(3,4-Dimethylphenyl)ethanone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:148.2050018310547Ketoprofen Related Compound C (2-(3-carboxyphenyl)propionic acid)
CAS:Aromatic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids etc, nesoiFormula:C10H10O4Color and Shape:White PowderMolecular weight:194.05791(-)-O-Desmethyl-N,N-bisdesmethyl Tramadol
CAS:Applications A optically active metabolite of Tramadol. References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)Formula:C13H19NO2Color and Shape:NeatMolecular weight:221.34'-amino-3',5'-dichloroacetophenone
CAS:Purity:97.0%Color and Shape:Solid, CrystallineMolecular weight:204.05000305175781-(2-Fluoro-5-iodophenyl)ethan-1-one
CAS:Purity:97%Color and Shape:SolidMolecular weight:264.0379943847656Ketoprofen EP Impurity I
CAS:Formula:C15H11NOColor and Shape:White To Off-White SolidMolecular weight:221.26Ketoprofen EP Impurity L
CAS:Formula:C19H20O3Color and Shape:White To Off-White SolidMolecular weight:296.37Tapentadol N-Oxide
CAS:Controlled ProductApplications A metabolite of Tapentadol (T007200).Formula:C14H23NO2Color and Shape:PurpleMolecular weight:237.34Methyl 2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetate (Methyl Ester of Diclofenac)
CAS:Formula:C15H13Cl2NO2rac Ketoprofen
CAS:Controlled ProductApplications Anti-inflammatory; analgesic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),Formula:C16H14O3Color and Shape:NeatMolecular weight:254.283-Fluoro-4-methylacetophenone
CAS:Purity:97.0%Color and Shape:Solid, Low Melting SolidMolecular weight:152.16799926757812(+)-N,O-Didesmethyl Tramadol
CAS:Controlled ProductApplications An optically active metabolite of Tramadol. References Garrido, M., et al.: J. Pharmacol. Exp. Ther., 305, 710 (2003), Pedersen, R., et al.: Eur. J. Clin. Pharmacol., 62, 513 (2006),Formula:C14H21NO2Color and Shape:NeatMolecular weight:235.32Diclofenac sodium 100 µg/mL in Acetonitrile
CAS:Formula:C14H10Cl2NO2·NaColor and Shape:Single SolutionMolecular weight:318.13Sufentanil Citrate 0.1 mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C22H30N2O2S·C6H8O7Norfentanyl-D5 Oxalate (N-Pentadeuterophenyl-N-(piperidin-4-yl)propanamide Oxalate) 0.1 mg/ml in Methanol (as free base)
CAS:Controlled ProductFormula:C142H5H15N2O·C2H2O44’-Hydroxyacetophenone Oxime
CAS:Controlled ProductImpurity Paracetamol EP Impurity G Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)Formula:C8H9NO2Color and Shape:NeatMolecular weight:151.161,5-Bis(6-methoxynaphthalen-2-yl)pentan-3-one
CAS:Controlled ProductFormula:C27H26O3Color and Shape:NeatMolecular weight:398.493',4',5'-Trifluoroacetophenone
CAS:Purity:97.0%Color and Shape:Solid, Low Melting SolidMolecular weight:174.1219940185547Tramadol Related Compound A CIV ((RS,SR)-1-(3-Methoxyphenyl)-2-(dimethylaminomethyl)cyclohexanol hydrochloride)
CAS:Controlled ProductAromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen functionFormula:C16H25NO2·HClColor and Shape:White PowderMolecular weight:263.18853Meloxicam-d3
CAS:Controlled ProductApplications Labelled form of Meloxicam. Preferential cyclooxygenase (COX-2) inhibitor. Used as an anti-inflammatory. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Hawkey, C., et al.: Br. J. Rheumatol., 35, Suppl. 1, 1 (1996), Fleischmann, R., et al.: Expert Opin. Pharmacother., 3, 1501 (2002),Formula:C142H3H10N3O4S2Color and Shape:Light Yellow To YellowMolecular weight:354.421-(2-Amino-3-methoxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:165.19200134277344Medetomidine
CAS:Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.Formula:C13H16N2Purity:99.88%Color and Shape:SolidMolecular weight:200.28Nabumetone EP Impurity B
CAS:Controlled ProductFormula:C18H18O2Color and Shape:NeatMolecular weight:266.33N-(4-Hydroxyphenyl-2,3,5,6-d4)acetamide-2,2,2-d3
CAS:Controlled ProductApplications N-(4-Hydroxyphenyl-2,3,5,6-d4)acetamide-2,2,2-d3 is deuterium labelled form of Acetaminophen (A161220), which is analgesic and antipyretic drug. It is a pain reliever commonly used to treat headache, muscle aches, arthritis, and other acute or chronic painful conditions. References Roberts, E., et al.: Ann. Rheum. Dis., 75, 552 (2016);Formula:C8H2D7NO2Color and Shape:NeatMolecular weight:158.21Ref: 10-F365267
1gTo inquire2gTo inquire5gTo inquire10gTo inquire25gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire1-(3-Chloro-2-fluorophenyl)ethanone
CAS:Purity:97.0%Color and Shape:Liquid, No data available.Molecular weight:172.5800018310547Quinine hydrochloride dihydrate
CAS:Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.Formula:C20H24N2O2·HCl·2H2OPurity:99.04%Color and Shape:White To Light Yellow Crystal PowderMolecular weight:396.91Ketoprofen Tromethamine Amide
CAS:Formula:C20H23NO5Color and Shape:White To Off-White Stick SolidMolecular weight:357.41Pethidine EP Impurity D
CAS:Controlled ProductFormula:C14H19NO2Color and Shape:NeatMolecular weight:233.31Pelubiprofen
CAS:Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.Formula:C16H18O3Purity:99.69%Color and Shape:SolidMolecular weight:258.313-Hydroxyacetaminophen
CAS:Controlled ProductApplications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)Formula:C8H9NO3Color and Shape:NeatMolecular weight:167.16Tramadol Impurity 6 (Mixture of Diastereomers)
Formula:C16H25NO3Color and Shape:Greyish-White SolidMolecular weight:279.38Tramadol-d6 Hydrochloride
CAS:Controlled ProductApplications A labelled analgesic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Raffa, R.B., et al.: J. Pharmacol. Exp. Ther., 267, 331 (1993)Formula:C16H19D6NO2•HClColor and Shape:White To Off-WhiteMolecular weight:269.423646Metaxalone
CAS:Metaxalone, sold as Skelaxin by King Pharmaceuticals, is a muscle relaxant for pain from strains and sprains.Formula:C12H15NO3Purity:98.84% - 99.94%Color and Shape:White To Almost White Crystalline Powder SolidMolecular weight:221.25Ref: TM-T1610
10mg47.00€25mg87.00€50mg153.00€100mg279.00€200mg415.00€500mg658.00€1mL*10mM (DMSO)46.00€1-(4-Hydroxy-3,5-dimethoxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:Solid, White to pale reddish yellow powderMolecular weight:196.20199584960938Medetomidine-d3 Hydrochloride
CAS:Controlled ProductApplications Labelled α2-adrenergic agonist. Sedative; analgesic. References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987), Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987), Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988), Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996),Formula:C132H3H13N2·ClHColor and Shape:NeatMolecular weight:239.76N,O-Didesmethyltramadol Hydrochloride
CAS:Controlled ProductFormula:C14H21NO2·ClHColor and Shape:NeatMolecular weight:271.781-(4-(Benzyloxy)-2-hydroxy-6-methoxyphenyl)ethanone
CAS:Purity:98%Molecular weight:272.299987792968751-(2-(CYCLOPROPYLMETHOXY)-6-(4-METHOXYBENZYLOXY)PHENYL)ETHANONE
CAS:Purity:95.0%Molecular weight:326.39199829101561-Hydroxy Ibuprofen (Ibuprofen Impurity L) (Mixture of Diastereomers)
CAS:Impurity Ibuprofen EP Impurity L Applications 1-Hydroxy Ibuprofen (Ibuprofen EP Impurity L) is a degradation product of Ibuprofen. References Forrest, J., et al.: Clin. Pharmacokinet., 7(2), 93 (1982), Shockcor, J., et al.: Xenobiotica, 26, 189 (1996), Nicholls, A., et al.: Chem. Res. Toxicol., 14, 975 (2001), Holmes, E., et al.: Toxicol. Sci., 87, 1 (2005),Formula:C13H18O3Color and Shape:Off-WhiteMolecular weight:222.28Tramadol EP Impurity B HCl
CAS:Formula:C16H23NO·HClColor and Shape:White To Off-White SolidMolecular weight:245.37 36.46Medetomidine Impurity 29 HCl
Formula:C23H28N2·HClColor and Shape:White To Off-White SolidMolecular weight:332.49 36.46Remifentanil Acid Hydrochloride
CAS:Controlled ProductApplications A metabolite of Remifentanil. References Hoke, J., et al.: J. Pharmacol. Exp. Ther., 281, 226 (1997), Bender, J., et al.: J. Pharm. Biomed. Anal., 21, 559 (1999), Manullang, J., et al.: Anesth. Analg., 89, 529 (1999),Formula:C19H26N2O5•HClColor and Shape:NeatMolecular weight:398.882-[[2-(Acetyloxy)benzoyl]oxy]benzoic Acid 2-Carboxyphenyl Ester
CAS:Controlled ProductApplications An analog of Aspirin (acetyl salicylic acid, A187780), which acts as an analgesic, antipyretic, anti-inflammatory, and antithrombotic. References Hart, E.R., et al.: J. Pharmacol. Exp. Ther., 89, 205 (1947), Florey, K., et al.: Anal. Profiles Drug Subs., 8, 1 (1979),Formula:C23H16O8Color and Shape:WhiteMolecular weight:420.373'-(Methylthio)acetophenone
CAS:Purity:97.0%Color and Shape:Liquid, OilMolecular weight:166.24000549316406Xylazine hydrochloride
CAS:Controlled ProductFormula:C12H16N2S·ClHColor and Shape:NeatMolecular weight:256.791-(3-Bromo-4-methylphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:213.074005126953124'-iso-Propylacetophenone
CAS:Purity:97.0%Color and Shape:Liquid, ClearMolecular weight:162.231994628906251-(4-(4-Methyl-1h-imidazol-1-yl)phenyl)ethan-1-one
CAS:Purity:95+%Molecular weight:200.240997314453121-(5-BROMO-2-HYDROXY-4-METHOXYPHENYL)ETHANONE
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:245.07200622558594Meperidine Hydrochloride CII
CAS:Controlled ProductAlfentanil (inn), anileridine (inn), bezitramide (inn), bromazepam (inn), difenoxin (inn), diphenoxylate (inn), dipipanone (inn), fentanyl (inn), etc.Formula:C15H21NO2·HClColor and Shape:White Crystalline PowderMolecular weight:247.15723Benzyl [[[2-[(2,6-Dichlorophenyl)amino]phenyl]acetyl]oxy]acetate (Benzyl Ester of Aceclofenac)
CAS:Formula:C23H19Cl2NO4
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