Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Products of "Ketones and derivatives"
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Ketoprofen EP Impurity K (Mixture of Isomers)
CAS:Formula:C19H20O3Color and Shape:Colorless Semi-SolidMolecular weight:296.371-(3-Bromo-4-methoxyphenyl)ethanone
CAS:Purity:98.0%Color and Shape:Solid, Off-white powderMolecular weight:229.0729980468751-(2-Chloro-5-methoxyphenyl)ethan-1-one
CAS:Purity:97%Color and Shape:SolidMolecular weight:184.61999511718751-(2-Amino-3-bromophenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:214.061996459960944'-Fluoro-3'-hydroxyacetophenone
CAS:Purity:99.0%Color and Shape:SolidMolecular weight:154.13999938964844Nabumetone EP Impurity B
CAS:Formula:C18H18O2Color and Shape:White To Off-White SolidMolecular weight:266.34Trimebutine EP Impurity A HCl
CAS:Formula:C12H19NO·HClColor and Shape:White To Off-White SolidMolecular weight:193.29 36.465'-Chloro-2'-fluoroacetophene
CAS:Purity:98.0%Color and Shape:Solid, Low Melting SolidMolecular weight:172.58000183105471-(3-Bromo-5-chloro-2-hydroxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:249.490005493164061-(2-Chloro-3-methyl-4-(methylsulfonyl)phenyl)ethanone
CAS:Purity:95%Molecular weight:246.7100067138672Medetomidine Impurity 18
CAS:Formula:C15H20N2Color and Shape:White To Off-White SolidMolecular weight:228.344’-Hydroxy Flurbiprofen
CAS:Controlled ProductApplications A metabolite of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Peretto, I., et al.: J. Med. Chem., 48, 5705 (2005), Zgheib, N., et al.: Brit. J. Clin. Pharmacol., 63, 477 (2007),Formula:C15H13FO3Color and Shape:NeatMolecular weight:260.26(2S)-2-(6-Hydroxynaphthalen-2-yl)propanoic Acid (O-Demethylnaproxen)
CAS:Controlled ProductFormula:C13H12O3Color and Shape:NeatMolecular weight:216.23Paracetamol EP Impurity D (Acetaminophen USP Related Compound D)
CAS:Formula:C8H9NOColor and Shape:Off-White SolidMolecular weight:135.173',5'-Difluoro-2'-hydroxyacetophenone
CAS:Purity:98.0%Color and Shape:SolidMolecular weight:172.13099670410156Clonidine hydrochloride
CAS:Controlled ProductFormula:C9H9Cl2N3·ClHColor and Shape:NeatMolecular weight:266.55Ref: 10-F764873
1g58.00€5g131.00€10g150.00€1kg4,738.00€25g333.00€100g885.00€500g2,859.00€100mg31.00€250mg40.00€Medetomidine Impurity 50 HCl
Formula:C13H16N2·HClColor and Shape:White To Off-White SolidMolecular weight:200.29 36.46Tramadol Impurity 4 HCl
Formula:C16H25NO3·HClColor and Shape:White To Off-White SolidMolecular weight:279.38 36.46N-(2-Pyridinyl)oxamic Acid
CAS:Controlled ProductFormula:C7H6N2O3Color and Shape:NeatMolecular weight:166.13Morphine-d3
CAS:Controlled ProductApplications Labelled Morphine (M652290). Principal alkaloid of opium.This is a controlled substance (opiate). Analgesic (narcotic). References Buchwald, M.E., et al.: J. Pharmacol. Exp. Ther., 71, 197 (1941), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 17, 259 (1988),Formula:C172H3H16NO3Color and Shape:WhiteMolecular weight:288.36S-(+)-Ketoprofen
CAS:S-(+)-Ketoprofen, an NSAID, blocks cyclo-oxygenase to reduce pain and inflammation. Sold as Keral, Miracox, Enantyum, and Dolmen in various regions.Formula:C16H14O3Purity:99.44%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:254.28(2RS)-2-[3-(2,4-Dimethylbenzoyl)phenyl]propanoic Acid
CAS:Controlled ProductFormula:C18H18O3Color and Shape:NeatMolecular weight:282.33Racemethorphan hydrobromide
CAS:Controlled ProductStability Hygroscopic Applications (±)-3-Methoxy-17-methylmorphinan Hydrobromide is the racemic mixture of Dextromethorphan (D299445) and Levomethorphan (L375850). Dextromethorphan is an antitussive compound showing analgesic properties; used in cough medication formulations. Levomethorphan is an antitussive medicine, a narcotic and controlled substance. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007); Hafliger, et al.: Helv. Chim. Acta, 39, 2053 (1956); Cox, B.M., et al.: Br. J. Pharmacol. Chemother., 27, 81 (1966); Hou, Chia-Hui; Tzeng, J., et al.: Eur. J. Pharmacol., 544, 10 (2006)Formula:C18H26BrNOColor and Shape:NeatMolecular weight:352.31Ref: 10-F506307
1gTo inquire2gTo inquire5gTo inquire10gTo inquire25gTo inquire100mgTo inquire250mgTo inquire500mgTo inquire5',6',7',8'-tetrahydro-1'H-spiro[cyclohexane-1,2'-quinazolin]-4'(3'H)-one
CAS:Formula:C13H20N2OMolecular weight:220.32Methyl 4-acetyl-2-hydroxybenzoate
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:194.18600463867188Hypaconitine
CAS:Controlled ProductApplications An Aconitine (A189875) analog. Aconitine alkaloid pharmacokinetic analgesic. A highly poisonous, neurotoxic alkaloid. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010), Yan, G., et al.: J. Pharm. Biomed. Anal., 53, 421 (2010),Formula:C33H45NO10Color and Shape:NeatMolecular weight:615.71Medetomidine Impurity 6
CAS:Formula:C12H12N2OColor and Shape:White To Off-White SolidMolecular weight:200.24Tramadol Hydrochloride
CAS:Controlled ProductApplications Tramadol Hydrochloride is an analgesic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Raffa, R.B., et al.: J. Pharmacol. Exp. Ther., 267, 331 (1993)Formula:C16H25NO2·ClHColor and Shape:White To Off-WhiteMolecular weight:299.843-Chloro-4-methoxyacetophenone
CAS:Purity:96.0%Color and Shape:Solid, CrystallineMolecular weight:184.6199951171875(S)-(+)-Ibuprofen Acid Chloride
CAS:Controlled ProductStability Moisture Sensitive Applications (S)-(+)-Ibuprofen Acid Chloride is an intermediate in the synthesis of (S)-(+)-Ibuprofen Propylene Glycol Ester (I140100), a derivative of (S)-(+)-Ibuprofen (I140010), a nonsteroidal anti-inflammatory drug (NSAID). References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),Formula:C13H17ClOColor and Shape:NeatMolecular weight:224.73Buprenorphine-d4 Hydrochloride
CAS:Controlled ProductApplications Buprenorphine-d4 Hydrochloride, is the labeled analogue of Buprenorphine (B689570), an Analgesic that demonstrates narcotic agonist-antagonist properties. References Martin, W.R., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976), Rance, M.J., Biochem. Pharmacol., 25, 735 (1976), Heel, R.C., et al.: Drugs, 17, 81 (1979),Formula:C29D4H37NO4·ClHColor and Shape:NeatMolecular weight:508.131-(2-Hydroxy-3,4-dimethoxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:196.20199584960938Ref: 4Z-M-6878
Discontinued productIsopropyl Salicylate
CAS:Controlled ProductFormula:C10H12O3Color and Shape:NeatMolecular weight:180.20Medetomidine Impurity 52 HCl
CAS:Formula:C13H14N2O2·HClColor and Shape:White To Off-White SolidMolecular weight:230.27 36.461-[2-(4-Morpholinyl)ethyl-d4]-3-(1-naphthoyl)indole JWH 200-d4
CAS:Controlled ProductApplications Labelled JWH-200 (M723765). An analgesic compound which acts as a partial agonist at both the CB1 and CB2 cannabinoid receptors. References Compton, D., et al.: J. Pharmacol. Exper. Ther., 263, 1118 (1992), Tetko, I., et al.: J. Med. Chem., 44, 2411 (2001), Huffman, J., et al.: Bioorg. Med. Chem., 11, 539 (2003),Formula:C25H20D4N2O2Color and Shape:NeatMolecular weight:388.49Azilsartan
CAS:Controlled ProductApplications Azilsartan is an analgesic and antiinflammatory drugs containing angiotensin II antagonists. References Kohara, Y., et al.: J. Med. Chem., 39, 5228 (1996), Plomgaard, P., et al.: Diabetes, 54, 2939 (2005), Fenton, C., et al.: Drugs, 2005, 65, 537,Formula:C25H20N4O5Color and Shape:White To Off-WhiteMolecular weight:456.454'-Chloro-2',6'-difluoroacetophenone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:190.570007324218752',4',5'-Trifluoroacetophenone
CAS:Purity:99.0%Color and Shape:Liquid, ClearMolecular weight:174.12199401855475-Chloro-2-methoxy-3-nitroacetophenone
CAS:Purity:= 99% (GC)Color and Shape:SolidMolecular weight:229.6199951171875(1RS)-[2-(3-Methoxyphenyl)cyclohex-2-enyl]-N,N-dimethylmethanamine Hydrochloride
CAS:Formula:C16H23NO·HClBufexamac EP Impurity D
CAS:Controlled ProductFormula:C12H17NO2Color and Shape:NeatMolecular weight:207.27Buprenorphine-d4
CAS:Controlled ProductApplications Buprenorphine-d4 s the labeled analogue of Buprenorphine (B689570), an analgesic that demonstrates narcotic agonist-antagonist properties. References Martin, W.R., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976); Rance, M.J., Biochem. Pharmacol., 25, 735 (1976); Heel, R.C., et al.: Drugs, 17, 81 (1979)Formula:C292H4H37NO4Color and Shape:NeatMolecular weight:471.66Oxycodone N-Oxide
CAS:Controlled ProductApplications Oxycodone N-Oxide is a metabolite of Oxycodone (O870600), a semisynthetic codeine derivative that has been used both as an analgesic and antitussive. References Moore, K.A. et al.: J. Anal. Toxicol., 27, 346 (2003); Ishida, T. et al.: J. Pharmacobio-Dyn., 5, 521 (1982); Ishida, T. et al.: Drug Metab. Dispos., 7, 162 (1979);Formula:C18H21NO5Color and Shape:White To Light YellowMolecular weight:331.364'-Bromoacetophenone
CAS:Purity:99.0%Color and Shape:Solid, Crystalline Powder or FlakesMolecular weight:199.0469970703125Acetaminophen Mercapturate
CAS:Formula:C13H16N2O5SColor and Shape:White To Off-White SolidMolecular weight:312.341-{4-[(2-Chloro-6-fluorobenzyl)oxy]phenyl}-1-ethanone
CAS:Color and Shape:SolidMolecular weight:278.7099914550781Indoprofen
CAS:Controlled ProductApplications A non-steroidal anti-inflammatory agent used for treatment of pain and inflammation. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Richardson, S., et al.: Anal. Chem., 75, 2831 (2003), Gonzalez, M., et al.: Bioorg. Med. Chem. Lett., 15, 2641 (2005), Panusa, A., et al.: J. Pharm. Biomed. Anal., 43, 1221 (2007),Formula:C17H15NO3Color and Shape:White To Off-WhiteMolecular weight:281.31(1S,2R)-1-Benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl Acetate (Acetoxyphene)
CAS:Formula:C21H27NO2Paracetamol EP Impurity I
CAS:Formula:C8H8O2Color and Shape:Pale Yellow LiquidMolecular weight:136.151-(4-Hydroxy-5-methoxy-2-nitrophenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:211.173004150390621-(2-Amino-phenyl)-propan-1-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:149.1929931640625rac Naproxen-d3
CAS:Controlled ProductApplications Labelled Naproxen. An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)Formula:C142H3H11O3Color and Shape:Off-WhiteMolecular weight:233.28N-Acetyl-4-benzoquinone Imine
CAS:Controlled ProductStability Air Sensitive, Light Sensitive, Moisture Sensitive, Temperature Sensitive Applications N-Acetyl-4-benzoquinone Imine (NAPQI) is a toxic metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3). N-Acetyl-4-benzoquinone Imine can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (A161255) (4). References (1) Jaeschke, H., et al.: Toxicol. Sci., 89, 31 (2006) (2) O’Malley G. F., et al.: J Med Toxicol. 11, 317 (2015)(3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(4) Frey, S. M., et al.: J Med Toxicol. 11, 218 (2015)Formula:C8H7NO2Color and Shape:Light Yellow Dark OrangeMolecular weight:149.15Dimethylketoprofen ((2RS)-2-[3-(2,4-Dimethylbenzoyl)phenyl]propanoic Acid)
CAS:Carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids andtheir derivFormula:C18H18O3Color and Shape:Off-White SolidMolecular weight:282.125591-(5-Bromo-2-iodophenyl)ethanone
CAS:Purity:95+%Color and Shape:SolidMolecular weight:324.94299316406251-(3,5-Dibromophenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:277.94299316406254-Benzyloxypropiophenone
CAS:Purity:98.0%Color and Shape:Liquid, No data available.Molecular weight:240.3020019531253'-Bromo-5'-(trifluoromethyl)acetophenone
CAS:Purity:99.0%Color and Shape:Solid, Low Melting SolidMolecular weight:267.04501342773442-(4-Isopropylphenyl)propanoic acid
CAS:Controlled ProductApplications 2-(4-Isopropylphenyl)propanoic acid is an impurity of Ibuprofen (I140010), a nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer. References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),Formula:C12H16O2Color and Shape:Off-WhiteMolecular weight:192.25Descarboxy 1-Hydroxy Ketorolac
CAS:Impurity Ketorolac EP Impurity A; Ketorolac USP Related Compound B Applications Descarboxy 1-Hydroxy Ketorolac (Ketorolac EP Impurity A; Ketorolac USP Related Compound B) is an impurity of Ketorolac (K235650), an analgesic and anti-inflammatory agent. References Etman, M., et al.: Pharm. Technol., 32, 58 (2008), Chelladurai, S., et al.: Chem. Pharm. Bull., 56, 1596 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),Formula:C14H13NO2Color and Shape:NeatMolecular weight:227.26Medetomidine HCl
CAS:Formula:C13H16N2·HClColor and Shape:White To Off-White SolidMolecular weight:200.29 36.462-Acetylbenzoic acid
CAS:Purity:95.0%Color and Shape:Solid, White to slightly pale yellow crystal powderMolecular weight:164.160003662109384'-Fluoropropiophenone
CAS:Purity:99.0%Color and Shape:Solid, Low Melting SolidMolecular weight:152.16799926757812Ethyl [[[2-[(2,6-Dichlorophenyl)amino]phenyl]acetyl]oxy]acetate (Ethyl Ester of Aceclofenac)
CAS:Formula:C18H17Cl2NO42-(2,6-Dichlorophenylamino)benzoic Acid
CAS:Controlled ProductFormula:C13H9Cl2NO2Color and Shape:NeatMolecular weight:282.12
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