
Ketones and derivatives
Ketones are organic compounds that contain a carbonyl group (C=O) bonded to two carbon atoms, forming a structure where the carbonyl group is flanked by alkyl or aryl groups. In pharmacology, ketones are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Some ketones have anti-inflammatory, analgesic, and antimicrobial properties. Ketone derivatives include compounds in which the carbonyl group is modified, such as enols, which have applications in drug synthesis and as chemical intermediates in the production of other bioactive compounds. Ketone derivatives are used in the design of new medicines, including those for treating neurodegenerative diseases, metabolic disorders, and certain types of cancer, thanks to their specific effects on enzymes and cellular processes.
Products of "Ketones and derivatives"
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Fenoprofen Methyl Ester
CAS:Controlled ProductFormula:C16H16O3Color and Shape:NeatMolecular weight:256.30trans-Capsaicin
CAS:Controlled ProductStability Light Sensitive Applications Capsaicin analogue (C175680). It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Artursson., et al.: J. Pharma. Sci., 73, 1507 (1984), Fu., et al.: Pharma. Res., 2000, 17, 100 (2000),Formula:C18H27NO3Color and Shape:White To Off-WhiteMolecular weight:305.412-Ethylhexyl 2-(3-Benzoylphenyl)propionate (Ketoprofen 2-Ethylhexyl Ester)
CAS:Controlled ProductFormula:C24H30O3Color and Shape:NeatMolecular weight:366.49Mepivacaine Hydrochloride
CAS:Controlled ProductApplications An anti-inflammatory and analgesic agent. Anesthetic (local). Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Reynolds, et al.: Br. J. Anaesth., 43, 33 (1971), Tullar, et al.: J. Med. Chem., 14, 891 (1971), Aberg, G., et al.: Acta Pharmacol. Toxicol., 31, 273 (1972),Formula:C15H22N2O·ClHColor and Shape:WhiteMolecular weight:282.81rac-Medetomidine Impurity 18
CAS:Formula:C15H20N2Color and Shape:White To Off-White SolidMolecular weight:228.341,1'-(4,6-Dihydroxy-1,3-phenylene)-bis-ethanone
CAS:Purity:99.0%Color and Shape:SolidMolecular weight:194.186004638671881-(2-Hydroxy-4,6-dimethoxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:196.201995849609381,3-Diacetyl-4,6-dimethoxybenzene
CAS:Color and Shape:Solid, No data available.Molecular weight:222.240005493164061-(2-Amino-4-methylphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:149.19299316406254'-(Trifluoromethoxy)acetophenone
CAS:Purity:98.0%Color and Shape:Liquid, ClearMolecular weight:204.14799499511721-(4-Acetylphenyl)-2-methyl-1-propanone
CAS:Applications A potential impurity in Ibuprofen (I140000). A degradation product of Ibuprofen arising from oxidative and thermal treatments. References Heikkinen, L., et al.: Acta Pharm. Fenn., 92, 275 (1983), Kepp, D., et al.: Pharm Res., 5, 676 (1997),Formula:C12H14O2Color and Shape:NeatMolecular weight:190.24N,O-Didesmethyl Tramadol Glucuronide (Mixture of Diastereomers)
Formula:C20H29NO8Color and Shape:White To Off-White SolidMolecular weight:411.451-(3-((Dimethylamino)methyl)-4-hydroxyphenyl)ethan-1-one
CAS:Purity:98%Molecular weight:193.24600219726562Ketoprofen D-Lysinate
CAS:Formula:C16H14O3·C6H14N2O2Color and Shape:White To Off-White SolidMolecular weight:254.29 146.19Hydroxy Medetomidine
CAS:Formula:C13H16N2OColor and Shape:White To Off-White SolidMolecular weight:216.28Medetomidine Impurity 23 (N-Benzyl Vinyl Analog)
CAS:Formula:C20H20N2Color and Shape:White To Off-White SolidMolecular weight:288.39P-Diethylaminoacetophenone
CAS:Purity:98.0%Color and Shape:Solid, Pale yellow to reddish yellow powderMolecular weight:191.2740020751953Paracetamol (Acetaminophen) EP Impurity B (Acetaminophen USP Related Compound B)
CAS:Formula:C9H11NO2Color and Shape:White To Off-White SolidMolecular weight:165.196alpha-Oxycodol
CAS:Controlled ProductApplications 6α-Oxycodol is a dihydro metabolite of the analgesic opiate Oxycodone (O870600). References Ishida, T. et al.: Drug Metab. Dispos., 7, 162 (1979); Moore, K.A. et al.: J. Anal. Toxicol., 27, 346 (2003); Lalovic, B. et al.: Clin. Pharmacol. Ther., 79, 461 (2006);Formula:C18H23NO4Color and Shape:NeatMolecular weight:317.402-Acetyl-3,6-difluorobenzoic acid
CAS:Purity:98.0%Color and Shape:SolidMolecular weight:200.14100646972656Ibuprofen Ethyl Ester
CAS:Controlled ProductApplications Ibuprofen Ethyl Ester is a derivative of Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is known to inhibit PGH synthase-1 and PGH synthase-2 with comparable potency. References Gnanarajan, G., et al.: Int. J. Pharma. Sci. Rsch., 1, 27 (2010); Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998);Formula:C15H22O2Color and Shape:Colourless To Light YellowMolecular weight:234.332-(4-Isobutyrylphenyl)propanamide
CAS:Controlled ProductFormula:C13H17NO2Color and Shape:NeatMolecular weight:219.28DL-Lysine Acetylsalicylate
CAS:Controlled ProductApplications Non-steroidal anti-inflammatory drugs (NSAIDs) may inhibit cancer growth. Water soluble, injectable aspirin derivative.Analgesic; antipyretic; anti-inflammatory. References Korttila, K., et al.: Br. J. Anaesth, 52, 613 (1980), Diaz, C., et al.: Clin. Ther., 4, 121 (1981), Wolff, F., et al.: Arch. Gynecol., 233, 15 (1982), Bretagne, J.-F., et al.: Gastroenterol. Clin. Biol., 8, 28 (1984),Formula:C9H8O4·C6H14N2O2Color and Shape:NeatMolecular weight:326.341-(2-Chloro-4-(trifluoromethyl)phenyl)ethanone
CAS:Purity:98.0%Color and Shape:LiquidMolecular weight:222.58999633789062Ref: 4Z-M-6889
Discontinued productN-(2-Pyridinyl)oxamic Acid Hydrochloride
CAS:Controlled ProductFormula:C7H6N2O3Color and Shape:NeatMolecular weight:166.131-(4-(Aminomethyl)phenyl)ethanone hydrochloride
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:185.649993896484383-(1-Methoxyethyl)benzophenone
CAS:Controlled ProductFormula:C16H16O2Color and Shape:NeatMolecular weight:240.301-(4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone
CAS:Purity:95.0%Molecular weight:264.10000610351561-(4-Bromo-5-fluoro-2-hydroxyphenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:233.035995483398444-Acetylbenzoic acid
CAS:Purity:96.0%Color and Shape:Solid, Crystalline PowderMolecular weight:164.160003662109383-[(1RS)-1-Carboxyethyl]benzoic Acid
CAS:Controlled ProductFormula:C10H10O4Color and Shape:NeatMolecular weight:194.181-(3-Difluoromethoxy-phenyl)-ethanone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:186.15800476074221,1',1''-(Benzene-1,3,5-triyl)triethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:204.22500610351562Phenacetin-d3
CAS:Controlled ProductApplications Phenacetin-d3 is the labeled analogue of Phenacetin (P294580), an analgesic, antipyretic; component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens. References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959); Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983)Formula:C10H10D3NO2Color and Shape:NeatMolecular weight:182.23Quinine dihydrochloride
CAS:Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).Formula:C20H26Cl2N2O2Purity:99.45% - 99.97%Color and Shape:White SolidMolecular weight:397.344-[5-(2,4-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
CAS:Formula:C18H16F3N3O2S1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:246.11000061035156Ketorolac Impurity 6 (5-benzoyl-3H-pyrrolizine-1-carbaldehyde)
Formula:C15H11NO2Molecular weight:237.262'-Fluoro-6'-(trifluoromethyl)acetophenone
CAS:Purity:98.0%Color and Shape:LiquidMolecular weight:206.13999938964844rac Methotrimeprazine Maleate Salt
CAS:Controlled ProductApplications Analgesic. References Haddad, P., et al.: Drugs, 62, 1649 (2002), Chiu, P., et al.: J. Pharmacol. Sci., 95, 311 (2004), Dubin, A., et al.: J. Biomol. Screen, 10, 168 (2005),Formula:C23H28N2O5SColor and Shape:NeatMolecular weight:444.54(1RS,2RS)-2-[(Dimethylamino)methyl]-1-(3-hydroxyphenyl)cyclohexanol Hydrochloride
CAS:Formula:C15H23NO2·ClH4-Acetyl-2,3-difluorophenylboronic acid pinacol ester
CAS:Purity:98%Molecular weight:282.08999633789064-Acetyl-2-methoxyphenyl acetate
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:208.212997436523442-[3-(α-Hydroxybenzyl)phenyl]propanoic Acid
CAS:Controlled ProductFormula:C16H16O3Color and Shape:NeatMolecular weight:256.30Cyclohexanone Oxime 97%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Formula:C6H11NOPurity:97%Color and Shape:Off-white to beige to light brown, Crystalline powder or crystals and/or chunksMolecular weight:113.16Dexmedetomidine HCl
CAS:Formula:C13H16N2·HClColor and Shape:White To Off-White SolidMolecular weight:200.29 36.46Ref: 4Z-M-681
Discontinued product4-(3-Acetyl-2-hydroxy-4,6-dimethoxyphenyl)-1-methylpiperidin-3-yl acetate
CAS:Purity:98%Molecular weight:351.398986816406251-(2,3,4-trihydroxyphenyl)ethanone
CAS:Purity:98.0%Color and Shape:SolidMolecular weight:168.14799499511721-(4-Bromo-3-nitrophenyl)ethanone
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:244.044006347656251-(3-Bromo-4-iodophenyl)ethanone
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:324.9429931640625Normorphine (7,8-Didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol)
CAS:Controlled ProductFormula:C16H17NO36Alpha-Naltrexol
CAS:Controlled ProductApplications A metabolite of Naltrexone. References Portoghese, P., et al,: J. Med. Chem., 37, 579 (1994), Ohkawa, S., et al.: J. Med. Chem., 41, 4177 (1998).Formula:C20H25NO4Color and Shape:NeatMolecular weight:343.42Acetaminophen-d3 Glucuronide (Paracetamol-d3 Glucuronide)
Formula:C15H15D3O8Color and Shape:White To Off-White SolidMolecular weight:329.32Ketorolac EP Impurity E (Ketorolac USP Related Compound A)
CAS:Formula:C19H22N2O5Molecular weight:358.391-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-1-one
CAS:Purity:95.0%Molecular weight:260.1400146484375Flunixin-d3
CAS:Controlled ProductFormula:C142H3H8F3N2O2Color and Shape:White To Off-WhiteMolecular weight:299.263’,4’,5’-Trimethoxyacetophenone
CAS:Purity:95.0%Color and Shape:Solid, CrystallineMolecular weight:210.229003906253',5'-Difluoro-4'-hydroxypropiophenone
CAS:Purity:98.0%Color and Shape:SolidMolecular weight:186.1580047607422Pelubiprofen Impurity 2-13C2-d6
Formula:C2413C2H20D6O5Color and Shape:Yellow SolidMolecular weight:426.51N-(3-acetylphenyl)propanamide
CAS:Purity:95.0%Color and Shape:Solid, White powderMolecular weight:191.229995727539063'-Fluoro-4'-hydroxyacetophenone
CAS:Purity:98.0%Color and Shape:SolidMolecular weight:154.13999938964844Felbinac Isopropyl Ester
CAS:Controlled ProductFormula:C17H18O2Color and Shape:NeatMolecular weight:254.323'-Fluoro-2'-methoxyacetophenone
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:168.16700744628906Dihydrocodeine Phosphate
CAS:Controlled ProductApplications Opioid Dihydrocodeine compared to cannabinoid Nabilone was effective and tolerable while both drugs showed mild side effects in patient with chronic neuropathic pain. Analgesics.Controlled substance. References Notcutt, W., et al.: Pharmaceut. Sci., 3, 551 (1997), Hamann, W., et al.: Lancet, 353, 560 (1999), Finnerup, N., et al.: Pain, 118, 289 (2005),Formula:C18H23NO3•H3O4PColor and Shape:NeatMolecular weight:301.3898Detomidine Hydrochloride
CAS:Controlled ProductFormula:C12H14N2·ClHColor and Shape:NeatMolecular weight:222.711-(5-Chloro-4-fluoro-2-hydroxy-3-iodophenyl)ethanone
CAS:Purity:98%Molecular weight:314.4800109863281(2RS)-2-[(Dimethylamino)methyl]cyclohexanone Hydrochloride
CAS:Controlled ProductFormula:C9H17NO·ClHColor and Shape:NeatMolecular weight:191.70Flupirtine maleate
CAS:Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.Formula:C15H17FN4O2·C4H4O4Purity:99.50% - 99.9%Color and Shape:Off-White Crystalline PowderMolecular weight:420.39Normorphine (7,8-Didehydro-4,5α-epoxymorphinan-3,6α-diol)
CAS:Controlled ProductFormula:C16H17NO3Color and Shape:NeatMolecular weight:271.314-Methylsulfonyl Acetophenone
CAS:Formula:C9H10O3SColor and Shape:Off-White SolidMolecular weight:198.24