
Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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4-Ethynylbenzonitrile
CAS:Formula:C9H5NPurity:>97.0%(GC)Color and Shape:White to Light yellow powder to crystalMolecular weight:127.15Dichloro Bisphenol S Isomer
CAS:Controlled ProductApplications Dichloro Bisphenol S Isomer is an endocrine disruptor with estrogenic activity. References Kuruto-Niwa, R., et al.: Environ. Toxicol. Pharmacol., 19, 121 (2005); Zheng, S., et al.: Water Res., 132, 167 (2018)Formula:C12H8Cl2O4SColor and Shape:NeatMolecular weight:319.16Norepinephrine Impurity 59 (Hemioxalate)
Formula:C9H11NO3·5(C2H2O4)Molecular weight:181.19 : 0.5(90.04)5H-Furo[3,2-g][1]benzopyran-5-one,7-[(b-D-glucopyranosyloxy)methyl]-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-4-methoxy-, (S)-
CAS:Formula:C22H28O11Purity:98%Color and Shape:SolidMolecular weight:468.4511N,N-Diethylethylenediamine (2-Diethylaminoethylamine)
CAS:Impurity Metoclopramide EP Impurity E Applications 2-Diethylaminoethylamine (Metoclopramide EP Impurity E) is used in the syntheses of anti-malarials. In addition, it has been seem to induce apoptosis through a caspase-3 dependent pathway. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Kumar, S. et al.: MedChemComm, 3, 489 (2012); del Olmo, E. et al.: Bioorg. Med. Chem. Lett., 12, 2621 (2002);Formula:C6H16N2Color and Shape:ColourlessMolecular weight:116.20Normethadone Hydrochloride
CAS:Controlled ProductApplications Desmethyl analog of Methadone (M225865). A cough suppressant. Controlled Substance. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Eiden, F. et al.: Pharmaz. Zait., 117, 1503 (1972); Anand, D.R.: Arzneim.-Forsch., 15, 564 (1965);Formula:C20H25NO·ClHColor and Shape:NeatMolecular weight:331.882-Methacryloyloxyethyl phosphorylcholine
CAS:Formula:C11H22NO6PPurity:98%Color and Shape:SolidMolecular weight:295.2692414-Amino-N-[[(2RS)-1-ethyl-pyrrolidin-2-yl]methyl]-5-(ethylsulphonyl)-2-hydroxybenzamide
CAS:Formula:C16H25N3O4SOlopatadine USP Related Compound B (Olopatadine N-Oxide)
CAS:Formula:C21H23NO4Color and Shape:White To Off-White SolidMolecular weight:353.42Keto Pioglitazone-d4 (M-III)
CAS:Controlled ProductApplications Keto Pioglitazone-d4 (M-III) is the labeled analogue of Keto Pioglitazone (M-III) (K200600), a metabolite of Pioglitazone (P471000), which is used as an antidiabetic. References Tanis, S.P., et al.: J. Med. Chem., 39, 5053 (1999); Hofmann, C., et al.: Endocrinology, 129, 1915(1991); Kobayashi, M., et al.: Diabetes, 41, 476 (1992); Kawaamori, R., et al.,: Diabetes Res. Clin. Pract., 41, 35 (1998)Formula:C192H4H14N2O4SColor and Shape:Off White SolidMolecular weight:374.45Dipyridamole Tripiperidine
CAS:Controlled ProductImpurity Dipyridamole EP Impurity A Applications Dipyridamole Tripiperidine (Dipyridamole EP Impurity A) is a Dipyridamole (D492625) impurity. References Bakken, G.A., et al.: J. Med. Chem., 43, 4534 (2000),Formula:C25H40N8O2Color and Shape:NeatMolecular weight:484.64Gestonorone Capronate
CAS:Controlled ProductFormula:C26H38O4Color and Shape:NeatMolecular weight:414.58Granisetron HCl
CAS:Formula:C18H24N4O·HClColor and Shape:White To Off-White SolidMolecular weight:312.42 36.46Ref: 4Z-M-230001
Discontinued product(R)-Rivastigmine
CAS:Controlled ProductImpurity Rivastigmine EP Impurity D Applications (R)-Rivastigmine (Rivastigmine EP Impurity D) is a carbamate inhibitor of acetylcholinesterase used as a treatment of Alzheimer’s disease. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Lucangioli, S. E., et al.: J. Chromatogr. A, 1081, 31-35 (2005); Bar-On, P., et al.: Biochem., 41, 3555-3564 (2002);Formula:C14H22N2O2·C4H6O6Color and Shape:NeatMolecular weight:400.42Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
CAS:Formula:C45H56N7O9PPurity:95%Color and Shape:SolidMolecular weight:869.9414Betahistine-13C-d3 DiHCl
CAS:Formula:C713CH9D3N2·2HClColor and Shape:Pale Orange SolidMolecular weight:140.21 2*36.46Riociguat
CAS:Formula:C20H19FN8O2Purity:>95.0%(HPLC)(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:422.42N-(Chloromethylene)-N-Methylmethanaminium Phophorodichloride
Formula:C3H7ClN·Cl2O2PMolecular weight:92.55 133.87N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine
CAS:Formula:C22H24ClFN4O3Purity:98%Color and Shape:SolidMolecular weight:446.9024Clopidogrel Impurity 57
Formula:C16H16ClNO5S2Color and Shape:White To Off-White SolidMolecular weight:401.884-Pyridinecarboxylic acid, hydrazide
CAS:Formula:C6H7N3OPurity:%Color and Shape:SolidMolecular weight:137.1393Ceftriaxone 3-Ene Isomer Disodium Salt
Controlled ProductApplications Ceftriaxone 3-ene Isomer Disodium Salt is an impurity of Ceftriaxone(C244995) which is an antibacterial, a third-generation cephalosporin. References Reiner, R., et al.: J. Antibiot., 33, 783 (1980)Formula:C18H16N8Na2O7S3Color and Shape:Off-WhiteMolecular weight:598.54N-Nitroso Mefenamic Acid Sodium Salt
CAS:Formula:C15H13N2O3·NaColor and Shape:Pale Yellow SolidMolecular weight:269.28 22.993-(Isonicotinoylhydrazonomethyl) Rifamycin
CAS:Applications An impurity of Rifampamycin (R508000).Formula:C44H52N4O13Color and Shape:NeatMolecular weight:844.90