Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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Dichlorothiophene Carboxylic Acid (3,5-dichlorothiophene-2-carboxylic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C5H2Cl2O2SColor and Shape:White Off-White SolidMolecular weight:195.91526Amlexanox
CAS:Formula:C16H14N2O4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:298.303'-Desethoxy Drotaverine HCl
CAS:Formula:C22H27NO4·HClColor and Shape:Off-White SolidMolecular weight:369.46 36.46γ-Aminobutyric Acid Tartrate
CAS:Formula:C4H9NO2·C4H6O6Color and Shape:White To Off-White SolidMolecular weight:103.12 150.09Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
CAS:Formula:C18H21NO4SMolecular weight:347.434-(p-Chloro-a-phenylbenzyl)-1-piperazineethanol Dihydrochloride
CAS:Impurity Cetirizine EP Impurity G Dihydrochloride Applications 4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine. References Rezaei, Z. et al.: Archiv. Pharm., 344, 658 (2011);Formula:C19H23ClN2O·2ClHColor and Shape:WhiteMolecular weight:403.7721-Dehydrocorticosterone (mixture of the aldehyde and the hydrated form)
CAS:Formula:C21H28O4Color and Shape:NeatMolecular weight:344.442-((1R,4R)-4-(4-Chlorophenyl)cyclohexyl)-1-oxo-1H-indene-3-carboxylic Acid
Applications 2-((1r,4r)-4-(4-Chlorophenyl)cyclohexyl)-1-oxo-1H-indene-3-carboxylic Acid is the Indene isomer of Atovaquone (A793500)Formula:C22H19ClO3Color and Shape:NeatMolecular weight:366.847-Cyclopentyl-N,N-dimethyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
Controlled ProductFormula:C23H29N9O2Color and Shape:NeatMolecular weight:463.551-((3,4-Dimethoxyphenethyl)amino)-3-(m-tolyloxy)propan-2-ol hydrochloride
CAS:Formula:C20H28ClNO4Purity:98%Color and Shape:SolidMolecular weight:381.893620000000067-Hydroxy Propranolol HCl
CAS:Formula:C16H21NO3·HClColor and Shape:Off-White SolidMolecular weight:275.35 36.46Dimethyl Maleate
CAS:Controlled ProductApplications Dimethyl Maleate is a reactant used in the synthesis of ethylene-propylene copolymer. References Passaglia, E., et. al.: Eur. Polymer J., 44, 1296 (2008)Formula:C6H8O4Color and Shape:ColourlessMolecular weight:144.13Formoterol Fumarate(Mixture of Diastereomers)
CAS:Controlled ProductApplications Formoterol fumarate (mixture of diastereomers) is an impurity of Formoterol fumarate dihydrate (F693400). References Yoshida, T., et al.: Pharmacometrics, 26, 811 (1983), Bartow, R.A., et al.: Drugs, 55, 303 (1998),Formula:C19H24N2O4•C4H4O4Color and Shape:NeatMolecular weight:326.433Lurasidone Opened Imide (Mixture of Diastereomers)
CAS:Controlled ProductApplications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia. References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);Formula:C28H38N4O3SColor and Shape:NeatMolecular weight:510.69N-Carbamoyl L-Glutamic Acid
CAS:Formula:C6H10N2O5Purity:>95.0%(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:190.16Bupivacaine HCl
CAS:Formula:C18H28N2O·HClColor and Shape:White To Off-White SolidMolecular weight:288.44 36.46Alogliptin Related Compound 30
Formula:C10H16N4O2Color and Shape:Off-White SolidMolecular weight:224.263,5-Diaminobenzoic acid dihydrochloride
CAS:Formula:C7H10Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:225.0725Migalastat HCl
CAS:Formula:C6H13NO4·HClColor and Shape:White To Off-White SolidMolecular weight:163.17 36.46N,N-Diethylglycine Sodium Salt
CAS:Formula:C6H12NNaO2Purity:>97.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:153.16Zolmitriptan N-Oxide
CAS:Controlled ProductImpurity Zolmitriptan USP Related Compound E Applications A metabolite of Zolmitriptan. Zolmitriptan USP Related Compound E. References Forrester, L., et al.: Biochem. J., 281, 359 (1992), Newton, D., et al.: Drug Metab. Dis., 23, 154 (1995), Dixon, R., et al.: Clin. Drug Invest., 15, 515 (1998), Whale, R., et al.: Psychopharmacology, 145, 223 (1999), Wild, M., et al.: Xenobiotica, 29, 847 (1999),Formula:C16H21N3O3Color and Shape:NeatMolecular weight:303.364,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
CAS:Controlled ProductApplications 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol is an intermediate for the preparation of Valdecoxib.Formula:C16H15NO2Color and Shape:NeatMolecular weight:253.30Alfuzosin-13C-d3
CAS:Formula:C1813CH24D3N5O4Color and Shape:White To Off-White SolidMolecular weight:393.47O-Desmethyl Apixaban Sulfate Sodium Salt
CAS:Controlled ProductStability Hygroscopic Applications O-Desmethyl Apixaban Sulfate is an impurity of Apixaban (A726700), is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);Formula:C24H22N5NaO7SColor and Shape:White To Off-WhiteMolecular weight:547.516
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