Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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N-Didesmethyl Bedaquiline-13C-d3 (Mixture of Enantiomers)
CAS:Formula:C2913CH24D3BrN2O2Molecular weight:531.47β-Alanine Ethyl Ester Hydrochloride
CAS:Formula:C5H11NO2·HClPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:153.616-Fluoro-2-nitrobenzoic Acid
CAS:Formula:C7H4FNO4Purity:>98.0%(GC)(T)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:185.114-Aminocarminic Acid, >85%
CAS:Controlled ProductApplications 4-Aminocarminic Acid is an impurity of Carminic Acid (C183620). which is a red glucosidal hydroxyanthrapurin, it is produced naturally within some insects as a defense mechanism. Dyes and metabolites, Environmental Testing. References Enoch, S., et al.: Chem. Res. Toxicol., 23, 1547 (2010), Valianou, L., et al.: Anal. Bioanal. Chem., 396, 3115 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),Formula:C22H21NO12Purity:>85%Color and Shape:NeatMolecular weight:491.4023-Butynyl p-Toluenesulfonate
CAS:Formula:C11H12O3SPurity:>97.0%(GC)Color and Shape:Light yellow to Brown clear liquidMolecular weight:224.27N,N-Dimethylpropargylamine
CAS:Formula:C5H9NPurity:>98.0%(GC)(T)Color and Shape:Colorless to Light orange to Yellow clear liquidMolecular weight:83.13Anhydro Simvastatin ((1S,3R,7S,8S,8aR)-3,7-Dimethyl-8-[2-[(2R)-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate)
CAS:Lactones nesoiFormula:C25H36O4Color and Shape:Off-White PowderMolecular weight:400.26136N6-[(Allyloxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine
CAS:Formula:C25H28N2O6Purity:>96.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:452.51Fmoc-D-Aspartic acid β-tert-butyl ester
CAS:Formula:C23H25NO6Purity:98%Color and Shape:SolidMolecular weight:411.44773-(5-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
CAS:Formula:C13H13N3O3Purity:>95.0%(T)(HPLC)Color and Shape:White to Gray powder to crystalMolecular weight:259.273-Amino-2-chloro-propenal
CAS:Controlled ProductStability Hygroscopic Applications 3-Amino-2-chloro-propenal is a chemical reagent in the synthesis of a COX-2 specific inhibitor. References Davies, I. et al.: J. Org. Chem., 65, 8415 (2000);Formula:C3H4ClNOColor and Shape:NeatMolecular weight:105.52(R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester
CAS:Controlled ProductApplications (R)-N-(1-Carboxyethyl)-D-norvaline 1-Ethyl Ester is an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive. References Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)Formula:C10H19NO4Color and Shape:NeatMolecular weight:217.26Terbutaline Impurity 16 (Mixture of Diastereomers)
Formula:C48H51NO6HClMolecular weight:737.94 : 36.46Glycopyrrolate Erythro Isomer ((RS)-3-[(RS)-2-cyclopentyl-2-hydroxy-2-phenylacetoxy]-1,1-dimethylpyrrolidinium bromide)
Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoiFormula:C19H28BrNO3Color and Shape:White PowderMolecular weight:398.33Desloratadine Pyridine N-Oxide
CAS:Formula:C19H19ClN2OColor and Shape:White To Off-White SolidMolecular weight:326.82Imatinib EP Impurity C-d8 (N-Desmethyl Imatinib-d8)
CAS:Formula:C28H21D8N7OColor and Shape:Off-White To Pale Yellow SolidMolecular weight:487.64N-Ethyl-N-(2-hydroxyethyl)perfluorooctylsulphonamide-d9
CAS:Controlled ProductFormula:C12HD9F17NO3SColor and Shape:White To Off-WhiteMolecular weight:580.31Methyl mycophenolate impurity E
CAS:Methyl mycophenolate impurity E is a reactive, propargylamine-containing, monosodium salt with immunosuppressive properties. It is used in the treatment of cancer by inhibiting the production of white blood cells, which are needed to fight infection. Methyl mycophenolate impurity E has shown antitumor activity and can be used for the treatment of some types of cancer. It is metabolized in vivo to methyl mycophenolate and inhibits protein synthesis by alkylating DNA.Formula:C18H22O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:334.36 g/mol7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one 4-Oxide (Demoxepam)
CAS:Formula:C15H11ClN2O2a,a'-[(Methylimino)di-3,1-propanediyl]bis[3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile
CAS:Controlled ProductApplications α,α'-[(Methylimino)di-3,1-propanediyl]bis[3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile is an impurity of verapamil hydrochloride, a theraputic drug. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Vijayabaskar, S. et al.: Jour. of Pharm. and Bio. Ana. 137, 189-195 (2017)Formula:C33H47N3O4Color and Shape:NeatMolecular weight:549.74N-Desmethyl N-Nitroso Dalbavancin (Mixture of B0+A0+A1+B1+B2)
Formula:C87H97Cl2N11O29C86H95Cl2N11O29Molecular weight:1831.68(B0) 1817.65(A0)+Carglumic Acid Related Compound C ((S)-2-[(S)-4-Carboxy-2-ureidobutanamido]pentanedioic acid)
CAS:Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoiFormula:C11H17N3O8Color and Shape:Off-White PowderMolecular weight:319.10156N-(2-Succinyl) Fluvoxamine
CAS:Stability Moisture Sensitive Applications Fluvoxamine impurity. References Wieling, J., et al.: J. Chromatogr., 635, 195 (1993), Hilhorst, M., et al.: J. Pharm. Biomed. Anal., 16, 1251 (1998),Formula:C19H25F3N2O6Color and Shape:NeatMolecular weight:434.41Lovastatin-d3 Hydroxy Acid Sodium Salt
CAS:Controlled ProductStability Hygroscopic Applications A labelled metabolite of Lovastatin.Formula:C24H34D3NaO6Color and Shape:NeatMolecular weight:447.56Colchicoside
CAS:Controlled ProductApplications A significantly toxic Colchicine analog with no anti-inflammatory properties. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Chaudhuri, P., et al.: J. Nat. Prod., 56, 1174 (1993), Gomez, D., et al.: J. Chem. Ecol., 29, 1117 (2003), Poutaraud, A., et al.: Environ. Exper. Botany, 54, 101 (2005),Formula:C27H33NO11Color and Shape:Light YellowMolecular weight:547.55Celecoxib N-Des(benzenesulfonamide)
CAS:Controlled ProductApplications Celecoxib N-Des(benzenesulfonamide) is a useful intermediate in the preparation of Celebrex using continuous flow reaction modules and offline Ullmann coupling. References Britton, J., et al.: Eur. J. Org. Chem., 44, 6566 (2017)Formula:C11H9F3N2Color and Shape:NeatMolecular weight:226.2Linarine
CAS:Controlled ProductImpurity Diosmin EP Impurity E Stability Hygroscopic Applications Linarine (Diosmin EP Impurity E) is a naturally occurring flavone glycoside that was identified to possess potential sedative and anticonvulsant properties. References Nugroho, A., et al.: Arch. Pharma. Res., 36, 51 (2013); Jung, H.A., et al.: Arch. Pharma. Res., 35, 1021 (2012); Shen, H.J., et al.: J. Med. Plants. Res., 5, 6555 (2011);Formula:C28H32O14Color and Shape:White To Light BeigeMolecular weight:592.5454-Amino-1-[10-[(2-methyl-4-quinolyl)amino]decyl]quinaldinium Iodide Hydriodide
CAS:Controlled ProductFormula:C30H39IN4•x(HI)Color and Shape:NeatMolecular weight:582.56127912-Hydroxynaphthalene-1,4-dione
CAS:Formula:C10H6O3Purity:95%Color and Shape:SolidMolecular weight:174.1528Boc-DL-Pro-OH
CAS:Formula:C10H17NO4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:215.252-Bromo-1-(3-chlorophenyl)propan-1-one
CAS:Formula:C9H8BrClOPurity:>95.0%(GC)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:247.52(S)-3-[2-(2-ethoxyethoxy)ethoxy] Piperidine HCl
CAS:Formula:C11H23NO3·HClMolecular weight:217.31 36.46
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